Basic Information

Insect: Tipula unca
Gene Symbol: -
Assembly: GCA_951394425.1
Location: OX596381.1:141417750-141425001[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 9.9e-06 0.0015 20.3 1.8 1 23 350 372 350 372 0.97

2 18 6.8e-06 0.001 20.8 0.2 1 23 378 400 378 400 0.97

3 18 0.00025 0.037 15.9 0.3 1 23 406 428 406 428 0.98

4 18 1e-06 0.00016 23.4 3.6 1 23 434 456 434 456 0.98

5 18 4.7e-05 0.007 18.2 4.7 1 23 462 484 462 484 0.99

6 18 7.9e-06 0.0012 20.6 3.5 1 23 490 512 490 512 0.97

7 18 5.8e-07 8.6e-05 24.2 5.0 1 23 518 540 518 540 0.98

8 18 1.7e-07 2.5e-05 25.9 2.5 1 23 546 568 546 568 0.97

9 18 8.8e-05 0.013 17.3 6.7 1 23 574 596 574 596 0.97

10 18 3.4e-06 0.0005 21.8 5.9 1 23 602 624 602 624 0.98

11 18 1.2e-07 1.9e-05 26.3 3.1 1 23 630 652 630 652 0.98

12 18 7.5e-06 0.0011 20.7 7.7 1 23 658 680 658 680 0.98

13 18 4.1e-06 0.0006 21.5 6.7 1 23 686 708 686 708 0.98

14 18 4.2e-05 0.0062 18.3 5.9 1 23 714 736 714 736 0.97

15 18 4.3e-05 0.0064 18.3 5.0 3 23 744 765 743 765 0.96

16 18 6.2e-05 0.0093 17.8 0.5 1 23 771 793 771 793 0.98

17 18 0.0099 1.5 10.9 3.9 1 23 803 825 803 825 0.98

18 18 7.9e-07 0.00012 23.8 3.5 1 23 831 853 831 853 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	9.9e-06	0.0015	20.3	1.8	1	23	350	372	350	372	0.97
2	18	6.8e-06	0.001	20.8	0.2	1	23	378	400	378	400	0.97
3	18	0.00025	0.037	15.9	0.3	1	23	406	428	406	428	0.98
4	18	1e-06	0.00016	23.4	3.6	1	23	434	456	434	456	0.98
5	18	4.7e-05	0.007	18.2	4.7	1	23	462	484	462	484	0.99
6	18	7.9e-06	0.0012	20.6	3.5	1	23	490	512	490	512	0.97
7	18	5.8e-07	8.6e-05	24.2	5.0	1	23	518	540	518	540	0.98
8	18	1.7e-07	2.5e-05	25.9	2.5	1	23	546	568	546	568	0.97
9	18	8.8e-05	0.013	17.3	6.7	1	23	574	596	574	596	0.97
10	18	3.4e-06	0.0005	21.8	5.9	1	23	602	624	602	624	0.98
11	18	1.2e-07	1.9e-05	26.3	3.1	1	23	630	652	630	652	0.98
12	18	7.5e-06	0.0011	20.7	7.7	1	23	658	680	658	680	0.98
13	18	4.1e-06	0.0006	21.5	6.7	1	23	686	708	686	708	0.98
14	18	4.2e-05	0.0062	18.3	5.9	1	23	714	736	714	736	0.97
15	18	4.3e-05	0.0064	18.3	5.0	3	23	744	765	743	765	0.96
16	18	6.2e-05	0.0093	17.8	0.5	1	23	771	793	771	793	0.98
17	18	0.0099	1.5	10.9	3.9	1	23	803	825	803	825	0.98
18	18	7.9e-07	0.00012	23.8	3.5	1	23	831	853	831	853	0.97

