Basic Information

Gene Symbol
-
Assembly
GCA_963989295.1
Location
OZ022394.1:10263094-10273515[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0001 0.012 16.7 1.4 1 23 459 481 459 481 0.96
2 18 2.2e-05 0.0025 18.9 1.9 1 20 487 506 487 509 0.94
3 18 3.4e-05 0.004 18.2 0.7 1 23 515 537 515 537 0.98
4 18 8.3e-05 0.0098 17.0 4.4 1 21 543 563 543 565 0.95
5 18 2.6e-05 0.003 18.6 4.6 1 23 571 593 571 593 0.99
6 18 2.6e-05 0.003 18.6 5.3 1 23 599 621 599 621 0.97
7 18 9.8e-06 0.0012 19.9 7.1 1 23 627 649 627 649 0.97
8 18 9.6e-08 1.1e-05 26.3 2.7 1 23 655 677 655 677 0.98
9 18 7.1e-05 0.0083 17.2 6.7 1 23 683 705 683 705 0.97
10 18 2.2e-05 0.0026 18.8 5.8 1 23 711 733 711 733 0.98
11 18 5.8e-07 6.8e-05 23.8 2.9 1 23 739 761 739 761 0.98
12 18 8.6e-06 0.001 20.1 7.8 1 23 767 789 767 789 0.98
13 18 2.7e-05 0.0032 18.5 9.1 1 23 795 817 795 817 0.98
14 18 3.6e-05 0.0042 18.2 7.5 1 23 823 845 823 845 0.98
15 18 0.0017 0.2 12.9 8.8 1 21 851 871 851 873 0.94
16 18 1.3e-05 0.0015 19.5 0.4 1 23 879 901 879 901 0.98
17 18 0.031 3.7 8.9 4.5 1 23 911 933 911 933 0.98
18 18 5.1e-07 5.9e-05 24.0 1.3 1 23 939 961 939 961 0.97

