Basic Information

Gene Symbol
-
Assembly
GCA_001594075.1
Location
NW:3771974-3783793[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 32 5.5e-06 0.00038 20.2 1.0 1 23 253 275 253 275 0.98
2 32 0.0079 0.55 10.3 3.7 1 23 298 321 298 321 0.96
3 32 0.00053 0.037 13.9 0.5 2 23 328 350 327 350 0.96
4 32 0.00093 0.064 13.2 0.1 1 21 370 390 370 391 0.95
5 32 0.011 0.76 9.8 0.1 2 23 489 510 488 510 0.95
6 32 0.0054 0.37 10.8 0.2 1 23 516 539 516 539 0.91
7 32 0.00016 0.011 15.6 0.2 1 23 610 633 610 633 0.96
8 32 0.059 4.1 7.5 3.1 1 23 639 662 639 662 0.95
9 32 0.11 7.3 6.7 1.5 1 23 675 697 675 697 0.97
10 32 3e-05 0.0021 17.9 0.9 3 23 742 763 741 763 0.96
11 32 2.6 1.8e+02 2.4 0.4 1 23 795 818 795 818 0.92
12 32 0.0046 0.32 11.0 1.0 2 23 825 848 824 848 0.94
13 32 0.78 54 4.0 0.0 2 23 857 879 857 879 0.90
14 32 0.023 1.6 8.8 0.0 2 23 886 908 885 908 0.93
15 32 7.8e-05 0.0054 16.6 3.2 1 23 916 938 916 938 0.97
16 32 0.03 2.1 8.4 1.3 3 23 976 998 974 998 0.93
17 32 0.00018 0.013 15.4 3.3 1 23 1001 1024 1001 1024 0.97
18 32 0.0006 0.042 13.8 0.1 2 23 1031 1053 1030 1053 0.96
19 32 0.0008 0.055 13.4 3.9 1 21 1080 1100 1080 1101 0.95
20 32 0.0023 0.16 11.9 1.8 2 23 1115 1136 1114 1137 0.93
21 32 0.33 23 5.2 1.1 1 23 1140 1163 1140 1163 0.94
22 32 0.023 1.6 8.8 2.1 2 23 1170 1193 1169 1193 0.90
23 32 2.1 1.5e+02 2.6 0.1 2 23 1201 1223 1200 1223 0.94
24 32 2.8 2e+02 2.2 0.0 2 23 1230 1252 1229 1252 0.88
25 32 0.2 14 5.9 2.7 2 23 1261 1283 1261 1283 0.96
26 32 0.6 42 4.3 0.5 2 23 1289 1311 1288 1311 0.91
27 32 0.015 1 9.4 0.1 1 23 1373 1396 1373 1396 0.95
28 32 0.00015 0.01 15.7 1.1 1 21 1424 1444 1424 1445 0.95
29 32 0.28 19 5.4 1.9 2 23 1546 1568 1545 1568 0.94
30 32 0.8 55 3.9 0.4 2 23 1575 1597 1574 1597 0.94
31 32 0.61 42 4.3 2.5 1 23 1608 1630 1608 1630 0.97
32 32 0.069 4.8 7.3 0.2 1 19 1634 1652 1634 1655 0.93

Sequence Information

Coding Sequence
