Mimp056034.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mythimna impura
Gene Symbol
Baz2b
Assembly
GCA_905147345.1
Location
LR990369.1:11799513-11895281[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.3e-12 4.9e-08 34.3 0.0 3 75 628 703 626 705 0.89

Sequence Information

Coding Sequence
ATGGACAAGGAAGGGGGGGATGGCGGCGATGCGGGCAAGCAGCCCCCCGATGGCCTGCTCGATGCCGCTAACCTGTTTGGTGCATACTGGGGCCGCGATGGCAGCAGCGGCGGCAGTGCGGCTGCGGCACAAGCGCAAGCGCAGGCACAAGCCGCCCTCTTCGGTTTCGGCTCCCGCTACCCGCCCCCCACGACCCTGGGGGTGGCGGCCAACCAGGCGGCCTCGCTCGGCCTGCATCCAGCTGCCAGTGCAGCCTGGTGGTCGATGGCATCCCACCTAGCAGCTCAAGACTACCTAGCGCGGCTGCAGGCCTCAGGGTTGAACTTCCCTCCCCTGGCTGACCCCTACGCGGCACTGTCAGCGCTGTCAGGAGGCCAGGGGCTGAAGCAGCCGCAGAAACCTGGGAAGCTGTCTAGTCGGAATGAGAGGTCAGGCAGAAGCAGTACATCATCGAGCGCGTCGACAAAAGACAAGAGCCCGTCGACGAGTAGCGCCAACTCTCAGAACATGAGATCGTCGTACGGTCTCCCGAAGACGTCGTCTCCGTCCGCGATGCAGCACTCCGCCTCCCTTTCGAGCTTGGCTTCTCTCAACAGCCTGGTGTCTGCTCCGCATCAGAGCAAGCACAGCAGCAAGCCGTCGCAGGCGCCGCAGCCTACCAAAAAGCCGTCGTCATCGTCGTCGTCGAGCTCCAAAGGCAAGGAGCGCGAGCTGGCGTTACTCCGCGGCGACCTCATGCTGGCGCAGGCGGCCGCGCACGGCGCCTACCACGCCGCCGTGGCTGCCGCTGCCAAGGGCAAGAACATGTCACCGCTGTACCCGTTCGGCATGCCGGGCTCGGACAAGGACGGTCGGCACGGCGGGATCGATTCCCTCACTGGCTTGCCGCACACCATACTTAGTGATCCTTCGTCAGTGCTGGGCGGGGTGCGCTTGCCTCCCGACACAGAGATTATCAAGTACACGTCCTCGTTGGCCGGGCCCAAGGCGGGTAGTACGACGACCCGCGGACGAAAGAAGACGATCTCCTTAGACCCACCGCACGTGAGCGTGCACCCCGCCGACCGGAATGCGCCGCTGCCGAGTAAACGGCCTAAACTTGACGAGTACGGCAACTCCCGGTCGTCAGTGGAAGTGATCCGGTTGCCCAACAAACCGGACAGGCCCGGACATAATTCCATGTCTGGTACCCCACCACCCAATCTGTCCGATTATGCAGGCATATCCCGAGAACTGCTACAAACGATAGCTAGTCAGAGCGGCGTGAGCCTGGCGGCACTGGAGCGGCAGCTCGCCGGCTCCACAGGTGATTATTATGCAGGTCTGAACCTAAGCACAAAGATGGGCGAAGACTCTCCATTAGACCTGGGCGTCAAGTCCTCTGCGATGGACGACGATGCACCGCTGAACCTTTCACTTAAACCTACTCCTGCGAGTTCGCAAGCGTCGGACGCTCTCTCGCGACTGACGTCTCTGAGCAGTTCGCTTAACGCGTCCTCCAGTCATGACAGgatatCCCGCCGCAAGCCGGGCGCGAAGCCGCGTCGCGTGGCCCCCGAGATGAATCCCGTACCCGACGCGCCGCGGCCCAAGTCCAGCGGCAGCGAGGACAGTGAATCAGTAGCTGGGTGGGCAGGGCGCGAGGGACGGCCGCGCAACCTCGGCAGAGGAGTCAGCAAGCCCAAGAAGAACACGGTGGCCTCGCTACTGGCGCAGAGTCGCGCCTTGGGGCTGAGGCCGGCGTTAGCGCATCAGTTACTGGCTGAAACTGACCTGgaaAAACTAAAAGCGCTACTAGGCGAGACGGCGAGTACAGACTCGGAATGCCCATCGGACAGCTGTCCGTCCGATTCGGACGCGTCCGACACCAGTCGGAGACCGACCGATGCGCAGCTCAGACTACCCCTAGcactagGTTGGAAACGCGTGACTGTGATCAAAGGATTGTCCCGAAACTGCAGTATCAAAGGTGACGTGACGTATTCACCGCCCGACCCGCATGCGGGCGTCACCATGCGGTCACTACATGACATACAAAATTTCCTAGACACGAACCCCTGTCCGCCGCTGTCGACGGACAACTTCAGCTTCTCTGCGCGCACCGTGCTCGGAGAGTACATCCAGCCGGCCAGCGATGTAGGAGAGCCGCTGGTCTATAACGAGAACGAGATTAATAAGAGACTGGAAGAAGCCCGTCTGCTGGCTTCAGCAGGTGGGAGGCCCACCCCGCCGCCGCTGGACCGGCGCATGGAGCTGGCGCGCCTGCAGCAGGCCGCGCGGGACGCACGACGAGACGCCTCGCACCGCAGCCGGGACCAGGCCCGTCTCGAAAGATCAGAGAAAGCGGAACTAGCCAAACGCGAGAAAGAAGCCCGAAGTCAACAGCTGCTAGAGCATATCAACAAGAATCGAACGCAGTTGACGATCGAGCCCCTCCCTAGCGTCCCGAAAACCGGTATCGACGAATGGAAAACACCGGAAATAGTGATGGGACCCGCTACTAAGACGAATAAGGAACGCATTATGCCTCCAATCAGTCTCTCCCTAATACCGGTGTCCGGCCCCAAAGACTCTCAAAACTCCCCTATAAAAACGATAAAATTCGACCAATCAGGATGGAAGGAAGACGTTGAAGAGTACAATGCGCTTGATAAAATGAAAGACTTCGCTGAAAAAGCGGCTTTCGATCTTCCAAAACGTAAAGACAACAAACAATACGactttacattaataaaatcagCTGAAAAGCGCTTGAAAGCGcccgaaaaagaaaacaatttagaAAAATTAATTGAATCGTACTCAAGAATAACAGAATTCATTAACGGCTGTGATTGGTCTAAACTACAAGGAGATAAGAAGACTGAAGACCCAAAGGCTATAGAACAGAAATATTTGGACGCGAAAAACGAATTCATGTCACAGAACTTAATGTTAATGCCTAAAGACAGTCCGAAATCTGTTCTAAAGGAAGTCATAGACTTAAGTGAGGATGATGATATTTTGACAGATATCATGTCAAAGAAAATCAGTAAGGGGACGTTTAATGTGGGCAAAGATGGCGCCCTATCCATCTCAGTACATCCGCTAGGCAAGGAATCGTCGGCTAAGAGGAGAAAACACGAGGAGATTGAGAAGCAGAAGATTGAAGAACAAGCTAAAAGGCAGCAgGAGAGAGAACTAAAGCGGCAACAGGCCATACTTCTCAAAGAacagCAAAAATATATAACCGAGGAAAGAGAACGCCGACGGCAGCACACGACCTTCATCCGGCAGCTGGATTCCCGCAGACGATGGGAGGAGAGAGAGAGACGGAAGCATCAGAACTTGCTCGACAGACTGCTGGTCAAGGAGAAGAAGTTGCAGCAGAGGCGGAAGGAGATGGAGTTGCTTTCTGAACTGAGACGGCCACAAGAAGACTCGTCGCTCTCCGACCAGAAGCCGCTGCCCACTCTGAACAGGATCCCCGGCCTCAAACTGCCGGGACAGGCCATGGCTGACATACTACAAGTATACGAGTTTATACATAACTTTGGACAAACGCTTGGTTTCGACATGGACGCTATCCCAACTTTGAACACGTTCCAAATGGCGCTCCTTCCTGACTGCAGCGTGGAGGCCGAGGAAGAACTACTACAAGTGCTCACACAACTACTTATTACTGCCATTGagGACCCAGGAATCCCACACCCAGGTCGTCACACAACCCTACTAGGCCACGCCATCAGGATGGGCGACATCACGCCGCAGAACCTGAGCGAAGTGCTCAGAATATACCTGTATGCCAACGCTACCGGAGAAGTCAAGGCTCTCACTGGATTGACAGCAGAACGAGAGCGCGAGCGCCGCGTGGCCGACCATCATCAGACGGAGGCTGAAATGCAACACACATGTGCCAACTCCAAGAACAACGTCTATTATGAGACCCTGCACAATAACGCTACATATAAACTATCAGAGGCTCTCCGTGACAAATCCTTCCTCGCTCTGAGTGCGACCTTTAAAGCGCGTATCCTCGCGTTCATCTGCGACGAGCTACTtcaaaacaaagcaattttaagaCAAGTGGACGCCAGCCTCGAACACCTGAACCAGTTGAAGAAGGAGAGATATCTTATGGATATGAAGATCAGGAAGGTCAGAGTACTCCATCAACGCAAAGTCCGCGCCGAACAAACGGAAAAACAGCAAGCTCTAGCGCTGGAGCGGATGCAGCGGCTCGTGGAAGAGAGTGCTGTCAACCTGAGGGCGTCGCCACAACTCAACGATGACGAAAACCAACAAACACCAGAAAAACCAGAAACTCCAAAAAAAGACAAGGAATCTTCACCACACCCCGAAAGTGAAACGGACAAACAATCAGAACCATCGCCTTATAAAGAGATCCAACCAGCCGAAGAGAGCGACAAGGAATTATCGCCCTTAAAGGATCTGTCCAACAGTATGAAGAACAAAGAGATGTTGAATAATAATAAGGACGAATGTTCTCCGGCTGATAACTCGAAGATTGATAAGGATAGTGTTATTGGGGACTGTGATGCTAATTTGAGTGATTTGGAGAGTGAGGGTACGCAGCCGGAAGAGGATGAAGACAAGAACTTATCTTCAGAGGAGCTAGCCCGCAAGCTGGAGAAGCTACTCAAGCAGTCAGAACAACAGCTTCTGCAGCTCACGGCTGGGTCTCATGCTTTAAGAGCTACGTGTTACGGACAGGACAGATACTGGCGCCGCTACTGGTCTCTCGGCAAATGCGGCGGTATCTTCGTGGAAGGCATGGAGTCTGCCCAGCCGGAGATCATGACGTACCACCAGCAGCTGGAGAATAATGCCCTTAGTGGCAATAACCCGCCGGACACCagcaagaagaagaagaaagCTCCACGAGAAAAGAAAGAGCCCACCCCTACTGAAGTAGAGAAGCCCAACCCTGAAACAGAAGCCCAGAAGAAGGAAGAAGCTCTCAAGAGCGAGATGGAACTCAAGAGCATCAAGTCAGAGTTGAACTTGAGTGATCACACGCAGATTATCAAGTACGAGCCCAATGTTAAACATGGCGCTTGTAAGGTTGAAGGCTCCTCAataaaaatggaagaaaaatacatCCAACAAAAGAACAATGAAGAACAAGACATGCTCGATATAGAAGACTCCATACCCACCGCCTTCTTAGTACAGAAACCCACTCACAAACCCATGTTCGCAGCCCAAGCGGAGCCCATGGACAAGCCGCAAGAGATCGTCAAGGTAGAAAACGTCGTCAAAAACGAGACAGAACATGAAGATATAGAAGAAACGAAAGATACTTTAGTCAATAACCTTGAAGAACTAAGAAAAATGGCCGAAGCGGTCTCCATACAACTTGACGCTGCGAAAAAGGAACAAGAAATCAAAGAAGAAAAGGAAAAGGTCAAGCAAGAACCTCTGGATGCTGCGTCGGCGCATCTACAACTCTACTCGAAGATATTAGACGGGAAATGGTTCTCTATCCTCAGGCACGAAAGCTCATTTTTGAACAACATCAACGCGATTGAGAAGCAAGATTTACCTGAGTTTTGTGATAATGAACATACTTGTTCAGAGGTGATTTTGTGCCAGGGTCACAAGTGGGATGTGTCGAACAATCTTCATTTACTAAATGATCCAAGTTTGTTCACGTTGAACAGTATGGTGACCAGTGTACAAGTGCCGTCAAATAACGTGTATGCAGATTCAGCGTTGACGATGTCTGGACTAGATCAAGAAGTAATTGATAATAGTTTTAATAAGGATGGCAGTGTTATGGAGATGGAGAGTGAGGATGATAGTAAGGAACAGGACAACGACTTAGAGAAAGAACTACAAGCCGACGCTTTAAAACACGACCTGCTCACCCAAAAGGCGAAAGCCAACAGCCTCACAAGTCTAGGGCTACTGAACTTCAACGCTTTGTCAACATACGTGACGTGCGACAGTCCGCCGCCCATACAGATGTCTGCTGAGGAAATGGACCAGCTGGAGTACTGCAAGGTTAACGGCCTGCCGAAGAAAGTTGAAGGGAATTTTGTACCCAGGGAGCTGAGACACGGCTGGTGGCGGATCACAGAGACGGATCAGCTCCGTGACTTAATGGACTGTCTTCATCCGCGCGGCGTTAGGGAGAGAGAACTACATAATTCTCTCACCCACCATCTGCCTACTGTCAATAATAAGcTCTACATAGAAAAAGGTGACATCTTAGGTACAGAGTTGTGTGTGTCTCATCTCGACCGCGTGATCGCTCAAAATGGTGGCTTTCCTTCACCCGACACGTCTCACTCGGTGCTGACGCAGAGAAGACTGGATATGCAACTATTAAATATGGTGGAACAGTTAGAAGAGCGTGTAGCAGCAGCGTCGATGCAGGTGAAGGGCTGGCGGCCGGGGCGCGGCGCGGAGGCGGCGGGGGAGGCGGTGTGCCGCGCGCGCCACAAGCTGCAGGCGCTGGAGGCGCACATCGAGCGGAGGTACCTCAAGCCGCCGCTCGTGCAAAGGTACGCTAGCACATCAGAGGCGACGCTAGGCGCAGTGCTGCAGGCTGAGCACGGCAACGCGTCCGCGCCCTCGCCGCAGCACAGCGACACTACTAGCGAGGGGAAagCTGACAACAAAGGTATTGCCCGCGGCCTAGCAACCTGGCGCGAAGCAGTAGCACGCTGCAACACCTCCGCTCAGCTGGCGATGTTACTCCAAGCCCTGGAAGCAGCAGTGGCTTGGGACAAGAGCATCATGAAGGCGAACTGTCAGTTTTGCTTGAGCGGCGACAATGAAGATCAACTGTTACTGTGTGACGGTTGTGATAAGGGCTATCACACGTACTGCTTCAAGCCACGGATGGATAAGATACCTGATGGGGATTGGTACTGCTGGGAGTGCGTGAACAAGGCGCGCGGGGAGCGCGTGTGCATCGTGTGCGGCGGCGCCAACGCGCACGCGCGCACCATCCCGTGCGCGCTGTGCTCGCGCGCCTACCATCAGGACTGCCACTATCCGCCGCTGCCTAAGAACCCTCGCGGCAAGTGGTACTGCTCGCAGTGCATCTCTCGCGCGCCTCCCAAGAAGCCGCGCAACACCAAGAAGCGCGACGCTAAGCATCGCGACCTCAACGCCAGTCTCGACATCGACCAAAACATGGTGCCCAGCCCTGCAGCCTCCCACGCCTCAACATCAACTACAGCAGAAGAATGTTCCGGCTCAGCCCTCCACACTCCAGAGAAACATGACGACAAGCTAGATGATACACTTCCTGACAGTGAGAACGGACTCAATCATCACACAGGTGAGCTCAGTGCAGAGGAAGGCCCTCCGGAAAAACGGCGCGCGCTGCAGTACGTGGGCGGTAATGGAGCCCTACAGCATGACGAGACTGATACACACATGGATGGTACGTAA
Protein Sequence
MDKEGGDGGDAGKQPPDGLLDAANLFGAYWGRDGSSGGSAAAAQAQAQAQAALFGFGSRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPLADPYAALSALSGGQGLKQPQKPGKLSSRNERSGRSSTSSSASTKDKSPSTSSANSQNMRSSYGLPKTSSPSAMQHSASLSSLASLNSLVSAPHQSKHSSKPSQAPQPTKKPSSSSSSSSKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGSDKDGRHGGIDSLTGLPHTILSDPSSVLGGVRLPPDTEIIKYTSSLAGPKAGSTTTRGRKKTISLDPPHVSVHPADRNAPLPSKRPKLDEYGNSRSSVEVIRLPNKPDRPGHNSMSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSTGDYYAGLNLSTKMGEDSPLDLGVKSSAMDDDAPLNLSLKPTPASSQASDALSRLTSLSSSLNASSSHDRISRRKPGAKPRRVAPEMNPVPDAPRPKSSGSEDSESVAGWAGREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLAETDLEKLKALLGETASTDSECPSDSCPSDSDASDTSRRPTDAQLRLPLALGWKRVTVIKGLSRNCSIKGDVTYSPPDPHAGVTMRSLHDIQNFLDTNPCPPLSTDNFSFSARTVLGEYIQPASDVGEPLVYNENEINKRLEEARLLASAGGRPTPPPLDRRMELARLQQAARDARRDASHRSRDQARLERSEKAELAKREKEARSQQLLEHINKNRTQLTIEPLPSVPKTGIDEWKTPEIVMGPATKTNKERIMPPISLSLIPVSGPKDSQNSPIKTIKFDQSGWKEDVEEYNALDKMKDFAEKAAFDLPKRKDNKQYDFTLIKSAEKRLKAPEKENNLEKLIESYSRITEFINGCDWSKLQGDKKTEDPKAIEQKYLDAKNEFMSQNLMLMPKDSPKSVLKEVIDLSEDDDILTDIMSKKISKGTFNVGKDGALSISVHPLGKESSAKRRKHEEIEKQKIEEQAKRQQERELKRQQAILLKEQQKYITEERERRRQHTTFIRQLDSRRRWEERERRKHQNLLDRLLVKEKKLQQRRKEMELLSELRRPQEDSSLSDQKPLPTLNRIPGLKLPGQAMADILQVYEFIHNFGQTLGFDMDAIPTLNTFQMALLPDCSVEAEEELLQVLTQLLITAIEDPGIPHPGRHTTLLGHAIRMGDITPQNLSEVLRIYLYANATGEVKALTGLTAERERERRVADHHQTEAEMQHTCANSKNNVYYETLHNNATYKLSEALRDKSFLALSATFKARILAFICDELLQNKAILRQVDASLEHLNQLKKERYLMDMKIRKVRVLHQRKVRAEQTEKQQALALERMQRLVEESAVNLRASPQLNDDENQQTPEKPETPKKDKESSPHPESETDKQSEPSPYKEIQPAEESDKELSPLKDLSNSMKNKEMLNNNKDECSPADNSKIDKDSVIGDCDANLSDLESEGTQPEEDEDKNLSSEELARKLEKLLKQSEQQLLQLTAGSHALRATCYGQDRYWRRYWSLGKCGGIFVEGMESAQPEIMTYHQQLENNALSGNNPPDTSKKKKKAPREKKEPTPTEVEKPNPETEAQKKEEALKSEMELKSIKSELNLSDHTQIIKYEPNVKHGACKVEGSSIKMEEKYIQQKNNEEQDMLDIEDSIPTAFLVQKPTHKPMFAAQAEPMDKPQEIVKVENVVKNETEHEDIEETKDTLVNNLEELRKMAEAVSIQLDAAKKEQEIKEEKEKVKQEPLDAASAHLQLYSKILDGKWFSILRHESSFLNNINAIEKQDLPEFCDNEHTCSEVILCQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPSNNVYADSALTMSGLDQEVIDNSFNKDGSVMEMESEDDSKEQDNDLEKELQADALKHDLLTQKAKANSLTSLGLLNFNALSTYVTCDSPPPIQMSAEEMDQLEYCKVNGLPKKVEGNFVPRELRHGWWRITETDQLRDLMDCLHPRGVRERELHNSLTHHLPTVNNKLYIEKGDILGTELCVSHLDRVIAQNGGFPSPDTSHSVLTQRRLDMQLLNMVEQLEERVAAASMQVKGWRPGRGAEAAGEAVCRARHKLQALEAHIERRYLKPPLVQRYASTSEATLGAVLQAEHGNASAPSPQHSDTTSEGKADNKGIARGLATWREAVARCNTSAQLAMLLQALEAAVAWDKSIMKANCQFCLSGDNEDQLLLCDGCDKGYHTYCFKPRMDKIPDGDWYCWECVNKARGERVCIVCGGANAHARTIPCALCSRAYHQDCHYPPLPKNPRGKWYCSQCISRAPPKKPRNTKKRDAKHRDLNASLDIDQNMVPSPAASHASTSTTAEECSGSALHTPEKHDDKLDDTLPDSENGLNHHTGELSAEEGPPEKRRALQYVGGNGALQHDETDTHMDGT*