Tshe047668.1
Basic Information
- Insect
- Timema shepardi
- Gene Symbol
- -
- Assembly
- GCA_902151425.1
- Location
- CABFVX010007213.1:1-8412[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0038 1 12.3 1.7 1 23 166 188 166 188 0.98 2 12 5.2e-05 0.014 18.2 0.3 1 23 194 216 194 216 0.96 3 12 0.00022 0.06 16.2 2.0 1 23 222 244 222 244 0.94 4 12 1.1e-05 0.003 20.3 1.4 1 23 250 272 250 272 0.99 5 12 0.00059 0.16 14.9 0.2 1 23 278 302 278 302 0.91 6 12 4e-05 0.011 18.5 2.3 1 23 308 330 308 330 0.98 7 12 5.6e-06 0.0015 21.2 1.7 1 23 335 358 335 358 0.97 8 12 0.00071 0.19 14.6 0.2 1 23 367 390 367 390 0.96 9 12 3.6e-05 0.0099 18.7 0.3 3 23 398 418 396 418 0.98 10 12 1.8e-05 0.005 19.6 0.2 1 23 424 446 424 446 0.97 11 12 1.1e-05 0.003 20.3 2.5 1 23 454 476 454 476 0.95 12 12 0.0046 1.2 12.1 1.9 1 23 482 504 482 504 0.98
Sequence Information
- Coding Sequence
- NNAGTGTCACAGATGGAGGACTCCTCGGGTTCTCAACTTCCGGTCAAAAACGAATTCGCCGGACATTTTATGTACGTTGAACCAGATTTGGGGCCCTTTATGAACGTGAAAGAGGAAAGGGCAGAGGACGAATCAGAGGAGAGCTCGAGTGAACCAACAGAAAGGGGTGAGGATGATAACAGGGCCGGCAATTCTGAAGAAGCCCTCTTTCTGACGGACGAGAAGTTGAGGAAGCTGTGTTTGGAAGACATCATCAAACATAACCACCTGTTGACAGGCTCCGAGGCAACAAACTTGTGGAAAATAAGGGCTTCCTTGcagaagaaaataaagaagCTTGAAGCGAAGAGGAACACCGCGGACAAAGATACCGCAACGTTTGAACAGAATAACAAAAGAAAATTGCGTAAGTCTGTTAAAGCTATGAAAGTGAGATTAAAGGTTAAAGAGAGTGAGGTAAAGAAAAGGTCCCAAGACGTGTCTACGAAAGACCTATTTAACTGTGTGCACTGCAATGACATTTTCGACACGTCTTTTGAATTGCGCGGACATTTGCGAACGCACACCCCCGCCAAATGTTTCCCGTGCCCAGAGTGCGACCTGTCGTTCACTCTGAAGAAGTCCCTGAAAGATCATTCGCTGGTCCACGCTGACAAGTATGCGTTCAACTGCGTGACCTGTCAGAAACCGTTCAGCAACAAGCAGACCCTGCGGCGGCACTCGTACATCCACCTCGACGTGAAGCCCTTCAAGTGCTCCGAGTGTCAGCGCGCCTTCGCAGACCATGGGGTCCTCAGACGTCACCTGAACACTCACTTCGGTATCAAACCTTACAAGTGTCTGGACGAGGCCTGCGGTAAAAACTTTGGTCGCAAGAGCGACCTGAAGGAGCACTCGCTCATCCACACCGACGAGAAACCCTTCACCTGCGAAGAGTGCGGCCACTCGTTCCGCTGGAAGAACAACCTGCGCTCTCATCTACTCACTCACCGAGGGGAGACTTTCAGTTGCGCGCTCTGCGACAAGAGCTTCTCTCGAAAGTTCACGTTGGATCAACACATGTCGACCAATCACAGCGGAAAGGAGCGCGAGAGGAAGTTTGTGTGCTCGCTCTGCGGGGCCAGCTTCTTGACCAAGTCGGGCCTCCAGGACCACACCAACATAACTCACAGCGACGTCCGGCCGTTCGGGTGTCCCATATGTGGCCAGGCCTTCAAGTGGAAATATTACCTCAAGACTCATCAACGCATTCACGTGGGGGAGAGGCGGTTCACGTGTCCAGTGTGCTCCAAAGGTTTCTTCCGCAGCGGGGACCTGAACGAACACCAGGTGGTTCATATCGAGGACCGACCGCGGCCCCACGAGTGCGCGTTGTGCGGGAAGACCTTCACCAGTAAACACCTTCTGAGGAAGCACGGCATCATCCACACGGGCGTCCGCCCCTACAAGTGTGACATTTGTTCCAAAGACTTTATTTGGTGCACGTCGCTTCGGAAGCACCGAGCGGTACACGGGGAGCAAGGACTCAAGTACCTTTGTTGA
- Protein Sequence
- XVSQMEDSSGSQLPVKNEFAGHFMYVEPDLGPFMNVKEERAEDESEESSSEPTERGEDDNRAGNSEEALFLTDEKLRKLCLEDIIKHNHLLTGSEATNLWKIRASLQKKIKKLEAKRNTADKDTATFEQNNKRKLRKSVKAMKVRLKVKESEVKKRSQDVSTKDLFNCVHCNDIFDTSFELRGHLRTHTPAKCFPCPECDLSFTLKKSLKDHSLVHADKYAFNCVTCQKPFSNKQTLRRHSYIHLDVKPFKCSECQRAFADHGVLRRHLNTHFGIKPYKCLDEACGKNFGRKSDLKEHSLIHTDEKPFTCEECGHSFRWKNNLRSHLLTHRGETFSCALCDKSFSRKFTLDQHMSTNHSGKERERKFVCSLCGASFLTKSGLQDHTNITHSDVRPFGCPICGQAFKWKYYLKTHQRIHVGERRFTCPVCSKGFFRSGDLNEHQVVHIEDRPRPHECALCGKTFTSKHLLRKHGIIHTGVRPYKCDICSKDFIWCTSLRKHRAVHGEQGLKYLC*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01445867; iTF_01448821; iTF_01446847; iTF_01447780; iTF_01449867; iTF_01445019;
- 90% Identity
- iTF_01445019;
- 80% Identity
- -