ATGGCGACGATATCGACGATCACGACGACAACGTCGATGTCGACGTCAACGACGAGGATCGAGACAGCGATGGCGACGGAGCCGAGAAGGAACTATAACGAACTGTGTCGCTTATGCGCTTCCTACGACGCCGTTAGGATGCACATATTTGGCCAGGAAGGCAAGAATCGTCAACTCGTCGACAAGATTGAAACGTGCTTGCCGTTCAAGATAATGGAAGATGATTATTTGCCAAAAGTCCTGTGTTATCGATGTATGTACAACTTGGAGAATTTCTATGACTTTAGGACTGCGTGTGTTAACGCAGCTGTTTTGTTGGAAAGAAATAGGCCGAAGGAAGGCGTGAGCGATGAAGATGCAAATGATACTGCGCAATCCTGCGAGATGCGCGCGGCGTTtcttaagaaagaaaatatgccAGTACTTATCCCGGAAGCACCCGTAGTCAATCCCAATGCAGCATTGGGTACGCCACCGAGATTAAATTCGGATGGTGAAGCAGATCCCGAGATCGAAGAGATTCTTGACACAAGTGAAGGTACGGACGAAGcCACAGTGATCGACGATTCGGAAGATCGGCGATCGGAATATGAGATGGCATACGAAATGGATATGGAGACGAATCCTAGCGACTTCTTGGAAATGACCCCGATGGTAACCGAAGAAAATGAAGAGGAATGTAGTACAAACAACACGAATGCCACGACTGCTCAAGATACCACGGTCTTTCCACATACGTCACAACAACATGAGGTCTACGTCTGTTCTCTATGCAACAAAGCGTTCAGTTCCAAGGGTCACTTGTCTCTGCACGCGAGGATTCACGTGGGTGAGGGTGATGTGATTGGCGAAAGAGTAATTACCGACGACCATACTTCGTACCAACGACCGTATCAATGTGATCTTTGTCATAAATCGTATTCTACTGCGAAGCATCGCTGGGGGCACGTTTCTACAACGCATCGGGGACATCCTGCAGTAACGTGTGCGTACTGTTCTCGTATATACTCGACGCGATATAATCTCGATGAACATATAAAATCACGACATGCTGGGCTACCACCACCCCCAGAATTATCGGTTCCCCTAACGCGTACGGAAACACGTTACCAGTGCCAAACATGTCCGATGGCGTTTACGGATCTAGCAGATTTCAATGCGCATCGTCAGATATGCATCCAGGAACAACGTACAGATTTATTAGGTCAAACCGAAGcgcagaataataaaattttcgccGATACATCCGACGTCTCGAGTATAGATTTGGATGACGAGAATAAAGACTTTAAGAATGCCGAGGCTAAATTGGCGAAAAATCCACAGTTAACCATATTGAAACAGGCGCTGACTAAAGGAGACAATTTAAAACGGAATTTCGATGATGATGGTTCGACGTCTAGCGGCAAGCCGAAAAAAATAGTTAAGTCAgAAGAAGGCGAGGCAAATCCTCAGAAGAGATGGTATTGTGAAGCTTGTCCACAAAGTTTTACATCAGTGGAGAGTTTAAAAGAACACGAGATTAGACATGATGCCGAAAAGCCATATATTTGCATACTATGCAACAAAGATTTTGTTTTGAAATCTTCATTAATTAGGCATATTACAGTGTTACATGGTGTTGATCCTACTCCTATCATCGACAGTGATAAGTGTCTAAAGGCAACAGTAATGTCTCAGAATTGGAACGATCGAGTGGACGTCAGCGTTTATGAGCAAAGTGAAATAAAAGACCCACTAGAGCTCTCGTCGTCACCTgagataaatttagaGAATGATGACAAGGATTATAAAAACAACcatgaaaatgtagaaattgaAACGGTATTTGTGTGTGAGACATGTAAGCGAGATTTTAACGATCGAGCATCATTATGGCTGCATATACGAGCAATGCACAAGGAATATGCAGCATTTACCTGTGGAGTGTGTTTAAAGATGTGCTTTAATAATACACAACTTCAAAATCATGTCTTCATGTATCACGGAAAGTCTAAGCTTTTAATCTCGGAACAAAGAAgGTATAGTTGCACGATATGCGGTAGACAGCATGACTCGAGAAAAAAGCTAATCACTCATGTCTCTATACATAATGTCGATCCTGCCTATGATCCTGGAAGTTTTGTACAGTTGAacagtaattattataatgaaaactTGAATGGTAACGAAGGCAATGAACAAGTATTAGATTTTGACGGAGAAGATGGCGAGAAGGTTGATTGTTACATTTGTTATAAATCTTTTCCGACTGAGGATCATCTTATACGACATCAGAGAAATGCTCACAagTCTGACCAGATTTCGTTAGGAGATGCTGCGGGTGGTGGAAATACTCTAAGTGTCAATGGCAATGGTAATAGAGCGCAGTatcatttgttttttgtttGCGAGGTATGTGGTAGTTCACATTCGAGCAAATGGGAACGTTGGTTGCATATCAACAACACACATAACAATGAATCTTCTATTAAATGTGAATTGGAAAATTGCGGAAAGATATTTGCGACGAAATCGTTACGTAATGAACATCTTCAGCATCATGCGATACAAGGACCTTCGCCAAACACCTGCGAAATATGTGGAAAATTGTGGCCTACTCGCGTTGATTATTGGAAACACGTGATGGGCGTACATGCGGACACAGTGCCTCTAATTTGTGGCGTTTGTTTGAAAGTATTCTCCGACGTTATGCAATTGAGCGCACACGTTAAGGCGAAACATTGGCCACTAACCAGTGGTGATTTCTGTTGTGATATTTGCGGTAGACCATATTCCAATAAATCGAAAATGTCTCGGCATAGAAAGATTCATGGCTTGGAGGCGGCTATGGACGCTGCATGCGATAATAGCAGTTTTAATGAAACTACCAATGAATCGGTGAAACCTGATCACAGTAATGGCGCTtcagaaatagaattaaattgcGAGCAGTGTCCTGAACTTAGTTTCACGACATTGGACAGTTTGTGTAATCATCGACGGATAACGCACAATCTTTTCCCGTGCGATTTGTGTAACAAATGTTATGGCAGAACGTCACATTTATGGAAACATGTAAATAGGGTGCACAAAGGACACACAGACGTGACCTGTCCTTACTGCGCAAAGACAAGCGCGTCAAGGGATCATCTGGCAGCACATATTGCAAAGATTCATAGGTTCATGCCCACAGTGGGTAAGGACAATCAAAATTGCGTTACTTCCAAGTCCTTGAGTGCAGACGACGGTGTCTTGcattattgcgaaaaatgtaACAAGGGATTCCATAAACGCTACTTGCTCCGTCGTCATATGAAAGGCTGTCAAAACTATCGTAAAGATCCTGGGGCATTGTTAACCCGTTGCCGGGCCTGCGAGAGGATATTTAAAGATCGTGCGAGTCTGCAGAAACATATTGAGAATCATCATACTACATATACTTGCCATTTGTGTAATGAGACGATCACTTCCAAGCTAGGTATCATGACACACAATCGTATCAATCATATGGATCATCCGGATCTGACGTGCGACCACCCGAGCTGTAAAAAACTTTTCCGCACCAAAGAAGATTTGGAATCTCATCGAAAAGATCACAAATATCATAGCAACCTGGACGTTTGTGATTTTTGCGGTGACACCGTGGAAAATAAACTGAAACTGAAGATGCATGTATTATCGTTGCATCGAAACGAAATCGGCGTATCCTGTGGGGTCTGTCTCATTCCAATGAAGGATCCTAAAGATTTGAAGAAACACGTCGAAGCGGTGCATAGCAGCGTTCTCTCTAAACCAAACACGTGTCAGGTATGTGGCAAGCAATATGCATCCAAATGGAAGGCTTTTGACCACACGAAGAAGTGTCATGGCAAAGTTTTTCTCACATGCAAACAGTGTTTAGCCGTTTTTACAGACGAGAATGATATACGCGATCACTATGAACATGTGCATAACGTTTCAAAGGACCAATTAGCTATTTTCGAATATAGAATGGATATTGGTGCAAAGAGGGAGGGTTACGAGACTCCTGATATCATTGTGAAGGAGGAACCAGATGATTTAGAGTTTGACGAAGAAATGTGTGACGAAAGTTCGAATGATTCTCGCAAACGTAGAAGATCGCCAAACGATACGTATGATTGCGAGATGTGTCCCGAGATCTTCCTCAATTCAGACACTCTCGCCAAGCATTATCAGAACGTCCATAATACAGACCCCGTCCGTATGTTCAAGAAATTCAGAAAGGATAATAGCGATGGCAAGCGCAAGATGAGAAATAGAAACAACTTTGAATGCAAGAATTGCAAAAAGCAATTCTCTACTAAGACTCTGTTTTGGAATCACATCAATGTATGTACACGACGAAACTCGGTAGGTAGATTTGACGTGCCGAATAATGTGCCGACATCAATTCTGGAGTCTCATCTGAAAAACAATAATCAGATTCAACGAGAAGAACCGGTACCGCTTACGAACGAGTCCAACTTGAACATTCCCGACTTCAATCTATTCGAAGACATCAATTTGCAATTGTCAGCTCAGAAACCTGTGCCGAATCTTATGCCATTGTCGCAGATGAAAGCGACGGGTAACGGCAAATGCTCGAGAAAAGACTCACGCAAGGTATATGATGAATCGACTAATACAGAGTGTACGTGCGAAGTTTGTGGTAAACAATGGCCCGCCAAGAAACATTTGTGGCAACATCTAATTCGTTTTCATCGCGCCGAAGCTGCTGTTACGTGTGGCGTATGTTTGAAGCTGTGTAAATCTTACCAAGACTTAGCCGACCACCTGAAGGCTGAACATGCCCCCGTTTTGTCGCCGGAGGGCAATAATTTCACATGTAAGACGTGCGGTAGATATCATAACGCTAGAAGCAAATTGCTGCTGCACATGAGCATCCATATCGGAAACTTCCGGTGTCAAAAGTGCCAGCAAGGTTTTGCAAGTGACGAGAAACTCACCGAGCATGCAACGAGCTGCAATGGAAAATTGGAGTTTGAGGATAATACAGTGGCAGATGAAGATAATGCAAAGAATGACAATGACGAGAAGGGCAGTTTAATCGCCGACGAGACATCAGTCATTGAGGAAGCAGAGGAAGCGGAGGAAGCAGATTTTGAATCAGAAGGTGAAGGAAGTAGGGATATTCACGATGAAGATAATTCGGAAAATAGCGAAGAAGACAATTCGGAAAATAGTGATGATTCAGACAGCGATAGTAATAGTAGTTCGAGCGAAGACGAAAACGAAAATGAaggagaggaagaggaggaggaagaggaagagaatGAAAACGAAAATGAATCTGATACGAGAACTACTAGTAGAGCGAGCGGTGATAGTGTATCATGTAATTCCGATAGCGACGATGAATCAGATATGGATGAAACGGAAGTGGACGCAACGGAAAAGAAAGCTGTACAATTGAACGATATTAATAGATTCAGGATATGTGGTGACGGTATTCAAGAGAATATGCCATTGGAGACAAATATCGAGGATCAGAAAACCGATCTTACATCCATAGCAACGATTGCAGAACAGACTCCATCAAATAATTTAAGTGATCTTTTGATTTCTAATGTATCTGGAAACATGAGCACCGACAAATTTGAGGCATTTCATATCGAAAAACTACAACAAATTAAAGCTACAACGAGTGATGTAGACTCTGATAACGAAGACGATGATGATAACGAGGAAGATGATgaggaaaataatgaaaatgaagaagaggaagaagatgGTGAAGAAGGTGATCAGGATGAAGGTGAAGATGAGGATGAAGGTGAGGCTGAGAGTGAGGCTGAAAGTGAGAATGAGAATGAGGGTGAGGGTGAGGGTGAGGGTGAAGGTGAAGCTGAAGCTGCAGccgaggaagaggaggaagaagaggaagaagaagaggatgAAGACGATGATGGACCGCCCGTGTTAAGTCCAATAATGCCTTTGTTACCAGAAAACGAATCTGAGGAGTACAGCGGTACGACAGATCGCACGAGGCACAAGCTTAGTCCAATGGTTTCGCTGAGTATAGCTAAAGATCTAGAGGAGTGCGAAATAACCGAAATACCAAATGATACTGACAATGTGTCAAACACAGTCAACTTCTTCGCggctaataataatgatttaccCGTAACATGGGACGAGAATTTGGATGGTAATGTAATCAACAATGGCGATTGCAACTCCGACGCTGGAAACAGGGAGAAAAATGAGGAATTTGATACGGAGTACGTAAAAATAGAAGTAAACGAAGGCGACTTCGAGGAAGATTCCGTGGATGAGAACGTAATGGATAACAGAGAAGATGATGGAGACAATCAAGTGCATGAGGTGCATAATCTGGACGGAACTGTGTTAATGGTGACTAATGATGCGGAAGGTAATCAAATTTTGATAGAACAAAACGTGTTAGATATCGATAACGAGGACTGTAATGTCGAAGAGGCGCAGTATATTTATCCAGAGAACACTTACGAGATCGAGGAAGAGGATTATGCAACGCGAAACGAAACCGACGTCATGCAGACGGACGAGATGCAAGGTAATATGTCCTACGTTCAAGATACATCGGAAAACGAAGATAGTGTGCAGGATGATATCGAGGAGAACAGTGATGTGCAAAAACAGTAG
Protein Sequence
