Basic Information

Insect: Harpalus rubripes
Gene Symbol: topi
Assembly: GCA_963082715.1
Location: OY720457.1:54553040-54555413[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00029 0.072 15.8 1.8 2 21 131 150 130 151 0.94

2 13 0.00012 0.031 17.0 3.4 1 20 176 195 176 198 0.95

3 13 0.012 3.1 10.7 0.9 2 23 205 226 205 226 0.95

4 13 0.14 36 7.3 0.5 2 21 245 264 244 265 0.91

5 13 0.0025 0.63 12.9 0.8 1 23 332 354 332 354 0.99

6 13 0.45 1.2e+02 5.7 3.9 2 22 397 417 396 420 0.86

7 13 0.56 1.4e+02 5.4 0.1 1 23 525 548 525 548 0.96

8 13 0.083 21 8.1 1.1 1 23 552 574 552 574 0.93

9 13 8.4e-07 0.00021 23.8 2.4 1 23 580 602 580 602 0.98

10 13 0.029 7.3 9.5 0.2 1 23 608 633 608 633 0.96

11 13 0.5 1.3e+02 5.6 3.3 1 23 639 661 639 661 0.86

12 13 4.4e-05 0.011 18.4 0.9 3 23 669 689 667 689 0.97

13 13 2.4e-06 0.0006 22.4 0.3 1 23 695 718 695 718 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00029	0.072	15.8	1.8	2	21	131	150	130	151	0.94
2	13	0.00012	0.031	17.0	3.4	1	20	176	195	176	198	0.95
3	13	0.012	3.1	10.7	0.9	2	23	205	226	205	226	0.95
4	13	0.14	36	7.3	0.5	2	21	245	264	244	265	0.91
5	13	0.0025	0.63	12.9	0.8	1	23	332	354	332	354	0.99
6	13	0.45	1.2e+02	5.7	3.9	2	22	397	417	396	420	0.86
7	13	0.56	1.4e+02	5.4	0.1	1	23	525	548	525	548	0.96
8	13	0.083	21	8.1	1.1	1	23	552	574	552	574	0.93
9	13	8.4e-07	0.00021	23.8	2.4	1	23	580	602	580	602	0.98
10	13	0.029	7.3	9.5	0.2	1	23	608	633	608	633	0.96
11	13	0.5	1.3e+02	5.6	3.3	1	23	639	661	639	661	0.86
12	13	4.4e-05	0.011	18.4	0.9	3	23	669	689	667	689	0.97
13	13	2.4e-06	0.0006	22.4	0.3	1	23	695	718	695	718	0.98

Sequence Information

Coding Sequence: ATGAGCTATCAAGACAATATATTGTTAAAAGTGCATCACGTAGAAAGCAATGGTATGATAAATTCTTCTTTTCAAGTTGAAATTGATACAAAGGATAAGGTAGTTTCAATCACAGGACTTAACGAACCCAACGttaatattgataaattgttGATGAATTGGGATACTTCTGatgataatataaattttgaatatcacACTTTTGTAGAAGATAAAAGCCctactataaaattaatcaaaatcgGAGATTTGAATGAATTGAATCCAATGAATTATATTACTCATATAAACTCAAGTGTTAACAACAATGTCGATATCCAAAAGTATGTTTTCAATGAAACGAAGAAACACCaggtaaaacaattaaatttaccCGATACAAGTACAATTTCATGTCAAAACTGTGATACCTCTTTTCCCACAAAATATCAGTATCAACGTCATCAGTGTGAATTTAACGCCGAAAAAGTTGTTCTGAAGCCAGAAATTGCTGGTAAAGATGTAGATAAAGCCTCTAGATTGCGATTTGAATGCGATGTTTGCAAAAAATCTTTTGTTAGCAACAATAATTTAGAGCGTCATAAAAGTTGCCATACTAAACGAAATAGTAATGTTTGTGAGTTCTGTAGCAAAACGTTTGTTAGTGAAAATCGACTTAAAATTCacaaagaaaatcactgtaaaAAGGCGGGAGATACAGCTAAATTTTATAGGAGTGACGTGGCAGTTTGGCGGTGTGAACAATGTAAACAAGTATTTGCTACTCACGAAAGcggaaataaacatataaaacaaTGCACAACTGTTGAACCATCGACATCATCAGTTGTTAAAGCtgatgataaacaaataaacgaaaataatataataaacattaaaagtatctttgaagaaaataactttgattctaattttgaaaaagctATAACTAATCAACCAGGCTTTTACAAAGAAACTACTATCACTTTAGAGAAAATTATAACCGAAATGTTGTATCAATGTGAATTTTGTAACCGAACTTACGCCGAAAAACTGGCGGTTTTGAATCATCAAAAAACCCATACAActgaaaaaaattatgaatgtatTTTCTGTGATCAACACTTTAATAGTTATTGCCAAGCCACTGTTCATTGGCAAAGTAAATGCAACAacgaatcaaatttattttatttacccaAAATGATATATTGTGAACATTGTGACCGAGGATTTAAATctcatgaaattttatataatcataaaaacaaaaagaaacatttcaGTCCTAAAATTCACAACAAGCAAAAAGAAAAAACTGAAGAAGTAAAATCAGAAAATGAAAAGGCAATAGccaaattaatagaaaatatgaTTACCAAGCTAGATCAAAACGTACAATTGTCCGCCATTGATAACGAAATAGACCCGAAAGAAAATGATGATAATAGCTTGTTGGTACGTGTTGGTTCTGTTAAACTAGAAAACGATGAAGAAAACAATCCCgaaaatgggaagaaaaaacGAGGCCGCAAACGAAAATGGCAAAAAACagaaatgaaaaacaaaatcattAATGAAGAAGGATGTCAGTATCAGTGTGAAAGATGTGCTGCAATTTTTGAAACTATCGCTACTTTAGATGTGCACAAAGATACTACTCATGCCAGTACTTACAAATGCGAACAATGTGGAcagATTGTTCACAGTGCCAAAGCCCTAATGATTCACTGCCGTGCCCACCAATGTCTAAAACCTTATGTCTGCGATCAATGTGGTCGTAGTTATTCCCAAACTTCTCACCTTTGGCAACATATGAGATTCCATCAAGGCATCAAACCATTCGCTTGTCCTCACGAAGGGTGCGAAGCCCGATATACAATCCGTCCCGATTTAAAAGATCATATCCGAAAAGTTCATACTCGAGAACGTCCTTTTAAATGCTCAGTCTgccaaaaatgttttttaactggatctgtttattatcaacatcgGTTGATTCATACAAATGATCGAAGATATGGCTGTGAATTTTGTAATAAACGGTTTTTTCGAGCTGATGCTTTAAATAATCATCGAAGAATTCATACAGATGAGCGCCCGTATCCTTGTCCAGTTTGTGGACGGGAATTTAGACAGAAAGGAGATAGAAATAAGCATGTTCGCACTCAACATTCAATGTAA
Protein Sequence: MSYQDNILLKVHHVESNGMINSSFQVEIDTKDKVVSITGLNEPNVNIDKLLMNWDTSDDNINFEYHTFVEDKSPTIKLIKIGDLNELNPMNYITHINSSVNNNVDIQKYVFNETKKHQVKQLNLPDTSTISCQNCDTSFPTKYQYQRHQCEFNAEKVVLKPEIAGKDVDKASRLRFECDVCKKSFVSNNNLERHKSCHTKRNSNVCEFCSKTFVSENRLKIHKENHCKKAGDTAKFYRSDVAVWRCEQCKQVFATHESGNKHIKQCTTVEPSTSSVVKADDKQINENNIINIKSIFEENNFDSNFEKAITNQPGFYKETTITLEKIITEMLYQCEFCNRTYAEKLAVLNHQKTHTTEKNYECIFCDQHFNSYCQATVHWQSKCNNESNLFYLPKMIYCEHCDRGFKSHEILYNHKNKKKHFSPKIHNKQKEKTEEVKSENEKAIAKLIENMITKLDQNVQLSAIDNEIDPKENDDNSLLVRVGSVKLENDEENNPENGKKKRGRKRKWQKTEMKNKIINEEGCQYQCERCAAIFETIATLDVHKDTTHASTYKCEQCGQIVHSAKALMIHCRAHQCLKPYVCDQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCQKCFLTGSVYYQHRLIHTNDRRYGCEFCNKRFFRADALNNHRRIHTDERPYPCPVCGREFRQKGDRNKHVRTQHSM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00029613;
90% Identity: iTF_01105048;
80% Identity: -