Tdou048663.1
Basic Information
- Insect
- Timema douglasi
- Gene Symbol
- -
- Assembly
- GCA_901482245.1
- Location
- CABEEJ010009887.1:8995-11983[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0039 0.94 12.3 1.7 1 23 162 184 162 184 0.98 2 12 5.4e-05 0.013 18.2 0.3 1 23 190 212 190 212 0.96 3 12 0.00023 0.054 16.2 2.0 1 23 218 240 218 240 0.94 4 12 1.1e-05 0.0027 20.3 1.4 1 23 246 268 246 268 0.99 5 12 0.00061 0.14 14.9 0.2 1 23 274 298 274 298 0.91 6 12 4.2e-05 0.0099 18.5 2.3 1 23 304 326 304 326 0.98 7 12 5.8e-06 0.0014 21.2 1.7 1 23 331 354 331 354 0.97 8 12 0.00073 0.17 14.6 0.2 1 23 363 386 363 386 0.96 9 12 3.8e-05 0.009 18.7 0.3 3 23 394 414 392 414 0.98 10 12 1.9e-05 0.0045 19.6 0.2 1 23 420 442 420 442 0.97 11 12 1.1e-05 0.0027 20.3 2.5 1 23 450 472 450 472 0.95 12 12 0.0047 1.1 12.1 1.9 1 23 478 500 478 500 0.98
Sequence Information
- Coding Sequence
- ATGGAGGACTCCTCGGGTTCTCAACTTCCGATCAAAAACGAATTCGCCGGACATTTTATGTACGTTGAACCAGATTTGGGGCCCTTTATAAACGTGAAAGAGGAAAGGGCAGAGGACGAATCAGAAGAGAGCTCGAGTGAACCAACAGAAAGGGGTGAGGATGAAAACAGTGCCGGCAATTCGGAAGAAGCCCTCTTTCTGACGGACGAGAAGTTGAGGAAGCTGTGTTTGGAAGACATCATCAAACATAATCACCTGTTGACAGGCTCCGAGGCGACAAACTTGTGGAAAATAAGGGCTTCCTTGcagaagaaaataaagaagcTTGAAGCGAAGAGGAACATCGCAGACAAAGATACCGCAACGTTTGAACAGAATAACAAAAGAAAATTGCGTAAGTCTGTTAAAGCTATGAAAGTGAGATTAACAGTTAAAGACAGTGAGGTAAAGAAAAGGTCCCAAGACGTGTCTACGAAAGACCTATTTAACTGTGTGCACTGCAATGACATTTTTGACACGTCTTTTGAACTGCGCGGACATTTGCGAACGCACACCCCCGCCAAATGTTTCCCGTGCCCAGAGTGCGACCTGTCGTTCACTCTGAAGAAGTCCCTGAAAGATCATTCGCTGGTCCACGCTGACAAGTATGCGTTCAACTGCGTGACCTGTCAAAAACCGTTCAGCAACAAGCAGACCCTGCGACGGCACTCGTACATCCACCTCGACGTTAAGCCCTTCAAGTGCTCCGAGTGTCAGCGCGCCTTCGCAGACCACGGGGTCCTCAGACGTCACCTGAACACTCACTTCGGTATCAAACCTTACAAGTGTCTGGACGAGGCCTGCGGTAAAAACTTTGGTCGCAAGAGCGACCTGAAGGAGCACTCGCTCATCCACACCGACGAGAAACCCTTCACTTGCGAAGAGTGCGGCCACTCGTTCCGCTGGAAGAACAACCTGCGCTCTCATCTACTCACTCACCGAGGGGAGACTTTCAGTTGCGCGCTCTGCGACAAGAGCTTCTCTCGAAAGTTCACGTTGGATCAACACATGTCGACCAATCACAGCGGAAAGGAGCGCGAGAGGAAGTTTGTGTGCTCGCTGTGTGGGGCCAGCTTCTTGACCAAGTCGGGCCTCCAGGACCACACTAACATAACTCACAGCGACGTCCGGCCGTTCGGGTGTCCCATATGTGGCCAGGCCTTCAAGTGGAAATATTACCTCAAAACTCATCAACGCATTCACGTGGGGGAGAGGCGGTTCACGTGCCCGGTGTGCTCCAAAGGTTTCTTCCGCAGCGGGGACCTGAACGAACACCAGGTGGTTCATATCGAGGACCGACCGCGGCCCCACGAGTGCGCGTTGTGCGGGAAGACCTTCACCAGTAAACACCTTCTGAGGAAGCACGGTATCATCCACACAGGCGTCCGCCCCTACAAGTGTGACATTTGTTCCAAAGACTTTATTTGGTGCACGTCGCTTCGGAAGCACCGAGCGGTACACGGGGAGCAAGGACTCAAGTACCTTTGTTGA
- Protein Sequence
- MEDSSGSQLPIKNEFAGHFMYVEPDLGPFINVKEERAEDESEESSSEPTERGEDENSAGNSEEALFLTDEKLRKLCLEDIIKHNHLLTGSEATNLWKIRASLQKKIKKLEAKRNIADKDTATFEQNNKRKLRKSVKAMKVRLTVKDSEVKKRSQDVSTKDLFNCVHCNDIFDTSFELRGHLRTHTPAKCFPCPECDLSFTLKKSLKDHSLVHADKYAFNCVTCQKPFSNKQTLRRHSYIHLDVKPFKCSECQRAFADHGVLRRHLNTHFGIKPYKCLDEACGKNFGRKSDLKEHSLIHTDEKPFTCEECGHSFRWKNNLRSHLLTHRGETFSCALCDKSFSRKFTLDQHMSTNHSGKERERKFVCSLCGASFLTKSGLQDHTNITHSDVRPFGCPICGQAFKWKYYLKTHQRIHVGERRFTCPVCSKGFFRSGDLNEHQVVHIEDRPRPHECALCGKTFTSKHLLRKHGIIHTGVRPYKCDICSKDFIWCTSLRKHRAVHGEQGLKYLC*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01450824;
- 90% Identity
- iTF_01445019;
- 80% Identity
- -