Basic Information

Insect: Agrotis ipsilon
Gene Symbol: Baz2b
Assembly: GCA_028554685.1
Location: CM052982.1:3587662-3644532[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 5.4e-12 2.4e-08 34.4 0.0 3 75 628 703 626 705 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	5.4e-12	2.4e-08	34.4	0.0	3	75	628	703	626	705	0.89

Sequence Information

Coding Sequence: ATGGACAAGGAAGGCGGGGATGGCGGCGACGCGGCGGGCAAGCAACCCCCCGATGGCCTGCTCGATGCCGCCAACCTTTTTGGTGCATACTGGGGCCGCGATGGCAGCAGCGGCGggggcgcggcggcggcgcaggcgcaggcacAAGCCCAGGCCGCTCTGTTCGGCTTCGGCGGCGGCCGCTACCCTCCCCCTACCACCCTGGGCGTGGCAGCCAACCAGGCAGCTTCCCTTGGCCTCCATCCAGCTGCCAGTGCAGCTTGGTGGTCGATGGCATCCCACCTAGCGGCGCAAGACTACCTCGCGCGGTTACAGGCGTCAGGGTTAAACTTCCCACCCCTGGCTGACCCCTACGCCGCGCTGTCCGCCCTATCCGGGGGTCAGGGGTTGAAACAACCGCAAAAACCCGGGAAGTTGTCTAGTCGGAATGAGAGGTCAGGCAGAAGCAGTACATCATCGAGTGCGTCCACCAAGGACAAGAGCCCGTCGACCAGCAGCGCCAACTCTCAGAACATGAGATCGTCCTACGGTCTACCAAAAACCTCATCTCCGTCCGCGATGCACCACTCAGCTTCCCTCTCGAGCCTGGCATCCCTCAACAGCCTGGTGTCTGCTCCTCATCAGAGCAAGCCCAGTAGCAAGCCGTCTGCGGCGCCACAGCCAAGCAAAAagccgtcatcatcatcatcatcgagtTCTAAGGGCAAGGAGCGTGAGCTGGCGCTGTTACGCGGCGACCTTATGTTGGCGCAGGCGGCGGCTCACGGCGCGTACCACGCCGCCGTCGCTGCAGCCGCTAAGGGCAAGAATATGTCGCCTCTATATCCGTTTGGCATGCCGGGATCCGACAAGGATGGTCGGCATGGTGGCATAGACTCGCTCACTGGCTTGCCGCATACCATACTCAGtGATCCGTCATCAGTGCTGGGTGGTGTCAGATTGCCTCCGGATACGGAAATCATCAAGTATACCTCCTCATTAGCGGGGCCCAAGGCGGGCTCAGGCACAACGACTCGTGGCCGCAAGAAGACGATCTCCTTAGATCCGCCTCACGTCAGTGTTCATCCCGCCGATAGAAATGCGCCGTTACCCAGCAAACGGCCTAAGCTTGATGAGTACGGCAACTCGCGGTCGTCAGTAGAAGTGATCCGGCTGCCTAACAAACCGGACAGGGCCGGACATAACTCCATGTCCGGAACCCCGCCACCGAATCTGTCCGATTATGCAGGCATATCTCGAGAACTGCTGCAAACAATAGCTAGTCAGAGCGGCGTGTCGCTGGCCGCGCTCGAGCGACAGCTCGCCGGCTCCACAGATGCAGGTTTAAACCTGAGCACTAAGATGAGTGAGGACTCTCCTCTAGACCTGGGCGTCAAGTCCTCACCGATGGATGAGGATGCGCCGCTTAATCTTTCACTAAAACCTACTCCTGCGAGTTCGCAAGCATCAGACGCTCTCTCGCGACTGACGTCACTGAGCAGTTCGCTCAACGCGTCCTCCAGCCATGACAgaatatCTCGTCGCAAGCCCGGCGCTAAGCCCCGGCGCGTTGCTCCCGAGATGAACCCGGTACCCGACGCACCGCGACCCAAGTCCAGCGGCAGCGAGGACAGTGAATCAGTAGCGGGgtgggcagggcgtgagggcaGACCACGGAACCTCGGCAGGGGAGTCAGCAAGCCTAAGAAGAATACCGTCGCCTCACTGCTGGCACAGAGTCGAGCGCTTGGACTGAGACCGGCGCTTGCGCATCACTTGCTGGCTGAGACTGACTTGGAAAAACTAAAAGCTCTCCTCGGTGAGACTGCGAGCACAGATTCGGAGTGTCCATCGGACAGCTGTCCGTCCGACTCGGATGCATCCGACACCAGTCGTAGACCTAACGACGCCCAGCTTAGACTGCCTCTAGCGCTCGGTTGGAAACGCGTGACCGTGATCAAAGGTTTATCTCGCAACTGCAGCATCAAGGGTGACGTCACATACTCGCCTCCCGACCCGCATGCGGGCATAACCATGCGCTCCTTACATGATATACAGAACTTCCTAGAATCGAACCCATGTCCGCCGCTGTCGACGGACAACTTCAGCTTCTCAGCGCGCACAGTGCTGGGCGAGTACATCCAGCCTGCCAGTGATGTGGGAGAGCCGCTAGTCTACAATGAAAATGAGATTAATAAGAGAATAGAAGAAGCCCGTATCCTGGCCAGTGCGGGAGGTCGGCCTACCCCGCCCCCCCTGGACCGTCGCATGGAGCTGGCGCGGCTGCAGCAGGCGGCGCGGGACGCACGCCGGGACGCCTCGCATCGTGAGCGGGACCAGGCCCGTCTTGAAAGATCAGAGAAAGCGGAGCTAGCCAAACGCGAGAAGGAAGCAAGGAGTCAACAGCTACTAGAGCATATCAACAAGAATAGAACGCAGTTGACGATCGAGCCCCTCCCTACGGTACCAAAAACCGGTATCGACGAATGGAAAACACCGGAGATAGTGATGGGACCAGCCACTAAAACCAGTAAAGAACGCGTCATGCCACCGATCAGTCTCTCCCTAATACCAGTTTCTGGCCCCAAAGACCCACAGAATTCCccaataaaaactataaaattcgACCGCTCAGGATGGAAAGAAGAAATAGAGGAATACAATGCTTTAGataaaatgaaagatttcgCTGAAAAAGCGGCTTTTGATCTCCCAAAACgaaaagacaataaaaactaCGACTTCACGTTAATAAAATCAGCTGAAAAGCGCTTGAAAGCGCCCGAAAAGGAGAACAATCTAGAAAAACTAATAGAATCGTACTCAAGAATAACAGAATTTATAAACGGCTGTGATTGGTCAAAGATACAAGGGGATAAGAAAATCGAGGACCCGAAATCgattgaacaaaaatatttagacgCGAAAAACGAATTTATGTCCCAAAACCTGATGTTGATGCCGAAATCCAGTCCGAAATCTGTTCTAAAGGAGGTTATAGACTTGAGTGAGGACGATGATAATATATTGACGGATATAATGtcaaagaaaataagtaaagGGACCTTTAAAGTGGGCAAAGATGGCGCACTGTCGATCTCGGTTCATCCTTTAGGCAAGGAAACGTCTTTGGCTAAGAGACAAAAACACGAGGAGATTGAAAAGCAGAGGATTGAAGAACAGCGGAAAAGAATACAGGAGAGAGAGTTGAAGCGACAACAGGCCTTACTTCTGAAAGAACagCAAAAGTATATAACAGAGGAAAGAGAACGAAGACGCCAGCACACGACGTTCATCCGTCAGCTGGACTCCCGCAGACGCTGGGAGGAGAGAGAGAGGAGGAAGCACCAGAACCTTCTAGATAGACTGCTGGTCAAAGAGAAGAAGTTGCAACAGAGACGGAAGGAGATGGAACTGCTTTCTGAACTCAGaCGACCACAAGAAGACTCGTCACTCTCAGACCAGAAACCACTGCCGACCTTGAATAGGATCCCCGGCCTCAAGCTCCCGGGCCAGGCCATGGCCGACATACTCCAAGTATACGAGTTTATACATAACTTCGGACAAACACTCGGATTTGATATGGATGCCATCCCAACTCTGAATACGTTCCAAATGGGCCTGTTGCCCGACTGCAGCGTGGAGGCCGAGGAGGAACTGCTACAAGTGCTCACACAACTACTTATCACTGCTATTGAGGACCCAGGTATCCCACACCCAGGTCGTCATACCACGTTGCTTGGGCATGCGATCCGCATGGGTGACATCACGCCACAGAATCTAAGCGAGGTGCTCAGAATATACCTCTACGCCAATGCTACTGGGGAAGTCAAGGCTCTTACTGGATTAACAGCGGAGCGCGAGCGTGAGCGCCGCGTGGCCGACCATCACCAGACGGAGGCTGAGATGCAGCACACGTGTGCCAACTCCAAGAACAACATCTACTACGAGACTCTACACAATAACCCTACTTATAAACTATCAGAGGCTCTCCGCGACAAGTCATTCCTGGCCCTCAGTGCCACCTTCAAGGCTCGTATCCTGGCCTTCATCTGCGACGAGCTGCTGCAGAACAAGGCAGTGCTGAGGCAGGTGGACGCCAGCCTCGAGCATCTCAACCACTTGAAGAAGGAGAGATACCTTATGGATATGAAGATTAGGAAGGTCAGAGTCCTCCACCAACGCAAAGTGCGAGCAGAACAGACGGAGAAGCAGCAGGCGTTAGCACTGGAGAGGATGCAGAGGTTGGTAGAGGAGAGTGCTGCCAACCTGAGAGCGTCGCCACAACTTAATGAAGACGAAAACCAACATACCCCAGAAAAATCCGAAACGCCTAAGAAAGACAAAGAATCATCACCACCACCAGAAAGTGAAACAGACAAGCAATCCGAACCATCACCTTACAAGGAGAGCCAACCAGCCGAGGAGAGCGACAAGGAACTATCGCCCATAAAGGACCTCTCCAACAGTATGAAGAATAAAGAGATGTTGAATAACAATAAGGACGAATGTTCCCCGGCAGATAACTCGAAGATTGATAAGGATAGTGTGATTGGGGATTGTGAGGATCATTTGAGCGATTTAGAGAGTGAGGGCACGCAGCCGGAGGAGGATGAAGACAAGAACTTATCATCTGAGGAGCTGGCTCGCAAGCTGGAGAAGCTACTGAAGCAGTCCGAACAACAGTTACTGCAGCTCACGGCTGGGTCGCACGCGCTCAGGGCCACGTGTTATGGACAGGATAGGTACTGGCGCCGTTACTGGTCGCTAGGCAAGTGCGGCGGTATCTTCGTGGAGGGCATGGAGTCAGCCCAGCCGGAGATCATGTCGTACCACCAGCAGCTGGAGAACAACGCACTCAGCGGGAACACGCAGCCTGACACCGGCAAGAAGAAAAAGAAGGCTCCTCGAGAGAAGAAAGAAGCCACTCCTCCCGAATGTGAACAGCCCACACCGGAAACGGAAGCCCAGAAGAAAGAGGAAGCTCTGAAGAGTGAGATGGAGCTGAAGAGCATCAAGTCAGAGTTGAACCTGAGTGATCACACGCAGATCATCAAGTACGAGCCTAATGTCAAGCATGGCGCTTGTAAGGTCGAAGGCTCCTCAataaaaatggaagaaaaatacATCCAGCAGAAGAACAACGAAGAGCAAGACATGCTCGACATAGAAGACTCTATACCTACAGCCTTTTTAGTTCAGAAACCGACCCACAAGCCAATGTTCGCAGCCCAAGCCGAACCAATGGACAAACCACAAGAAATAGTCAAGGTCGAAAACGTAGTCAAAAACGAGACAGAACAAGAGGAATTGGAAGAAACTAAGGACACATTAGTCAATAATTTAGAAGAATTACGCAAAATGGCTGAAGCAGTCTCCATACAGCTCGACGCAGCAAAGAAAGAGCAAGagataaaagaagaaaaggAAAGAATCAAGCAAGAACCAATAGACGCAGCGAACGCACATTTACAACTATACTCCAAAATGCTAGACGGAAAATGGTTCTCAATTCTCCGTCACGAAAGCTCATTTTTGAACAACATTAACGAGGTTGAAAAGCAAGATTTGCCGGAATTCTGTGATAACGAACACACTTGTTCTGAGGTCATATTGTGTCAAGGTCATAAGTGGGATGTTTCTAATAATCTTCACTTGTTAAATGATCCGAGTTTGTTCACCTTGAATAGTATGGTGACGAGTGTACAAGTGCCGTCGAACAATGTGTATGCTGATTCCAGTCTGACTATGTCTGGTTTGGATCAGGAGTTAATTGATAATAGCTTTAATAAGGATGGAACTGTTCAGGAGGTGGAAACGGAAGAGGATAGTAAGGAACAGGACAACGATCTAGAAAAAGAACTCCAAGCCGATGCCCTAAAGCATGACTTACTAACTCAAAAGGCCAAAGCCAACTCCCTCACGAGCCTGGGCCTGTTGAACTTCAACGCCCTGTCCACCTACGTCACGTGCGACAGTCCACCTCCCATACAGATGTCCGCCGACGAAATGGACCAGCTGGAGTACTGTAAGGTTAATGGACTGCCGAAGAAGGTCGAGGGGAACTACGTGCAGAGGGAGTTGAGacaCGGCTGGTGGCGTATCACAGAAACGGATCAGCTCCGTGATCTCATGGATTCTCTACATCCGCGCGGAGTGAGGGAGAGGGAACTACATGCGTCCCTCACCAACCATCTGCCTACTGTTAATAATAagCTCTACATAGAAAAAGGCGACATCTTGGGCACAGAGCTATGTGTGTCCCACCTGGATCGAGTGATCGCTCAGAACGGCGGGTTTCCCTCACCGGACACGTCGCACTCCGCGCTCACACAACGAAGATTAGACATGCAGTTGCTGAATATGGTGGAACAACTAGAAGAGCGTATAGCAGCGGCGTCAATGCAGGTAAAAGGCTGGCGACCAGCCCGCTCCCCGGACCGCGGTCCTAGTGAGCCAGTGGCCCGCGCACGACACAAGCTACAAGCACTAGAGGCCCACATCGAGCGCAGATACCTCAAGCCGCCGCTCGTGCAAAGGTACGCTAGCACAACAGAAGCGACGTTGGGTGCAGTGCTACAAGCTGAGCACGGTAATGCGTCGGCGCCGTCGCCGCAGAACACTGATAGTGCTAGCGAGGGGAAAGCGGACAACAAAGGCATAGCCCGCGGTCTGGCAACGTGGCGCGAGGCAGTCGCTCGCTGCAACACGTCAGCCCAGCTGGCCATGATGGTGCAGGCCCTGGAGGCAGCAGTCGCCTGGGACAAGAGCATCATGAAGGCGAACTGTCAGTTTTGTCAGTGCGGTGACAATGAGGACCTACTACTACTGTGCGACGGCTGTGATAAGGGTTATCACACGTATTGCTTCAAACCCACGATGGATAAGATACCTGATGGAGACTGGTATTGCTGGGAATGCGTGAACAAAGCACGTGGTGAACGAGTCTGCATTGTATGCGGCGGCGCCAACGCTAACACTCGCACCATACCCTGCGCGCTGTGCTCGCGGGCATACCATCAGGACTGCCACTATCCACCACTCTTAaagAATCCCCGCGGTAAATGGTACTGTTCTCAGTGCATATCTCGCGCGCCGCCGAAGAAGCCGCGCAACACTAAGAAGAGAGACGCCAAACACCGCGACTTGAACGCCAGCCTTGATCTCGACCAGAATATGGTGCCTAGTCCAGCAGCATCCCACGCCTCCACATCAACTACAGCTGAAGAGTGTTCAGGCTCAGCGCTGCACACACCTGAGAAACATGACGACAAGATGGATGAAACGCTACCAGATAGTGAGAACGGACTCAATCATCATACGGGTGAACTGAGTGCGGAGGAAGGTCCTCCAGAGAAACGTCGCGCGCTACAGTATGTGGGTGGCAACGGAGCTCTGCAACATGATGAAACTGATACACAGATAGATGGCGAAGACCGTGAGATCGAGCCCGCGCCGCTAGTATCTCGAGCcaagaaagaaaagaatacAGCAAAGAAATTGCAAAAAGATCTACAATTCTGCAAGAACCTTCTGAACGAGATGGAGTGTCACGAGCACGCATGGCCGTTCCTGTTGCCAGTGAACACTAAACAGTTCCCACAATACAAGAAGGTCATCAAGTGTCCCATGGACCTCTCAACGATCAAACGGAAGCTACAGGATAAcatCTACAAATGCAAAGAAGAATTCGCCTCCGACGTGCGCCTCATATTCAGCAACTGCGAAGTTTTTAACGAAGATGACAGTCCTGTGGGACGTGCTGGACATAACATGCGACAGTTCTTCGACGACCGGTGGACGCAGATCTGA
Protein Sequence: MDKEGGDGGDAAGKQPPDGLLDAANLFGAYWGRDGSSGGGAAAAQAQAQAQAALFGFGGGRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPLADPYAALSALSGGQGLKQPQKPGKLSSRNERSGRSSTSSSASTKDKSPSTSSANSQNMRSSYGLPKTSSPSAMHHSASLSSLASLNSLVSAPHQSKPSSKPSAAPQPSKKPSSSSSSSSKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGSDKDGRHGGIDSLTGLPHTILSDPSSVLGGVRLPPDTEIIKYTSSLAGPKAGSGTTTRGRKKTISLDPPHVSVHPADRNAPLPSKRPKLDEYGNSRSSVEVIRLPNKPDRAGHNSMSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSTDAGLNLSTKMSEDSPLDLGVKSSPMDEDAPLNLSLKPTPASSQASDALSRLTSLSSSLNASSSHDRISRRKPGAKPRRVAPEMNPVPDAPRPKSSGSEDSESVAGWAGREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHHLLAETDLEKLKALLGETASTDSECPSDSCPSDSDASDTSRRPNDAQLRLPLALGWKRVTVIKGLSRNCSIKGDVTYSPPDPHAGITMRSLHDIQNFLESNPCPPLSTDNFSFSARTVLGEYIQPASDVGEPLVYNENEINKRIEEARILASAGGRPTPPPLDRRMELARLQQAARDARRDASHRERDQARLERSEKAELAKREKEARSQQLLEHINKNRTQLTIEPLPTVPKTGIDEWKTPEIVMGPATKTSKERVMPPISLSLIPVSGPKDPQNSPIKTIKFDRSGWKEEIEEYNALDKMKDFAEKAAFDLPKRKDNKNYDFTLIKSAEKRLKAPEKENNLEKLIESYSRITEFINGCDWSKIQGDKKIEDPKSIEQKYLDAKNEFMSQNLMLMPKSSPKSVLKEVIDLSEDDDNILTDIMSKKISKGTFKVGKDGALSISVHPLGKETSLAKRQKHEEIEKQRIEEQRKRIQERELKRQQALLLKEQQKYITEERERRRQHTTFIRQLDSRRRWEERERRKHQNLLDRLLVKEKKLQQRRKEMELLSELRRPQEDSSLSDQKPLPTLNRIPGLKLPGQAMADILQVYEFIHNFGQTLGFDMDAIPTLNTFQMGLLPDCSVEAEEELLQVLTQLLITAIEDPGIPHPGRHTTLLGHAIRMGDITPQNLSEVLRIYLYANATGEVKALTGLTAERERERRVADHHQTEAEMQHTCANSKNNIYYETLHNNPTYKLSEALRDKSFLALSATFKARILAFICDELLQNKAVLRQVDASLEHLNHLKKERYLMDMKIRKVRVLHQRKVRAEQTEKQQALALERMQRLVEESAANLRASPQLNEDENQHTPEKSETPKKDKESSPPPESETDKQSEPSPYKESQPAEESDKELSPIKDLSNSMKNKEMLNNNKDECSPADNSKIDKDSVIGDCEDHLSDLESEGTQPEEDEDKNLSSEELARKLEKLLKQSEQQLLQLTAGSHALRATCYGQDRYWRRYWSLGKCGGIFVEGMESAQPEIMSYHQQLENNALSGNTQPDTGKKKKKAPREKKEATPPECEQPTPETEAQKKEEALKSEMELKSIKSELNLSDHTQIIKYEPNVKHGACKVEGSSIKMEEKYIQQKNNEEQDMLDIEDSIPTAFLVQKPTHKPMFAAQAEPMDKPQEIVKVENVVKNETEQEELEETKDTLVNNLEELRKMAEAVSIQLDAAKKEQEIKEEKERIKQEPIDAANAHLQLYSKMLDGKWFSILRHESSFLNNINEVEKQDLPEFCDNEHTCSEVILCQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPSNNVYADSSLTMSGLDQELIDNSFNKDGTVQEVETEEDSKEQDNDLEKELQADALKHDLLTQKAKANSLTSLGLLNFNALSTYVTCDSPPPIQMSADEMDQLEYCKVNGLPKKVEGNYVQRELRHGWWRITETDQLRDLMDSLHPRGVRERELHASLTNHLPTVNNKLYIEKGDILGTELCVSHLDRVIAQNGGFPSPDTSHSALTQRRLDMQLLNMVEQLEERIAAASMQVKGWRPARSPDRGPSEPVARARHKLQALEAHIERRYLKPPLVQRYASTTEATLGAVLQAEHGNASAPSPQNTDSASEGKADNKGIARGLATWREAVARCNTSAQLAMMVQALEAAVAWDKSIMKANCQFCQCGDNEDLLLLCDGCDKGYHTYCFKPTMDKIPDGDWYCWECVNKARGERVCIVCGGANANTRTIPCALCSRAYHQDCHYPPLLKNPRGKWYCSQCISRAPPKKPRNTKKRDAKHRDLNASLDLDQNMVPSPAASHASTSTTAEECSGSALHTPEKHDDKMDETLPDSENGLNHHTGELSAEEGPPEKRRALQYVGGNGALQHDETDTQIDGEDREIEPAPLVSRAKKEKNTAKKLQKDLQFCKNLLNEMECHEHAWPFLLPVNTKQFPQYKKVIKCPMDLSTIKRKLQDNIYKCKEEFASDVRLIFSNCEVFNEDDSPVGRAGHNMRQFFDDRWTQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01026216;
90% Identity: iTF_01118339;
80% Identity: -