Basic Information

Insect: Tribolium madens
Gene Symbol: prdm10
Assembly: GCA_015345945.1
Location: JADDYM010000019.1:4229416-4235893[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 3.8e-06 0.00026 21.2 0.1 2 23 419 440 418 440 0.96

2 13 0.71 48 4.7 0.1 1 14 465 478 465 490 0.82

3 13 0.012 0.81 10.2 0.4 1 23 508 530 508 530 0.92

4 13 1.8e-05 0.0012 19.1 1.0 1 23 541 563 541 563 0.97

5 13 4.8e-06 0.00032 20.9 1.8 1 23 574 596 574 596 0.98

6 13 4.1e-06 0.00027 21.2 0.6 2 23 605 626 604 626 0.97

7 13 0.062 4.2 8.0 0.7 1 20 633 652 633 655 0.90

8 13 0.0015 0.1 13.1 2.8 1 23 661 684 661 684 0.96

9 13 0.0032 0.22 12.0 2.2 1 23 689 711 689 711 0.96

10 13 0.0011 0.071 13.6 4.0 1 23 717 740 717 740 0.89

11 13 0.0022 0.15 12.5 1.7 1 23 776 799 776 799 0.97

12 13 0.00017 0.011 16.1 3.9 1 23 821 844 821 844 0.97

13 13 0.0015 0.1 13.1 3.8 3 23 884 905 882 905 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	3.8e-06	0.00026	21.2	0.1	2	23	419	440	418	440	0.96
2	13	0.71	48	4.7	0.1	1	14	465	478	465	490	0.82
3	13	0.012	0.81	10.2	0.4	1	23	508	530	508	530	0.92
4	13	1.8e-05	0.0012	19.1	1.0	1	23	541	563	541	563	0.97
5	13	4.8e-06	0.00032	20.9	1.8	1	23	574	596	574	596	0.98
6	13	4.1e-06	0.00027	21.2	0.6	2	23	605	626	604	626	0.97
7	13	0.062	4.2	8.0	0.7	1	20	633	652	633	655	0.90
8	13	0.0015	0.1	13.1	2.8	1	23	661	684	661	684	0.96
9	13	0.0032	0.22	12.0	2.2	1	23	689	711	689	711	0.96
10	13	0.0011	0.071	13.6	4.0	1	23	717	740	717	740	0.89
11	13	0.0022	0.15	12.5	1.7	1	23	776	799	776	799	0.97
12	13	0.00017	0.011	16.1	3.9	1	23	821	844	821	844	0.97
13	13	0.0015	0.1	13.1	3.8	3	23	884	905	882	905	0.96

