Basic Information

Insect: Timema genevievae
Gene Symbol: -
Assembly: GCA_902155825.1
Location: CABFWO010000638.1:94164-115543[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 5.8 1.1e+03 2.4 0.2 2 23 136 158 135 158 0.92

2 18 8.4 1.6e+03 1.9 1.2 3 23 163 184 161 184 0.89

3 18 0.38 71 6.1 0.4 2 23 188 210 187 210 0.94

4 18 0.021 4 10.0 0.3 5 23 502 521 497 521 0.87

5 18 0.0041 0.76 12.3 3.5 1 23 599 622 599 622 0.98

6 18 2.5 4.6e+02 3.6 2.2 1 23 633 656 633 656 0.92

7 18 0.027 5.1 9.7 3.3 1 23 662 685 662 685 0.93

8 18 1.2 2.2e+02 4.5 1.3 2 23 692 714 692 714 0.94

9 18 0.0023 0.43 13.1 2.4 1 23 722 745 722 745 0.97

10 18 0.00062 0.12 14.9 1.2 1 23 751 773 751 773 0.96

11 18 6e-06 0.0011 21.2 0.4 2 23 780 801 779 801 0.97

12 18 1e-07 2e-05 26.8 2.5 1 23 806 828 806 828 0.98

13 18 0.00031 0.058 15.8 4.8 1 23 834 856 834 856 0.99

14 18 2e-05 0.0037 19.6 1.9 2 23 863 884 862 884 0.97

15 18 5.7e-05 0.011 18.1 0.4 2 23 891 912 890 912 0.96

16 18 0.0012 0.23 13.9 0.3 3 23 920 941 919 941 0.92

17 18 4.5e-05 0.0084 18.5 0.1 1 23 947 969 947 969 0.98

18 18 0.0014 0.26 13.8 0.9 2 23 976 998 975 998 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	5.8	1.1e+03	2.4	0.2	2	23	136	158	135	158	0.92
2	18	8.4	1.6e+03	1.9	1.2	3	23	163	184	161	184	0.89
3	18	0.38	71	6.1	0.4	2	23	188	210	187	210	0.94
4	18	0.021	4	10.0	0.3	5	23	502	521	497	521	0.87
5	18	0.0041	0.76	12.3	3.5	1	23	599	622	599	622	0.98
6	18	2.5	4.6e+02	3.6	2.2	1	23	633	656	633	656	0.92
7	18	0.027	5.1	9.7	3.3	1	23	662	685	662	685	0.93
8	18	1.2	2.2e+02	4.5	1.3	2	23	692	714	692	714	0.94
9	18	0.0023	0.43	13.1	2.4	1	23	722	745	722	745	0.97
10	18	0.00062	0.12	14.9	1.2	1	23	751	773	751	773	0.96
11	18	6e-06	0.0011	21.2	0.4	2	23	780	801	779	801	0.97
12	18	1e-07	2e-05	26.8	2.5	1	23	806	828	806	828	0.98
13	18	0.00031	0.058	15.8	4.8	1	23	834	856	834	856	0.99
14	18	2e-05	0.0037	19.6	1.9	2	23	863	884	862	884	0.97
15	18	5.7e-05	0.011	18.1	0.4	2	23	891	912	890	912	0.96
16	18	0.0012	0.23	13.9	0.3	3	23	920	941	919	941	0.92
17	18	4.5e-05	0.0084	18.5	0.1	1	23	947	969	947	969	0.98
18	18	0.0014	0.26	13.8	0.9	2	23	976	998	975	998	0.94

