Basic Information

Insect: Tetheella fluctuosa
Gene Symbol: lrrfip2
Assembly: GCA_951216915.1
Location: OX578218.1:12921634-12936897[+]

Transcription Factor Domain

TF Family: LRRFIP
Domain: LRRFIP domain
PFAM: PF09738
TF Group: Unclassified Structure
Description: LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.2 6e+03 -3.1 1.1 241 275 66 101 50 110 0.38

2 3 7.7e-79 2.3e-74 251.1 18.8 1 297 125 410 125 413 0.87

3 3 1 3e+04 -7.1 14.8 1 49 409 456 409 487 0.52

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.2	6e+03	-3.1	1.1	241	275	66	101	50	110	0.38
2	3	7.7e-79	2.3e-74	251.1	18.8	1	297	125	410	125	413	0.87
3	3	1	3e+04	-7.1	14.8	1	49	409	456	409	487	0.52

Sequence Information

Coding Sequence: ATGGGGCATCGATCCGAAGTGGCCACGCCTGATAATAGTGATGAGGAGAGCGGCGACGCCTTTACCGATGGTGATTTCGGTGATTCGGACGAAGAACCtattgtagaaaaaaaagatGATACCAAATCGTCTCATATCCCGATCAATGAGGCTGTAAACGACAAACTTGAAAAGATGAATGATGATTCAATAGATGATTTGGACCAAGCTAAAGACTCGGAGAATCATAAAGTTAACGGACATAAAAGTAGTGAGAATGGACATATAAGTGAGTCAGAAGCTCACACTCAAGCGACAACAGAGTTTAGAAGGGATTCCCACGGCGATCAAAATCCATCAATCGTTGGAATTCTTGGTGACCAACATAACCATGCGGAGCAGCGTCtggcggcgcggcgggcggcgcgtgcGGAGGCGCGGGAGATACGCATGCGCGAGCTGGAGCGGCAGCAGCGCGAACAGGAGGACCATGCTGACAAGGCATATGATATGTATGCAGAAACGgtggggcggcgcggcggcacCCGGCTGGCGGCGCTCAGTCCGGGCGCGGTGCTGTCGCCGCGGCGCAGCTCGGAGGACTCCGCCGACGACGCCTTCAACATCAAGGATCTTAGGCACGAATTGAAAGAAGTAGAGGAGAAGTTCCGCAAGGCGATGATCTTGAACGCTCAACTGGACAACGACAAGGCGGCGCTCGGCTACCAGCTGGAACTGCTCAAGGACAGGATAGAGGAGCTGCACGAGGAGTACGCGCAGTTGCAGCGGGAGCACAAAGAGAAATGCTCAGCTCATGAGCGTTTAAAACGCGAGCACGTATCTCTGGAGCGTGAAGTGGTGCTGGCGCGGGACGCGGTGAGGGCGCGGGAtgcggccgccgccgccgcggggTTCGCCTTCGTGGACgcgggggccgagggggccggGCCGGGGGGCGAGGGGGCCCAGCCAGGGGGCTGTCCCGCGCTCGCGCTCGTGTCGCACCACTCGCAGCAGCTGCTCGATGACGCCGGTGAAGGAACATTAGACGTCCGGTTGCAGAAGTTGCTGAGTTCGAAACAGTCGCTAGAGTCGGAGGTGCGCAAACTGAAGCTGCAGTTGAACGAGGAGCGCGCCGCGAGACAGAACGGGGTGGCCAATCATCACGACCACGAGTATGAGAATGAATTGGAGACGGTGCGCAAGTGCGTGACGGAGGCGAaggggcgggcggcgcgcgcggaGGCGGAGGCGGCGCTGCAGGCGGCCGCCGTGGCGCGCCTCGAGGCGCAGGTGTCGCGGCTGCGCGCGCGCCAGGACCACCAGGACGACCACGAGGAGCAGCTCAAGCAGGAGCGGAGGAAACTGCAGCGAGAGGCAAGAGAAGCCCTCAATCGAGTCGAAGAGTTGGAGACAGAGAACAGCCACTTGACCAAACGTCTTGACAAACTCAAAAACGCCAAGTCAGCACTCCTAAAGGAACTGTGA
Protein Sequence: MGHRSEVATPDNSDEESGDAFTDGDFGDSDEEPIVEKKDDTKSSHIPINEAVNDKLEKMNDDSIDDLDQAKDSENHKVNGHKSSENGHISESEAHTQATTEFRRDSHGDQNPSIVGILGDQHNHAEQRLAARRAARAEAREIRMRELERQQREQEDHADKAYDMYAETVGRRGGTRLAALSPGAVLSPRRSSEDSADDAFNIKDLRHELKEVEEKFRKAMILNAQLDNDKAALGYQLELLKDRIEELHEEYAQLQREHKEKCSAHERLKREHVSLEREVVLARDAVRARDAAAAAAGFAFVDAGAEGAGPGGEGAQPGGCPALALVSHHSQQLLDDAGEGTLDVRLQKLLSSKQSLESEVRKLKLQLNEERAARQNGVANHHDHEYENELETVRKCVTEAKGRAARAEAEAALQAAAVARLEAQVSRLRARQDHQDDHEEQLKQERRKLQREAREALNRVEELETENSHLTKRLDKLKNAKSALLKEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01437066;
90% Identity: iTF_01083346;
80% Identity: -