Basic Information

Insect: Tribolium castaneum
Gene Symbol: prdm10
Assembly: GCA_000002335.3
Location: NC:13712681-13719275[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 1.9e-05 0.0011 18.8 0.1 2 23 414 435 413 435 0.96

2 13 0.58 34 4.7 0.1 1 14 460 473 460 485 0.82

3 13 0.0035 0.2 11.7 0.4 1 23 503 525 503 525 0.92

4 13 1.5e-05 0.00088 19.1 1.0 1 23 536 558 536 558 0.97

5 13 3.9e-06 0.00023 21.0 1.8 1 23 569 591 569 591 0.98

6 13 3.3e-06 0.0002 21.2 0.6 2 23 600 621 599 621 0.97

7 13 0.051 3 8.0 0.7 1 20 628 647 628 650 0.90

8 13 0.0012 0.073 13.1 2.8 1 23 656 679 656 679 0.96

9 13 0.0027 0.16 12.0 2.2 1 23 684 706 684 706 0.96

10 13 0.00087 0.051 13.6 4.0 1 23 712 735 712 735 0.89

11 13 0.0018 0.11 12.5 1.7 1 23 771 794 771 794 0.97

12 13 0.00014 0.0081 16.1 3.9 1 23 816 839 816 839 0.97

13 13 0.0012 0.073 13.1 3.8 3 23 879 900 877 900 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	1.9e-05	0.0011	18.8	0.1	2	23	414	435	413	435	0.96
2	13	0.58	34	4.7	0.1	1	14	460	473	460	485	0.82
3	13	0.0035	0.2	11.7	0.4	1	23	503	525	503	525	0.92
4	13	1.5e-05	0.00088	19.1	1.0	1	23	536	558	536	558	0.97
5	13	3.9e-06	0.00023	21.0	1.8	1	23	569	591	569	591	0.98
6	13	3.3e-06	0.0002	21.2	0.6	2	23	600	621	599	621	0.97
7	13	0.051	3	8.0	0.7	1	20	628	647	628	650	0.90
8	13	0.0012	0.073	13.1	2.8	1	23	656	679	656	679	0.96
9	13	0.0027	0.16	12.0	2.2	1	23	684	706	684	706	0.96
10	13	0.00087	0.051	13.6	4.0	1	23	712	735	712	735	0.89
11	13	0.0018	0.11	12.5	1.7	1	23	771	794	771	794	0.97
12	13	0.00014	0.0081	16.1	3.9	1	23	816	839	816	839	0.97
13	13	0.0012	0.073	13.1	3.8	3	23	879	900	877	900	0.96

