Ttro001282.5


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trachelus troglodyta
Gene Symbol
foxp1
Assembly
GCA_030142635.1
Location
JARQTJ010000076.1:10119-28060[-]

Transcription Factor Domain

TF Family
Fork_head
Domain
Fork_head domain
PFAM
PF00250
TF Group
Helix-turn-helix
Description
The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.9 7.4e+02 0.5 0.6 21 54 183 216 175 234 0.84
2 3 1.7e-29 1.4e-26 92.5 0.3 2 81 612 685 611 693 0.94
3 3 8.9e-06 0.0073 16.5 0.0 48 82 702 731 688 736 0.85

Sequence Information

Coding Sequence
ATGCCCGAAATTACTCTCTCCGATGCACCCTCTATTCTCCTGGTGTGTTCTACCCTCTTGCCGAGGGTAGTCAGCACACTTTTCGCAGCGttgaagcagcagcagcagcagcagcaacaacagcatcTTCAGTCAAGGGACTCGTCCCACAACAGAGAAAGAGTGATAACGCGTGGGCGCGAGAGGGTCAGCAGCAACAGCACAGCCAGTGGAGCCGACGGGGAGCAGCAACAAGAGCTCACCATCGAGTACCAAGGCAATGGGAAGCTCAGTCCTACTGGGCACTCACTGACATCTGCACCGATGACCCAGCAAAAGCAGCCATTCATCACGCAACAGTCCCAGCAGCCGAGTTCCGGGGCCCCCGGGCCCCAACCAAGTCCTCATCAGAGTCCTCAGGCACCCCAAAGGGGCTCACCGCCAAATCCTACGCAGGGCCCGCCCCCAGGAGGCCCCCCAGGGGGTGGTCCACCCTCGCAGACAACGTCGCAGATGATGCTCAGCCCGGCGAGTGGCTTGCATCAGATGCAGCAACTTCTACAGCAGCACATTCTCAGTCCAAGTCAGCTGCAGTCATTCATGCAGCAACATACGTTGTACttgcaacagcagcagcagcagcatcaccAGGACTCCTCAGAACATGCGGCTAACCAGGAACGATTCGGTTACTTTTCATCTCTGAAAAACCACCAACATCAACTGGCTGAACTCGGCCGCAAGCAGCTCGAGCAAGCTATGCAGCAGCTGCAGGAACAGCTGCAGCTCAACCTGATCCAACAGACGCATCTACTGCAGACAGCCGACAAGAAGAAAGCCTCGGCGCCGCTCCAGCAACTTGCGCTCCAGCAACAGCAATTGATACAGCAGCTTCAGATCACCCAGAGGCAGTATCTACTTCAGCAAGGCTTGGGTCTCCAGGGTCACAATCACTCCTCAGGCCTCCAGCCAGGGGACTCTTTGCCGGCATGGAAGACGGCGGCGGACGCCTCGGACGGTACAGAAACGCACCAGAATTCGAACGCGCTGAAATCCTCGACAGGATTGAACGGTATTTTAAATTCGATAGTTTCCGGCCGACGGACGGAAATGAATGGCGGCTCCGGCTTGGATGAGAAACCACTGGATGTCTCCTGCAACGATAAGGCTCATCCGCTCTACGGCCACGGAGTTTGCAAGTGGCCCGGCTGTGAAGTTATTTGCGATGACTATCAAGCATTCCTCAAGCACCTCAATACCGAACACACCCTGGACGACAGATCGACAGCACAGGCTAGAGTGCAGATGCAGGTTGTCTCGCAGTTGGAAATACAGTTGCAGAAAGAACGCGACCGGCTGACTGCAATGATGCACCATCTTCACGTGGCCAAGCAAATGGCCTCGCCCGAACCGCCAAAATCCTCGGAATCTTCGacGGGATCGAGTTTACCGAAGCTGAATCTCTCCTCGGCCTTGATGAGCCAACCACCATCGAACTTTGGCGTTTCCCAGGTCTCGCCAGTCTCGATGTCGGCCCTCGTTTCTGCCGTGAGGTCACCGGCGGGAGGACAACTTCCGCCATCAGCGGGTGGTGCCCCGATGCCGCCGATACCGAACCTCTCGAACATGTCAGGCATACCACCGATGCCAAACATGCCCGGCAGCATGCCGAGTATGCCGAGTATGCCGAATATGCCAAGTATGCCCAGTATGGCTGGACCCATAAGAAGGCGAATCAGCGATAAATCGGCACTCTCTCTGGCTGGAGGGCTGCCCTACATGCTGGAGCGTGCTGGTCTTGACGTCCAACAAGAGATACAACGGAATCGGGAATTTTACAAGAATGCTGATGTGCGGCCACCCTTCACATACGCTTCATTAATTCGACAGTCGATAATCGAGTCGCCGGATAAGCAACTGACGTTGAACGAAATCTACAACTGGTTCCAGAATACATTCTGCTACTTCAGACGTAACGCAGCCACGTGGAAGaaCGCAGTGCGACACAACCTGTCTCTCCACAAATGTTTCATGCGAGTTGAAAACGTGAAAGGGGCCGTTTGGACGGTGGACGAAGTGGAGTTTTACAAGAGACGTCCTCAACGCGCTTGCAGCACGACTGGGTACAACGCGATCCGCACCAATCTATCATTGCACAAGTGTTTTGTGCGCTATGAGGACGACTTCGGGTCATTCTGGATGGTGGACGACGCCGAGTTTGTAAAGCGGCGGCATCTATCCCGCGGCCGCCCCAGGAAATATGACCCAACCCCATCACCCACTCCACCCCACCTCTCCGCACAGGGTGTCCCGTCCAAGAGCCCCACGCTAACCCACAGTCCAACGATGTATGGGGATGCATTGAACAGCAACCTCCAGTATTTCCAGGCTGCGCTCGGTGAGTCGAACATGGGCTTTCTGAACAACTCGATGTGCACGTCGACAGCGACAAGTCCTGACAAGGAGCACGTGATGGCCCACAGCGATCTGATGTCACCTTTGGATGAACCGGCGGTGCATATAAAGCAAGAGGGTCAGAGTCCCGAGGGAGGCAAGCTGTCCAGACTAATAAAGCGTGAACTCCTGGATGCACCTACGGAACAGGAGCAGGAGGAGGACCAGGTTGACGAGAGGGATTACCCGGAAAGTCACGGGCATGATTCCGGTCAAGACGAAGATATGGCCGAGGACCTCTCGATGGCACCCGACATCATGACGCCGGATGATCAGATCGAGGCGTAG
Protein Sequence
MPEITLSDAPSILLVCSTLLPRVVSTLFAALKQQQQQQQQQHLQSRDSSHNRERVITRGRERVSSNSTASGADGEQQQELTIEYQGNGKLSPTGHSLTSAPMTQQKQPFITQQSQQPSSGAPGPQPSPHQSPQAPQRGSPPNPTQGPPPGGPPGGGPPSQTTSQMMLSPASGLHQMQQLLQQHILSPSQLQSFMQQHTLYLQQQQQQHHQDSSEHAANQERFGYFSSLKNHQHQLAELGRKQLEQAMQQLQEQLQLNLIQQTHLLQTADKKKASAPLQQLALQQQQLIQQLQITQRQYLLQQGLGLQGHNHSSGLQPGDSLPAWKTAADASDGTETHQNSNALKSSTGLNGILNSIVSGRRTEMNGGSGLDEKPLDVSCNDKAHPLYGHGVCKWPGCEVICDDYQAFLKHLNTEHTLDDRSTAQARVQMQVVSQLEIQLQKERDRLTAMMHHLHVAKQMASPEPPKSSESSTGSSLPKLNLSSALMSQPPSNFGVSQVSPVSMSALVSAVRSPAGGQLPPSAGGAPMPPIPNLSNMSGIPPMPNMPGSMPSMPSMPNMPSMPSMAGPIRRRISDKSALSLAGGLPYMLERAGLDVQQEIQRNREFYKNADVRPPFTYASLIRQSIIESPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAVRHNLSLHKCFMRVENVKGAVWTVDEVEFYKRRPQRACSTTGYNAIRTNLSLHKCFVRYEDDFGSFWMVDDAEFVKRRHLSRGRPRKYDPTPSPTPPHLSAQGVPSKSPTLTHSPTMYGDALNSNLQYFQAALGESNMGFLNNSMCTSTATSPDKEHVMAHSDLMSPLDEPAVHIKQEGQSPEGGKLSRLIKRELLDAPTEQEQEEDQVDERDYPESHGHDSGQDEDMAEDLSMAPDIMTPDDQIEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01411297;
90% Identity
iTF_01130626; iTF_01474498; iTF_00253379; iTF_01473732; iTF_00298121; iTF_00294283; iTF_00295821; iTF_00295055; iTF_00296586; iTF_00297360; iTF_00292754; iTF_00291349; iTF_00293531; iTF_01472992;
80% Identity
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