Rros010350.1
Basic Information
- Insect
- Rhingia rostrata
- Gene Symbol
- Rfx2
- Assembly
- GCA_949824845.1
- Location
- OX463756.1:45421561-45446722[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 4.7e-38 7e-34 117.0 0.2 3 78 185 260 183 261 0.97 2 2 2 3e+04 -3.8 0.0 25 41 634 651 632 655 0.75
Sequence Information
- Coding Sequence
- ATGCATCAACCGGATTTCCTGTCACGAATCTACCAATTTTCCATCGAGCACAAGAAGCACGGCGATATGTATAGGCGACACAACAATCTGTCCTACTGCGGtgTTTCCACGCAGGACACCGTCGGTGGTCAGAATTACCAAGTGCAATATGTCGACACAGAGTTGTACCACAGTAACTCTAGCCAATCTCAGATGGCATATCCGTTTTGTCCAGTTGGTGACTATCAAACTAGTAGCCAAACCTACTACTCAACGACGGGTAACTACTCTACAACGAACACACCCCCATCGCATGCTTCCGGGTTGCCTTATTTAGTTCCTGGCGAGGAGACACTTCTCCTTAACTCCTCGTCTCAGAGTCGCGACTCACCACCGAGTTTAACCGAAGTGACTTATTTGCAAGATGCACAAACTCCAACATCCACCACCCCGTCGAATATAGGTTCATCCATAACCGGTAGTGGTGGTGTCAATGGCAGCGTTGGCAGTGGGAATGGTGGACTCAACATTGGGGATACAGCCAACCTCGCAAATGCCAACAAAATTGCCTCGGCTACGATAAAGTGGCTTACACGTAACTACGAAACGGCAGAAGGGGTGAGTCTGCCCCGCTCGACCCTATACAATCACTACATGCACCACTGTAATGAGAACAAATCGGAACCAGTGAATGCTGCCAGCTTCGGAAAGTTGATTCGTTCGGTGTTCTCGGGATTGCGAACCCGTCGGTTGGGCACTCGTGGAAACTCAAAGTATCACTACTATGGCATTCGTATAAAACCCGGATCCACTCTATCGCACACAATGGAGGATAAGCCAGGTCAAGCGTTTTCCGGACAAAATTCAAATGGTGGTGCAACACTTAACGGCCTCGGTGGTGGTAGTGGTGTTGGCGGTGGCGGTATTGGTGGTGGTAGTGGCTCAAATCTCGGAGGCGGAAGTTTAAGCAAAGGCATGAAAAAGCATGGTGTCAAACCGGAAACATATGAAGCTTGCTCGCAGTATTTGGGCGATGGATCGGCTTGTATTCCAATCTTTCCCCACATCAATCTGGACAACACTTTCAACAACGAACTAACCCTAGAGGATGTAGAAACATTTCGCTCTATGTATCGTGAACATTGTGAATCATTCCTAGATGCTGTACTTAATTTGGAATTCGGTACAATCGAATACCTGTGGCGTGATTTTTGGCGCTCCTCCGACAATAACAACCTCGATGAATGTGAGGAAGAGAAATACTTATCCAAGACAAAGTTGTACTTGCTTTGCCACTGCAGTGGAGTACAGAAATTCATCAAACAGGTCGATTATCAATTCTATCAAAACATGGTTGATGTACTAATCCCGGACGTGTTACGTTCCATTCCAAATACCCTAACTCAAGCCATTcgcaattttgccaaaaatctgGAAATTTGGTTGTGTGAATCGATGGTGGGAGTGCCAGAACGGGTGGTTCAAATCAAATCATCAGCTGTGTCGGCATTTTGTCAAACCCTACGACGCTATACTTCGCTCAACCACCTAGCTCAAGCTGCACGGGCTGTGCTGCAGAATAATTCTCAAATTGCACAGATGTTGAACGATCTGAATCGTGTAGACTTCCATAACGTTCAGGAACAGGCTGCCTGGGTATGTCAATGCGATGCCTCAATTGTGCAACGTCTGGAGAATGATTTTAAAGCAGCTTTGCAACAGCAAAACAGCCTTGAACAGTGGGCCAGTTGGCTACGTTTGGTTGTCGATTCGGCACTGGAAGAATATCGTGACAAACCAAATTATGCCAAAGCTGCACGCCAATTCCTACTCAAGTGGAGCTTCTACAGCTCGATGGTCATTCGGGATTTGACTTTACGATCGGCGTCCAGCTTTGGTAGTTTCCATCTGATTCGTTTACTTTACGATGAGTACATGTTCTTTCTGGTTGAACATAAAGTCGCTGAAGCGCTtcagaagactgcaatcgccgtTATTAGCGATAGAATGCAAAAAGATACCGAGTTTGAATTTGATTATCAACTGGAATTTATCGACAGCACAGAAACAGATACCATTAAACGCATGAAGCATGAATGA
- Protein Sequence
- MHQPDFLSRIYQFSIEHKKHGDMYRRHNNLSYCGVSTQDTVGGQNYQVQYVDTELYHSNSSQSQMAYPFCPVGDYQTSSQTYYSTTGNYSTTNTPPSHASGLPYLVPGEETLLLNSSSQSRDSPPSLTEVTYLQDAQTPTSTTPSNIGSSITGSGGVNGSVGSGNGGLNIGDTANLANANKIASATIKWLTRNYETAEGVSLPRSTLYNHYMHHCNENKSEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSTLSHTMEDKPGQAFSGQNSNGGATLNGLGGGSGVGGGGIGGGSGSNLGGGSLSKGMKKHGVKPETYEACSQYLGDGSACIPIFPHINLDNTFNNELTLEDVETFRSMYREHCESFLDAVLNLEFGTIEYLWRDFWRSSDNNNLDECEEEKYLSKTKLYLLCHCSGVQKFIKQVDYQFYQNMVDVLIPDVLRSIPNTLTQAIRNFAKNLEIWLCESMVGVPERVVQIKSSAVSAFCQTLRRYTSLNHLAQAARAVLQNNSQIAQMLNDLNRVDFHNVQEQAAWVCQCDASIVQRLENDFKAALQQQNSLEQWASWLRLVVDSALEEYRDKPNYAKAARQFLLKWSFYSSMVIRDLTLRSASSFGSFHLIRLLYDEYMFFLVEHKVAEALQKTAIAVISDRMQKDTEFEFDYQLEFIDSTETDTIKRMKHE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00426856;
- 90% Identity
- iTF_00240402;
- 80% Identity
- -