Sequence Information

Coding Sequence: ATGAGTCAAAGTGAGGGAAATGATTCCAGTTTGGAGCGGGCACGCTTCCCACTCTATCATCACTcgaagaaaaataagaaaaaaggtGAAAAGTCTAGCATGAGACGGCATTTGAGTGATAATAAGATGGAGACTGAAGAGGAAGTATCTAAAGGAGGGGGAAGTGACACAGATGGCAACGTCCCTGCAGCCTCTGACCTTCCTTTGTGTGTCCCACATTTGTTGGCCCCGGCCCCTATCCCTTGTCAATCACTAATAACCAAGGCTTGGTCATCTCCCACTCCTGCATCATCTCTTCAAATTAGTGGCCCATCGGGTACCATGCCTAGTATTTCCAGCCGCAAGGAGGTCCAAGCTCTTCCTAAAAGAAATGAATACACATCAGCTTCCATACCAAAAACTGTTGTATGTTTCATTTGCAAGGAATGGTTTTTTTCTAGAGAAAAGTTCATAATTCACTTGGTGATGAACCACAGAATGGTGCATTGTCGTCACTGTCAGGAGATTTTTGAAACTGATGATATGCGTATTCTTCACGAAAGAGAAGTACATTTCCCTTTAGAATGTGATATATGTAAGTGCACAGTTGAATCAACTAAAGAGCTGGCAGAACATTATGAGAGTGATCATGATGTACGTACGTGCTTGTTTTGTGGAGTTTTAGTGAAACCCAAATCATATTACAGTGTGCATCTTGCGAAAAGTAAAAAGGAAGATTCCAACTTTGGAGATCAAATTGATGGATCTGAGAAATTCAACTCCGATTCTTCATTTGAGCCTTCTTCAGATGAGTTTTTGGTTGGCTCTGGAGGAGAGAATGAAGAACTATctgatgaagaagaagaagaatggaaaccAGATGTAATAGCAAATTTAAACGATGAACCAATTGAGGCACAAATAGATCCAACAGAAGTAGAATGTGTAATGAATGACACTAGTGACGATGAATTTTATGATGATACCTCACCTATACTGGAAGATAATGAAGGaagtgataattttatttcaaatatgcaGATAAATCAAGAAAAAATAGAGGCCATGATTGACAGCTTGAACACTGGTCTTGATGAGGCAAGTCATGAAAAGAATGCGGAGACGAGCTCAGAAAACTTAAGAAAGATATCAACACTATCCTCAGGGGAAAGCCAGCCCTTAACACTAGACACAGACACTGTTGAAGATCAGATAGAAAAGATGTTTCAGGACCCTTCCAAAACCACAGAACAGCTCGGTGAGCCTGCTACTTCCAATGGGAAAGTTGCCAGTCGGGAAAGCTGGGAAGCTGCAGATGTTCTAATGGCTATCAAGCAAGAGCCAGGAACTGATGTAGATGGTAACTTTCCATTCCCAAGCCAAAAGAAAAATggtaaagaaatgttttgtgaAATTTGCTGTGGTCCATGTCCAGGGCTGGAAGAATTATTGCAGCACTTAAATACTGTCCATAATTTTTCTATCATGGCTTTGGGCGGTGAAAGTAGATTCACTTGTATAGAGGagtgtgataaaatatttaattctcaaGCCTTGCTGgacaaacataaaaaagaagTGCATAAAATTACCAAAGTGACGACAACGTTCCAATGTCCGTTCTGTGCTGTTCAAGCAGAGACGAAAATCACTGTGAGACAGCACATTTTTGACTTTCACAACAATGATTTGATGTCGGAACCTCCACAGAGACCATTTGCTTTCCCATGTCGATGTTGTGCAAAAAAGTTTTGGCATGTTGAAGAAAGAAATCAACATCAGATGGATGAGCATTCCGACACTATTGAAAGTTTCTTCAAGTGCTACATATGCCTTCAATCATATACAAGCAAGGTATGTTTGAATCGTCATGTCTTGACAACACATCCTGGTGAACAGCGCTACTCTCCTCTCTCGTACAAGTGCAAGCTGTGTCTTGTCATGTTTCCCAGTGTGGCCAAGATGTGCAAACATTTCCAGGACTCTCACCCCGCCGCTCTCGTCTTCCTTTGCCGTTTCTGCAACATGactctaaaaacaaaaaaaactctcaaGACTCACATTAAGAACATGCACTCACAGGCTCGCCAACGTGAGTGCCATCTTTGTGGCAAAATGCTATTGAGTAAACGAGCGTATGCGATACATTTCCGCATGAAGCACAGTGCAATCTCCAGAGTAGGCTTCCGCTGCCGTATCTGTCAAAAGAGATTTGACTCTAAGGATGAGAGAAAGCTGCACTATCAAATGGACCATGAAGGTGAAAGCCCGTATCACTGCACAGACTGTGGTAAAGGCTTTGCCTCAAAGTCAGGCATGTACGGGCACAGGCAGCTGCATACAGGAACTGGCGTGTCAACCTGCGGTTACTGCGGCAAGGCTTTCACACGCAAGGACAGCTACAACGAACACTTATTGATCCACAATGGGCCACGACACAAGTGCCCTCACTGTCCTAAAGAATTTGTGCAACGCTCTAACTTGGTGCGACATATTCGTATCCACACAGgCGAAAAACCTTATAAATGCTTGTATTGTGACAAGTGTTTTTCTGACAAAGGGGCGTGCAACTCACATATCCGTGTTCACACCCGTGAGGAAACCTCTTCTTGTCCTTATTGCGGTCAAACATATTCCAAAAAACAGAAATTGAAGTACCATATTCGTAAACACACAGGAGAAGGTTTAATCACTTGTGAAATTTGCAACAAGcaATTTACAAACAGTTTTGCCTTGAAAGAACATCGTATCATTCATGATAGACAAACCCAAATCTTGTGTCGTCGTTGTGGAAAAGCTTTCAACAGTGAAAAATATCTACAACGACATGTGGCACTTGTACACGAACCTTCTCACATGTACAACTGCCCACTATGTTCGAAGGCGTTCTCCTTGCCAGGACGATTGAAAGCCCATATCATGACCCACACCGGTGTGAAACACATGAAGTGCCTCCTTTGCGACAAAGCGTACTCTGTTCGTAAGTCTCTACGTAAACACTTGTTAGAGAAACACAATGTGGGTCATGACCATCCCCACTACAAACGTTGTTTCTATGCAATGTCTCCTGAGGAAGCAGGTCTAGACATTCCCTCAGGTAGTGAGGATGAGCCTGCGATCCCAATCTTCCGCAAACAAGAAGTtaaaaagaaagtgaaaaagCCCCGAGGGACAGGTCGTAGGGGGCGACCTCCTGGCAGTGGTAAAAAACAGAAACAGAGTGGGGATCCCTCTCTAGTAACCTCCCCGAAACGAGGTAGGGGTAGGGGTAGAGGCAGAGGTGGTGGTAGGGGAAGGGGTAGAGGTCGTCCACCCAAATCTCTTTCTATAGTTGTTAGTCCAGAACCATCAACATCTACCGGTACAGAATCTCAAAGAGTTTTGAGGAGGAAACCATCACCAAAGAAATTTGAAATCAAGCAAGAACCAGACTCCGAAGAAGATAGTGATTCAAATAATATGCTCTCTATGGCGCTCCAAGATGAAAAATCTCATAGTAGCACAGACTCTTACGAAGAGAAAATAACGAAGAAGAGGAGTGTTGGGAATAGGAAAATATCCCCAATGGAATATCATTCATCGGCTCCTACTTTGTCTCCTGAAAACAAAGAGATGTTGTTGAACCTTGTAGGAGCAACTGGCCAGAAGAAGCGAAGAGTGGAGGCGATTGTCGAGATCCTTCAGAAGTATACCAACACCGGAGCCGAGGGAAACTCAAAGGATGGTACCGGCGAAGATATCAAAGATGAGGATCAAAGACAAGAAACTCGCAGTAGACATGACAAGGAAAGCACGGAAGATAgaggatcgagtgacgaaggtGAAGGTCTGGTCGGTAATTATACAAAGGTTGATGTGcaagggaaaataaaagaagaagaatgttcGTTAGGAAGCAGTAGCGGGTCTAGTGTAGACCAACAGGATGTAAGTGATGAGGCTGAGGATAATGGGCCGGTCTTAGCACGCTTCAGTGCACTGGACAGTCCAAAAGTTAAATCAACACCATTGTCGCCATTAAAAATTAGGTTTCGAACACAATCATATGATGAGGAAGAGGAAGAAGATGGTGGCGATGAGGATGATGAGGATACTGATGAGAATGGGGTGGAtgcagatgatgatgatgatgacgagtCCAGCTAG
Protein Sequence: MSQSEGNDSSLERARFPLYHHSKKNKKKGEKSSMRRHLSDNKMETEEEVSKGGGSDTDGNVPAASDLPLCVPHLLAPAPIPCQSLITKAWSSPTPASSLQISGPSGTMPSISSRKEVQALPKRNEYTSASIPKTVVCFICKEWFFSREKFIIHLVMNHRMVHCRHCQEIFETDDMRILHEREVHFPLECDICKCTVESTKELAEHYESDHDVRTCLFCGVLVKPKSYYSVHLAKSKKEDSNFGDQIDGSEKFNSDSSFEPSSDEFLVGSGGENEELSDEEEEEWKPDVIANLNDEPIEAQIDPTEVECVMNDTSDDEFYDDTSPILEDNEGSDNFISNMQINQEKIEAMIDSLNTGLDEASHEKNAETSSENLRKISTLSSGESQPLTLDTDTVEDQIEKMFQDPSKTTEQLGEPATSNGKVASRESWEAADVLMAIKQEPGTDVDGNFPFPSQKKNGKEMFCEICCGPCPGLEELLQHLNTVHNFSIMALGGESRFTCIEECDKIFNSQALLDKHKKEVHKITKVTTTFQCPFCAVQAETKITVRQHIFDFHNNDLMSEPPQRPFAFPCRCCAKKFWHVEERNQHQMDEHSDTIESFFKCYICLQSYTSKVCLNRHVLTTHPGEQRYSPLSYKCKLCLVMFPSVAKMCKHFQDSHPAALVFLCRFCNMTLKTKKTLKTHIKNMHSQARQRECHLCGKMLLSKRAYAIHFRMKHSAISRVGFRCRICQKRFDSKDERKLHYQMDHEGESPYHCTDCGKGFASKSGMYGHRQLHTGTGVSTCGYCGKAFTRKDSYNEHLLIHNGPRHKCPHCPKEFVQRSNLVRHIRIHTGEKPYKCLYCDKCFSDKGACNSHIRVHTREETSSCPYCGQTYSKKQKLKYHIRKHTGEGLITCEICNKQFTNSFALKEHRIIHDRQTQILCRRCGKAFNSEKYLQRHVALVHEPSHMYNCPLCSKAFSLPGRLKAHIMTHTGVKHMKCLLCDKAYSVRKSLRKHLLEKHNVGHDHPHYKRCFYAMSPEEAGLDIPSGSEDEPAIPIFRKQEVKKKVKKPRGTGRRGRPPGSGKKQKQSGDPSLVTSPKRGRGRGRGRGGGRGRGRGRPPKSLSIVVSPEPSTSTGTESQRVLRRKPSPKKFEIKQEPDSEEDSDSNNMLSMALQDEKSHSSTDSYEEKITKKRSVGNRKISPMEYHSSAPTLSPENKEMLLNLVGATGQKKRRVEAIVEILQKYTNTGAEGNSKDGTGEDIKDEDQRQETRSRHDKESTEDRGSSDEGEGLVGNYTKVDVQGKIKEEECSLGSSSGSSVDQQDVSDEAEDNGPVLARFSALDSPKVKSTPLSPLKIRFRTQSYDEEEEEDGGDEDDEDTDENGVDADDDDDDESS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01445051; iTF_01445907; iTF_01448866; iTF_01449852;
90% Identity: iTF_01445051;
80% Identity: -