Basic Information

Insect: Ophion obscuratus
Gene Symbol: znf423
Assembly: GCA_964007375.1
Location: OZ023315.1:17741736-17782133[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 9.9e-06 0.0016 19.9 1.5 1 23 97 119 97 119 0.98

2 22 0.24 38 6.1 4.9 1 23 125 147 125 147 0.98

3 22 1.3e-06 0.00021 22.7 4.1 1 23 153 175 153 175 0.99

4 22 0.00026 0.042 15.4 0.2 1 23 181 203 181 203 0.99

5 22 0.00045 0.072 14.7 0.3 1 23 365 388 365 388 0.94

6 22 0.3 48 5.8 0.0 2 23 399 421 398 421 0.88

7 22 0.24 39 6.1 0.1 3 23 491 511 490 511 0.97

8 22 0.099 16 7.3 0.0 3 23 528 548 527 548 0.96

9 22 0.00038 0.061 14.9 0.3 1 23 557 580 557 580 0.94

10 22 2.7 4.4e+02 2.8 0.1 1 23 585 608 585 608 0.91

11 22 9 1.4e+03 1.1 0.2 1 9 615 623 615 628 0.86

12 22 9.1 1.5e+03 1.1 0.1 9 23 639 654 638 654 0.94

13 22 3.3 5.3e+02 2.5 4.8 2 23 683 704 682 704 0.96

14 22 0.0013 0.21 13.2 0.0 1 23 709 732 709 732 0.95

15 22 0.6 96 4.8 0.1 2 23 803 826 802 826 0.88

16 22 5.3e-05 0.0084 17.6 1.0 2 23 842 864 841 864 0.96

17 22 0.042 6.7 8.5 0.8 1 23 873 896 873 896 0.93

18 22 0.0056 0.89 11.2 0.1 2 23 1113 1135 1112 1135 0.95

19 22 0.21 34 6.3 0.3 1 23 1143 1166 1143 1166 0.95

20 22 1.2 2e+02 3.9 0.2 2 23 1179 1200 1178 1200 0.94

21 22 0.0053 0.84 11.3 0.6 2 23 1209 1231 1208 1231 0.94

22 22 0.0087 1.4 10.6 1.1 1 23 1238 1261 1238 1261 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	9.9e-06	0.0016	19.9	1.5	1	23	97	119	97	119	0.98
2	22	0.24	38	6.1	4.9	1	23	125	147	125	147	0.98
3	22	1.3e-06	0.00021	22.7	4.1	1	23	153	175	153	175	0.99
4	22	0.00026	0.042	15.4	0.2	1	23	181	203	181	203	0.99
5	22	0.00045	0.072	14.7	0.3	1	23	365	388	365	388	0.94
6	22	0.3	48	5.8	0.0	2	23	399	421	398	421	0.88
7	22	0.24	39	6.1	0.1	3	23	491	511	490	511	0.97
8	22	0.099	16	7.3	0.0	3	23	528	548	527	548	0.96
9	22	0.00038	0.061	14.9	0.3	1	23	557	580	557	580	0.94
10	22	2.7	4.4e+02	2.8	0.1	1	23	585	608	585	608	0.91
11	22	9	1.4e+03	1.1	0.2	1	9	615	623	615	628	0.86
12	22	9.1	1.5e+03	1.1	0.1	9	23	639	654	638	654	0.94
13	22	3.3	5.3e+02	2.5	4.8	2	23	683	704	682	704	0.96
14	22	0.0013	0.21	13.2	0.0	1	23	709	732	709	732	0.95
15	22	0.6	96	4.8	0.1	2	23	803	826	802	826	0.88
16	22	5.3e-05	0.0084	17.6	1.0	2	23	842	864	841	864	0.96
17	22	0.042	6.7	8.5	0.8	1	23	873	896	873	896	0.93
18	22	0.0056	0.89	11.2	0.1	2	23	1113	1135	1112	1135	0.95
19	22	0.21	34	6.3	0.3	1	23	1143	1166	1143	1166	0.95
20	22	1.2	2e+02	3.9	0.2	2	23	1179	1200	1178	1200	0.94
21	22	0.0053	0.84	11.3	0.6	2	23	1209	1231	1208	1231	0.94
22	22	0.0087	1.4	10.6	1.1	1	23	1238	1261	1238	1261	0.96

