Basic Information

Insect: Ophion costatus
Gene Symbol: znf423
Assembly: GCA_951751655.1
Location: OX632358.1:36940971-36972229[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 9.1e-06 0.001 19.9 1.5 1 23 97 119 97 119 0.98

2 20 0.22 25 6.1 4.9 1 23 125 147 125 147 0.98

3 20 1.2e-06 0.00014 22.7 4.1 1 23 153 175 153 175 0.99

4 20 0.00024 0.028 15.4 0.2 1 23 181 203 181 203 0.99

5 20 0.00041 0.048 14.7 0.3 1 23 365 388 365 388 0.94

6 20 0.28 32 5.8 0.0 2 23 399 421 398 421 0.88

7 20 0.22 26 6.1 0.1 3 23 491 511 490 511 0.97

8 20 0.092 11 7.3 0.0 3 23 528 548 527 548 0.96

9 20 0.00027 0.031 15.3 0.6 1 23 557 580 557 580 0.94

10 20 2.5 2.9e+02 2.8 0.1 1 23 585 608 585 608 0.91

11 20 8.4 9.6e+02 1.1 0.1 9 23 639 654 638 654 0.94

12 20 3.1 3.5e+02 2.5 4.8 2 23 683 704 682 704 0.96

13 20 0.0012 0.14 13.2 0.0 1 23 709 732 709 732 0.95

14 20 0.55 63 4.9 0.1 2 23 803 826 802 826 0.88

15 20 4.5e-05 0.0052 17.7 1.0 2 23 842 864 841 864 0.96

16 20 0.039 4.4 8.5 0.8 1 23 873 896 873 896 0.93

17 20 0.0055 0.63 11.2 0.0 2 23 1110 1132 1109 1132 0.95

18 20 0.1 12 7.2 0.4 1 23 1140 1163 1140 1163 0.96

19 20 0.0085 0.97 10.6 0.2 2 23 1206 1228 1205 1228 0.94

20 20 0.008 0.92 10.6 1.1 1 23 1235 1258 1235 1258 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	9.1e-06	0.001	19.9	1.5	1	23	97	119	97	119	0.98
2	20	0.22	25	6.1	4.9	1	23	125	147	125	147	0.98
3	20	1.2e-06	0.00014	22.7	4.1	1	23	153	175	153	175	0.99
4	20	0.00024	0.028	15.4	0.2	1	23	181	203	181	203	0.99
5	20	0.00041	0.048	14.7	0.3	1	23	365	388	365	388	0.94
6	20	0.28	32	5.8	0.0	2	23	399	421	398	421	0.88
7	20	0.22	26	6.1	0.1	3	23	491	511	490	511	0.97
8	20	0.092	11	7.3	0.0	3	23	528	548	527	548	0.96
9	20	0.00027	0.031	15.3	0.6	1	23	557	580	557	580	0.94
10	20	2.5	2.9e+02	2.8	0.1	1	23	585	608	585	608	0.91
11	20	8.4	9.6e+02	1.1	0.1	9	23	639	654	638	654	0.94
12	20	3.1	3.5e+02	2.5	4.8	2	23	683	704	682	704	0.96
13	20	0.0012	0.14	13.2	0.0	1	23	709	732	709	732	0.95
14	20	0.55	63	4.9	0.1	2	23	803	826	802	826	0.88
15	20	4.5e-05	0.0052	17.7	1.0	2	23	842	864	841	864	0.96
16	20	0.039	4.4	8.5	0.8	1	23	873	896	873	896	0.93
17	20	0.0055	0.63	11.2	0.0	2	23	1110	1132	1109	1132	0.95
18	20	0.1	12	7.2	0.4	1	23	1140	1163	1140	1163	0.96
19	20	0.0085	0.97	10.6	0.2	2	23	1206	1228	1205	1228	0.94
20	20	0.008	0.92	10.6	1.1	1	23	1235	1258	1235	1258	0.96

