Rmai001448.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Rhopalosiphum maidis
Gene Symbol
-
Assembly
GCA_003676215.3
Location
NC:70607707-70617557[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.8e-14 1.6e-11 43.1 0.0 9 72 149 218 143 221 0.95
2 2 0.5 4.5e+02 -0.0 0.0 29 57 347 375 328 392 0.69

Sequence Information

Coding Sequence
ATGAGTAATTTAATGgaaaCCAATAATCTTTTAAACCTAGAAGCACGTTTTATTGGATTTGATATTGATGATGaagtattgataataattgaaaataagaaaaaatCATTAAAAATGGAACTTAGTAAAGAAACAGGTGAACCTATGGAAGTAGACGAGCCAACTGACAGTCCAtccattgttaataataatcatgttaataaaaagaaacaatCTAAATCAAGTAtatCATCACCAGAACCTAATGATGTAAAGAATAATCGGAGTAATAAGAGGCATAAGAAAGACAACACACACAGTGATACCTTAGAATCTTTGGAATTACATGTTCCGCCTTCTTTAGaaCTTACTACTCCTACATTCAACTTAACTTCTTCCAACACTAGAACGCGCCGTAGTACAggaagaaaaattaatgttgaTATTACTGACGCTATTTTTAAACTTCCATTTGAGCAtggatGGAAACGAGAATTAGTATATAGGACATCAGGTGAATCTACTGTTCTCAATCGGGCAAATAGAAGTggtgatgtatattattattctccaAATAACCGAAAACTACGATCATTACGAGAAATTCAGGAACAGTTGGATATCTCATCTGATAAAACTTCTCTTACTATCGacagttttacttttttaaaacaaccaATTGGCATGAATGATAGATCAAAAGAACTGATCAGAGATGCAAATTCTAAATTAGCTAAGgaaGAATCTTTTGTTGGTGTTGCTGTTCgaccaaaaaaatctaaaacaccTGTACAGCGCCCACCATTTGATTATGAATTGTCAGatgatgaaaacaaaaaatctgctagtaaaatgaaaattgtttttaaaaatgcaaaaacttCCTCAAGATCAAGATCCAAAaaaggGAATTCAGAATCAATGAATACATCTTCATCCACACCTGAATACATATCTGAAGACTGGCAAGCTATTCAATCTAGTGTGTCACCAAAAGTTTCTCCTAAACTTgagaatattgatataaatactaCAACCATTAAAAGACGGTTGTCAACATCAGATGGGGAAATCATCATGCAAGCTCCTTGTGGAATTCGGTGCCCTAATAATGACGAACCTGCTTCTTTAATGTGCACTCAATGTCTGGTCTACTATCATCCAGCATGTGTCAATATAAATGCTCAGTTAAAGATTGTTGGTTATGTATGTTTAaACTGTCGATCTATTATGCAACAAAGAAATACACGTGTACAGTCATCTCATACTGTGGTTGTGGGTGCTACTGAACCAGAGCAACTACGCGTTGAACCGATTCGTATAAGACAAGTTCATCAAGCTTCAGATACGCCTAATTTCTTTATTGATAGAACGCcaatttctaaaattgaagAACCACATGAAATTGATGAATATAGAGATGAAAATGaccttgatattataaatactgttaTATGTCAaggaaatgtatacaaaactaCAATGGTTGATGGCAGTTTTCACGAACAGTATGTTTATGAGATGAAACAAACACGAGGGCCTAGTTTGATGACTTGTGTTATTCAAGAGCCCAAAAATTTGGATgaGAATTCTGAAATGAACGGttcatttaaagaaattacaaCTACTTTTACATCCATGCAATCATTTAACTACATGGTTAAAGCATTGAGacacgtttttaaatatttaaaaacacatgAGCTTTTATCCGCTTCTAGAGTATGTACCGCGTGGCATATAATTGCAATGAACAAGTTTTTAtggcAAAATGttcgtttaaaaaattctatggTCTATGACTGGGAAAGGTTTGTAGACTCTATTGATCATCAAAGAACTGATACTTTAGATACTAGACGAATGTTGATACCTATAAAAGTTGACGAATTCGAAAATTTTTGGTTGCATTTTTCCAAAGCAATGAAAAGAGCACAGAAgttaaaattcattgaattgtATAGATGTCCTACCCATGTAGTTGaagatattatttactcaTTACCTCAAATTGAAGTACTTAATGCAACttcaataaaaaatccaAATGTAACAAAAGAGGCGAAAAATCCCAATGATTTTATGGCCCTaagcttaaattatttaggccAAATGACAAAGCTCACCGAGTTAAGACTAAAAGGTTTAACTGGAATCAAATTAACGTCATTGCcatcatttgaaaatttaataaatttaaataaattttcattAACTTCTATAAAATCATTTCCAAAAGACATCTATCAGAGTTTGGATACTATTACTGAAAACATAGAATTTTTGGAAATTGGCGATTGTGATTGCCTATCAAAAGATTTTGCTGTGTCATTAAAAAGATTTGTCAATTTGAAATCGCTGAGATTGGAAAATTGTTGCGGTAAATGGGACAGTTGTGCACAAGACGTTTTTACTGCTATTAGGGGTCTTGAAAAGCTCACTATTCTCGAATTGGTCAACATAGAATTCAGTAATTGTGTTGAAGATGAATTGGAAAAATGTATTGGTATTAAAGCTTTACTGATTATTCCTGCTTATGTGAGCCAatctgCAACTACCAACTGCCACTTGATTGACTGCCTCAAGAAACTCTCCAAGACATTAACACACTTGGTTTGGGGATTGACTCATGAATTACTTCGCGTTACTGACTTATTTATAACTCAATATCAACAAAACCAGCATAgtattggttataatttagaattatcCCATACCAAAGAAACGACCAACAACATACCTATACTAAGGACAAGAAAACCAAGACAGCGACCAGGAGAAGAGTCAGCTCCCGAAAAGGACAAGGACAAAGACAAATCAGATAACGTTGATATACTTTCAGTTCCTGCTCTAGAAAAATTGCTAGATACTATGATGCCTGATGCTAAAACTAGGGTAATTAAGGTTCCCTTTTCAGGAACAGTTAGAGTTTATTTGAGTGAACAGTTTAATGATCTTTGA
Protein Sequence
MSNLMETNNLLNLEARFIGFDIDDEVLIIIENKKKSLKMELSKETGEPMEVDEPTDSPSIVNNNHVNKKKQSKSSISSPEPNDVKNNRSNKRHKKDNTHSDTLESLELHVPPSLELTTPTFNLTSSNTRTRRSTGRKINVDITDAIFKLPFEHGWKRELVYRTSGESTVLNRANRSGDVYYYSPNNRKLRSLREIQEQLDISSDKTSLTIDSFTFLKQPIGMNDRSKELIRDANSKLAKEESFVGVAVRPKKSKTPVQRPPFDYELSDDENKKSASKMKIVFKNAKTSSRSRSKKGNSESMNTSSSTPEYISEDWQAIQSSVSPKVSPKLENIDINTTTIKRRLSTSDGEIIMQAPCGIRCPNNDEPASLMCTQCLVYYHPACVNINAQLKIVGYVCLNCRSIMQQRNTRVQSSHTVVVGATEPEQLRVEPIRIRQVHQASDTPNFFIDRTPISKIEEPHEIDEYRDENDLDIINTVICQGNVYKTTMVDGSFHEQYVYEMKQTRGPSLMTCVIQEPKNLDENSEMNGSFKEITTTFTSMQSFNYMVKALRHVFKYLKTHELLSASRVCTAWHIIAMNKFLWQNVRLKNSMVYDWERFVDSIDHQRTDTLDTRRMLIPIKVDEFENFWLHFSKAMKRAQKLKFIELYRCPTHVVEDIIYSLPQIEVLNATSIKNPNVTKEAKNPNDFMALSLNYLGQMTKLTELRLKGLTGIKLTSLPSFENLINLNKFSLTSIKSFPKDIYQSLDTITENIEFLEIGDCDCLSKDFAVSLKRFVNLKSLRLENCCGKWDSCAQDVFTAIRGLEKLTILELVNIEFSNCVEDELEKCIGIKALLIIPAYVSQSATTNCHLIDCLKKLSKTLTHLVWGLTHELLRVTDLFITQYQQNQHSIGYNLELSHTKETTNNIPILRTRKPRQRPGEESAPEKDKDKDKSDNVDILSVPALEKLLDTMMPDAKTRVIKVPFSGTVRVYLSEQFNDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00940496;
90% Identity
iTF_01328635;
80% Identity
-