Tcri035571.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Timema cristinae
Gene Symbol
-
Assembly
GCA_002928295.1
Location
CM009483.1:23349170-23378381[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 4.6 6.7e+02 2.5 0.2 2 23 136 158 135 158 0.92
2 17 7.7 1.1e+03 1.8 1.4 3 23 163 184 161 184 0.89
3 17 0.3 44 6.2 0.4 2 23 188 210 187 210 0.94
4 17 0.0032 0.47 12.4 3.5 1 23 485 508 485 508 0.98
5 17 2 2.9e+02 3.7 2.2 1 23 519 542 519 542 0.92
6 17 0.022 3.2 9.8 3.3 1 23 548 571 548 571 0.93
7 17 0.95 1.4e+02 4.7 1.3 2 23 578 600 578 600 0.94
8 17 0.0018 0.27 13.2 2.4 1 23 608 631 608 631 0.97
9 17 0.0005 0.072 15.0 1.2 1 23 637 659 637 659 0.96
10 17 4.7e-06 0.00069 21.4 0.4 2 23 666 687 665 687 0.97
11 17 8.3e-08 1.2e-05 26.9 2.5 1 23 692 714 692 714 0.98
12 17 0.00025 0.036 15.9 4.8 1 23 720 742 720 742 0.99
13 17 1.6e-05 0.0023 19.7 1.9 2 23 749 770 748 770 0.97
14 17 4.5e-05 0.0066 18.3 0.4 2 23 777 798 776 798 0.96
15 17 0.00098 0.14 14.1 0.3 3 23 806 827 805 827 0.92
16 17 3.6e-05 0.0052 18.6 0.1 1 23 833 855 833 855 0.98
17 17 0.0011 0.16 13.9 0.9 2 23 862 884 861 884 0.94

Sequence Information

Coding Sequence
ATGAGTCAAAGTGAGGGAAATGATTCCAGCTTGGAGCGGGCACGCTTCCCACTCTATCATCActcaaagaaaaataagaaaaaaggtGACAAGTCTAGCATGAGACGGCATTTGAGTGATAATAAGATGGAGATTGAAGAGGAAGTATCTAAAGGAGGGGGAAGTGACACAGATGGCAATATCCCTGTGGCCTCTGACCTTCCTTTGTGTGTCCCACATTTGTTGGCCCCGGCCCCTGTCCCTTGTCAATCAGTTATAACCAAGGCGTGGTCATCTCCCACTCCTGCATCATCTCTTCAAATTAGTGGCCCATCGGGTACCATGCCTAGTATTTCCAGCCGCAAGGAGGTCCAAGCTCTTCCTAAAAGAAATGAATACACATCAGCTGCTATACCAAAAACTGTTGTATGTTTCATTTGCAAGGAATGGTTTTTTTCTAGAGAAAAGTTCATAATTCACTTGGTGATGAACCACAGAATGGTGCATTGCCGACACTGTCAGGAGATTTTTGAAACTGATGATATGCGTATTCTTCACGAAAGAGAATTACATTTCCCTTTAGAATGTGATATATGTAAGTGCACAGTTGAATCAACTAAAGAACTGGCAGAACATTATGAGAGTGATCATGATGTACCAAAAAGTAAAAAGGAAGATTCCAACTTTGGAGATCACATTGATGGATCTGAAAAATTCAACTCCGACTCTTCATTTGAGCCTTCTTCAGATGAGTTTTTGGTTGGCTCTGGAGGAGAGAATGAAGAATCTGatgaagaagaagaatggaaaccAGATGTAATAGCAAATTTAAACGATGAACCAATTGAGGCACAAATAGATCCAACAGAAGTAGAATGTGTAATGAATGACACTAGTGACGATGAATTTTATGACGATACCTCACCTATACAGGCAGATAGTGAAGGAAGTGataatttcatttctaataTGCAgataaatcaagaaaaaatagAGGCCATGATTGACAGCTTGAACACTGGTCTTGATGAGGAAAGTCATGAAAAGAGTGCAGAGACGAGCACAGAAAACTTAAGAAAGATATCAACACTATCCTCAGGGGAAAGCCAGCCCTTAACACTAGACACAGACACCGTTGAAGATCAGATAGAAAAGATGTTTCAGGCCCCTTCCAAAACCACAGAACAGCTCGCTGAACCTGCTACTTCCAATGGGAAAGTTGCCAGTCGGGAAAGTTGGGAAGCCGCAGATGTCCTAATGGCTATCAAACAAGAGCCAGGAACTGATGTGGATGCAGAGACGAAAATCACTGTGAGACAGCACATTTTTGACTTTCACAACAATGATTTGATGTCAGAGCCTCCACAGAGACCGTTTGCTTTCCCATGTCGATGTTGTTCAAAAAAGTTTTGGCATGTTGAAGAAAGAAATCAACATCAGATGGATGAGCATTCTGACACTATTGAAAGTTTCTTCAAGTGCTACATATGCCTACAATCATATACAAGCAAGGTATGTTTGAATCGTCATGTCTTGACAACACATCCTGGTGAACAGCGCTACTCTCCTCTCTCGTACAAGTGCAAGCTGTGTCTTGTCATGTTTCCCAGCGTGGCCAAGATGTGCAAACATTTCCAGGACTCACACCCTGCCGCTCTCGTCTTCCTTTGTCGCTTCTGCAACATGActctcaaaacaaaaaaaactctcaagACTCACATTAAGAACATGCACTCACAGGCTCGCCAACGTGAGTGCCATCTTTGCGGCAAAATGCTATTGAGTAAACGAGCGTATGCGATACATTTCCGCATGAAGCACAGTGCAATCTCCAGAGTAGGTTTCCGCTGCCGTATCTGTCAAAAGAGATTTGACTCTAAGGATGAGAGAAAGCTGCACTATCAAATGGACCATGAAGGTGAAAGCCCATATCACTGCACAGACTGTGGTAAAGGCTTTGCCTCCAAGTCAGGCATGTACGGGCACAGGCAGCTGCATACAGGAACTGGCGTGTCAACATGTGGTTACTGCGGAAAGGCTTTCACACGCAAGGACAGCTACAATGAACACTTATTGATCCACAATGGGCCACGGCACAAGTGCCCTCACTGTCCTAAAGAATTTGTACAACGGTCTAATTTGGTGCGACATATTCGTATCCACACAGGTGAAAAACCTTATAAATGCTTGTATTGTGACAAGTGTTTTTCTGACAAAGGGGCATGCAACTCACATATCCGTGTCCACACCCGTGAGGAAACCTCTTCTTGTCCTTATTGCGGACAAACCTATTCAAAAAAACAGAAATTGAAGTACCATATTCGTAAACACACAGGAGAAGGATTAATCACTTGTGAAATTTGCAAcaagcaATTTACAAACAGCTTTGCCTTGAAAGAACATCGTATCATTCATGATAGACAAACCCAAATCTTGTGTCGTCGTTGTGGAAAAGCTTTCAATAGTGAAAAATATCTACAACGACATGTGGCACTTGTACATGAACCCTCCCACATGTACAACTGCCCACTatGTTCGAAGGCATTCTCCTTGCCTGGACGATTGAAAGCCCACATCATGACCCACACAGGTGTGAAACACATGAAGTGCCTCCTTTGCGATAAAGCGTACTCTGTTCGTAAGTCTCTACGTAAACACTTGTTAGAGAAACACAATGTGGGTCATGACCATCCACACTACAAACGTTGTTTCTATGCAATGTCTCCAGAGGAAGCAGGTCTAGACATTCCCTCAGGTAGTGAGGATGAGCCTGCCATACCAATCTTCCGCAAACAAGAAGTtaaaaagaaagtgaaaaagCCTCGAGGGACAGGTCGTAGGGGGCGACCTCCTGGCAgtggtaaaaaacaaaaacagagtGGGGATCCCTCTTTAGTAACCTCCCCAAAACGTGGTAGGGGTAGGGGTAGAGGCAGAGGTGGTGGTAGGGGAAGGGGTAGAGGTCGTCCACCCAAATCTCTTTCTATAGTTGCTAGTCCAGAACCATCAACATCTACCGGTAGAGAATCTCAAAGAGTTTTGAGGAGGAAACCATCACCAAAGAAATTTGAAATCAAGCAAGAACCAGACTCCGAAGAAGATAGTGATTCAAATAATATGCTTTCTATGGCTCTCCAAGATGAAAAATCTCATAGTAGCACAGACTCTTACGAAGAGAAAATAACAAAGAAGAGGAGTGTTGGGAATAGGAAAATATCCCCAATGGAATATCATTCATCGGCTCCTACTTTGTCTCCTGAAAACAAAGAGATGTTGTTGAACCTTGTAGGAGCAACTGGCCAGAAGAAGCGAAGAGTGGAGGCAATTGTCGAGATCCTTCAGAAGTATACCAACACCGGAGCCGAGGGAAACTCAAAGGATGGTACCGGTGAAGACATCAAAGATGAGGATCAAAGACAAGCAACTCACAGTAGACATGACAAGGAAAGCACGGAAGATAgaggatcgagtgacgaaggtGAAGGTCTGGTCGGTAAGTATACAAAGGTTGATGTacaagggaaaataaaagaagaagaatgttcATTAGAAAGCAGTAGCGGGTCTAGTATAGACCAACAGGATGTAAGTGATGAGGCTGAGGATAATGGGCCGGTCTTAGCACGCTTCAGTGCACTGGACAGTCCAAAAGTTAAATCAACACCATTATCTCCATTAAAAATTAGGTTTCGAACACAATCATATGATGAGGAAGAGGAAGAAGATGGTGgcgatgaggatgatgaggatacTGATGAGAATGGGGTGGAtgcagatgatgatgatgaagatgatgagtCCAGCTAG
Protein Sequence
MSQSEGNDSSLERARFPLYHHSKKNKKKGDKSSMRRHLSDNKMEIEEEVSKGGGSDTDGNIPVASDLPLCVPHLLAPAPVPCQSVITKAWSSPTPASSLQISGPSGTMPSISSRKEVQALPKRNEYTSAAIPKTVVCFICKEWFFSREKFIIHLVMNHRMVHCRHCQEIFETDDMRILHERELHFPLECDICKCTVESTKELAEHYESDHDVPKSKKEDSNFGDHIDGSEKFNSDSSFEPSSDEFLVGSGGENEESDEEEEWKPDVIANLNDEPIEAQIDPTEVECVMNDTSDDEFYDDTSPIQADSEGSDNFISNMQINQEKIEAMIDSLNTGLDEESHEKSAETSTENLRKISTLSSGESQPLTLDTDTVEDQIEKMFQAPSKTTEQLAEPATSNGKVASRESWEAADVLMAIKQEPGTDVDAETKITVRQHIFDFHNNDLMSEPPQRPFAFPCRCCSKKFWHVEERNQHQMDEHSDTIESFFKCYICLQSYTSKVCLNRHVLTTHPGEQRYSPLSYKCKLCLVMFPSVAKMCKHFQDSHPAALVFLCRFCNMTLKTKKTLKTHIKNMHSQARQRECHLCGKMLLSKRAYAIHFRMKHSAISRVGFRCRICQKRFDSKDERKLHYQMDHEGESPYHCTDCGKGFASKSGMYGHRQLHTGTGVSTCGYCGKAFTRKDSYNEHLLIHNGPRHKCPHCPKEFVQRSNLVRHIRIHTGEKPYKCLYCDKCFSDKGACNSHIRVHTREETSSCPYCGQTYSKKQKLKYHIRKHTGEGLITCEICNKQFTNSFALKEHRIIHDRQTQILCRRCGKAFNSEKYLQRHVALVHEPSHMYNCPLCSKAFSLPGRLKAHIMTHTGVKHMKCLLCDKAYSVRKSLRKHLLEKHNVGHDHPHYKRCFYAMSPEEAGLDIPSGSEDEPAIPIFRKQEVKKKVKKPRGTGRRGRPPGSGKKQKQSGDPSLVTSPKRGRGRGRGRGGGRGRGRGRPPKSLSIVASPEPSTSTGRESQRVLRRKPSPKKFEIKQEPDSEEDSDSNNMLSMALQDEKSHSSTDSYEEKITKKRSVGNRKISPMEYHSSAPTLSPENKEMLLNLVGATGQKKRRVEAIVEILQKYTNTGAEGNSKDGTGEDIKDEDQRQATHSRHDKESTEDRGSSDEGEGLVGKYTKVDVQGKIKEEECSLESSSGSSIDQQDVSDEAEDNGPVLARFSALDSPKVKSTPLSPLKIRFRTQSYDEEEEEDGGDEDDEDTDENGVDADDDDEDDESS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01447821;
90% Identity
iTF_01448866;
80% Identity
-