Basic Information

Gene Symbol
Hivep2
Assembly
GCA_951394005.1
Location
OX596077.1:35113717-35116633[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0054 42 5.4 0.0 27 52 2 27 1 29 0.90
2 4 5.4e-08 0.00042 21.5 0.1 21 45 30 54 24 58 0.84
3 4 9.1e-05 0.72 11.1 0.5 19 48 58 87 54 91 0.93
4 4 0.41 3.2e+03 -0.6 0.0 21 44 89 112 85 120 0.74

Sequence Information

Coding Sequence
ATGTGCGATATTTGCGGCAACACGTTCAAAAGTAAATTTACtcttaaaaaacacattgaatATCAACATTCGGAAAATCCGCGAAAGGATAAAGAACCCCAACAATGTCCCATTTGTTATAAGGTGTTAAGAGGCCACAAAGGTCTTAGGGCTCATATGAGTAATATACATGCTGAAAGTGAACAGGAACATCGTTGCAAAATTTGTAATCACGTATCGACAACAGCTAAAGGTTTGCGTGTTCATGAGATATTTCGTCATGAGAAGGAGAGAAAACATAAGTGTTCGTTGTGTGATAAAGCATTTAAGAGGCCATTGGATTTGAAAGAACATATGGCCACACATACGGGCGAGCCTTTGTATACTTGTGTGAATTGTggcaaaacatttaaatctaaaGCGAATATGTTTCATCATCGTCGTCGTTTTCATAGGGCCGAATGGATTGCTGATCGTACAAAACCacctaaagaaaaatattcaagAAATTAA
Protein Sequence
MCDICGNTFKSKFTLKKHIEYQHSENPRKDKEPQQCPICYKVLRGHKGLRAHMSNIHAESEQEHRCKICNHVSTTAKGLRVHEIFRHEKERKHKCSLCDKAFKRPLDLKEHMATHTGEPLYTCVNCGKTFKSKANMFHHRRRFHRAEWIADRTKPPKEKYSRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00742432;
90% Identity
iTF_00655751;
80% Identity
iTF_01261371;