MATISTITTTTSMSTSTTRIETAMATEPRRNYNELCRLCASYDAVRMHIFGQEGKNRQLVDKIETCLPFKIMEDDYLPKVLCYRCMYNLENFYDFRTACVNAAVLLERNRPKEGVSDEDANDTAQSCEMRAAFLKKENMPVLIPEAPVVNPNAALGTPPRLNSDGEADPEIEEILDTSEGTDEATVIDDSEDRRSEYEMAYEMDMETNPSDFLEMTPMVTEENEEECSTNNTNATTAQDTTVFPHTSQQHEVYVCSLCNKAFSSKGHLSLHARIHVGEGDVIGERVITDDHTSYQRPYQCDLCHKSYSTAKHRWGHVSTTHRGHPAVTCAYCSRIYSTRYNLDEHIKSRHAGLPPPPELSVPLTRTETRYQCQTCPMAFTDLADFNAHRQICIQEQRTDLLGQTEAQNNKIFADTSDVSSIDLDDENKDFKNAEAKLAKNPQLTILKQALTKGDNLKRNFDDDGSTSSGKPKKIVKSEEGEANPQKRWYCEACPQSFTSVESLKEHEIRHDAEKPYICILCNKDFVLKSSLIRHITVLHGVDPTPIIDSDKCLKATVMSQNWNDRVDVSVYEQSEIKDPLELSSSPEINLENDDKDYKNNHENVEIETVFVCETCKRDFNDRASLWLHIRAMHKEYAAFTCGVCLKMCFNNTQLQNHVFMYHGKSKLLISEQRRYSCTICGRQHDSRKKLITHVSIHNVDPAYDPGSFVQLNSNYYNENLNGNEGNEQVLDFDGEDGEKVDCYICYKSFPTEDHLIRHQRNAHKSDQISLGDAAGGGNTLSVNGNGNRAQYHLFFVCEVCGSSHSSKWERWLHINNTHNNESSIKCELENCGKIFATKSLRNEHLQHHAIQGPSPNTCEICGKLWPTRVDYWKHVMGVHADTVPLICGVCLKVFSDVMQLSAHVKAKHWPLTSGDFCCDICGRPYSNKSKMSRHRKIHGLEAAMDAACDNSSFNETTNESVKPDHSNGASEIELNCEQCPELSFTTLDSLCNHRRITHNLFPCDLCNKCYGRTSHLWKHVNRVHKGHTDVTCPYCAKTSASRDHLAAHIAKIHRFMPTVGKDNQNCVTSKSLSADDGVLHYCEKCNKGFHKRYLLRRHMKGCQNYRKDPGALLTRCRACERIFKDRASLQKHIENHHTTYTCHLCNETITSKLGIMTHNRINHMDHPDLTCDHPSCKKLFRTKEDLESHRKDHKYHSNLDVCDFCGDTVENKLKLKMHVLSLHRNEIGVSCGVCLIPMKDPKDLKKHVEAVHSSVLSKPNTCQVCGKQYASKWKAFDHTKKCHGKVFLTCKQCLAVFTDENDIRDHYEHVHNVSKDQLAIFEYRMDIGAKREGYETPDIIVKEEPDDLEFDEEMCDESSNDSRKRRRSPNDTYDCEMCPEIFLNSDTLAKHYQNVHNTDPVRMFKKFRKDNSDGKRKMRNRNNFECKNCKKQFSTKTLFWNHINVCTRRNSVGRFDVPNNVPTSILESHLKNNNQIQREEPVPLTNESNLNIPDFNLFEDINLQLSAQKPVPNLMPLSQMKATGNGKCSRKDSRKVYDESTNTECTCEVCGKQWPAKKHLWQHLIRFHRAEAAVTCGVCLKLCKSYQDLADHLKAEHAPVLSPEGNNFTCKTCGRYHNARSKLLLHMSIHIGNFRCQKCQQGFASDEKLTEHATSCNGKLEFEDNTVADEDNAKNDNDEKGSLIADETSVIEEAEEAEEADFESEGEGSRDIHDEDNSENSEEDNSENSDDSDSDSNSSSSEDENENEGEEEEEEEEENENENESDTRTTSRASGDSVSCNSDSDDESDMDETEVDATEKKAVQLNDINRFRICGDGIQENMPLETNIEDQKTDLTSIATIAEQTPSNNLSDLLISNVSGNMSTDKFEAFHIEKLQQIKATTSDVDSDNEDDDDNEEDDEENNENEEEEEDGEEGDQDEGEDEDEGEAESEAESENENEGEGEGEGEGEAEAAAEEEEEEEEEEEDEDDDGPPVLSPIMPLLPENESEEYSGTTDRTRHKLSPMVSLSIAKDLEECEITEIPNDTDNVSNTVNFFAANNNDLPVTWDENLDGNVINNGDCNSDAGNREKNEEFDTEYVKIEVNEGDFEEDSVDENVMDNREDDGDNQVHEVHNLDGTVLMVTNDAEGNQILIEQNVLDIDNEDCNVEEAQYIYPENTYEIEEEDYATRNETDVMQTDEMQGNMSYVQDTSENEDSVQDDIEENSDVQKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00015543;
80% Identity
-