Sequence Information

Coding Sequence
ATGAACGGGGAGCAGCATGCACTGCCAGCGACTACGCAGGGGCAGCAAGAGGAAGTAAACGTGGGTCAAAGCGGTCGCCCTTCGTATCCAAGTGGATTGGCGACTGGATCCGGTCTTGGGAACGTAGGAAGTATTCCCCATTCTTCGGCAGATCTTCGCGTAGGTACAGCAGTAGCGTTAGCCTCTTCGGTAGCTAAATATTGGGTCCTGACCAATCTATTTCCTGGGGCGCCGCTTCCTCAGGTTTCTGTATATCACCACCCCCATCATAATTCTTCGCACAGAAGTGGCTCTGGCGGCGGTGGTGATTCCGCTAATAAGGAATCTTCGGCTTCGTCGTTATCTCAAGAAATGGCATTGGCTCAAAATTCTCACCAACAGGCATCTACTTCGCATCATCATCAACAAACTCCGGTTAATAACAACAATCAACATAACTCCCTACACCCAAATTCGCAGaTACCAGTATCGCTGCCTGGTCTAAGTTTAGACGGTACCCACATACCCCCAAGTGTAAGCCACTTGCATGCGGCGCACGCTCAAATGCAGCAACAAATGCAGTCTCAGCAGCAATTgcatcagcagcagcaacagcagcagcagcagcaacaacaacaacaacaacaacaacaacagcagcagcaacagcaacaatcGCATCATCAAATGCAGAATCATCAGACTAGTCAAAACAGCGGACACAGTCCGCAAAATCAGTCTAGCAGTCagagagatgaaaataaagtaaaagaCGAAGGTGGGAGCTGCACGACTGAAAGATGCAGCGATAATCAAGTACATTGTCAGGTCCAATGCGATCTTCAACTACAGCCTCAGGCTCAATCGGATATGCAACAGAATATtatgcagcagcagcagcaacaaatCGGCGTCAATATCGGTGGGAATAACACCGCCGATGGAGGAAATCAGAACAATTCTGATACattgaaaactgaaaaggATAAGGAGATGCGTCAGCACAGTATGGCACAATTCCAGTTACCTGATCTTAAACCTGGCGGACATATGATGGATGTCAGAACGGCGGACGGTTCAGTTGTGAAAATAAGTGCAGGGAGCGAGCAGGATCTCGCTAAGACACTTGGCGTTGAGATGGTACAAAATATGTACAAGGTCAACGTCGAAGATATAAACCAGCTTCTGGCATACCACGAGGTTTTTGGTAAACTTCAGAGCGAGATAGCTGCGGGAACAACGCTGGTGGGTGGGACTGTTCCCACTCAGACGGTTACCACTATACAAAATGGTACCCCCATCGTGCAGCAAGTtcagttgaataaatttgatataaaaactAGCGACGGAGAAGCTACCCCTGGACCAAGCGCTTCTCCTGTATCTGTAGGCAGCCACGCTTGCGAAGTATGCGGAAAAATATTCCAGTTTCGATATCAACTTATCGTACATCGCAGATACCACACCGAAAGAAAACCTTTTACGTGCCAGGTGTGCGGTAAAGCATTTACAAATGCGAATGACCTGACTCGTCACGGTAAATGCCACCTCGGTGGATCGATGTTTACTTGCGCGGTATGTTTTCATGTATTCGCTAACGCGCCGTCATTGGAACGACATATGAAGAGACACGCGACTGACAAACCCTACAACTGTACAGTTTGTGGAAAAAGCTTTGCCAGGAAGGAACATCTGGATAATCACACTCGATGTCATACTGGCGAAACACCATACAGatgtCAATACTGCGCGAAGACCTTCACTCGCAAGGAACACATGGTAAACCACGTTCGGAAGCATACCGGCGAGACTCCGCATCGTTGCGATATATGCAAGAagagttttacaagaaaagaGCATTTCATGAATCACGTAATGTGGCATACCGGCGAAACTCCGCATCACTGCCAGGTATGCGGGAAGAAATATACCCGCAAAGAACATCTCGCCAATCATATGCGTTCCCATACCAACGATACACCCTTCCGTTGTGAAATTTGTGGTAAGTCGTTCACGCGGAAGGAGCACTTCACGAACCACATAATGTGGCATACAGGAGAGACTCCGCATCGCTGCGACTTCTGCTCAAAGACGTTCACACGGAAGGAGCACCTATTGAATCACGTTCGCCAGCACACGGGTGAGTCCCCACACCGATGCGGCTTCTGCTCCAAATCGTTCACCAGAAAGGAACACCTTGTTAATCACATCCGCCAACACACAGGGGAGACGCCATTCCGTTGCCAGTACTGTCCGAAGGCTTTCACACGTAAGGATCACTTGGTAAATCACGTCAGGCAGCACACGGGTGAGTCACCGCACAAGTGCCAGTATTGCACCAAATCGTTCACGCGGAAGGAACATTTGACCAATCACGTGCGTCAACATACAGGCGAATCGCCACACCGATGTCACTTCTGCTCCAAGTCGTTTACTCGAAAGGAACATCTGACTAATCATGTTCGTATTCATACCGGAGAATCGCCTCACAGATGCGAGTTCTGCCAGAGGACATTTACAAGGAAAGAACATCTCAACAATCATCTTCGACAACATACAGGCGAATCTTCCCACTGCTGCAACGTCTGTTCCAAACCATTTACCAGAAAGGAGCACCTCGTCAATCATATGAGATGTCATACCGGCGAACGTCCCTTCGTATGTACCGAATGCGGCAAGAGTTTCCCACTAAAAGGAAATCTCCTTTTCCATATGCGATCCCACAACAAAGGAAGCAACGCGGAAAGACCATTCAGATGCGATCTTTGTCCAAAAGATTTTATGTGCAAAGGTCACTTGGTCTCTCACAGACGTTCTCATTCGGACGAAAGGCCCCATAGCTGTCCTGATTGCGGTAAAACTTTCGTAGAAAAAGGAAACATGCTCAGGCATCTTAGAAAACATGCAGCCGAAGGACCTCCCACTCAAGTCACTACACCTTCGGCTATACCGCAGCCCGGTGTTCTCCCAATTCCAACGGCTGCCGTTTTGGTTGGACATCCTCTGGCTCCTCCAGCACCACCCGTTGTGCCCCAACATACAGTAGTCGTCCCGACGCCACCCGGAGTGTTGACTTCgtattag
Protein Sequence
MNGEQHALPATTQGQQEEVNVGQSGRPSYPSGLATGSGLGNVGSIPHSSADLRVGTAVALASSVAKYWVLTNLFPGAPLPQVSVYHHPHHNSSHRSGSGGGGDSANKESSASSLSQEMALAQNSHQQASTSHHHQQTPVNNNNQHNSLHPNSQIPVSLPGLSLDGTHIPPSVSHLHAAHAQMQQQMQSQQQLHQQQQQQQQQQQQQQQQQQQQQQQQQSHHQMQNHQTSQNSGHSPQNQSSSQRDENKVKDEGGSCTTERCSDNQVHCQVQCDLQLQPQAQSDMQQNIMQQQQQQIGVNIGGNNTADGGNQNNSDTLKTEKDKEMRQHSMAQFQLPDLKPGGHMMDVRTADGSVVKISAGSEQDLAKTLGVEMVQNMYKVNVEDINQLLAYHEVFGKLQSEIAAGTTLVGGTVPTQTVTTIQNGTPIVQQVQLNKFDIKTSDGEATPGPSASPVSVGSHACEVCGKIFQFRYQLIVHRRYHTERKPFTCQVCGKAFTNANDLTRHGKCHLGGSMFTCAVCFHVFANAPSLERHMKRHATDKPYNCTVCGKSFARKEHLDNHTRCHTGETPYRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQVCGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCGFCSKSFTRKEHLVNHIRQHTGETPFRCQYCPKAFTRKDHLVNHVRQHTGESPHKCQYCTKSFTRKEHLTNHVRQHTGESPHRCHFCSKSFTRKEHLTNHVRIHTGESPHRCEFCQRTFTRKEHLNNHLRQHTGESSHCCNVCSKPFTRKEHLVNHMRCHTGERPFVCTECGKSFPLKGNLLFHMRSHNKGSNAERPFRCDLCPKDFMCKGHLVSHRRSHSDERPHSCPDCGKTFVEKGNMLRHLRKHAAEGPPTQVTTPSAIPQPGVLPIPTAAVLVGHPLAPPAPPVVPQHTVVVPTPPGVLTSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2