Sequence Information

Coding Sequence: ATGCTGTTCAAAGGCAACAGTTCGCGGCTGGAATTGCTGATCGGAAAGATCCAGGCGCACAAGGAATCACCGTCGCCGCCACGACCTGACAAGCGCGGCACCAGGTCCAAAGACGCTCTCGGGACCGGAAGTTCCTCATGGCACAGCGAGGATGGCGGTGCAAACTCGCGACGGGGCGGAGAAACTCCCTCGTCCTGCGCGACTCCAACGTCGGCCAGTTTCCCCTCGGAACCGGAAGCCGACACCGAAGTCGGCATCAACGCCGATGGCAACAATCCCGTTGCCCCTTATCCCTGCCAATTCTGCGACAGGACCTTCCCGCGACTCAGCTACTTGAAAAAACACGAGCAGAGTCACGGCGATCAAATGCCGTACCGTTGCAGCTGGTGTTCGCGTCTGTTCAAGCACAAGCGAAGCAGAGATCGTCACGTCAAGTTGCACACCGGCGACCGAAGGTATCGGTGCTCCCATTGCGAGGCGGCGTTCTCCAGAAGTGACCACCTGAAGATTCACATGAAGACACACGACAATCAGAAGCCTTATCAGTGCACCGCTTGTTCGCGCGGCTACAACACAGCGGCTGCCCTAACCTCGCACATGCAATCGCACAAGAAGCACGCGAGTCCGAATCAAAACGCGAAGATAGCGGACATCGATTACGGACGACGAAGCGTTTCGTCGCACAGTACCTCGTCACCGCCTGTCCAAAATTCGCCGTCTCCGAGCTTGAGTCTCGGCGCAAATCTGAAGAATTCCCTGAAGTCGCATCAATCGATTTACAGCAGCGGGAACAACGGTCCGAAAACGTCGGCCATGCTGAATTCGCCGTTGAAGTTGGCCTGCATGTATTGCACGAAGGACTCGTTCACGAGTATGCACCAATTGCAGATGCACGTACACGCGATGCATCAGGCGATACTGAACGGGGCGACCTTGAACGTGGAGTGCCCGGGGCAGGCGAATAAGCAGGAAGCGATCAGCTCCATGGGCCGCGACGGACCCACCGTTGCGGAAAGAAACAACGAATCCGAGAGAACGTATCGTCGCGATAAGTCCGTGGAACTGGACCGGCTGAACACTACGGACGACGCATTCTCCTGCGGCCAGTGCACCATGAAGTTTTCCAGTCTGAGCGAGCTGCGGGATCATCTGTTGGCGATTCATCGAGGCGACGGATTCGGCTCGAGTCTGATGATGTGTCCGCTTTGCGGTATTCCTTGCGCCTCTGCTGCCTCCTACGCGGAACACTACGTCCTTCAGCACTGCGAGAATCGCCGGGTGGCCGGCAAGGATTCGCACCATCGAGACTGGGACGTTTCGCGGATGAACGGTAGCCGCGAGAGCAGTCGAGCTGCCTCGGAGGATCAGGGCACGACGAGCAGATCTGATAATGGAACGTCGGAGCCTGCCGACTTGACGAAGAAGCAGGCGAGACCCGGTGATACCGGTTACACAAGCGGGACACTTCTGTGCGGTCAGTGCGGCGCTGCGTTGAAGGACTTCGAGTCGTTTCGCGAACATCTGGCCCGTCATCTTCAAGCCGATCAGCAGCAGAGCAGCGAACCGTCGCCGAGGAATCCGTGCCCCAAGTGCGCCGCGAGTTTTCCCGAACGCGAAGACATGCTGGCACATCTCACCAAACACTATCTTGGCCAAGTCACCAAGGAGTACACTTGCGGCGCTTGCAAGAAGTCGTATCCCCATCCGGATCTTTTGCAACGTCATCTACTCGACACCCACGCCCAACATCTCTACCGGTGCGCCGTCTGCCGTGACACCTTCGACTCAAGAGTCGCCATTCAGGTCCACTTCGCGGTCAAACACAGCCAGGAGTCTCAGATCTATCGTTGCAACGCGTGCAACGCCTCCGGCAACGAGAATTCCCCCGGGAATTCGCCGGGCGAGGTTAGAAATTGCTTCCGCACCGAGGCCGAAATGGCCAATCACGTTAGATCCATTCACGCACCATCAGCGAACATCAGCGACGAGGCACCTCCGCGAAGAAGTCCCGCGGTCACGCCAGCCGGTAACGCCGTTAATACCAGCAGATGCGTCTTTTGCGGTCACTGCTGCAACACGGATTTGGAGCTGCAGCTTCATCTGGCGAGCCACTCCGCCAATCTCTATCGATGCCCGATCTGCAGGGAAGGATTTCCCGTTGAGTTCCTCTTGGAGAGGCACATAGCTCAGGCCCATCGAGCCAGCAGTGATCGGAACGACGGAAGGGAAAATGGAAGGTCCTACAGGGCGTCAAGGTCGCAGGACGAAACGGCGAGGTCACAAAAGCGCGGACGATCGCCAGCCTCGAGTAACAACAATTCGCTGAATCAGCGGGACAACAATAACAAACGACCGAACTACGGGGCGGTCAGCAACGGGACCGGCACAAGCAGCTCTCTCGTGCAACAATGCGAGCTCTGCGAAAGAGCCGAGTTCACAACAGAAGCGGAACTTCAGGCGCACAAAAAGCTCGTCCACACACCGATCAAGGTACAGGCTAAGTCTCTACCGTTGCTCAGTATGACCTGCGCTTACTGCGGCGAGGTTTGCCGTTCGCGAAGCGATCTGGAGTCCCACACGAGAGTCCAACACGCCTCGAACGAGCCCGGTGGACGTCACAAGTGTAACATTTGCGACGAGGTCTGTCCATCGGGCGGGACATTGGCCGAGCACAAGCTCCAGACTCATTGCAAGATTCAAGTGAGCGACACTTGTATCGTGTGTCGCGGCACGCTGTCGAGCGAGGCCCAATTCGTGGAGCATGTCCAGCGACACAGCTTGGAGAGTGGCGAGTCCCATCAACGTTGTACGGACAGCACGCTTCCTCTTTTGCCTGCGGCTTGCGTCGTTTGTCGTCAGACGCTCATAAGCGATCTTGAGTGTCGTTTGCACGCGTCTCACCATTTGAGGCTTTCCAATGTACCTGGAGTGACGATTGCCAGTCCAAGCCCGAATCACCacaagcaacaacaacaactctTCCAACAGAGCAATCTGAGCTGCTGTCTTTGTCTGCGAGACTTCAGCGTCGATGACTTCGTAAGCTTGCCGTCCAATAATCCCGTGGGCGCCGGTGGTGGGCCACCATTGAGGGTCTGCAGACCTTGCTACGTCAGGCACTCCCAAGGCCTGCCCATACTCAGTTCACCCTACGAACACGTGAGACAGTCCAAGAGCGAACGAAACACTTGGTTGAACGGTAAGGATCGCCCCAACAGGGACAACTCGAGGGATCAATGGGATCAGAACGAGAGATCGTACGGCGTTGACGAGCGCGACAGGAGCCAAAGCGCGAAGACCGGGATCAACGGATCGGATGGTGGCGACAGGTGCGACGAGTGCGGTATCAAGTTTGAAAGTCCTGGCGAGGCTGAAGCTCACAGGATCAAGGAACATGGCAAAGGAACAAGGAACACTTACACCTGCATacaatgtcagATGTCTTTCCCATCGGAGGAGAAAATTCGTCAGCACGTGAGGAAGGTCCATTTGGGATCCTCGAGCACGTCCTTGAGCGAGGCGTTGCGCTGTCACCTTTGCATATTCGAAGCCAACAGTCCTCTCCAGCTCCAGGGACACTTGATAGAGCACACTTTCGCCGGTTGCGCTGGCCTCACCTGCTACATCTGCCAGGGTCTCTTCACGACGCCCCAGGCACTTCAGAATCACATGCTGCAGCAACACGGACTCGGCGCCCGTCCCTACGACTGCAGCAACTGCGGCCTCAAGTTTTTCTTCCGCATCGAGCTTGAACATCACGAGATGATGGTGCATCGCGGTAACGACACCTCGtcacccaaaatggcggacgccGCTCGAGACGTCGCGCCGGAAAATCGCGAAATGGCCGAAGATTCAGGCATCAAACAGCTGGACGAGGATAATCGCGAGCTGCCTGCATCGAACGCTGTCACCGTGAAGGAAGAAATCGTCGGCAGTCCCAGCGACAAGGACTTCCAGCTGGACGACCATGTTGGACAAAATGGCGATTCGGAAACGAAAGAAGAGGAGCCACATTTTCTCGAAGCTAAGACGGAATCTTTTGGGATAGCGCACAGCGAAGACAATACACAATCTTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKESPSPPRPDKRGTRSKDALGTGSSSWHSEDGGANSRRGGETPSSCATPTSASFPSEPEADTEVGINADGNNPVAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDNQKPYQCTACSRGYNTAAALTSHMQSHKKHASPNQNAKIADIDYGRRSVSSHSTSSPPVQNSPSPSLSLGANLKNSLKSHQSIYSSGNNGPKTSAMLNSPLKLACMYCTKDSFTSMHQLQMHVHAMHQAILNGATLNVECPGQANKQEAISSMGRDGPTVAERNNESERTYRRDKSVELDRLNTTDDAFSCGQCTMKFSSLSELRDHLLAIHRGDGFGSSLMMCPLCGIPCASAASYAEHYVLQHCENRRVAGKDSHHRDWDVSRMNGSRESSRAASEDQGTTSRSDNGTSEPADLTKKQARPGDTGYTSGTLLCGQCGAALKDFESFREHLARHLQADQQQSSEPSPRNPCPKCAASFPEREDMLAHLTKHYLGQVTKEYTCGACKKSYPHPDLLQRHLLDTHAQHLYRCAVCRDTFDSRVAIQVHFAVKHSQESQIYRCNACNASGNENSPGNSPGEVRNCFRTEAEMANHVRSIHAPSANISDEAPPRRSPAVTPAGNAVNTSRCVFCGHCCNTDLELQLHLASHSANLYRCPICREGFPVEFLLERHIAQAHRASSDRNDGRENGRSYRASRSQDETARSQKRGRSPASSNNNSLNQRDNNNKRPNYGAVSNGTGTSSSLVQQCELCERAEFTTEAELQAHKKLVHTPIKVQAKSLPLLSMTCAYCGEVCRSRSDLESHTRVQHASNEPGGRHKCNICDEVCPSGGTLAEHKLQTHCKIQVSDTCIVCRGTLSSEAQFVEHVQRHSLESGESHQRCTDSTLPLLPAACVVCRQTLISDLECRLHASHHLRLSNVPGVTIASPSPNHHKQQQQLFQQSNLSCCLCLRDFSVDDFVSLPSNNPVGAGGGPPLRVCRPCYVRHSQGLPILSSPYEHVRQSKSERNTWLNGKDRPNRDNSRDQWDQNERSYGVDERDRSQSAKTGINGSDGGDRCDECGIKFESPGEAEAHRIKEHGKGTRNTYTCIQCQMSFPSEEKIRQHVRKVHLGSSSTSLSEALRCHLCIFEANSPLQLQGHLIEHTFAGCAGLTCYICQGLFTTPQALQNHMLQQHGLGARPYDCSNCGLKFFFRIELEHHEMMVHRGNDTSSPKMADAARDVAPENREMAEDSGIKQLDEDNRELPASNAVTVKEEIVGSPSDKDFQLDDHVGQNGDSETKEEEPHFLEAKTESFGIAHSEDNTQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01101554;
90% Identity: iTF_01103749;
80% Identity: -