Basic Information

Gene Symbol
-
Assembly
GCA_014839585.1
Location
QVOB01005083.1:13562-16223[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.3e-05 0.0014 19.3 4.4 2 23 284 305 283 305 0.97
2 15 6.6e-05 0.0075 17.1 0.7 2 23 311 332 310 332 0.96
3 15 2.7e-05 0.003 18.3 0.9 2 23 421 442 420 442 0.97
4 15 1.7e-05 0.0019 18.9 4.7 1 23 448 470 448 471 0.96
5 15 2.8e-05 0.0031 18.2 0.2 1 23 476 498 476 498 0.98
6 15 5.8e-07 6.6e-05 23.5 0.5 1 23 516 538 516 538 0.98
7 15 1e-06 0.00012 22.7 1.2 1 23 544 566 544 566 0.97
8 15 7.8e-06 0.00088 20.0 2.4 1 23 572 594 572 594 0.98
9 15 0.0011 0.12 13.2 0.2 1 23 600 622 600 622 0.99
10 15 7.1e-05 0.008 17.0 0.2 3 23 630 651 629 651 0.96
11 15 1.5e-05 0.0017 19.0 1.3 1 23 657 679 657 679 0.98
12 15 0.00034 0.038 14.8 4.7 1 23 685 707 685 707 0.98
13 15 4.3e-06 0.00049 20.8 0.4 1 23 713 736 713 736 0.97
14 15 1.5e-06 0.00017 22.2 0.6 1 23 742 764 742 764 0.97
15 15 3.7e-06 0.00042 21.0 5.0 1 23 770 792 770 792 0.99

