Basic Information

Insect: Ophion ventricosus
Gene Symbol: znf423
Assembly: GCA_963932345.1
Location: OZ010711.1:27772204-27788869[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 8.9e-06 0.0008 19.9 1.5 1 23 81 103 81 103 0.98

2 19 0.22 19 6.1 4.9 1 23 109 131 109 131 0.98

3 19 1.2e-06 0.0001 22.7 4.1 1 23 137 159 137 159 0.99

4 19 0.00024 0.021 15.4 0.2 1 23 165 187 165 187 0.99

5 19 0.00023 0.02 15.5 0.4 1 23 349 372 349 372 0.94

6 19 0.093 8.3 7.3 0.1 2 23 383 405 382 405 0.89

7 19 0.22 20 6.1 0.1 3 23 475 495 474 495 0.97

8 19 0.00083 0.074 13.7 0.1 3 23 512 532 511 532 0.97

9 19 0.00026 0.024 15.3 0.6 1 23 541 564 541 564 0.94

10 19 2.5 2.2e+02 2.8 0.1 1 23 569 592 569 592 0.91

11 19 0.58 52 4.8 2.4 2 23 667 688 666 688 0.96

12 19 0.0012 0.11 13.2 0.0 1 23 693 716 693 716 0.95

13 19 0.54 48 4.9 0.1 2 23 787 810 786 810 0.88

14 19 4.8e-05 0.0043 17.6 1.0 2 23 826 848 825 848 0.96

15 19 0.066 5.9 7.7 1.5 1 23 857 880 857 880 0.93

16 19 0.0057 0.51 11.1 0.2 2 23 1095 1117 1094 1117 0.96

17 19 0.1 8.9 7.2 0.4 1 23 1125 1148 1125 1148 0.96

18 19 0.0083 0.74 10.6 0.2 2 23 1191 1213 1190 1213 0.94

19 19 0.045 4 8.3 1.1 1 23 1220 1243 1220 1243 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	8.9e-06	0.0008	19.9	1.5	1	23	81	103	81	103	0.98
2	19	0.22	19	6.1	4.9	1	23	109	131	109	131	0.98
3	19	1.2e-06	0.0001	22.7	4.1	1	23	137	159	137	159	0.99
4	19	0.00024	0.021	15.4	0.2	1	23	165	187	165	187	0.99
5	19	0.00023	0.02	15.5	0.4	1	23	349	372	349	372	0.94
6	19	0.093	8.3	7.3	0.1	2	23	383	405	382	405	0.89
7	19	0.22	20	6.1	0.1	3	23	475	495	474	495	0.97
8	19	0.00083	0.074	13.7	0.1	3	23	512	532	511	532	0.97
9	19	0.00026	0.024	15.3	0.6	1	23	541	564	541	564	0.94
10	19	2.5	2.2e+02	2.8	0.1	1	23	569	592	569	592	0.91
11	19	0.58	52	4.8	2.4	2	23	667	688	666	688	0.96
12	19	0.0012	0.11	13.2	0.0	1	23	693	716	693	716	0.95
13	19	0.54	48	4.9	0.1	2	23	787	810	786	810	0.88
14	19	4.8e-05	0.0043	17.6	1.0	2	23	826	848	825	848	0.96
15	19	0.066	5.9	7.7	1.5	1	23	857	880	857	880	0.93
16	19	0.0057	0.51	11.1	0.2	2	23	1095	1117	1094	1117	0.96
17	19	0.1	8.9	7.2	0.4	1	23	1125	1148	1125	1148	0.96
18	19	0.0083	0.74	10.6	0.2	2	23	1191	1213	1190	1213	0.94
19	19	0.045	4	8.3	1.1	1	23	1220	1243	1220	1243	0.95

