Basic Information

Insect: Ophonus ardosiacus
Gene Symbol: topi
Assembly: GCA_943138245.1
Location: CALPBP010001885.1:53746-56575[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00024 0.045 15.8 1.8 2 21 131 150 130 151 0.94

2 13 0.0001 0.019 17.0 3.4 1 20 176 195 176 198 0.95

3 13 0.011 1.9 10.7 0.9 2 23 205 226 205 226 0.95

4 13 0.12 22 7.3 0.5 2 21 245 264 244 265 0.91

5 13 0.00082 0.15 14.2 0.9 1 23 332 354 332 354 0.99

6 13 0.39 71 5.7 3.9 2 22 397 417 396 420 0.86

7 13 0.29 52 6.2 0.1 1 23 523 546 523 546 0.96

8 13 0.071 13 8.1 1.1 1 23 550 572 550 572 0.93

9 13 7.1e-07 0.00013 23.8 2.4 1 23 578 600 578 600 0.98

10 13 0.024 4.5 9.5 0.2 1 23 606 631 606 631 0.96

11 13 0.43 79 5.6 3.3 1 23 637 659 637 659 0.86

12 13 3.8e-05 0.0069 18.4 0.9 3 23 667 687 665 687 0.97

13 13 2e-06 0.00037 22.4 0.3 1 23 693 716 693 716 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00024	0.045	15.8	1.8	2	21	131	150	130	151	0.94
2	13	0.0001	0.019	17.0	3.4	1	20	176	195	176	198	0.95
3	13	0.011	1.9	10.7	0.9	2	23	205	226	205	226	0.95
4	13	0.12	22	7.3	0.5	2	21	245	264	244	265	0.91
5	13	0.00082	0.15	14.2	0.9	1	23	332	354	332	354	0.99
6	13	0.39	71	5.7	3.9	2	22	397	417	396	420	0.86
7	13	0.29	52	6.2	0.1	1	23	523	546	523	546	0.96
8	13	0.071	13	8.1	1.1	1	23	550	572	550	572	0.93
9	13	7.1e-07	0.00013	23.8	2.4	1	23	578	600	578	600	0.98
10	13	0.024	4.5	9.5	0.2	1	23	606	631	606	631	0.96
11	13	0.43	79	5.6	3.3	1	23	637	659	637	659	0.86
12	13	3.8e-05	0.0069	18.4	0.9	3	23	667	687	665	687	0.97
13	13	2e-06	0.00037	22.4	0.3	1	23	693	716	693	716	0.98