Sequence Information

Coding Sequence
ATGAACAAAGATATGCCATTGAGCATAGAATGGATTCCAAAAGATGCACACAATTCTCTGGATCATTTTCTGCCGGGAGATCGAGATGGGCGCAATGTTGTATTTCTAAAACAAGAACCTGAGTTCTTGGAAAAAGCGTTAAATACACAAACTTTGAAAAACATGCTTGTTACCATGCAAGTCCCCGAATCTAAGGACGAAGATGAGGTTGAACAACAAAACTGTCAGGAAGCATCAGCAACTCAATGTCGAACAGAATCCCCCAAAAAGACGCCAGAACAATTAACTGAGACTTCTAAGAAATCGTACAACAAAGCTCGCATTGACTTTGCCGAACAAGTTGTGCGTGAACTGCGTTCACTGTGCAAGAATTTCTTCATATTACACGGGGAGTTGCCTAAATCCGAAGTCAGCTGCAGGGATTTTAAGAGTTTGCTCGAGTTCTGGATGAGGGAGAATTCGACCAGAATCTGGTGGGAGGGTTTGAATTTCGTGCAGATGCTTCATAATACGACGTATCACTGTCCGAATGGCAGAGTTCCGTGTGATATGTTGTTTGGACGAAATGTACGCGATAAGTTTCAAAATATCTGCGCGGAAAAGAATACGGAGAATGTGTGGACGGAAGAAAACTGGATCGAGAGTTCGTCGATCGATTCCTTATCGGTGGTTCGTGAGGAAAATGAAAACATACAAGAAGCACAAAGTCAAAATGACAATGTAAACGGTTTTAGTTTCGTCGATGTAAAACATGAAGCTCTCGTGAGCAATAAGCGCAGAACGGATTCGCAATGTACGGATGATGAAACAGACGCGAGAATCGAATCGAAAAGTAACGATAACGCTCTCAAGTGCAAATATTGTCAGAAACAATACGCGAGACTCGGACATTACAAAAATCACATGAGGACTCACAGAGCAGAACAACTGCAATGTAAGCTATGCGACAAAAGTTTTAGAGTTTCGAGATTGTACGAGAAGCACGTTGCGTCACACGGACAGGACAAATTAGATAACAAGACAGAAGTCGATGAAAATATCGAAAGCAACGGCGACGCGTTAACGGCCGTACTTAAGGAGGAAAATAGTCAAGCGAAAACACACGAAATATCCAAGATAGCGAATGAAGATGATCGTGACACGTCATTGATTACGAAAGACTTCTGTGATAAAATCGCTGAGAACTCGAGTCAAACCGTAAGACGAAAGTTGTCCGGAGCGGAAAGCAGCGTCCGCGTGTCGAAGGCGCAATCGCCTCTGGAATGTACATACTGCAAGCAGAAGTTCAGCTTTCCGAGCGTGCTGGTAAGGCACTTGCGGTCGCACACAAATGAGCGACCGTACGTATGCAAGGTGTGCAACAAGAGCTTCAAACAACTGGGACATCTGAGCCAACACTCTCTGACGCATCACGATTATCGCTCGTTCCAGTGCGCGGTTTGCGGTGTGAAATTCGAGTCGCTGGATTCTCTGAAGAAACACGCGAGCACGCACGAGGGCGAGCATGGTGCAATGACAATGCCCAGGATTCGCGAGTATCGCGTGTTCGAGTGCGACACCTGCAAGAAGGTGTTCGCGACGAAGAGCGTCTTGGAGCGGCACATACTCACGCACACGCAGGAACGCCAATACGATTGTAAAGTATGCGGCAAACGCTTCAAGCAGGCCGGCCATGTGAAATCGCACATGCTGATACACACCGGCGAGCGTCGCTTCCAGTGCACCGTTTGCTCGAAGCGCTTCAGCCTGTCAAACTCCCTGAAGAAGCACATGTACGTGCACAATGGCGAGAAGCCGTATCAGTGCGACGTGTGCGGCGCGCGGTTTCTGGAGAAGCGCAATCTCAACGGCCACCTGCTTACGCACACCAACGAGCGTCCGCACGGTTGCAAGATATGCGGCAAACGTTACACCCTGGCCGATACTCTGCGACGTCACGTGAGCGTCGCGCACAAGGACGGTCGTACTTATCAGTGCGAGATCTGCGCGAAGATGTTCAAGCAGCTCGCCCATCTGTCGGTGCACAAAAAGGTCCACAACGACGAACGGCCGTTTCAATGTCACTTGTGCGAGAAGAATTTCAAACACAAAAACGTGCTCAAGTCGCATCTGGCGATTCACGCAAACGTACGGCCGTTCGAGTGTGATGTGTGCAAAGCCACCTTCGTGAGGAAGACGAACTTGCAGACGCACATCTCGTCCGCACACATGAACGAGCGTCCGTATGTGTGCACTATCTGCGGCAAACGTTTCAAACAGATTAGCCATTTAAACGGCCACGTGATTGTGCACAGCAATCTGATGCCCTACAAATGTGACTTCTGCGATCGTCGATGCAATCGACTCGACAATCTGAAGAAGCACATGCGTCTTCATACGAAAAACAAAGAGTGA
Protein Sequence
MNKDMPLSIEWIPKDAHNSLDHFLPGDRDGRNVVFLKQEPEFLEKALNTQTLKNMLVTMQVPESKDEDEVEQQNCQEASATQCRTESPKKTPEQLTETSKKSYNKARIDFAEQVVRELRSLCKNFFILHGELPKSEVSCRDFKSLLEFWMRENSTRIWWEGLNFVQMLHNTTYHCPNGRVPCDMLFGRNVRDKFQNICAEKNTENVWTEENWIESSSIDSLSVVREENENIQEAQSQNDNVNGFSFVDVKHEALVSNKRRTDSQCTDDETDARIESKSNDNALKCKYCQKQYARLGHYKNHMRTHRAEQLQCKLCDKSFRVSRLYEKHVASHGQDKLDNKTEVDENIESNGDALTAVLKEENSQAKTHEISKIANEDDRDTSLITKDFCDKIAENSSQTVRRKLSGAESSVRVSKAQSPLECTYCKQKFSFPSVLVRHLRSHTNERPYVCKVCNKSFKQLGHLSQHSLTHHDYRSFQCAVCGVKFESLDSLKKHASTHEGEHGAMTMPRIREYRVFECDTCKKVFATKSVLERHILTHTQERQYDCKVCGKRFKQAGHVKSHMLIHTGERRFQCTVCSKRFSLSNSLKKHMYVHNGEKPYQCDVCGARFLEKRNLNGHLLTHTNERPHGCKICGKRYTLADTLRRHVSVAHKDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHISSAHMNERPYVCTICGKRFKQISHLNGHVIVHSNLMPYKCDFCDRRCNRLDNLKKHMRLHTKNKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
-
80% Identity
-