Sequence Information

Coding Sequence: atgaattcggAAAATTTACAATCGGAAGAGAATAATTCGCAGCTCGGAAGTCAGgaaGTTTTATCAACTATAACTCCGGATGCGTCTATGATTTTGGGCACCAGTCCACATTCATTGCCAATATCATTACCATCTGGATCATCATTGAATATACCATCTTCGGTAGATTCTACAGCAGCGctgcaatcaaatttaaatttaacatcatCACTTCATAATAATTTGATTGGTAATGATAATCATTCCAGTGCTTTACAATTACATCCGCCACCACCTCAGCAACAAATGCAAATGGGTCAAGATGGATTAATTATGGATGTGCGTCAGGCACCAAAAGAGTTGAAAGTATTTGAATCATCACAATTGGAACATTATCAacagcaacagcagcagcagcagcaacaacaacaacagcagcagcaacaacaacatcaatCTCAACAATCACAACAACAGCAACCACAGTTATCACCTCCAAGTCATCGACAAGATAATCGTCCTATCGATCATTCAATCAATAATTCCGATTCGCTTCATTTACCGCAAGTTCATGTGAACTCTGAGATTCGGAATAATGAACCAATGCTGAATGTAAAAGATACCAAgttacataattcaaaattaaatcttcAAAGTGTGCAACAACAATTTTCAGATCAGCaaagcgatttgaaatcgaattcaAGTCAATCACAATTAATGGATGTTAGAACAGCTGACGGTTCTATCGTTAAAATAGCTGGTGGTATTCAGGAACAAGATTTAACAATGTACAAAGTAAATATCGatgatttaaatcaatttttaacatGTCAtgaaattttcggtaaattgccCAATGATATGTTGGCTATGCCTACTGCTGGAATGTCTACTAATCCTATAAGTAGTGTGAGCACGAGTACCACAACATCAACGATCACCGATAGTCATAGAGATGATGGATGCTCAATTTCGCCAAAAGAGGAAAATAGTATGGGACAAGGAGGATCGGCTTCGGGAAGTGGTTTGAATGAAGATTCTAAAGCTCAACTTTCACAAGCCGTGCATTCATGTGATATTTGTGGGAAAATGTTTCCATTTCGTTACCAATTAATCGTACACAGACGTTACCATAATGAGAGAAAGCCATTTATATGTCAAGTGTGTGGTCAAGCGTTTAACACATCTGATGAGCTAACAAAGCATGGGAAAGTTCATCTCGGTGGTTCAATGTTTATATGTACTGTTTGCTTTAATGTTTTTGCTAATGATGCTAGTCTTGAACGACATATGAAACGACATTCGGCTGATAAACCGTTCTCATGCACGATATGTCAAAAAACGTTTGCGCGCAAAGAACATCTTGAAAATCACACGCGAAGTCATACAGGTGAAACACCATTTCGATGTCAGTACTGTGCTAAAACTTTTACACGTAAAGAGCACATGGTAAATCATGTGCGAAAGCATACCGGAGAGACTCCATTCCGTTgtgatatttgtaaaaaatcatttacCAGAAAGGAGCATTATATGAATCATGTTATGTGGCATACAGGTGAAACACCTCATCAATGTACTGTTTGTGGAAAGAAATATACAAGAAAAGAACATTTAGCTAATCATATGAGATCACACACAAATGAGACACCATTCCGTTGTGAAATTTGCGGAAAATCATTTACTAGAAAAGAACATTTCACTAATCACATACTATGGCACACGGGTGAGACACCTCATCGTTGTGACTTTTGTTCAAAAACTTTTACTCGAAAGGAACATCTCTTAAATCATGTACGACAGCATACTGGTGAATCTCCACATCGGTGTGAATATTGTTCAAAGTCATTTACACGGAAAGAGCATCTCGTCAATCATATCAGACAACATACAGGCGAGACTCCATTTAAGTGCACCTATTGTCCAAAGGCATTTACTCGAAAGGATCATTTGGTGAATCATATCCGTCAACATACTGGCGAATCGCcccataaatgtacatattgttCAAAATCTTTCACACGAAAGGAACATTTAACTAATCATGTACGGCAACATACCGGAGAACTTCCACATCGTTGTCAGTACTGTTCAAAATCATTCACACGAAAAGAACATTTGACAAATCATGTCCGAATTCATACTGGAGATTCGCCACATCGTTGTGATTTCTGCCAAAAAACGTTCACCCGCAAAGAGTATTTAACAAATCATTTGAAACAGCATAGCCAGGATAATCCAAACTGTTGTAATATTTGCTCAAAACCTTTTACACGGAAAGAACATTTAATAAATCACATGAGCCGATCGCATACTGGTGAGCGTCCATTTTCTTGTGATGAATGTGGAAAATCATTTCCATTGAAAGGAAATCTATTATTTCACCAGCGAAGCCATAATAAAGGAAGTACAGCGGAAAGACCATTTCGTTGTGATTTATGCCCAAAGGATTTTATATGTAAAGGACATTTGGTTTCACATCGACGATCACACTCTGATGAAAGACCCCACATATGTGAACATTGCGGCAAAACCTTTGTTGAAAAAGGTAATCTATTACGTCATATGAAGAAACATGTATTGGATACAGCGTATGCTCAAATTCCGAAATTGGAGCCAGgTACACAATTTGCAGGACCAAAGGTAGAACCAGgcacacaattttcgaatttatctGATGCAATTTCTACAGTAGTTACATCAATGGAGACCCAGTCAAATAACACAGATGCTATAATTACGTCAAATGCATCTTTGTCGAATAATTACAATCCTGCAGATAACAAAATCTCGAACtctcaacaacagcaacaacctGTATCTATAATTTCACATTCTCAGGATCATCAAATGAATTCTTCGAATGATACGAATCGAACAAGTGGTTCACTACAAATGCATCATTTAAATACATCACAGGAACATCATGTTGTATATTAA
Protein Sequence: MNSENLQSEENNSQLGSQEVLSTITPDASMILGTSPHSLPISLPSGSSLNIPSSVDSTAALQSNLNLTSSLHNNLIGNDNHSSALQLHPPPPQQQMQMGQDGLIMDVRQAPKELKVFESSQLEHYQQQQQQQQQQQQQQQQQQHQSQQSQQQQPQLSPPSHRQDNRPIDHSINNSDSLHLPQVHVNSEIRNNEPMLNVKDTKLHNSKLNLQSVQQQFSDQQSDLKSNSSQSQLMDVRTADGSIVKIAGGIQEQDLTMYKVNIDDLNQFLTCHEIFGKLPNDMLAMPTAGMSTNPISSVSTSTTTSTITDSHRDDGCSISPKEENSMGQGGSASGSGLNEDSKAQLSQAVHSCDICGKMFPFRYQLIVHRRYHNERKPFICQVCGQAFNTSDELTKHGKVHLGGSMFICTVCFNVFANDASLERHMKRHSADKPFSCTICQKTFARKEHLENHTRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPFRCDICKKSFTRKEHYMNHVMWHTGETPHQCTVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCEYCSKSFTRKEHLVNHIRQHTGETPFKCTYCPKAFTRKDHLVNHIRQHTGESPHKCTYCSKSFTRKEHLTNHVRQHTGELPHRCQYCSKSFTRKEHLTNHVRIHTGDSPHRCDFCQKTFTRKEYLTNHLKQHSQDNPNCCNICSKPFTRKEHLINHMSRSHTGERPFSCDECGKSFPLKGNLLFHQRSHNKGSTAERPFRCDLCPKDFICKGHLVSHRRSHSDERPHICEHCGKTFVEKGNLLRHMKKHVLDTAYAQIPKLEPGTQFAGPKVEPGTQFSNLSDAISTVVTSMETQSNNTDAIITSNASLSNNYNPADNKISNSQQQQQPVSIISHSQDHQMNSSNDTNRTSGSLQMHHLNTSQEHHVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01457737;
90% Identity: iTF_01457737; iTF_01460467; iTF_01456654;
80% Identity: -