Sequence Information

Coding Sequence: ATGGATACGATTGTGCAAGGGCCCCCCGGCGAAGGGGCCCAGGACTTGAACCTAGTCGACGCCGCTTGGAGCACCCAAAACTCGCAAGAGATCGTAAACAACAACTCTATCCTTTATATTGCTGTCGAGTACATCAAAGACGAGTACAAGATGGAGTCGGCGGTCAACTTGCCGCCCCCGGAGAACTTCGCCGATTTCGAGCAGCACGTGAGCCCCCTCGACCCCAACATGAGCTCCGTGGCGCGCTACAGCCCCGTGTACAGCGAGCCCACCACTGAGTACAACCCCGTGGTGATCCACCACCTGGTCCAGCCAAATTCCAGTCAGAGCGATATTAATAATTTAGCCCCCGAACCCATGCCTGTCTTATGCAATAACGACATCCGGGAAGTCGTTGATAACCATTTTTTGCAAATGGTCAACTCCGGGAACCAGCTGCAGGTGGTGCCCCCCAACGAGCAGGAGGTGGCGCTGCTGATAACTGACCAGGAAACGGGCATTTCGTACAGCGTAAGGGGGCAGGAGTTTCTCGTTGAGGACGAGCAGTTGCTAAATGCGCTCAGTCCCGACCCGCTTTTGGACCCCCATTTGCTGGCACTTGACGAAAACGCGCTCAAAACCGAGCTGGGGGATGAAATAATTAACTCAACCGTTAACACAGCCGTTAATAACTATATCACGAGTTTGAGTGCGGCCGTTGATAACGACGGACAGTACAAGATGGAGACCAGGAGGCAGAAACAGAACGAGGTCGAGTTTGAAGATCAGTTATTGTCCAAGGTTTATAGCATTGTGGACAAGCCGGTGCCGTCGAGGGCCAGGGCCACGCTGCCGGAGTCGTATCTCACTCTGAGCAAGGTGGACCAAGCACTGGGCGTTTTTGCCAAGAAAACAATCCCTCGAAGCACACAGTTCGGACCTTTGACTGGAATTCTGAAACCGAGCACCGAACGTTTGAAAAACGGTCCGACGTCTTTGCAATTTTTTATCGAAGATGAGAACAACGTCGTGTCACAGATTGATGTTTCGGATGAAAATGCTTCGAATTGGATGCGTTTTATCAGACAAGCGACGAATTATAACGAGCAAAATTTATTGATAACGCAGGAAGGCAACTCTTTGTATTTCACAACGACGAGGAGCATTCTTCCGAAGCAGGAACTGAAGGTTGGCTACAGTGTGCCCTACGCCACCCGTCACAAATTATCAATTCTGGTCCCCGAGGAAGAAAAATCGTGGCCTTGTTACGAATGTTCGGAAACTTTTGCCTCCTCTGATGAATTACAGAAACATTTGAACATCCACGACAGTGACGAGGAAAACAAATGGAAGAAAAAGAATTTAAAAAATAAGAAAAAAATCCCAAAAAGTGAGACGTTTCAATGTAATAATTGCAACGAACTGTTCGTCCAGCCGGGAAAAGTCGCCCTCAGGCAACACTTGATTGAAAAACACCTTTTGAGCGGTTTGGACTTGATCGATCAGTATTTTTCTTCAGTCATGAATTACAAGTGCGATAAATGCGAATTGGTTTTCAATTCGGAACCTTTGTTAAAAATCCATAACTATCTTCATGATTCGGACAGTTCGGACGAACAAACGAATCATGTTTGTCCCAACTGTCAGAAAAAATTCCCAACGCAACGCCAACTTGTTACGCACGTCGCTACGCACGCACTTACCAAAAAACCGGAAACGGAAACGTTCAAGTGTCCAGTGTGCCACAAAATGTTCGCTATGCGCGAGCGACTAAGGCGCCACATGCTGGTGCACGGCTCTGACGACTCGAAGCCTCTCCAGTGTAAAACTTGCAATAAACGCTTTGTGAACAATTCGGCGCTCGCCGGCCACATCAAGACCCACCTTGTGGGCAAAAAAATCTTCGAATGTCCCATTTGTAAAGAAAATTTCGACCACGTCCTAAAACTGAAACTCCACGTCCCCAAACACTGCGAAAATAACACATACTCGTGCCCTCATTGCAGCAAAGTTTTCAAGAAGTACAGTATCATACGCAAACATATCCGTGCGTTTCACTGCGACCAGAAACACGCATGTCCCCACTGTATTAAAATGTTCCCGACTTTGGATAAATTAAAAATGCATTTATTGCGCCATTCGGACCACCGGGAGTTTTTATGCGCCGATTGTGGCAAGCAGTTCAAGCGCAAAGACAAGCTGAAAGAGCACTGCAAGCGCATGCATTCGGAGGAGCGCGAAAACGACGTTCCAAGGCCCCCGAAACCCGTCTCTCAACCGGTGAAAAAACTCAATCCGAAGAGCGAACCGACCGATTTCCACCGATTCATCTACAAGTGTCACACGTGTCTTGTTGGGTTTAAACGTAGGGGGATGTTGGTTAACCACTTGGCGAAGCGACACCCGGATATAAGCCCGGATTCGGTCCCGGAATTGAATTTACCGATTTTGCAAACGACGCGTGACTATTATTGCCAACACTGCGATAAAGTTTATAAGAGTAGTTCGAAACGCAAAGCTCACATTTTGAAGAATCATCCGGGGGCCGCTTTGCCGATGAGTAACCGGAAACAGGGCAATTTTCCGGATAATTCCGGGCTTCCGAATCCGACGTTTTCGCAAACTGTGGGCAGTATTACGACGCGGCCGCAGAACTGCAAGTGGTGTCATAAGCAGTATGCGAGCAAAGCGAAGTTGTTGCAGCATCAGAGGAAGAAGCACAGCGAGCAGTTGGCTCAGCAGAATGGGGGCAAGGAGGAGCAGAAGTACACGCCGCCGGAGCAGGCGGAGGGACAACAGAATGACTTGCAGGACTTTAAGGTGTCTGAGAGCGATATTTTGAACAGCGCCCTCGAAGAATATAACAAACGCGGAGGGGAGCAGTTTTGTCATTTTGTTGCGATTGAAGGTGGGGACGAGTTTGAGCAGTCAACTGGGGATTTGGGGGCCCCCAATTCGCATTTGTTTCGCTTACTGACAACGAGCAACGAACTTCCAGGTTTAGTGCCACCACGTTGA
Protein Sequence: MDTIVQGPPGEGAQDLNLVDAAWSTQNSQEIVNNNSILYIAVEYIKDEYKMESAVNLPPPENFADFEQHVSPLDPNMSSVARYSPVYSEPTTEYNPVVIHHLVQPNSSQSDINNLAPEPMPVLCNNDIREVVDNHFLQMVNSGNQLQVVPPNEQEVALLITDQETGISYSVRGQEFLVEDEQLLNALSPDPLLDPHLLALDENALKTELGDEIINSTVNTAVNNYITSLSAAVDNDGQYKMETRRQKQNEVEFEDQLLSKVYSIVDKPVPSRARATLPESYLTLSKVDQALGVFAKKTIPRSTQFGPLTGILKPSTERLKNGPTSLQFFIEDENNVVSQIDVSDENASNWMRFIRQATNYNEQNLLITQEGNSLYFTTTRSILPKQELKVGYSVPYATRHKLSILVPEEEKSWPCYECSETFASSDELQKHLNIHDSDEENKWKKKNLKNKKKIPKSETFQCNNCNELFVQPGKVALRQHLIEKHLLSGLDLIDQYFSSVMNYKCDKCELVFNSEPLLKIHNYLHDSDSSDEQTNHVCPNCQKKFPTQRQLVTHVATHALTKKPETETFKCPVCHKMFAMRERLRRHMLVHGSDDSKPLQCKTCNKRFVNNSALAGHIKTHLVGKKIFECPICKENFDHVLKLKLHVPKHCENNTYSCPHCSKVFKKYSIIRKHIRAFHCDQKHACPHCIKMFPTLDKLKMHLLRHSDHREFLCADCGKQFKRKDKLKEHCKRMHSEERENDVPRPPKPVSQPVKKLNPKSEPTDFHRFIYKCHTCLVGFKRRGMLVNHLAKRHPDISPDSVPELNLPILQTTRDYYCQHCDKVYKSSSKRKAHILKNHPGAALPMSNRKQGNFPDNSGLPNPTFSQTVGSITTRPQNCKWCHKQYASKAKLLQHQRKKHSEQLAQQNGGKEEQKYTPPEQAEGQQNDLQDFKVSESDILNSALEEYNKRGGEQFCHFVAIEGGDEFEQSTGDLGAPNSHLFRLLTTSNELPGLVPPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01481136; iTF_01410224; iTF_00415347; iTF_00753226;
90% Identity: iTF_01481136;
80% Identity: -