Basic Information

Gene Symbol
Hivep2
Assembly
GCA_932527255.1
Location
CAKOBP010000060.1:438755-441714[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0062 24 5.2 0.0 27 52 2 27 1 29 0.90
2 4 1.2e-07 0.00045 20.4 0.1 22 46 31 55 27 59 0.88
3 4 0.00048 1.9 8.8 0.4 20 48 59 87 55 91 0.92
4 4 0.37 1.4e+03 -0.4 0.0 20 44 88 112 85 119 0.74

Sequence Information

Coding Sequence
ATGTGCGATATTTGCGGCATAACGTTTAAAAGTAAATTTGCTCTTAAAAAGCACATCGAATACCATCATTCCGGCAACCCCAAAAAGGATAAAGAACCTCAAGCGTGTCCAGTGTGTTACAAAGTTTTGAGGGGTCACAAAGGGCTCAGGGCGCACATGCAAAACATACACGACAACAGCGACCAGGAACATCGTTGCAAAATTTGTAACCACGTCTCGACAACGGCGAAGGGGTTGCGCGTTCATGAGATTTTTCGACACGAAAAGGAAAGAAACCACAAGTGTTCTTTGTGCGAGAAAGCGTTTAAGAGGCCTTTAGATTTGAAAGAACACATGGCCACTCATACAGGCGAACCGCTGTATACTTGTGTAAATTGTGGCAAAACGTTCAAATCGAAAGCGAATATGTTTCATCATCGCAGACGGTTTCATCGCACCGAATGGATAGCCGATCGCACTAAGCCGCCTAAAGAGAAATATTCAAGAAACTAA
Protein Sequence
MCDICGITFKSKFALKKHIEYHHSGNPKKDKEPQACPVCYKVLRGHKGLRAHMQNIHDNSDQEHRCKICNHVSTTAKGLRVHEIFRHEKERNHKCSLCEKAFKRPLDLKEHMATHTGEPLYTCVNCGKTFKSKANMFHHRRRFHRTEWIADRTKPPKEKYSRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00742432;
80% Identity
-