Crja001137.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cephus rjabovi
Gene Symbol
topi
Assembly
GCA_030264185.1
Location
JASCRG010000072.1:1797496-1799768[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.13 11 7.1 2.0 1 23 255 277 255 277 0.95
2 16 0.15 12 6.9 1.1 2 23 284 306 283 306 0.95
3 16 0.0022 0.18 12.6 0.3 2 21 313 332 312 333 0.92
4 16 1.2e-05 0.00097 19.8 0.8 1 23 340 362 340 362 0.97
5 16 5.1e-06 0.00041 20.9 2.0 1 23 368 390 368 390 0.95
6 16 0.0035 0.29 12.0 0.7 2 23 402 423 401 423 0.97
7 16 0.00061 0.05 14.4 4.1 1 23 439 461 439 461 0.97
8 16 0.052 4.2 8.3 0.2 1 23 467 489 467 489 0.94
9 16 3.4 2.8e+02 2.6 3.2 1 23 499 522 499 523 0.93
10 16 0.1 8.3 7.4 0.0 1 21 536 556 536 557 0.92
11 16 0.0058 0.48 11.3 0.1 1 23 562 584 562 584 0.98
12 16 2.6e-06 0.00021 21.8 3.1 1 23 590 612 590 612 0.98
13 16 0.00023 0.019 15.7 0.6 1 23 618 641 618 641 0.97
14 16 0.063 5.2 8.0 0.7 1 23 647 669 647 669 0.89
15 16 4.2e-07 3.4e-05 24.4 2.2 1 23 675 697 675 697 0.99
16 16 8e-06 0.00065 20.3 4.9 1 23 703 726 703 726 0.96

Sequence Information

Coding Sequence
ATGCTGAAAGCGGAGTCCATAAGCACGATAAGTGACAGAGACGAAAACTTGGACGACGACATAGATGATCTCGATGGATCCATAATATGGTCGCAGGACGATCCTCTGTCttgcaatgaaattttagatCCCGAAACGAATATTGGTCCTGGAGGAGATGCACTAGGAAGTCCAATCACATTGTGCCGATTATGCGCCGGTCAAACTGTAAACccaatatacatttattcgGAAATCGGAGAATCATTGAAGCTTGCTCAAAAGATAAACACCTGCTTGAGCATTAAGGTGAGAATGACTGACCCTTTACCGAAGCAACTTTGCGTCACTTGTGTGGAGAAGATTAACTGGTGCAACGAATTCGACAACGAATGCATAAAAGCCGAAGAAACCTTAACGACGATGCTTCGCGAAAAGAGATGTTTTGAAGTATCGGAAGTGATAAGCAAGGATCAAAATTGTCATGATAAGTCGTGTCCTTTGTGTCTCGAAGGTCACATGACGACGACCCAGTTGAACACAAACGATCCGACATTCGAAGAATTATACGATAGCGACATTGTACTGGACAGCAGTGACGAGGAGAAGATGTTTAACGAATTGAAAATGGATAAGGAAGTCGGGAGCAATGCGATAATGCTGCAATGCCTTGGAAGCAGTCAGCAGTACCTGAAGTGCGGTGCCTGTATGAATCTCTATCACACCAAAGAGACCTTGGACAATCACAAGTGTAAGCCAAACGTTCAGAATACGTCTAAGCCGTATAAGTGCCTCATGTGTAATGCCACCTTTACTTTCGAAGAGCGATTGAATTTTCACATGCAGTTTCACGAGGGCGCCAAAGCCCTGTACTGCGAAGTCTGCAAAATTACCTTTGGCAAAGAGTTGAAGTTGTTTTATCATTACAAAAGGTATCACTGCGAGGCCATGACTGTATCCTGTCTGCAGTGtggaaaactttttgaaaatcaggAACAACTGAGGATCCACGTGTGCGTCGATGGGAAAACGAGGCCTCACGTTTGCGAGGTCTGCAACAAGGGTTTCTCCGACGGCTACACCTTGAAGCGACATATAGTAACTCATCTGCCTGAAAAGCCATACAAGTGTTCTCAGTGCTCCAAGAGTTTCACCCAAAAATCAAGACTCAATAAGCATGTTGCCGGTCACGGGATTGTTATCGAGAACACTCAAACCGCATGGAAGTGCGTTCAGTGTGGTGAGACCTTTAACAGCTGTGACGACGCAGACAGTCACTACAGGATTCACGAGGACAAAATCACCTTGATAGAAGAATTATCCACGTCGAAGATGTACCACTGCGAGTTCTGCAATAGCCACTTTGTCGATCCTGACAATTTGAAGACACATCAGAACCAGCACGTTGTCGAGAGACCCTACAGTTGTAATCTTTGTAATACAGTTTACAAATCCTTCGCCGAGGCGGTACTACACTGGAAGGAACATCCCAGAACGTTCAAGGTGGTCACGGTATTTCTCTGCGATCTCTGTAGCAAGGACATGAAGGAGTTGTCCCTACTGTACAAGCACAAACAGAAGAGACATCATTACGTGCCGAGAAAATCCGATTCCGGCAATATGATCTTTATCTGCGAACTTTGCGGCAGCACGTTTGAAAAGAGCGAGGAGATTCAGGAGCACGGTAGAGATCAGTGCTCAAAGTTTCCTTGCGACATATGCGGCAGTTTGTTACCCACTGCGAACTCCCTGAACGCCCATAAAAGAAGACACAGTGGTCTGCGTCCTTACGTTTGTAATATTTGTGGAAAAAGTTACACTCAGTCTAGTCATATGTGGACTCATAAGAGGTTTCACATGGGCGTAAAACCGTACGCCTGTCAGTACTGCGATCAGAGATTCACGATTAAGCCTGACCTGGCTGATCACACTAGAAAGAAGCACACCAGAGAAAGACCCTTTAAATGCGATGTCTGTAACAAAGCATTTCTCACAGGTTCGGTCTTTTATCAGCACCGACTGATTCATCGAGGAGATAGACGATACAAGTGTCACTATTGCGAAAAAGCATTCACCAGGACTGAAGCTCTGAACAATCACATTAAGATACACACTGGCGAGAAACCGCACGCTTGTGACGTTTGCGGAAGATGCTTTAGGCAGAAAGGCGACATGAGGAAGCACAGACGTACCCAACATGCTGCCAAGGAAGAACTTTCTTGA
Protein Sequence
MLKAESISTISDRDENLDDDIDDLDGSIIWSQDDPLSCNEILDPETNIGPGGDALGSPITLCRLCAGQTVNPIYIYSEIGESLKLAQKINTCLSIKVRMTDPLPKQLCVTCVEKINWCNEFDNECIKAEETLTTMLREKRCFEVSEVISKDQNCHDKSCPLCLEGHMTTTQLNTNDPTFEELYDSDIVLDSSDEEKMFNELKMDKEVGSNAIMLQCLGSSQQYLKCGACMNLYHTKETLDNHKCKPNVQNTSKPYKCLMCNATFTFEERLNFHMQFHEGAKALYCEVCKITFGKELKLFYHYKRYHCEAMTVSCLQCGKLFENQEQLRIHVCVDGKTRPHVCEVCNKGFSDGYTLKRHIVTHLPEKPYKCSQCSKSFTQKSRLNKHVAGHGIVIENTQTAWKCVQCGETFNSCDDADSHYRIHEDKITLIEELSTSKMYHCEFCNSHFVDPDNLKTHQNQHVVERPYSCNLCNTVYKSFAEAVLHWKEHPRTFKVVTVFLCDLCSKDMKELSLLYKHKQKRHHYVPRKSDSGNMIFICELCGSTFEKSEEIQEHGRDQCSKFPCDICGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACQYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHAAKEELS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01255863;
90% Identity
iTF_01131009;
80% Identity
iTF_00295448;