Ogra028257.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Orthosia gracilis
Gene Symbol
Baz2b
Assembly
GCA_947562075.1
Location
OX387276.1:5724180-5810557[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.8e-12 8.1e-09 35.8 0.0 3 75 636 711 634 713 0.89

Sequence Information

Coding Sequence
ATGGACAAGGAAGGGGGGGATGGCGGCGACGCGGCGGGCAAGCAGCCCCCCGATGGTCTGCTCGATGCCGCTAACCTCTTTGGAGCATACTGGGGCCGCGACGGCAGCAGCGGCGGTGGGGCGGCAGCAGCTCAGGCCCAAGCTCAAGCCCAGGCCGCGCTCTTCGGCTTTGGTGGCCGATACCCGCCACCCACCACGCTGGGTGTGGCGGCCAACCAGGCGGCCTCCCTCGGCCTGCATCCGGCAACCAGTGCAGCCTGGTGGTCGATGGCATCCCACCTAGCAGCTCAAGACTACCTAGCACGCCTGCAGGCCTCAGGGTTAAACTTCCCACCCCTGGCGGACCCCTACGCCGCGCTGTCAGCTCTGTCAGCTGGCCAGGGGTTGAAGCAGCCGCAGAAACCTGGGAAGTTGTCTAGTCGGAATGAGAGGTCAGGCAGAAGCAGTACATCATCGAGTGCGTCCACAAAAGACAAGAGTCCATCAACGAGCAGCACCAACTCGCAGAACATGAGGTCTTCCTACGGTCTCCCGAAGACATCATCTCCGTCCGCGATGCACCACTCCGCTTCTCTGTCGAGCCTGGCCTCTCTCAACAGCCTGGTGTCTGCTCCGCATCAGAGCAAGCATAGTAGCAAGCCGACGGCACAACCGCAGCCTAGCAAAAAGCCTTCCTCATCATCATCTTCCAGCTCCAAAGGCAAGGAGCGTGAGCTAGCGTTACTCCGCGGTGACCTCATGCTGGCGCAGGCAGCAGCACACGGCGCGTACCACGCCGCCGTGGCCGCGGCCGCTAAGGGCAAGAACATGTCACCGCTGTATCCATTCGGCATGCCAGGCTCTGATAAGGATGGCCGGCACGGCGGCATCGACTCCCTTACAGGCCTACCGCATACCATACTCAGTGCTGCTTTAGAAGGCGGCGATCCTTCATCAGTGCTGGGTGGTGTGAGATTGCCCCCCGACACAGAGATTATCAAGTATACCTCTTCGTTAGCTGGCGGGCCCAAGGCGGGTGCAAGCACGACGACCCGCGGACGAAAGAAGACGATCTCCTTAGACCCTCCGCACGTCAGTGTGCACCCCGCCGCCGCCGACCGGAACGCGCCGCTACCCAGCAAACGGCCTAAACTTGACGAGTACGGTAACTCCCGGTCGTCGGTCGAAGTGATCCGGCTGCCCAACAAACCGGACCGGCCCGGACACAACTCCATGTCCGGAACCCCGCCACCCAATCTGTCTGATTATGCAGGCATATCCCGAGAGCTGCTACAAACGATAGCTAGTCAGAGCGGCGTGAGCCTGGCCGCCTTGGAGCGACAGCTCGCGGGCTCCACAGATGCAGGTCTCAACCTCAGCACTAAGATGGGCGAGGATTCTCCCTTAGACCTGGGCGTCAAGTCTTCTGCAATGGACGACGATGCGCCTCTGAACCTGTCTCTCAAACCTACTCCTGCGAGTTCGCAAGCCTCAGACGCTCTCTCGCGACTAACGTCTCTGAGTAGTTCGCTCAACGCGTCTTCCAGCCATGACAGGATATCGCGTCGCAAGCCAGGCGCGAAGCCCCGGCGCGTGGCCCCAGAGATGAACCCCGTACCCGACGCTCCACGACCCAAGTCCAGCGGCAGTGAGGACAGTGAATCAGTAGCGGGGTGGGCAGGCCGCGAGGGCAGGCCGCGCAACCTGGGCCGGGGAGTCAGCAAGCCTAAGAAGAATACTGTGGCCTCTTTATTGGCACAGAGTCGGGCCTTGGGCCTGAGGCCGGCGCTGGCGCATCAGTTGCTGGCGGAGACTGACTTGGAAAAACTAAAAGCGCTGCTCGGCGAGACAGCGAGCACGGACTCGGAGTGTCCGTCGGATAGCTGTCCGTCCGATTCAGACGCGTCCGACACCAGTCGGAGACCGACCGACGCGCAACTCAGACTGCCCTTAGCGCTGGGTTGGAAACGCGTAACTGTGATCAAAGGACTATCCCGGAACTGCAACATCAAAGGTGACGTGACGTATTCACCGCCCGACCCGCATGCGGGCATCACTATGCGGTCGTTACATGAAATACAGAACTTCCTAGACTCGAACCCCTGTCCGCCTCTATCGACGGACAACTTTAGTTTCTCTGCGCGCACTGTGTTAGGAGAATACATACAACCTGCCAGTGATGTGGGAGAACCGCTGGTCTATAACGAAAACGAGATAAATAAGAGACTGGAAGAAGCTCGTATCCTGGCATCAGCAGGTGGGCGGCCCACCCCGCCGCCACTAGACCGGCGCATGGAGCTGGCGCGCCTGCAGCAGGCCGCCAGGGACGCGCGCCGCGACGCCACGCACAGGAGCCGGGACCAGGCCCGTCTCGAAAGATCAGAGAAAGCGGAACTAGCTAAACGCGAGAAGGAAGCGAGAAGTCAACAGCTGCTAGAGCATATCAACAAGAATCGAACGCAGTTGACGATCGAGCCGCTCCCTACGATCCCAAAAACCGGTATCGACGAGTGGAAAACACCCGAGATAGTGATGGGACCAGCCACTAAGACGAGTAAAGATCGCATTATGCCCCCAATAAGCCTCTCCCTAATACCAGTCACCGGTCCCAAAGACTCACAGAACTCCCCCATAAAAACCATAAAATTCGACCAATCGGGATGGAAGGAAGAAATAGAAGAATACAACGCGCTTGATAAAATGAAACACTTCGCTGAAAAAGCGGCCTTCGATCTCCCGAAACGAAAAGACAATAAACAATACGATTTCTCGTTAGTAAAACAAGCGGAAAAGCGCTTGAAAGCGCCCGAAAAAGAGAATAACTTAGAAAAACTTATAGAATCTTACTCAAGGATAACAGAATTCATAAACGGCTGTGATTGGTCGAAACTACAAGGGGATAAGAAAACTGAAGACCCGAAGTCAATAGAACAGAAATATCTGGACGCAAAAAACGAATTTATGTCCCAGAATTTGATGTTGATGCCTAAAGACAGTCCCAAATCTGTTTTAAAGGAAGTTATAGACTTGAGCGAAGACGACGATATTTTGACTGATATTATGTCTAAGAAAATAAGTAAAGGGACGTTTAACGTGGGCAAAGACGGGGCCTTATCGATATCTGTCCACCCCCTAAGCAAGGATCCGTTGGCTAAGAGGAGAAAGCACGAGGAGATTGAGAAGCAGAAGATTGAAGAACAGGCTAAAAGGCAGCAGGAGAGAGAGTTAAAGCGGCAACAGGCCATACTACTGAAAGAACAGGAAAGAGAACGGCGACGCCAGCACACGACCTTCATCCGTCAGCTGGACTCCCGCAGGCGGTGGGAGGAGAGAGAGAGAAGGAAGCACCAGAACTTGCTAGATAGATTGCTGGTGAAGGAGAAGAAGTTGCAGCAGAGAAGGAAGGAGATGGAACTGCTTTCTGAGCTAAGACGACCACAAGAAGACTCGTCGCTGTCAGACCAGAAGCCACTGCCCACCTTGAACAGGATCCCCGGACTGAAGCTGCCAGGCCAAGCCATGGCCGACATTCTACAAGTATACGAGTTTATACATAACTTCGGACAAACACTTGGTTTTGACATGGACGCAATCCCAACGCTGAACACGTTCCAAATGGCGCTGCTACCTGACTGTAGCGTAGAGGCTGAAGAAGAACTGCTACAAGTACTCACACAGCTACTTATTACTGCCATTGAGGACCCAGGTATCCCACACCCGGGGCGTCACACCACACTGCTGGGCCACGCCATCAGGATGGGCGACATCACGCCGCAGAACATCAGCGAGGTGCTCCGAATATACCTGTATGCCAATGCTACGGGAGAAGTCAAGGCTCTAACTGGATTAACAGCGGAGAGAGAACGCGAACGTCGCGTCGCCGACCACCATCAGACTGAGGCTGAAATGCAACACACCTGTGCCAACTCCAAGAACAACGTTTATTATGAAAGTCTACATAATAACGCTACTTATAAACTTTCAGAGGCCCTCCGCGACAAATCATTCCTCGCTCTAAGCGCGACCTTTAAAGCTCGCATCCTGGCCTTCATATGTGACGAGCTGCTACAGAACAAGGCAGTGCTAAGACAAGTGGACGCCAGCCTCGAACACCTGAATCAGCTCAAGAAGGAGAGATATCTGATGGACATGAAGATTAGGAAGGTCAGAGTACTCCATCAACGCAAAGTCCGCGCGGAACAAACAGAAAAGCAGCAAGCTTTAGCGCTGGAACGTATGCAGCGTCTAGTAGAAGAAAGCGCTGCCAACCTGAGAACGTCACCACATTTGAATGACGACGAAAATCAACAAACACCAGAAAAGCCAGAAACGCCTAAAAAAGACAAAGAATCTTCTCCACACCCCGAAAGTGAAACAGACAAGCAATCCGAGCCCTCTCCATACAAGGAGAGCCCACCAACCGAAGAGAGCGACAAGGAACTATCGCCTTTAAAGGACCTCTCCAACAGTATGAAGAACAAAGAGATGTTGAATAACAATAAGGACGAGTGCTCCCCGGCTGATAACTCGAAGATTGATAAGGACAGTGTTATTGGAGACTGCGATGCCAATTTGAGTGATTTGGAGAGTGAAGGGACGCAGCCGGAAGAGGATGAAGACAAAAACTTATCGTCCGAGGAACTGGCTCGCAAGCTGGAGAAGCTTCTGAAGCAGTCTGAACAACAGCTGCTGCAGCTAACTGCTGGATCCCATGCTTTGAGAGCTACGTGTTATGGACAGGATAGATATTGGCGCCGTTACTGGTCTCTCGGCAAATGCGGCGGCATCTTCGTAGAAGGCATGGAGTCTGCGCAGCCAGAGATCATGACGTATCACCAACAGCTGGAGAACAATGCGCTCAGCGGCAACAGCCCGCCAGATACCAGCAAGAAGAAGAAGAAAGTTCCCCGAGAGAAGAAAGAACCCTCCCCTCTGGAACCTGAGAAACCAAACCCAGAAACAGAGGCCCAGAAGAAAGAAGAGGCTCTCAAGAGTGAGATGGAGCTCAAGAGCATCAAGTCCGAGTTGAACCTGAGTGATCACACGCAAATCATCAAGTACGAGCCCAATGTCAAGCATGGCGCTTGTAAGGTTGAAGGCTCCTCAATAAAAATGGAAGAAAAATACATCCAACAGAAGAACAACGAAGAACAAGACATGCTTGACATAGAAGACTCCATACCCACCGCCTTCCTAGTACAAAAACCCACCCACAAGCCAATGTTCGCGGCCCAAGCAGAACCCATGGACAAGCCCCAAGAAATCGTCAAGGTTGAAAACGTAGTGAAGAATGAAGCCGAACATGAAGACATAGAGGAGACTAAAGATACTTTAGTTAACAACTTGGAAGAGTTACGCAAAATGGCCGAAGCGGTCTCCATACAATTAGATGCTGCTAAGAAGGAACAAGAAATTAAAGAGGAAAAAGAAAAAGTCAAACAAGAACCGTTAGATGCCGCCGATGCGCATCTACAACTCTATTCAAAGATATTAGAAGGAAAATGGTTCTCAATCCTCAGACACGAAAGTTCATTTTTGAACAACATCAACGAAATCGAAAAGCAAGACCTACCTGAGTTCTGTGACAACGAACATACTTGTTCCGAAGTCATTCTGTGTCAAGGACATAAGTGGGATGTTTCGAACAATCTTCACTTGTTGAATGACCCGAGTCTGTTTACATTAAACAGTATGGTGACTAGTGTTCAGGTACCGTCGAATAATGTGTATGCTGATTCTGCTTTGACCATGTCTGGGTTGGATCAGGAAATTATTGATAATAGTTTTAATAAGGATGGGAGTGTGATGGAAATGGAAACAGAGGAAGATAGTAAGGAACAGGACAACGACCTAGAAAAAGAATTACAAGCTGACGCCCTAAAACACGACCTCCTCACTCAGAAGGCCAAAGCCAACAGCCTAACAAGTCTAGGGCTTCTGAACTTCAACGCTCTCTCCACATACGTGACGTGCGACAGTCCGCCGCCCATACAGATGTGCGCAGAGGAGATGGACCAGCTGGAGCACTGCAAGCTCAATGGACTGCCCAAGAAGGTCGAAGGGAACTTCGTACCCAGGGAGTTGAGACACGGCTGGTGGCGAATCACAGAAACAGATCAACTACGTGACTTGATGGACTGTCTACACCCGCGCGGCGTCAGAGAGAGAGAACTACATAACTCCCTCACACACCATCTACCGACCGTTAACAATAAGCTTTACATAGAAAAGGGCGATATTCTAGGCACAGAGCTATGTGTGTCTCATCTAGACCGAGTCATCGCACAGAATGGGGGCTTCCCTTCACCGGACACATCGCACTCCGCGATGACTCAGAGAAGACTTGATATGCAGTTGCTGAACATGGTGGAACAACTAGAAGAACGTGTAGCAGCAGCCTCCATGCAAGTCAAAGGTTGGCGACCAGCTCGAGGAGCATCCGACAGCTCCCCTTCAGAGCCCGTGGCCCGAGCGCGGCACAAGTTGCAGGTGCTAGAGGCGCACATCGAGCGGAGGTACCTCAAGCCGCCGCTCGTACAAAGGTACGCTAGTACATCCGAGGCGACACTGGGTGCAGTGCTGCAGGCCGAGCACGGCAACGCATCCGCGCCTTCGCCGCAGCACACCGCCTCCCCTAGCGAGGGGAAAACTGACAACAAAGGCATAGCCCGAGGCCTAGCAACCTGGCGCGAAGCAGTGGCTCGCTGCAACACTTCCGCTCAACTAGCGATGTCACTACAAGCGTTAGAGGCAGCGGTCGCGTGGGATAAGAGCATCATGAAGGCGAACTGTCAGTTTTGCTTGTGCGGCGACAATGAGGGACATCTGCTACTGTGTGACGGCTGTGATAAGGGCTATCACACGTACTGCTTCAAGCCACAAATGGATAAGATTCCTGATGGAGACTGGTACTGTTGGGAATGCATAAACAAAGCCAGAGGCGAGCGTGTCTGTATCGTATGCGGTGGTGCCAACGCGAACACTCGCACCATACCCTGCGCGCTTTGTTCCCGAGCTTACCATCAGGATTGCCACTATCCACCACTGCAAAAGAACCCCCGCGGAAAGTGGTACTGCTCGCAGTGCATCTCACGCGCGCCGCCCAAGAAGCCGCGCAACACCAAGAAGAGGGACAACAAGCATCGCGATCTCAACGCTAGTCTAGATATCGACCAGAACATGGTGCCTAGTCCAGCAGCATCGCACGCCTCAACATCAACAACAGCGGAAGAATGTTCCGGATCAGCGCTCCACACGCCGGAAAAACATGACGACAAACTAGATGATACGCTCCCGGACAGCGAGAACGGATTGAATCATCACACAGGTGAGCTAAGTGCAGAAGAGGGTCCTCCGGAGAAGCGTCGCGCGCTGCAGTACGTGGGCGGTAATGGAGCCCTACAGCATGAAGAGAGTCGTGACTCAATTGTAGACGTAGAAGACACACGCGACACAGAGAGCGCGCCGCTGTTGTCTCGCGCTAAGAAAGAGAAGAACCAAGCCAAGAAACTTGTCAAAGAAATACAGTTTTGCAAGAATCTCCTAAACGAGATGGAGTGCCACGAGCACGCGTGGCCGTTCTTACTGCCGGTGAACACCAAGCAATTCCCTCAGTACAAGAAGGTCATCAAGTGCCCCATGGACCTCTCCACTATCAAAAGGAAGCTCACGGATAACATCTACAAATGCAAAGAAGAGTTCGCTTCTGACGTTCGCCTGATCTTTGGCAACTGCGAAGTGTTCAACGAGGACGACAGCCCCGTCGGTCGCGCGGGACACAACATGAGGCAGTTCTTTGATGAGCGCTGGGCGCAGATATGA
Protein Sequence
MDKEGGDGGDAAGKQPPDGLLDAANLFGAYWGRDGSSGGGAAAAQAQAQAQAALFGFGGRYPPPTTLGVAANQAASLGLHPATSAAWWSMASHLAAQDYLARLQASGLNFPPLADPYAALSALSAGQGLKQPQKPGKLSSRNERSGRSSTSSSASTKDKSPSTSSTNSQNMRSSYGLPKTSSPSAMHHSASLSSLASLNSLVSAPHQSKHSSKPTAQPQPSKKPSSSSSSSSKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGSDKDGRHGGIDSLTGLPHTILSAALEGGDPSSVLGGVRLPPDTEIIKYTSSLAGGPKAGASTTTRGRKKTISLDPPHVSVHPAAADRNAPLPSKRPKLDEYGNSRSSVEVIRLPNKPDRPGHNSMSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSTDAGLNLSTKMGEDSPLDLGVKSSAMDDDAPLNLSLKPTPASSQASDALSRLTSLSSSLNASSSHDRISRRKPGAKPRRVAPEMNPVPDAPRPKSSGSEDSESVAGWAGREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLAETDLEKLKALLGETASTDSECPSDSCPSDSDASDTSRRPTDAQLRLPLALGWKRVTVIKGLSRNCNIKGDVTYSPPDPHAGITMRSLHEIQNFLDSNPCPPLSTDNFSFSARTVLGEYIQPASDVGEPLVYNENEINKRLEEARILASAGGRPTPPPLDRRMELARLQQAARDARRDATHRSRDQARLERSEKAELAKREKEARSQQLLEHINKNRTQLTIEPLPTIPKTGIDEWKTPEIVMGPATKTSKDRIMPPISLSLIPVTGPKDSQNSPIKTIKFDQSGWKEEIEEYNALDKMKHFAEKAAFDLPKRKDNKQYDFSLVKQAEKRLKAPEKENNLEKLIESYSRITEFINGCDWSKLQGDKKTEDPKSIEQKYLDAKNEFMSQNLMLMPKDSPKSVLKEVIDLSEDDDILTDIMSKKISKGTFNVGKDGALSISVHPLSKDPLAKRRKHEEIEKQKIEEQAKRQQERELKRQQAILLKEQERERRRQHTTFIRQLDSRRRWEERERRKHQNLLDRLLVKEKKLQQRRKEMELLSELRRPQEDSSLSDQKPLPTLNRIPGLKLPGQAMADILQVYEFIHNFGQTLGFDMDAIPTLNTFQMALLPDCSVEAEEELLQVLTQLLITAIEDPGIPHPGRHTTLLGHAIRMGDITPQNISEVLRIYLYANATGEVKALTGLTAERERERRVADHHQTEAEMQHTCANSKNNVYYESLHNNATYKLSEALRDKSFLALSATFKARILAFICDELLQNKAVLRQVDASLEHLNQLKKERYLMDMKIRKVRVLHQRKVRAEQTEKQQALALERMQRLVEESAANLRTSPHLNDDENQQTPEKPETPKKDKESSPHPESETDKQSEPSPYKESPPTEESDKELSPLKDLSNSMKNKEMLNNNKDECSPADNSKIDKDSVIGDCDANLSDLESEGTQPEEDEDKNLSSEELARKLEKLLKQSEQQLLQLTAGSHALRATCYGQDRYWRRYWSLGKCGGIFVEGMESAQPEIMTYHQQLENNALSGNSPPDTSKKKKKVPREKKEPSPLEPEKPNPETEAQKKEEALKSEMELKSIKSELNLSDHTQIIKYEPNVKHGACKVEGSSIKMEEKYIQQKNNEEQDMLDIEDSIPTAFLVQKPTHKPMFAAQAEPMDKPQEIVKVENVVKNEAEHEDIEETKDTLVNNLEELRKMAEAVSIQLDAAKKEQEIKEEKEKVKQEPLDAADAHLQLYSKILEGKWFSILRHESSFLNNINEIEKQDLPEFCDNEHTCSEVILCQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPSNNVYADSALTMSGLDQEIIDNSFNKDGSVMEMETEEDSKEQDNDLEKELQADALKHDLLTQKAKANSLTSLGLLNFNALSTYVTCDSPPPIQMCAEEMDQLEHCKLNGLPKKVEGNFVPRELRHGWWRITETDQLRDLMDCLHPRGVRERELHNSLTHHLPTVNNKLYIEKGDILGTELCVSHLDRVIAQNGGFPSPDTSHSAMTQRRLDMQLLNMVEQLEERVAAASMQVKGWRPARGASDSSPSEPVARARHKLQVLEAHIERRYLKPPLVQRYASTSEATLGAVLQAEHGNASAPSPQHTASPSEGKTDNKGIARGLATWREAVARCNTSAQLAMSLQALEAAVAWDKSIMKANCQFCLCGDNEGHLLLCDGCDKGYHTYCFKPQMDKIPDGDWYCWECINKARGERVCIVCGGANANTRTIPCALCSRAYHQDCHYPPLQKNPRGKWYCSQCISRAPPKKPRNTKKRDNKHRDLNASLDIDQNMVPSPAASHASTSTTAEECSGSALHTPEKHDDKLDDTLPDSENGLNHHTGELSAEEGPPEKRRALQYVGGNGALQHEESRDSIVDVEDTRDTESAPLLSRAKKEKNQAKKLVKEIQFCKNLLNEMECHEHAWPFLLPVNTKQFPQYKKVIKCPMDLSTIKRKLTDNIYKCKEEFASDVRLIFGNCEVFNEDDSPVGRAGHNMRQFFDERWAQI