Aful050417.1
Basic Information
- Insect
- Agonum fuliginosum
- Gene Symbol
- topi
- Assembly
- GCA_947534325.1
- Location
- OX384032.1:23932514-23934909[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00029 0.041 15.8 1.8 2 21 134 153 133 154 0.94 2 13 9e-05 0.013 17.4 3.4 1 21 179 199 179 201 0.94 3 13 0.0033 0.46 12.5 0.8 3 23 209 229 208 229 0.95 4 13 0.14 20 7.3 0.5 2 21 248 267 247 268 0.91 5 13 0.00097 0.14 14.1 0.9 1 23 335 357 335 357 0.99 6 13 0.46 64 5.7 3.9 2 22 400 420 399 423 0.86 7 13 1.3 1.8e+02 4.3 0.0 1 23 528 551 528 551 0.91 8 13 0.11 16 7.6 1.0 1 23 555 577 555 577 0.93 9 13 8.4e-07 0.00012 23.8 2.4 1 23 583 605 583 605 0.98 10 13 0.029 4.1 9.5 0.2 1 23 611 636 611 636 0.96 11 13 0.27 38 6.5 3.3 1 23 642 664 642 664 0.86 12 13 2.7e-05 0.0038 19.0 0.5 3 23 672 692 670 692 0.98 13 13 2.4e-06 0.00033 22.4 0.3 1 23 698 721 698 721 0.98
Sequence Information
- Coding Sequence
- ATGAGCTATCAAGACAGTATATTGTTAAAATTACATCACGTAGTAGATACTGGTAATGGTATGTTAAATGCTCCTGTACAAATTGAAATTGATTCTTCAGACAAGGTAGTTGCAAGCACATTACTTACTGAACCACTCGTTAATTTTGAGTCCCAATTCGTAAACTGGAATTCTTGTGTTGATGATAAATGTAATTTAAATTATCGCCGTTTTGTGGAAGGTCCAATCCCCTCAGTAACATTAATTAAAATTGGAAGTGTAGATGATTTAAATCCAATGAATTATATAACACAGCTTAATTCGTTCACCAATAATTGTCTTGATGATACTAATTATATTTTCTCGGAGACAAAAAAAACGCAACAAAAACGTTTAAATTTACCTGACACAAGTACAATATCATGCCAAAATTGCGATACTTCTTTTCCAACAAAATATCAGTATCAGCGTCATCAGTGCGAATTTAATGCTGAAAAAGTTGTTTTGAAACCAGAGATAGCAGGAAAAGATGTAGATAAAGCCACTAGATTGAGATTTGAATGTGATGTTTGCAAAAAATCGTTTGTCAGTAATAATAATTTGGAACGACATAAAAATTGTCATAAAAATAGAAATAGTAATATTTGTGAATACTGTAGCAAGACATTCGTTAGTGAAAATCGATTAAAAATTCATAAAGAAAATCATTGCAAAAAAGCAGGCGATACAACAAAATTTTATCGGAGTGACGTAGCTGTTTGGCGATGCGAACAATGTAAACAAGTATTTGCTACTCATGAAAGCGGAAATAAACATATAAAACAATGTACAACAGTTGAACCATCAACATCAACTATTGTTAAATCTGATATAAAACCTCTGACGGAAAACAACATATTGAACATAAAAAGTATTTTTGAAAAAAATAATTTCGATCCTAATTTTGAAAATGCAATAACGAATCAACCTGGTTTCTATAAAGAAACTACTATTACACTGGAAAAAATTATTACTGAGATGTTATATCAATGTGAATTTTGCAATCGTACTTATGCCGAAAAAATGGCAGTATTAAATCATCAAAAAACTCACTCAACTGAAAAAAATTACGAATGTATTTTTTGCGATCAATATTTTAATAGTTACTGTCAAGCTACAGTTCATTGGCAAAGTAAATGTAATAACGAGTCAAATTTATTTTATTTGCCCAAAATGATTTATTGCGAGCATTGTGATAGAGGTTTTAAGTCGCATGAAATTCTATACAATCACAAAAATAAGAAAAAACATTTTACTCCAAAAATACATAATAAAATAGAAGAAAAAAGTGATGGAGATGTAAAGTCTGAAAATGAAAAGCAAATTGCTAAGTTAATAGAAAATATGATCGCTAAACTAGATCAGAATGTTAATTTATCATTAACTGAAAATGAAGACCAAAAGGAAAATGAGGAAAATAATTTATTGGTACCTATTGGAAGTATCAAAGTTGAAAATTATGAAGAAAATAACCCGGAAAATGGTAAAAAGAAACGCGGACGTAAGCGAAAATGGCAAAAAACTGAGGTAAAGAATAGAGTTGTTGTTGAAGAAGGCTGCCAGTATCAATGTGAACGATGTGCTGCTGTTTTTGAAACAATTATTACTTTAGATATTCATAAAGATTCAGCACATGCCAGTACTTACAGGTGCGAACAATGTGGGCAGATAGTTCATAGCGCAAAAGCTTTAATGATTCATTGCCGTGCTCATCAAAGCCTTAAACCCTATGTATGTGACCAATGTGGTCGCAGCTATTCCCAAACCTCTCATCTATGGCAGCATATGAGATTCCATCAAGGAATCAAACCATTCGCTTGCCCACATGAAGGCTGTGAAGCTCGTTATACAATTCGCCCGGATTTGAAAGACCACATTCGTAAAGTTCATACTCGAGAACGCCCTTTTAAATGTTCTGTTTGTAATAAATGTTTCTTAACTGGATCAGTTTATTATCAACACCGTTTAATTCACACAAATGATCGTAGATATGGGTGTGAGATTTGCAGTAAACGATTTTTCCGAGCTGATGCTTTAAACAATCATCGAAGAATTCATACAGATGAGCGTCCTTATCCATGTCCAGTTTGTGGAAGAGAATTTAGACAGAAAGGAGATAGAAATAAGCATGTTCGCACTCAACATTCCATGTAA
- Protein Sequence
- MSYQDSILLKLHHVVDTGNGMLNAPVQIEIDSSDKVVASTLLTEPLVNFESQFVNWNSCVDDKCNLNYRRFVEGPIPSVTLIKIGSVDDLNPMNYITQLNSFTNNCLDDTNYIFSETKKTQQKRLNLPDTSTISCQNCDTSFPTKYQYQRHQCEFNAEKVVLKPEIAGKDVDKATRLRFECDVCKKSFVSNNNLERHKNCHKNRNSNICEYCSKTFVSENRLKIHKENHCKKAGDTTKFYRSDVAVWRCEQCKQVFATHESGNKHIKQCTTVEPSTSTIVKSDIKPLTENNILNIKSIFEKNNFDPNFENAITNQPGFYKETTITLEKIITEMLYQCEFCNRTYAEKMAVLNHQKTHSTEKNYECIFCDQYFNSYCQATVHWQSKCNNESNLFYLPKMIYCEHCDRGFKSHEILYNHKNKKKHFTPKIHNKIEEKSDGDVKSENEKQIAKLIENMIAKLDQNVNLSLTENEDQKENEENNLLVPIGSIKVENYEENNPENGKKKRGRKRKWQKTEVKNRVVVEEGCQYQCERCAAVFETIITLDIHKDSAHASTYRCEQCGQIVHSAKALMIHCRAHQSLKPYVCDQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCNKCFLTGSVYYQHRLIHTNDRRYGCEICSKRFFRADALNNHRRIHTDERPYPCPVCGREFRQKGDRNKHVRTQHSM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01226113; iTF_01275663; iTF_00767543; iTF_01105048; iTF_00769114;
- 90% Identity
- -
- 80% Identity
- -