Sequence Information

Coding Sequence: ATGAGGATAGGAGAAGAGGAGCACGCGCGCGAGGGAATGAACGAGGGTGGAAGAAGCATCACGGACGCTCTCGGGACCGGAAGTTCGTCATGGCACAGCGAGGATGGCGGTGCGAATTCGCGACGGGGCGGAGAAACCCCCTCGTCCTGCGCGACTCCAACATCGGCGAGTTTCCCCTCGGAACCGGAAGTCGATACCGAAGTCGGCATCAACGCCGATGGTAACAATTCCGTTGCCCCTTATCCCTGCCAATTCTGCGACAGGACTTTCCCGCGACTCAGCTACTTGAAGAAACACGAGCAGaGTCACGGCGATCAGATGCCGTACCGTTGCAGCTGGTGTTCGCGTCTCTTCAAGCACAAGCGAAGCAGGGATCGTCACGTCAAGCTGCACACCGGCGACCGAAGGTATCGGTGCTCTCACTGCGAAGCCGCGTTCTCCAGAAGTGATCACCTGAAGATTCACATGAAGACACACGACAATCAGAAGCCTTATCAGTGCACCGCTTGTTCGCGcggctacaacacagcggcagccCTAACCTCGCACATGCAATCCCACAAGAAGCACGCGAGTCCAAATCAGAACGCAAAGATGGCAGATATTGATTACGGGCGACGGAGCGTCTCGTCGCACAGTACCTCGTCACCGCCTATCCAAAATTCTCCGTCTCCGAGCTTGAATCTAACCGCAAATCTGAAGAATTCATTGAAATCACAACAATCGATTTACAGCAGTGGGAACAACGGTCCAAAAACTTCCGCCATGTTGAATTCACCGTTGAAGTTGGCCTGCATGTATTGCACGAAGGACTCGTTCACGAGTATGCACCAATTGCAGATGCACGTACACGCGATGCATCAGGCGATATTGAACGGGGCGACTTTGAACGTGGAGTCACCGGGACAGACGAATAAGCCGGAAGCGATCAGCTCAAAAGGCCACGATGCACCGTCCGTTGTGGAACGAAACAACGAACCCGAGAGAACGTATCGTCGCGAAAAGTCCGGAGAATTGGACCGGATCAGCACTTTGGAGAACGCATTCTCTTGCAGCCAGTGCACCATGAAGTTTTCCAGTCTGAGCGAGCTACGCGATCATCTGTTGGCAATTCATCGAGGAGATGGGTTCGGCTCGAGCCTGATGATGTGTCCACTGTGCGGTATTACTTGCGCCTCTGCTGCCTCTTACGCGGAACACTATGTCCTCCAACACTGCGAGAATCGTCAAGTGGCTGGCAAGGATTCGCACCATCGAGACTGGGACGTTTCGAGGATGAACGGTAGTCGGGAGAGCAGCCGAGGTGCTTCGGATGATCACGGCACAACGAGTAGATCTGATCTTGGAACATCGGAGCCGGCCGATTTGACGAAGAAGCAAGCTAGAGCCGGGGATACCGGTTACACAACTGGGACACTATTGTGCGGTCAATGCGGTGCCGCGTTGAAGGACTTTGAGTCGTTTCGCGAACATCTGGCTCGTCATCTTCAAGCCGATCAGCAGCAGAACATTGAACCTTTACCGAGGAATCCATGCCCGAAGTGCGGCACGAGTTTTCCCGAACGTGAAGACATGTTGGCTCATCTCACCAAACACTATCTTGGCCAAGTTACCAAGGAGTACACTTGTGGCGCTTGCAAAAAGTCTTATCCTCATCCGGATCTTCTGCAACGACATCTCCTCGACACCCACGCCCATCATCTCTACCGTTGCGCCGTATGCCGCGACACCTTCGACTCCAGGGTCGCCATTCAGGTTCATTTCGCGGTCAAACACAGCCAGGAGTCTCAGGTATATCGTTGCAACGTATGCAACGCCTCGGGCAATGAGAATTCCCCGGGGAATTCGCCCGGCGAGGTGAGAAATTGCTTCCGCAGCGAGGCCGAAATGGCCAATCACGTTAGATCGATTCACGCACCAACCACCAACATCGTCGACGAGGCACCTCTGCGAAGAAGTCCCGCGGTCACGCCAGCCAGCAATGCCACTAACACCAGCAGATGCGTGTTTTGCGGTCACAGCTGCAACACGGATTTGGAGCTACAGCTTCATCTGGCGAGCCATTCCGCCAATCTTTATCGATGCCCAATATGCAGAGAAGGATTCCCAGTTGAGTTTCTCTTGGAGAGGCACATAGCTCAGGCCCATCGAGCCAGCAGTGATCGGAACGACGGGAGGGAGAATGGAAGGTCCTACAGGACTTCGAGGTCGCAGGACGAAACGGCAAGGTCACAAAAGCGCGGACGATCGCCAGCCTCGAGTAACAACAATTCGCTGAATCAACGTGACAACAATAGCAAACGACCAAATTACGGGGGTGTTAGCAACGGAACCGGCACGAGCAGCTCGCGCGTGCAGCAATGCGAGCTCTGCGAGAGAGCGGAATTTACAACGGAAGCGGAACTTCAGGCGCACAAAAAGCTCGTTCATACACCGATTAAAGTACAGGCTAAGTCTCTACCGTTGCTAAGCATGACCTGCGCTTACTGCGGCGAGGTTTGTCGTTCGCGAAGCGATCTTGAGTCCCACACGAGAATTCAACACGCTTTGAACGAGCCCGGTGGACGTCACAAGTGTAACATTTGCGACGAGGTCTGTCCATCAGGCAGGACATTGGCCGAGCACAAGCTCCAGACTCATTGCAAGATTCAAGTTAGCGACACTTGTATCGTGTGTCGTGGTACACTCTCGAGCGAGGCCCAATTCATCGAGCATGTCCAGCGACACAGCTTGGAAAGTGGCGAGTCTCAGCAACGTTGTTCGGATAGCACGCTTCCTCTTTTGCCAGCGGCTTGCGTCGTTTGTCGTCAGACGCTGATGAGCGATCTTGAGTGTCGTTTACATGCGGCTCACCATTTGAGAAGTTCCAATTTATCTGGTGTGACGAATTCCAGTCCGAGCCCGAATCACCACAAGCAACAACAATTCTTTCAACAGACAAACCTGAGCTGTTGCCTTTGCCTGCGAGACTTCAGCGTCGATGATTTCGTTAGCTTGCCATCCAATAATAGTGTGAGCGCGGGTGGTGGTCCATCTTTGAGGGTCTGCAGACCTTGCTATGTCAGGCACTCACAAGGCCTGCCCATACTAAGTTCACCCTACGAACACGTGAAACAGTCCAAGAGCGAGCGAAACACTTGGTTGAACGGTAAGGATCGCGCCAACAAGGACAACTCGACGGACCGATGGGATCAGAATGAGAGATCGTATGGCGTTGACGAACGCGACAGGAGCCAAAGCGTGAACGCGAAGAGTGAGATCAACGGATCGGATGGTGGCGACAGGTGCGACGAGTGCGGTATCAAATTTGAGAATACTGACGAGGCTGAAACTCATAGGAACAAAGAACACGGCAAAGGACCAAGGAACACTTACACCTGCATACAATGTCAGATGTCTTTTCCGTCGGAGGAGAAAATTCGTCAGCACGTGAGAAAGGTTCACTTGGAATCTTCGAGCAAGACCTTGAGCGAGGCGTTTCGCTGTCACCTTTGCATATTCGAAGCCAACAGCCCGCTTCAGCTCCAGGGACACTTGATAGAGCACACTTTCGCTGGTTGCGCAGGCCTTACGTGCTACATCTGCCAGGGTCTCTTCACAACGCCCCAGGCACTTCAAAATCACATGCTGCAGCAACACGGACTTGGCGCTCGTCCCTACGACTGCAGCAACTGTGGCCTCAAGTTTTTCTTCCGTATCGAGCTGGACCATCACGAGATGATGGTACATCGCGGTAACGGCACCTCTTCACCCAACGTGGTGGATGCTGGTCGAGAAGTCGCACCGGAAAACTCCCGATTGGTTGAAGCTTCAGGCATCAAACAGCTGGACGAGGATGATCGCGAGCTTCCTGGATCGAACGCTATCACGGTGAAGGAGGAAATCGTCAGTAGCCCCGGCGACAAGGAATTCCATTTGGAAGACGGTGTTCCAGAAAATGGCGTTACCGAAACGAAAGAAGGAGAGCCACGTTTTCTCGAAGCGAAGACGGAAACTTTTGGAATAATTCGCAGCGAAGACAATATCCAATCTTGA
Protein Sequence: MRIGEEEHAREGMNEGGRSITDALGTGSSSWHSEDGGANSRRGGETPSSCATPTSASFPSEPEVDTEVGINADGNNSVAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDNQKPYQCTACSRGYNTAAALTSHMQSHKKHASPNQNAKMADIDYGRRSVSSHSTSSPPIQNSPSPSLNLTANLKNSLKSQQSIYSSGNNGPKTSAMLNSPLKLACMYCTKDSFTSMHQLQMHVHAMHQAILNGATLNVESPGQTNKPEAISSKGHDAPSVVERNNEPERTYRREKSGELDRISTLENAFSCSQCTMKFSSLSELRDHLLAIHRGDGFGSSLMMCPLCGITCASAASYAEHYVLQHCENRQVAGKDSHHRDWDVSRMNGSRESSRGASDDHGTTSRSDLGTSEPADLTKKQARAGDTGYTTGTLLCGQCGAALKDFESFREHLARHLQADQQQNIEPLPRNPCPKCGTSFPEREDMLAHLTKHYLGQVTKEYTCGACKKSYPHPDLLQRHLLDTHAHHLYRCAVCRDTFDSRVAIQVHFAVKHSQESQVYRCNVCNASGNENSPGNSPGEVRNCFRSEAEMANHVRSIHAPTTNIVDEAPLRRSPAVTPASNATNTSRCVFCGHSCNTDLELQLHLASHSANLYRCPICREGFPVEFLLERHIAQAHRASSDRNDGRENGRSYRTSRSQDETARSQKRGRSPASSNNNSLNQRDNNSKRPNYGGVSNGTGTSSSRVQQCELCERAEFTTEAELQAHKKLVHTPIKVQAKSLPLLSMTCAYCGEVCRSRSDLESHTRIQHALNEPGGRHKCNICDEVCPSGRTLAEHKLQTHCKIQVSDTCIVCRGTLSSEAQFIEHVQRHSLESGESQQRCSDSTLPLLPAACVVCRQTLMSDLECRLHAAHHLRSSNLSGVTNSSPSPNHHKQQQFFQQTNLSCCLCLRDFSVDDFVSLPSNNSVSAGGGPSLRVCRPCYVRHSQGLPILSSPYEHVKQSKSERNTWLNGKDRANKDNSTDRWDQNERSYGVDERDRSQSVNAKSEINGSDGGDRCDECGIKFENTDEAETHRNKEHGKGPRNTYTCIQCQMSFPSEEKIRQHVRKVHLESSSKTLSEAFRCHLCIFEANSPLQLQGHLIEHTFAGCAGLTCYICQGLFTTPQALQNHMLQQHGLGARPYDCSNCGLKFFFRIELDHHEMMVHRGNGTSSPNVVDAGREVAPENSRLVEASGIKQLDEDDRELPGSNAITVKEEIVSSPGDKEFHLEDGVPENGVTETKEGEPRFLEAKTETFGIIRSEDNIQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01101554;
90% Identity: iTF_01103016; iTF_01100809; iTF_01101554; iTF_01102263;
80% Identity: -