Sequence Information

Coding Sequence: ATGAGCTATCAAGACAATATATTGTTAAAAGTGCATCATGTAGAAAGCAATGGTATGATAAATTCTTCTTTTCAAGTAGAAGTTGATACAAAGGATAAGGTAGTTTCAATCACAGGACTTAACGAACATAAcgttaatattgaaaaattgttgATGAATTGGGAAACTTCTgatgataatataaattttgaatatcacACTTTTGTAGAAGATAAAAGCCCTACTATCAAATTAATCAAAATCGGAGACTTGAATGAATTAAATCCAATGAATTATATTACTCATATAAACTCAAGTGTTAACAACAATGTCGATATCCAAAAGTATGTGTTCAATGAAACGAAGAAAAAGCAGGTAAAACAGTTAAATTTACCCGATACTAGTACAAtttcatgtcaaaattgtgaTACCTCTTTTCCCACAAAATATCAGTATCAACGTCATCAGTGTGAATTTAACGCCGAAAAAGTTGTTCTCAAGCCTGAAATTGCTGGTAAAGATGTAGATAAAGCCTCTAGATTGCGTTTTGAATGCGATGTTTGCAAAAAATCTTTTGTTAGCAACAATAATTTAGAGCGTCATAAAAGTTgccatacaaaaagaaatagtAATGTTTGTGAGTTCTGTAGCAAAACGTTTGTTAGTGAAAATCGACTTAAAATCCACAAAGAAAATCACTGTAAAAAGGCGGGAGATACAGCTAAATTTTATAGAAGTGACGTGGCAGTGTGGAGATGTGAACAATGTAAACAAGTATTTGCTACTCACGAAAGCGGgaataaacatataaaacaatGCACAACTATTGAACCATCGACATCATCAGTTGTTAAAGCTaatgataaacaaataaacgaaaataatataataaacattaaaagtaTCTTTGAAGAAAATAACTTTgattctaattttgaaaaagcTATAACTAATCAACCTGGCTTTTACAAAGAAACTACTATTACTTTAGAGAAAATCATTACCGAAATGTTGTATCAATGTGAATTTTGTAACCGAACTTACGCCGAAAAAATGGCGGTTTTGAATCATCAAAAAACTCATAcaactgaaaaaaattatgaatgtatTTTCTGTGATCAATACTTTAATAGTTATTGCCAAGCCACTGTTCATTGGCAAAGCAAATGCAACaacgaatcaaatttattttacttgccaaaaatgatttattGTGAACATTGCGACCGAGGATTTAAATCtcatgaaattttatataatcataaaaacaaaaagaaacatTTTAGTCCTAAAATTCacaacaaattaaaagaaaaaaatgaagtGAAATCTGAAAACGAAAAAGCAATAGCTAAATTAATAGAAAACATGATCACCAAGCTAGATCAAAACGTCCAATTGTCCGCCATTGATAACGAAATAGACCCGAAAGAAAACGATGAAAATAGCTTGTTGGTGCCTGTTGGTTCTGTTAAACTAGAAAATGATGAAGAAAACCCCGAAAATGGGAAGAAAAAACGTGGGCGCAAAcgaaaatggcaaaaaactgaaatgaaaaataaaatcattaatgaAGAAGGATGTCAATATCAGTGTGAAAGATGTGCTGCTGTTTTCGAAACCATTGCTACTTTAGATTTGCACAAAGACACTACTCATGCTAGCACCTACAAATGCGAGCAATGTGGGCAGATTGTTCACAGTGCCAAAGCCCTAATGATTCACTGCCGTGCCCATCAATGCCTAAAACCTTATGTCTGCGACCAATGTGGTCGTAGTTATTCCCAAACTTCTCACCTTTGGCAGCATATGAGATTCCATCAAGgTATCAAGCCATTCGCTTGCCCTCACGAAGGCTGTGAAGCCCGCTACACAATTCGCCCTGATTTAAAAGATCACATCCGAAAAGTTCATACTCGAGAACGTCCATTTAAATGCTCAGTCTGCCAGAAATGCTTTTTAACTGGATCTGTTTATTATCAACACCGTTTGATTCATACAAACGATCGAAGATATGGCTGTGAATTTTGTAACAAACGTTTTTTTCGAGCTGACGCTTTGAATAATCATCGAAGAATTCATACGGATGAACGTCCATACCCTTGTCCAGTCTGCGGACGGGAATTTAGACAAAAAGGAGATAGAAATAAGCATGTTCGAACTCAGCATTCTATGTAA
Protein Sequence: MSYQDNILLKVHHVESNGMINSSFQVEVDTKDKVVSITGLNEHNVNIEKLLMNWETSDDNINFEYHTFVEDKSPTIKLIKIGDLNELNPMNYITHINSSVNNNVDIQKYVFNETKKKQVKQLNLPDTSTISCQNCDTSFPTKYQYQRHQCEFNAEKVVLKPEIAGKDVDKASRLRFECDVCKKSFVSNNNLERHKSCHTKRNSNVCEFCSKTFVSENRLKIHKENHCKKAGDTAKFYRSDVAVWRCEQCKQVFATHESGNKHIKQCTTIEPSTSSVVKANDKQINENNIINIKSIFEENNFDSNFEKAITNQPGFYKETTITLEKIITEMLYQCEFCNRTYAEKMAVLNHQKTHTTEKNYECIFCDQYFNSYCQATVHWQSKCNNESNLFYLPKMIYCEHCDRGFKSHEILYNHKNKKKHFSPKIHNKLKEKNEVKSENEKAIAKLIENMITKLDQNVQLSAIDNEIDPKENDENSLLVPVGSVKLENDEENPENGKKKRGRKRKWQKTEMKNKIINEEGCQYQCERCAAVFETIATLDLHKDTTHASTYKCEQCGQIVHSAKALMIHCRAHQCLKPYVCDQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCQKCFLTGSVYYQHRLIHTNDRRYGCEFCNKRFFRADALNNHRRIHTDERPYPCPVCGREFRQKGDRNKHVRTQHSM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00029613;
90% Identity: iTF_00767543; iTF_00769114;
80% Identity: -