Basic Information

Gene Symbol
-
Assembly
GCA_902151445.1
Location
CABFVZ010001723.1:78312-109084[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 5.2 1.1e+03 2.5 0.2 2 23 136 158 135 158 0.92
2 17 5.6 1.2e+03 2.4 1.2 3 23 163 184 161 184 0.90
3 17 1.1 2.3e+02 4.6 0.2 2 21 188 207 187 208 0.91
4 17 0.0037 0.76 12.4 3.5 1 23 480 503 480 503 0.98
5 17 2.2 4.6e+02 3.7 2.2 1 23 514 537 514 537 0.92
6 17 0.025 5.1 9.8 3.3 1 23 543 566 543 566 0.93
7 17 1.1 2.2e+02 4.7 1.3 2 23 573 595 573 595 0.94
8 17 0.0021 0.43 13.2 2.4 1 23 603 626 603 626 0.97
9 17 0.00056 0.12 15.0 1.2 1 23 632 654 632 654 0.96
10 17 5.3e-06 0.0011 21.4 0.4 2 23 661 682 660 682 0.97
11 17 9.4e-08 1.9e-05 26.9 2.5 1 23 687 709 687 709 0.98
12 17 0.00028 0.058 15.9 4.8 1 23 715 737 715 737 0.99
13 17 1.8e-05 0.0037 19.7 1.9 2 23 744 765 743 765 0.97
14 17 5.1e-05 0.011 18.3 0.4 2 23 772 793 771 793 0.96
15 17 0.0011 0.23 14.1 0.3 3 23 801 822 800 822 0.92
16 17 4.1e-05 0.0084 18.6 0.1 1 23 828 850 828 850 0.98
17 17 0.0013 0.26 13.9 0.9 2 23 857 879 856 879 0.94

Sequence Information

Coding Sequence
ATGAGTCAAAGTGAGGGAAATGATTCCAGCTTGGAGCGGGCACGCTTCCCACTCTATCATCActcaaagaaaaataagaaaaaaggtGACAAGTCTAGCATGAGACGGCATTTGAGTGATAATAAGATGGAGATTGAAGAGGAAGTATCTAAAGGAGGGGGAAGTGACACAGATGGCAATATCCCTGTGGCCTCTGACCTTCCTTTGTGTGTCCCACATTTGTTGGCCCCGGCCCCTGTCCCTTGTCAATCAGTTATAACCAAGGCGTGGTCATCTCCCACTCCTGCATCATCTCTTCAAATTAGTGGCCCATCGGGTACCATGCCTAGTATTTCCAGCCGCAAGGAGGTCCAAGCTCTTCCTAAAAGAAATGAATACACATCAGCTGCTATACCAAAAACTGTTGTATGTTTCATTTGCAAGGAATGGTTTTTTTCTAGAGAAAAGTTCATAATTCACTTGGTGATGAACCACAGAATGGTGCATTGCCGACACTGTCAGGAGATTTTTGAAACTGATGATATGCGTATTATTCACGAAAGAGAATTACATTTCCCTTTAGAATGTGATATATGTAAGTGCACAGTTGAATCAACTAAAGAACTGGCAGAACATTATGAGACAAAAAGTAAAAAGGAAGATTCCAACTTTGGAGATCACATTGATGGATCTGAAAAATTCAACTCCGACTCTTCATTTGAGCCTTCTTCAGATGAGTTTTTGGTTGGCTCTGGAGGAGAGAATGAAGAATCTGatgaagaagaagaatggaaaccAGATGTAATAGCAAATTTAAACGATGAACCAATTGAGGCACAAATAGATCCAACAGAAGTAGAATGTGTAATGAATGACACTAGTGACGATGAATTTTATGACGATACCTCACCTATACAGGCAGATAGTGAAGGAAGTgataatttcatttctaatatGCAgataaatcaagaaaaaatagAGGCCATGATTGACAGCTTGAACACTGGTCTTGATGAGGAAAGTCATGAAAAGAGTGCAGAGACGAGCACAGAAAACTTAAGAAAGATATCAACACTATCCTCAGGGGAAAGCCAGCCCTTAACACTAGACACAGACACCGTTGAAGATCAGATAGAAAAGATGTTTCAGGCCCCTTCCAAAACCACAGAACAGCTCGCTGAACCTGCTACTTCCAATGGGAAAGTTGCCAGTCGGGAAAGTTGGGAAGCTGCAGATGTCCTAATGGCTATCAAACAAGAGCCAGGAACTGACGTGGATGCAGAGACGAAAATCACTGTGAGACAGCACATTTTTGACTTTCACAACAATGATTTGATGTCGGAGCCTCCACAAAGACCGTTTGCTTTCCCATGTCGATGTTGTTCAAAAAAGTTTTGGCATGTTGAAGAAAGAAATCAACATCAGATGGATGAGCATTCTGACACTATTGAAAGTTTCTTCAAGTGCTACATATGCCTTCAATCATATACAAGCAAGGTATGTTTGAATCGTCATGTCTTGACAACACATCCTGGTGAACAGCGCTACTCTCCTCTCTCGTACAAGTGCAAGCTGTGTCTTGTCATGTTTCCCAGCGTGGCCAAGATGTGCAAACATTTCCAGGACTCACACCCTGCCGCTCTCGTCTTCCTTTGTCGCTTCTGCAACATGACtctcaaaacaaaaaaaactctcaaGACTCACATTAAGAACATGCACTCACAGGCTCGCCAACGTGAGTGCCATCTTTGCGGCAAAATGCTATTGAGTAAACGAGCGTATGCGATACATTTCCGCATGAAGCACAGTGCAATCTCCAGAGTAGGTTTCCGCTGCCGTATCTGTCAAAAGAGATTTGACTCTAAGGATGAGAGAAAGCTGCACTATCAAATGGACCATGAAGGTGAAAGCCCATATCACTGCACAGACTGTGGTAAAGGCTTTGCCTCCAAGTCAGGCATGTACGGGCACAGGCAGCTGCATACAGGAACTGGCGTGTCAACATGTGGTTACTGCGGAAAGGCTTTCACACGCAAGGACAGCTACAATGAACACTTATTGATCCACAATGGGCCACGGCACAAGTGCCCTCACTGTCCTAAAGAATTTGTACAACGCTCTAATTTGGTGCGACATATTCGTATCCACACAGGTGAAAAACCTTATAAATGCTTGTATTGTGACAAGTGTTTTTCTGACAAAGGGGCATGCAACTCACATATCCGTGTCCACACCCGTGAGGAAACCTCTTCTTGTCCTTATTGCGGACAAACCTATTCAAAAAAACAGAAATTGAAGTACCATATTCGTAAACACACAGGAGAAGGATTAATCACTTGTGAAATTTGCAAcaagcaATTTACAAACAGCTTTGCCTTGAAAGAACATCGTATCATTCATGATAGACAAACCCAAATCTTGTGTCGTCGTTGTGGAAAAGCTTTCAATAGTGAAAAATATCTACAACGACATGTGGCACTTGTACACGAACCCTCCCACATGTACAACTGCCCACTATGTTCGAAGGCATTCTCCTTGCCTGGACGATTGAAAGCCCACATCATGACCCACACAGGTGTGAAACACATGAAGTGCCTCCTTTGCGATAAAGCGTACTCTGTTCGTAAGTCTCTACGTAAACACTTGTTAGAGAAACACAATGTGGGCCATGACCATCCACACTACAAACGTTGTTTCTATGCAATGTCTCCAGAGGAAGCAGGGCTAGACATTCCCTCAGGTAGTGAGGATGAGCCTGCCATACCAATCTTCCGCAAACAAGAAGttaaaaagaaagtgaaaaagCCTCGAGGGACAGGTCGTAGGGGGCGACCTCCTGGCAgtggtaaaaaacaaaaacagagTGGGGATCCCTCTTTAGTAACCTCCCCAAAACGTGGTAGGGGTAGGGGTAGAGGCAGAGGTGGTGGTAGGGGAAGGGGTAGAGGTCGTCCACCCAAATCTCTTTCTATAGTTGCTAGTCCAGAACCATCAACATCTACCGGTAGAGAATCTCAAAGAGTTTTGAGGAGGAAACCATCACCAAAGAAATTTGAAATCAAGCAAGAACCAGACTCCGAAGAAGATAGtgattcaaataatatgctttCTATGGCTCTCCAAGATGAAAAATCTCATAGTAGCACAGACTCTTACGAAGagaaaataacaaagaagagGAGTGTTGGGAATAGGAAAATATCCCCAATGGAATATCATTCATCGGCTCCTACTTTGTCTCCTGAAAACAAAGAGATGTTGTTGAACCTTGTAGGAGCAACTGGCCAGAAGAAGCGAAGAGTGGAGGCAATTGTCGAGATCCTTCAGAAGTATACCAACACCGGAGCCGAGGGAAACTCAAAGGATGGTACCGGTGAAGACATCAAAGATGAGGATCAAAGACAAGCAACTCACAGTAGACATGACAAGGAAAGCACAGAAGATAgaggatcgagtgacgaaggtGAAGGTCTGGTCGGTAAGTATACAAAGGTTGATGTacaagggaaaataaaagaagaagaatgttcATTAGAAAGCAGTAGCGGGTCTAGTATAGACCAACAGGATGTAAGTGATGAGGCTGAGGATAATGGGCCGGTCTTAGCACGCTTCAGTGCACTGGACAGTCCAAAAGTTAAATCAACACCATTATCTCCATTAAAAATTAGGTTTCGAACACAATCATATGATGAGGAAGAGGAAGAAGATGGTGgcgatgaggatgatgaggatacTGATGAGAATGGGGTGGAtgcagatgatgatgatgaagatgatgagtCCAGCTAG
Protein Sequence
MSQSEGNDSSLERARFPLYHHSKKNKKKGDKSSMRRHLSDNKMEIEEEVSKGGGSDTDGNIPVASDLPLCVPHLLAPAPVPCQSVITKAWSSPTPASSLQISGPSGTMPSISSRKEVQALPKRNEYTSAAIPKTVVCFICKEWFFSREKFIIHLVMNHRMVHCRHCQEIFETDDMRIIHERELHFPLECDICKCTVESTKELAEHYETKSKKEDSNFGDHIDGSEKFNSDSSFEPSSDEFLVGSGGENEESDEEEEWKPDVIANLNDEPIEAQIDPTEVECVMNDTSDDEFYDDTSPIQADSEGSDNFISNMQINQEKIEAMIDSLNTGLDEESHEKSAETSTENLRKISTLSSGESQPLTLDTDTVEDQIEKMFQAPSKTTEQLAEPATSNGKVASRESWEAADVLMAIKQEPGTDVDAETKITVRQHIFDFHNNDLMSEPPQRPFAFPCRCCSKKFWHVEERNQHQMDEHSDTIESFFKCYICLQSYTSKVCLNRHVLTTHPGEQRYSPLSYKCKLCLVMFPSVAKMCKHFQDSHPAALVFLCRFCNMTLKTKKTLKTHIKNMHSQARQRECHLCGKMLLSKRAYAIHFRMKHSAISRVGFRCRICQKRFDSKDERKLHYQMDHEGESPYHCTDCGKGFASKSGMYGHRQLHTGTGVSTCGYCGKAFTRKDSYNEHLLIHNGPRHKCPHCPKEFVQRSNLVRHIRIHTGEKPYKCLYCDKCFSDKGACNSHIRVHTREETSSCPYCGQTYSKKQKLKYHIRKHTGEGLITCEICNKQFTNSFALKEHRIIHDRQTQILCRRCGKAFNSEKYLQRHVALVHEPSHMYNCPLCSKAFSLPGRLKAHIMTHTGVKHMKCLLCDKAYSVRKSLRKHLLEKHNVGHDHPHYKRCFYAMSPEEAGLDIPSGSEDEPAIPIFRKQEVKKKVKKPRGTGRRGRPPGSGKKQKQSGDPSLVTSPKRGRGRGRGRGGGRGRGRGRPPKSLSIVASPEPSTSTGRESQRVLRRKPSPKKFEIKQEPDSEEDSDSNNMLSMALQDEKSHSSTDSYEEKITKKRSVGNRKISPMEYHSSAPTLSPENKEMLLNLVGATGQKKRRVEAIVEILQKYTNTGAEGNSKDGTGEDIKDEDQRQATHSRHDKESTEDRGSSDEGEGLVGKYTKVDVQGKIKEEECSLESSSGSSIDQQDVSDEAEDNGPVLARFSALDSPKVKSTPLSPLKIRFRTQSYDEEEEEDGGDEDDEDTDENGVDADDDDEDDESS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01447821;
90% Identity
iTF_01445907;
80% Identity
-