Pper021254.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Priocnemis perturbator
Gene Symbol
topi
Assembly
GCA_963942575.1
Location
OZ012656.1:10433212-10435476[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.049 4.9 8.3 2.4 1 23 251 273 251 273 0.95
2 16 0.27 27 5.9 1.6 2 23 280 302 279 302 0.95
3 16 0.0014 0.14 13.1 0.3 2 21 309 328 308 329 0.92
4 16 1.1e-05 0.0011 19.8 0.8 1 23 336 358 336 358 0.97
5 16 7e-06 0.0007 20.4 2.8 1 23 364 386 364 386 0.96
6 16 0.072 7.2 7.7 2.2 2 23 398 419 397 419 0.94
7 16 0.002 0.2 12.7 4.0 1 23 435 457 435 457 0.97
8 16 0.046 4.5 8.4 0.2 1 23 463 485 463 485 0.95
9 16 0.6 59 4.9 1.3 1 23 495 518 495 518 0.94
10 16 0.055 5.5 8.1 0.0 1 21 532 552 532 553 0.92
11 16 0.0053 0.52 11.3 0.1 1 23 558 580 558 580 0.98
12 16 2.4e-06 0.00023 21.9 3.1 1 23 586 608 586 608 0.98
13 16 0.00015 0.015 16.2 0.4 1 23 614 637 614 637 0.97
14 16 0.057 5.7 8.1 0.7 1 23 643 665 643 665 0.89
15 16 3.8e-07 3.7e-05 24.4 2.2 1 23 671 693 671 693 0.99
16 16 7.2e-06 0.00072 20.3 4.9 1 23 699 722 699 722 0.96

Sequence Information

Coding Sequence
ATGGCACAGATACTGAAGACAGAATCCCTTAGTACATTAAGTGATAGAGAGGATGACATTGATGACCTCGATGGATCAGTTGTTTGGTCCCAAGAAGAACCACTTTCATCCAGTGAAATATTGGAACTTGAACCAAATAGTACCACAAAGGAGAATAATTTTATTTCCCTCTGTCGTCTATGCGCTGGGCAGGCAATCAATCCAGTATACATTTATTCAGACTTCGGGGAGTCCATGAGATTGGCGAATAAAATGAACACTTGCTTAAGCGTAAAGGTGAGAAGGACAGATCCATTGCCGAAACAACTTTGCATTGCGTGTGTTGAGAAGATAAATTGGTGTGATGAGTTTGACATGCAATGTATCAAGGCAGAGGAGATTCTCCTGACAATGTTGAAAGAGAAGCAAACGTTTGATGTTTCCGAACTAGTACCAGCTGATACAGTAAATGATTTGAAGTCATGTCCATTGTGTTTAGAGGGGCATATGACTACTTGCGAAGAAGCCATACAAGATCCAGATGACAAAGAGTTATATGATAGCGACGTCGTCTTGGACAGCAGCGACGAAGAGAAAATATTTAATGAAGTCAAACTCGATAATGAAACGGGTAACAAAGCGATCATGTTACAATGTTTAGGCAACAAACAGAAGTACCTAAAATGCGGAGCGTGCATGAATCTCTATCACACGAAAGAGACTCTGGACGGTCACAAGTGTAAACCGAACATTCAGAACACGTCGAAGCCGTACAAATGCGACACATGCAACGTCACCTTCACTTTCGAGGAACGACTCAACTTCCACATGCAATTTCATGAGGGCGCGAAGGCGTTATATTGCGAGACCTGCAAGATCACGTTCGGCAAGGAATTGAAGCTGTTCTACCATTACAAAAGGTACCATTGCCAGGACGTTACTGTGTCTTGCCTGCAGTGTGGGAAATTGTTTGAAAATCAATCGGAGCTTCGTCTGCACGTGTGCGTCGACGGTAAGACGAGGCCTCACGTCTGCGAGGTCTGCAATAAAGGATTCTCCGACGGGTATACCTTGAAACGACACATAGTCACACACCTACCCGAGAAACCGTACAAGTGCTCGCAGTGTTCGAAGAGCTTCACGCAGAAGTCTCGACTGAACAAGCACACGGCCGGACACGGTGTCGTTATAGAGAACAGTCAGAGCGTTTGGAAGTGCGTACAGTGCGGCGAAGTTTTCAATTCGTGCGAGGACGCCTGTACCCATTTCGGGACGCACAAGGACAAGGTCACGCTGATCGAACAGCAGCTCACCTCAAAGGTATACCACTGCGAGTTTTGCAACAGCTACTTCACCGACGTTAGCAACCTAAAGACCCATCAGAATCAACACGTCGTTGAAAAACCGTACAGCTGCAACGTGTGCTCCACCGTGTACAAGTCCTTCGCCGAGGCCATTCTGCATTGGAAGGAGCACGCGAGGGTGTTCAAGATATTGACAGTATTCTTATGCGACGTCTGCAGCAAGGACATGAAAGAGCTCTCGCTGCTTTACAAGCACAAGCAGAAGAGGCATCAGTACGCGGCTAGGAAATCGGACACCGGAACCGCGAAGTTCATTTGCGAACTTTGCGGGAACGTCTTTGATAAGAAGGAAGAGATACAGGAGCATGGGCGTGACCAGTGCTCCAAGTTTCCCTGCGACATTTGCGGTAGCCTCTTACCCACAGCGAACTCTCTGAACGCGCACAAGAGACGGCACAGTGGTCTGCGACCTTACGTCTGCAACATTTGCGGCAAGAGCTACACTCAGTCGAGTCATATGTGGACGCACAAGAGATTTCACATGGGCGTGAAGCCGTATGCTTGCGAGTATTGCGATCAGCGGTTCACCATAAAGCCCGATCTGGCCGATCACACGAGGAAGAAGCACACTAGGGAGAGGCCGTTCAAGTGCGACGTCTGCAATAAGGCCTTCCTCACTGGCTCAGTTTTCTATCAACATCGTCTGATACACAGGGGCGATCGCAGGTACAAATGTCACTATTGTGAGAAGGCTTTCACCAGAACGGAGGCGTTGAATAATCACATCAAGATTCATACGGGAGAGAAGCCGCATGCTTGCGACGTGTGCGGAAGATGCTTCAGGCAGAAAGGCGACATGCGGAAGCACAGGCGAACGCAGCACAGTGCCAAGCCAGAATTGCACTCCTAG
Protein Sequence
MAQILKTESLSTLSDREDDIDDLDGSVVWSQEEPLSSSEILELEPNSTTKENNFISLCRLCAGQAINPVYIYSDFGESMRLANKMNTCLSVKVRRTDPLPKQLCIACVEKINWCDEFDMQCIKAEEILLTMLKEKQTFDVSELVPADTVNDLKSCPLCLEGHMTTCEEAIQDPDDKELYDSDVVLDSSDEEKIFNEVKLDNETGNKAIMLQCLGNKQKYLKCGACMNLYHTKETLDGHKCKPNIQNTSKPYKCDTCNVTFTFEERLNFHMQFHEGAKALYCETCKITFGKELKLFYHYKRYHCQDVTVSCLQCGKLFENQSELRLHVCVDGKTRPHVCEVCNKGFSDGYTLKRHIVTHLPEKPYKCSQCSKSFTQKSRLNKHTAGHGVVIENSQSVWKCVQCGEVFNSCEDACTHFGTHKDKVTLIEQQLTSKVYHCEFCNSYFTDVSNLKTHQNQHVVEKPYSCNVCSTVYKSFAEAILHWKEHARVFKILTVFLCDVCSKDMKELSLLYKHKQKRHQYAARKSDTGTAKFICELCGNVFDKKEEIQEHGRDQCSKFPCDICGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHSAKPELHS