Basic Information

Insect: Harpalus rufipes
Gene Symbol: topi
Assembly: GCA_951394225.1
Location: OX596280.1:45182697-45185077[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00024 0.053 15.8 1.8 2 21 131 150 130 151 0.94

2 13 0.0001 0.023 17.0 3.4 1 20 176 195 176 198 0.95

3 13 0.011 2.3 10.7 0.9 2 23 205 226 205 226 0.95

4 13 0.12 27 7.3 0.5 2 21 245 264 244 265 0.91

5 13 0.00082 0.18 14.2 0.9 1 23 331 353 331 353 0.99

6 13 0.39 85 5.7 3.9 2 22 396 416 395 419 0.86

7 13 0.27 59 6.2 0.1 1 23 524 547 524 547 0.96

8 13 0.071 16 8.1 1.1 1 23 551 573 551 573 0.93

9 13 7.1e-07 0.00016 23.8 2.4 1 23 579 601 579 601 0.98

10 13 0.024 5.3 9.5 0.2 1 23 607 632 607 632 0.96

11 13 0.43 94 5.6 3.3 1 23 638 660 638 660 0.86

12 13 3.8e-05 0.0083 18.4 0.9 3 23 668 688 666 688 0.97

13 13 2e-06 0.00044 22.4 0.3 1 23 694 717 694 717 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00024	0.053	15.8	1.8	2	21	131	150	130	151	0.94
2	13	0.0001	0.023	17.0	3.4	1	20	176	195	176	198	0.95
3	13	0.011	2.3	10.7	0.9	2	23	205	226	205	226	0.95
4	13	0.12	27	7.3	0.5	2	21	245	264	244	265	0.91
5	13	0.00082	0.18	14.2	0.9	1	23	331	353	331	353	0.99
6	13	0.39	85	5.7	3.9	2	22	396	416	395	419	0.86
7	13	0.27	59	6.2	0.1	1	23	524	547	524	547	0.96
8	13	0.071	16	8.1	1.1	1	23	551	573	551	573	0.93
9	13	7.1e-07	0.00016	23.8	2.4	1	23	579	601	579	601	0.98
10	13	0.024	5.3	9.5	0.2	1	23	607	632	607	632	0.96
11	13	0.43	94	5.6	3.3	1	23	638	660	638	660	0.86
12	13	3.8e-05	0.0083	18.4	0.9	3	23	668	688	666	688	0.97
13	13	2e-06	0.00044	22.4	0.3	1	23	694	717	694	717	0.98

Sequence Information

Coding Sequence: ATGAGCTATCAagacaatatattgttaaaagTGCATCACGTAGAAAGCAATGGTATGATAAATTCTTCTTTTCAAGTAGAAGTTGATACAAAAGATAAGGTAGTTTCAATCACAGGACTTAACGAACCTAACGTTAATATTGATAAATTGTTGATGAATTGGGATACTTCTgatgataatataaattttgaatatcacACTTTTGTAGAAGATAAAAGCCCTACCATAAAATTAATCAGAATCGGAGACCTGAATGAATTAAATCCAATGAATTATATTACCCATATAAACTCAAGTGTTAACAATAATGTCGATATCCAAAAGTATGTTTTCAATGAAACGAAGAAACAGCAggtaaaacaattaaatttacccGATACAAGTACAATTTCATGTCAAAATTGTGATACCTCTTTTCCCACAAAATATCAGTATCAACGTCATCAGTGTGAATTTAATGCCGAAAAAGTTGTTTTGAAGCCAGAAATTGTTGGCAAAGATATAGATAAAGCCTCTAGATTGCGATTTGAATGCGATGTTTGCAAAAAATCTTTTGTTAGCAACAATAATTTAGAGCGTCATAAAAGTTGCCATACTAAAAGAAATAGTAATGTTTGTGAGTTCTGTAGCAAAACGTTTGTTAGTGAAAATCGGCTTAAAATCCACAAAGAAAATCACTGTAAAAAGGCGGGAGATACAGCTAAATTTTATAGGAGTGACGTGGCTGTTTGGCGGTGTGAACAATGTAAACAAGTATTTGCTACTCACGAAAGCGGaaataaacatataaaacaATGTACTACTGTTGAACCATTGACATCAGTTGTTAAAGCTgatgataaacaaataaacgaaaataatataataaacattaaaagtatttttgaagaaaataactTTGATTCTAATTTTGAAAAAGCTATAACAAATCAACCAGGCTTTTACAAAGAAAGTACTATCACATTAGAGAAAATCATAACCGAAATGTTATATCAATGTGAATTTTGTAACCGAACTTACGCCGAGAAAATGGCGGTTCTAAATCATCAAAAAACTCATacaacagaaaaaaattacgaaTGCATTTTCTGTGATCAACACTTTAACAGTTATTGCCAAGCCACTGTTCATTGGCAAAGCAAATGCAACAAcgaatcaaatttattttacttacctaAAATGATATATTGTGAACATTGCGACCGAGGATTTAAATCTCATGAGATCTTATACAatcataaaaacaaaaagaaacacTTTAGTCCAAAAATTCACaacaaacaaaaagaaaaaaacgaAGAAGTGAAATCAGAAAACGAAAAAGCAATAGCCAAATTAATAGAAAACATGATCACCAAGTTAGATCAAAACGTACAATTGTCCGCCATTGATAACGAAATAGATCCGaaagaaaatgatgaaaatagCTTGTTGGTGCCAGTTGGTTCtgttaaattagaaaatgatgAAGAAAACAACCCAGAAAATGGGAAGAAAAAACGGGGACGCAAACGAAAATGGCAAAAAAcggaaatgaaaaataaaataattaatgaagaAGGTTGTCAGTATCAATGTGAAAGATGTGCTGCTGTTTTTGAAACCATCGTTACTTTAGATGTGCATAAAGATACTACTCATGCCAGTACTTATAAATGCGAGCAATGTGGACAGATTGTTCACAGTGCCAAAGCCCTAATGATTCACTGCCGCGCTCACCAATGCCTAAAACCTTATGTCTGCGACCAATGCGGTCGTAGTTATTCCCAAACTTCCCACCTTTGGCAACATATGAGATTCCATCAAGgtATCAAACCCTTCGCATGTCCCCACGAAGGCTGCGAAGCTCGCTATACAATTCGTCCTGATTTGAAAGATCACATCCGAAAAGTTCATACTCGAGAACGTCCATTTAAATGCTCAGTCTGCCAAAAGTGCTTTTTAACTGGATCTGTTTATTATCAACATCGTTTGATTCACACAAATGATCGACGATATGGTTGTGAATTTTGTAATAAACGGTTTTTTCGAGCTGATGCTTTGAATAATCATCGAAGAATTCATACAGATGAACGTCCGTATCCTTGTCCCGTTTGCGGACGGGAGTTTAGACAGAAAGGAGATAGAAATAAGCATGTTCGTACTCAGCATTCTGTGTAA
Protein Sequence: MSYQDNILLKVHHVESNGMINSSFQVEVDTKDKVVSITGLNEPNVNIDKLLMNWDTSDDNINFEYHTFVEDKSPTIKLIRIGDLNELNPMNYITHINSSVNNNVDIQKYVFNETKKQQVKQLNLPDTSTISCQNCDTSFPTKYQYQRHQCEFNAEKVVLKPEIVGKDIDKASRLRFECDVCKKSFVSNNNLERHKSCHTKRNSNVCEFCSKTFVSENRLKIHKENHCKKAGDTAKFYRSDVAVWRCEQCKQVFATHESGNKHIKQCTTVEPLTSVVKADDKQINENNIINIKSIFEENNFDSNFEKAITNQPGFYKESTITLEKIITEMLYQCEFCNRTYAEKMAVLNHQKTHTTEKNYECIFCDQHFNSYCQATVHWQSKCNNESNLFYLPKMIYCEHCDRGFKSHEILYNHKNKKKHFSPKIHNKQKEKNEEVKSENEKAIAKLIENMITKLDQNVQLSAIDNEIDPKENDENSLLVPVGSVKLENDEENNPENGKKKRGRKRKWQKTEMKNKIINEEGCQYQCERCAAVFETIVTLDVHKDTTHASTYKCEQCGQIVHSAKALMIHCRAHQCLKPYVCDQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCQKCFLTGSVYYQHRLIHTNDRRYGCEFCNKRFFRADALNNHRRIHTDERPYPCPVCGREFRQKGDRNKHVRTQHSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00029613;
90% Identity: iTF_01105048;
80% Identity: -