Sequence Information

Coding Sequence: ATGGATACGATTGTACAAGGGCCCCCCGGGGAAGGGGCCCAAGACTTGAATCTAGTCGACGCGACTTGGACCACCCAAAATTCCCAAGAAATTGTAAACAACAACTCGATCCTCTACATCGCCGTCGAGTACATCAAAGATGAGTACAAAATGGAGCCCGCGGTTAACCTACCGCAGCCCTCGGAGAGTTTCACCGATTTTGAGCAACACGTGAGCCCCCTTGACCCGAATATGAGTTCAGTGGCGCGGTACAGCCCTGTGTATAGCGAGCCCACCCCTGAGTACAACCCTGTGGTCATCCACCATCTGGTACAGTCGAATTCCGGCCAAAGCGACATTAATAATTTGGCCCCTAATGCGGCCCTGGAGACCATGCCGGTGTTGTGCAATAACGACATAAGAGAAGTGGTAGACAACCATTTCTTGCAAATGGTCAATTCCAATAACCAGCTCCAAGTGGGCCCCCCCAACGAGCAGGAAGTGGCACTTCTGATAACTGACCAAGAAACCGGGATTTCCTACAGTGTCAGGGGGCAAGAATTTCTCGTCGAAGACGAACAGTTGTTAAATGCGTTGAGTCCGGACCCGCTTTTGGACCCCCATCTTTTGACACTGGACGAAAATGCGCTTAAGACCGAACTAGGGGACGAAATAATAAACTCAACAGTAAACTCCGCCGTTAATAATTATATCACGAGTTTGAGCGCTGCGGTAGACAGCGACGGACAGTACAAGATGGAGACCAGGAGGCAGAAACAGAACGAGGTCGAGTTTGAAGATCAGTTATTGTCCAAGGTTTATAGTATTGTGGACAAACCGGTGCCGTCGAGGGCCAGGGCCACGCTTCCAGAGTCCTATTTGAGTCTGCTTAAGGTGGACCAAGCAATCGGCGTTTTTGCCAAGAAAACAATCCCTAGAAGTACACAATTCGGACCTTTGACTGGAGTTTTGAAACCAAGCACCGAACGTTTGAAAAATAGTCCAACTTCTTTGCAATTTTTCATAGAAGATGAAAACAACGTCTTGTCACAAATTGATGTTTCAGATGAAAATGCCTCAAACTGGATGCGTTTTATAAGACAAGCGACGAATTTTAACGAACAGAATTTGTTGATAACTCAAGAGGGCAACTGTTTGTATTTCACAACAACGAGGAGTATTCTTCCGAAACAGGAATTGAAGGTTGGCTACAGTGTGCCCTACGCCACCCGTCACAAATTATCAATTCTCGTCCCGGAAGAAGAAAAATCCTGGCCTTGTTACGAATGTCCCGAGACATTTTCCTCCTCTGATGAGTTACAAAAACATTTGAACGTGCACGACAGCGATGAGGAAACCAAATGGAAGAAAAAGAACCTAAAAAACAAGAAAAAAATCCCCAAAAGCGAAACCTTCCAATGCAACAACTGTAACGAATTGTTTGTCCAACCGGGAAAAGTCGCCCTCAGACAACACTTGATTGAAAAACACCTTTTGAGCGGTTTGGATTTAATCGATCAGTATTTTTCATCAGTCATGAATTACAAATGTGATAATTGCGAATCGGTTTTCAACTCGGAAGCTTTGCTAAAAATCCACAATTATCTTCACGATTCGGACAGTTCAGACGAACAAACGAATCACGTGTGTCCCAACTGTCAGAAAAAATTCCCAACTCAACGCCAACTTGTCACGCATGTCGCCACACACGCCCTCACCAAGAAACCGGAAACGGAAACGTTCAAGTGTCCGGTGTGTCACAAAATGTTTGCGATGCGTGAGCGACTTAGACGCCACATGCTGGTCCACGGCTCGGACGACTCAAAGCCTCTCCAATGTAAAACTTGCAATAAACGCTTTGTGAACAATTCGGCCCTCGCTGGCCACATCAAGACCCACCTTGTCGGTAAAAAAATCTTCGAGTGTCCCATTTGTAAAGAAAATTTCGATCATGTATTAAAACTGAAACTCCACGTACCGAAACATTGCGAAAACAACACCTATTCGTGCCCCCATTGTAGTAAAGTCTTCAAGAAGTATAGTATTATAAGGAAGCATATTCGGGCGTTTCATTGCGATCAGAAACACGCGTGCCCCCATTGTATTAAAATGTTCCCGACTTTGGATAAGTTGAAAATGCATCTTTTGCGCCATTCGGACCATCGAGAGTTTTTGTGTGCCGATTGTGGCAAGCAATTTAAGCGCAAAGACAAGTTGAAGGAGCACTGCAAGAGGATGCATTCGGAAGAGCGGGAAAATGACGTCCCGAGGCCCCCCAAACCTGTCTCGCAGCCGGTGAAAAAAATCAATCCGAAGAGTGAACCCACCGATTTCCACCGTTTCATCTACAAGTGTCACACTTGTCTTGTCGGGTTTAAACGTCGAGGCATGTTGGTGAACCACTTGGCGAAGAGACACCCGGATATAAGCCCGGATTCGGTCCCGGAATTGAATTTACCGATTTTGCAAACGACACGTGACTATTATTGTCAACATTGCGATAAAGTGTATAAGAGTAGCTCGAAACGCAAAGCGCATATTTTGAAAAATCATCCGGGGGCCGCTTTGCCGATGAGTAACCGGAAACAGGGGAATTTTCCGGATAGTTCCGGGCTTCCGAATCCGACATTTTCACAAACGGTGGGGAGTATTACCACAAGGCCGCAGAATTGCAAGTGGTGTCATAAACAGTATGCGAGCAAAGCGAAATTGTTGCAACATCAGAGGAAAAAACATAGCGAGCAGTTGGCTCAGCAGAATGGGGGCAAGGAGGAGCAGAAGTATACGCCCCCGGAGCAGGGGGAGGGGCAGCAGAGCGACTTGCAAGAGTTTAAGGTGTCTGAGAGCGACATTTTGAACAGCGCCCTCGAGGAGTACAACAAGCGCGGAGGGGAGCAGTTTTGCCATTTTGTGGCGATCGGCGGTGGGGACGAGTTTGAACAGCCGGGGGACTTGGGGGCCCCCAATTCGCATTTGTATCGTTTACTGACAACGAGTAACGAACTTCCAGGTTTAGTGCCGCCACGTTGA
Protein Sequence: MDTIVQGPPGEGAQDLNLVDATWTTQNSQEIVNNNSILYIAVEYIKDEYKMEPAVNLPQPSESFTDFEQHVSPLDPNMSSVARYSPVYSEPTPEYNPVVIHHLVQSNSGQSDINNLAPNAALETMPVLCNNDIREVVDNHFLQMVNSNNQLQVGPPNEQEVALLITDQETGISYSVRGQEFLVEDEQLLNALSPDPLLDPHLLTLDENALKTELGDEIINSTVNSAVNNYITSLSAAVDSDGQYKMETRRQKQNEVEFEDQLLSKVYSIVDKPVPSRARATLPESYLSLLKVDQAIGVFAKKTIPRSTQFGPLTGVLKPSTERLKNSPTSLQFFIEDENNVLSQIDVSDENASNWMRFIRQATNFNEQNLLITQEGNCLYFTTTRSILPKQELKVGYSVPYATRHKLSILVPEEEKSWPCYECPETFSSSDELQKHLNVHDSDEETKWKKKNLKNKKKIPKSETFQCNNCNELFVQPGKVALRQHLIEKHLLSGLDLIDQYFSSVMNYKCDNCESVFNSEALLKIHNYLHDSDSSDEQTNHVCPNCQKKFPTQRQLVTHVATHALTKKPETETFKCPVCHKMFAMRERLRRHMLVHGSDDSKPLQCKTCNKRFVNNSALAGHIKTHLVGKKIFECPICKENFDHVLKLKLHVPKHCENNTYSCPHCSKVFKKYSIIRKHIRAFHCDQKHACPHCIKMFPTLDKLKMHLLRHSDHREFLCADCGKQFKRKDKLKEHCKRMHSEERENDVPRPPKPVSQPVKKINPKSEPTDFHRFIYKCHTCLVGFKRRGMLVNHLAKRHPDISPDSVPELNLPILQTTRDYYCQHCDKVYKSSSKRKAHILKNHPGAALPMSNRKQGNFPDSSGLPNPTFSQTVGSITTRPQNCKWCHKQYASKAKLLQHQRKKHSEQLAQQNGGKEEQKYTPPEQGEGQQSDLQEFKVSESDILNSALEEYNKRGGEQFCHFVAIGGGDEFEQPGDLGAPNSHLYRLLTTSNELPGLVPPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01480343;
90% Identity: iTF_01480343;
80% Identity: -