Sver017516.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Shargacucullia verbasci
Gene Symbol
IKZF1
Assembly
GCA_947562105.1
Location
OX387282.1:10487715-10492106[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.15 11 7.0 3.4 2 22 196 216 195 216 0.95
2 16 0.06 4.6 8.2 2.6 1 23 313 335 313 335 0.95
3 16 0.42 32 5.5 0.3 2 23 469 490 468 490 0.96
4 16 0.00037 0.028 15.2 0.7 2 23 570 591 569 591 0.96
5 16 0.093 7 7.6 0.3 1 23 599 621 599 621 0.97
6 16 0.065 5 8.1 3.6 1 23 657 679 657 679 0.95
7 16 0.00017 0.013 16.2 4.0 1 23 687 709 687 709 0.99
8 16 0.16 12 6.9 1.8 1 23 794 816 794 816 0.98
9 16 8.2 6.2e+02 1.5 0.7 1 19 872 890 872 894 0.90
10 16 1.2 92 4.1 0.0 2 23 901 922 901 922 0.96
11 16 0.015 1.2 10.1 0.9 1 23 989 1011 989 1011 0.94
12 16 0.0038 0.29 12.0 1.1 1 23 1017 1039 1017 1039 0.96
13 16 0.0047 0.36 11.7 2.6 1 23 1129 1151 1129 1151 0.97
14 16 0.00012 0.009 16.7 1.4 1 23 1157 1179 1157 1179 0.99
15 16 0.46 35 5.4 2.4 1 23 1271 1293 1271 1293 0.96
16 16 0.0069 0.52 11.1 5.6 1 23 1304 1326 1304 1326 0.98

Sequence Information

Coding Sequence
ATGGGTCTACAGTACGCAGAAAGAGAAATAGTCAATTGCAAAAGTGATTCCAATGACGGTACATCGTCTGACACGATTACTAAAAAAGATGTTTCGCACATGGCACAAGATGTATACAACCAACTTTCCCCTAACCACAGCGCAGATGAGAAGTTACAAAAACAAAATAGAAAGATTCCCAGACCAATACCACAACTCATACCGTTGAATTCGTCAACCCCTAATCAAAAACAAACATGCTCTGGTGAACCACCAAACAAAAAGTTCAAGGAATCTTTCTCATCTGAAATAGGTGATTCAAATTCAGAAGGTAAAATTGAAGACCTGCCTGGTGATATTACTTTAATTCCTGTAAATAGTAATCCATCACTAAAAGAGACTGCAGGCCGCAAGAAAAATGAATCATTTTTCGACAGGTTAAAAGAAAGACTATTGACAGAAACAGGTGAAGAAGGTTCTCTGATATGCAAAAGTTGTGGATTTGAAAGTAAATGTCTATCAGAACATTCTGTGCATGAGAAAAATTGTTCACCGCAAGCTAACCGGATCAATGCAAACACGACGCTATCAAGTTTAAGTTCAACTCGATGCCAAAATTGCAGACATAGGTGTAAATCTAGTGCAGACTTATACATTCACATGCAAACTTGCGGAAGAAGTGAAAAGATGGAAGACGAAAATAACATTAAAAACCATGATAGTAATGATGAAATCATTCCAATTTATGAAAAAGAGACTGAACCACATCCAATGGAAAATGTCGTTTTCGTTTGGAACAATATTAATCAGGACAGTAGCAAGTTTGATATGCCTCTAGATATAAATATAAACGATGATTGCACTCTTCCAGAAATTCATAGAGGCTTCGATGCTGAGATTGTTGATGAAAATGAAACTATGAATTTGTCCCCAAGTCAAGCTATCGGAAGAAAGGTATTTAAATGTCCACATTGTCCATTTTTCTCCACAACAGCTTCCAGATTTCACGTTCATATTGTGGGTCACTTAAACAAGAAACCGTTTGAGTGTTCCCTCTGTAAATATAAATCTAATTGGAGATGGGATATCACCAAACACATCAAATTGAAATCTGCGAGAGATCCGGAGCATAACGAAGCAAAAGTGTTAATGACTGATGAAACCGGAAGAAGAAACTATAGCAAATATAATAAGTTCTTAGCAATGCCAGTTTTAAATGAAAATGAGTTTCATTACCTGGATCCTAATACATCAGTTGATGGCACAATAGAAATGGATGAATCGTTCAATGAAATCTCAGATGTTATGAATGTACAATTTGAAATGCAACCGCTTAACTTACAGACTCAACACGGCGATGATAAATACGACTTTATTGATAACAGAAGTATGAATGACTTGAAGAAACCCAAGAGAACATTATGGAAATGCAAAAAATGCAATTACAAAGATCCGTCAAAAGAAGCTCTTTTGGAGCATGTTCGTGAACATTCCAGATCGGATGGCATACACGAAGAACCACACAAAGCAGCCATTAACAAGAAACCCGATAACACTCCCGATCCAGCAGATCTGGCATATCGTTGTGGTCATTGCAATCAATTGTCTAATTGGAAACATGTCATCCAGCGCCACTGCCGTTTAAAACACGACGGAGTGATAAAAGTCATAACTACAGTTAAACCAAAACCGGATCCATCAATGAACATCAACGAGATCAACAGCGACACATGCAACAAATGTCCGTACAGAACGAGTGACAAAAAACAACTTATCGCTCACTTACAACAACATCAGCCTTCGCCGAATTCCATATTTAAGTGCTACTTCTGTCCATTCTTCGTTAAAGATGAACCAGAATTAATACAACATCTTCTCCTGCACGGCATCACTGACCCAGAAGATTACATTGCAAAAGCCATGGGAAACAAATCTCCAGGGCCTGAACCGCAAGCACCTGTAACTACATCAACAACTTCCACCAAACGTCACAAATGCACAGAGTGTCCATACGAAACAAACAGTAAGTCACAATTCATGTACCATGAACAATTTCATCGACTTCCAGCAGACACGCCTTATAAATGCCCAGAGTGTAACTACAGCGTATCAAAAAGACACCTGCTACACCAGCACCTCAGGGTTCACGGAATCGCAACCAAAAGAATTGAAACCGAGGCCGAATTAGAGGCATCAACGTCACTACAAAAGAACACAGATCTGAAAGTAGAATTTCAAATTAATTTAGATGAAATACCATATGTTTGGGTCTCGGCAAAGAACGAATTTCATAAAATGTACAAGTGCCGATACTGTTCATATGTAAATTCTCAAAAATGTAAAATTCCAAATCATGAAAAAATCCATTTCATCGTATTCGAAAACAACGATACAACTATTTACAAGTGTTTGGAATGCAAATTTACGTGTGATAACGCCGGCAGACTGGCAGAACATTCCAAATCGCATGGCGAAATATATGGTCGCATTTACTGTCCTGTTGAAGAAGATATTCCCGATGAAGAACAAATTACCAAACTGAGAAAAGTAATAGAAATTGAAAAATCCTCGAATCCGGAAAGTTTTTCTAGAGACGAAGGTTTAGCAAACGAAAACAGAGAAATAAAATTATTATATTTTTGTCAAAAGTGTCCAGCAAGATATTTTGAAGATGGCGAATTACAAGCTCATGACAAGTTTCATGATTTAACATTTTTGAATAGGTGTAAAAGTTGCGAGTTTTCAGTACCCGAGGAAAATGACTTGGCGGCACATATTACTGTCCATACTGATGAATACCACACAAAAACGAAGATGCTTAAATTTATTCACAATTCACATCCTTCGCACAGGGAACCCATGATGGAACTGGTACACTGTCCAACAAGTTCAGAGATCACATGGATAGCTACGGGTCCGAGTAAAGTTGAAAATATCGAAACTACTATGAAAAAGTCAAATGATACAAAACACGTGCCAAAGCAATATTATTGCAAACAATGCCCTGCAAAGTTTTTCAAAAATTCAGCGCTAAGTTATCACTTGGGGCTACATGGAAGTGAAGGAGAGCATAAGTGCAAGAAATGTAATTACGCCGTAAAGAATATTGGAAACTTAGCTAAACACGAATTGTTACACGAAAATGAAAATAAGGCTTCAAATTGCGATTATGAATCTGGTGATGATATGGACTATAAAAATATTCCATTGTCGGGTACAGACTTGTTCCAGAGAAAGACTGAAGCGCAGAAAAGAGTCTTAACCGATAAAGATAAGTTAGTTAAACCGAACGATCATTTTCCGCCTGTACTACAAGCCGATCCACAATTCGGTTATTTGATGCATGGTAATCCAGAATTTATATATCCTACGTACTTGAAAAATGGCCGTCAGAAAGAAAAACGATATAAATGCCACAAGTGCCCTTCAGCATTTGAAAAAAGAGAACAGTATAAAATACATTTATCATTGCATGGTTCCAAACAAAGATATAAATGTGAACTATGCGATTATTCAGTAAAATATTATGCCAACTACGTTCAACATATGAGGAAACATCAAATGAACGACGAAGCACAAGCTGAAAGAAAGAAAGGTAGTACTGACTTTATAGAATCTGAAAATCAAGAAGATGTTAAACAAGATGACAGTAGTGATAATATTAAACTCGCAATAAAAACTATGCCAAAAGGGGCTCCTAGGAGCGATTTCCAACAATTCTCAATAAGTGACCAACAAACCCTCAGACTGTTGCAACGACGACGGTCAATGAATAACTCTGGAAAGGACATGAGTACGTTTGAAAGTTCGCCGACAAAGGAGCGTAAAATGCACATGTGTGTGTTGTGCCCCTATACTAATCAACGTCAAGACTCCTTAAGTAATCATTACAGAAGGCATGGTGACACTGATGTTTTTAACCCAGGCAGCCATAAATGTTCTCACTGTGACTTAGTAGTCGTTCAGTCACATTTCCTCCGGGAACATCTAAAAACGCACTTTAATTACCACAAAACACTTACTCCCGAATGTTTTGTGGCCAATGACGATGTAAGTTTCACCATAACCAAATTGGATGAAGACAGTGAAATTAAAGTTGATCTCAAATTAGACATGCAAAATAAAAGTTTCACATGTAATGGTGACAAGATATTTGTGAGAATTAAAACAGGAGAACTATTGGTAGAATAA
Protein Sequence
MGLQYAEREIVNCKSDSNDGTSSDTITKKDVSHMAQDVYNQLSPNHSADEKLQKQNRKIPRPIPQLIPLNSSTPNQKQTCSGEPPNKKFKESFSSEIGDSNSEGKIEDLPGDITLIPVNSNPSLKETAGRKKNESFFDRLKERLLTETGEEGSLICKSCGFESKCLSEHSVHEKNCSPQANRINANTTLSSLSSTRCQNCRHRCKSSADLYIHMQTCGRSEKMEDENNIKNHDSNDEIIPIYEKETEPHPMENVVFVWNNINQDSSKFDMPLDININDDCTLPEIHRGFDAEIVDENETMNLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAMPVLNENEFHYLDPNTSVDGTIEMDESFNEISDVMNVQFEMQPLNLQTQHGDDKYDFIDNRSMNDLKKPKRTLWKCKKCNYKDPSKEALLEHVREHSRSDGIHEEPHKAAINKKPDNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPSMNINEINSDTCNKCPYRTSDKKQLIAHLQQHQPSPNSIFKCYFCPFFVKDEPELIQHLLLHGITDPEDYIAKAMGNKSPGPEPQAPVTTSTTSTKRHKCTECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIATKRIETEAELEASTSLQKNTDLKVEFQINLDEIPYVWVSAKNEFHKMYKCRYCSYVNSQKCKIPNHEKIHFIVFENNDTTIYKCLECKFTCDNAGRLAEHSKSHGEIYGRIYCPVEEDIPDEEQITKLRKVIEIEKSSNPESFSRDEGLANENREIKLLYFCQKCPARYFEDGELQAHDKFHDLTFLNRCKSCEFSVPEENDLAAHITVHTDEYHTKTKMLKFIHNSHPSHREPMMELVHCPTSSEITWIATGPSKVENIETTMKKSNDTKHVPKQYYCKQCPAKFFKNSALSYHLGLHGSEGEHKCKKCNYAVKNIGNLAKHELLHENENKASNCDYESGDDMDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKGSTDFIESENQEDVKQDDSSDNIKLAIKTMPKGAPRSDFQQFSISDQQTLRLLQRRRSMNNSGKDMSTFESSPTKERKMHMCVLCPYTNQRQDSLSNHYRRHGDTDVFNPGSHKCSHCDLVVVQSHFLREHLKTHFNYHKTLTPECFVANDDVSFTITKLDEDSEIKVDLKLDMQNKSFTCNGDKIFVRIKTGELLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00050427; iTF_00018644; iTF_01222046; iTF_00185711; iTF_00186705;
90% Identity
iTF_00050427;
80% Identity
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