Sequence Information

Coding Sequence: ATGCTGTTCAAAGGCAACAGTTCGCGTCTGGAATTGCTGATCGGAAAGATCCAGGCGCACAAGGAATCACCGTCGCCACCACGAGCTGACAAGCGCGGCATCAGGTCCAAAGACGCTCTCGGGACCGGAAGTTCGTCATGGCACAGCGAGGATGGCGGTGCGAATTCGCGACGGGGCGGAGAAACTCCCTCGTCCTGCGCGACTCCAACGTCGGCCAGTTTCCCCTCGGAACCGGAAGTCGATACCGAAGTCGGCATCAACGCCGATGGCAGCAATCCCGTTGCCCCTTATCCCTGCCAATTCTGCGACAGGACCTTTCCGCGACTCAGCTACTTGAAGAAACACGAGCAGAGTCACGGCGATCAGATGCCGTATCGTTGCAGCTGGTGTTCGCGTCTCTTCAAGCACAAGCGAAGCAGGGACCGTCACGTCAAGTTGCACACCGGCGACCGAAGGTATCGGTGCTCCCATTGCGAGGCCGCGTTCTCCAGAAGTGACCACCTAAAGATTCACATGAAGACACACGACAATCAGAAGCCTTATCAGTGCACCGCTTGTTCGCGCGGCTACAACACAGCGGCCGCCCTAACCTCGCACATGCAATCGCACAAGAAGCACGCGAGCCCGAATCAGAACGCGAAGATAGCGGACATTGATTACGGGCGACGAAGCGTCTCGTCGCACAGTACCTCGTCACCGCCGATCCAAAATTCGCCGTCTCCGAGCCTGAATCTTAGCGCAAATCTGAAGAATTCCGTGAAATCGCATCAATCGATGTACAGCAGCGGGAACAACGGCCCGAAAACTCCCACCATGCTGAACTCACCGTTGAAGCTGGCCTGCATGTATTGCACGAAGGACTCGTTCACGAGTATGCACCAATTGCAGTTGCACGTACACGCGATGCATCAAGCGATACTGAACGGGGCGACCTTGAACGTGGAGTCGCCGGGGCAGGCGAATAAGCCGGAAGCCATCAGCTCCATGGGTCGCGATGGGCCTTCCGTTGCGGAAAGAAACAACGAACCCGAGAGAACGTATCGTCGCGATAAGTCCGTTGAACTGGACCGGATGAACATTCTGGAGAGTGCATTCTCTTGCGGGCAGTGCACCATGAAGTTTTCCAGTCTGAGCGAGCTGCGTGATCATCTGTTGGCGATTCATCGAGGCGATGGGTTCGGCTCGAGCCTGATGATGTGTCCACTTTGCGGTATTCCTTGCGCCTCTGCAGCATCCTACGCGGAACACTATGTCCTCCAGCACTGCGAGAATCGTCAGGTGGCTGGCAAGGATTCGCATCATCGAGACTGGGACGTTTCGAGGATGAACGGTAGCCGGGAGAGCAGCCGGGCTGCCTCGGAGGATCAGGGCACGACGAGCAGATCTGATCTTGGAACGTCGGAGCCTGCCGATCTGACGAAGAAACAGGCGAGACCCGGAGATACCGGTTACACAACTGGGACCCTTCTGTGCGGTCAGTGCGGTGCCGCGTTGAAGGACTTCGAGTCCTTTCGCGAACATCTCGCCCGTCATCTTCAAGCCGATCAACAGCAGAACAGCGAACCGTTGCCGAGGAATCCCTGCCCCAAGTGCGCCGCGAGTTTTCCCGAACGCGAGGACATGTTGGCTCATCTCACCAAACATTATCTCGGCCAAGTCACCAAGGAGTACACTTGCGGCGCTTGCGAAAAGTCCTATCCACATCCGGATCTTTTGCAACGTCATCTACTCGACACCCACGCCCATCATTTGTACCGTTGCGCCGTCTGCCGCGACACATTCGACTCCAGAGTCGCCATTCAGGTGCACTTCGCGGTCAAACACAGCCAGGAGTCGCAGGTCTATCGTTGCAACACGTGCAACACCTCGGGCAACGAGAATTCCCCGGGGAATTCGCCTGGCGAGGTGAGAAATTGCTTTCGCACCGAGGCCGAAATGGCCAATCACGTTAGATCGATTCACGCACCATCAGCGAACGTCAGCGAGGAGGCTCCTTTGCGGAGAAGTCCCGCTGTCACGCCAGCCGGTAACGCCGCTGGTACCAGCAGATGCGTCTTTTGCGGCCACTGCTGCAACACGGACTTGGAGCTGCAGCTTCATCTGGCGAGCCACTCGGCCAATCTCTATCGATGCCCGATCTGCAGGGAAGGATTTCCAGTGGAGTTTCTCTTGGAGAGGCACATAGCTCAGGCGCATCGAGCCAGCAGTGATCGGAACGACGGGAGGGAAAATGGAAGGTCCTACAGGGCGTCAAGGTCGCAGGATGAAACGGCAAGGTCACAAAAGCGCGGACGATCGCCAGCCTCGAGCAACAACAATTCGCTGAATCAGCGGGACAACAATAACAAACGAGCGAACTACGGGGCTGTAAGCAACGGAACCGGCACAAGCAGCTCCCTCGTCCAACAATGCGAGCTCTGCGAAAGAGCGGAGTTCACAACGGAAGCGGAACTTCAGGCGCACAAAAAGCTCGTTCACACACCGATCAAGGTACAGGCTAAGTCTCTACCGTTGCTCAGCATGACCTGCGCATACTGCGGCGAGGTATGTCGTTCGCGAAGCGATCTCGAGTCCCACACGAGAATTCAACACGCCTCGAACGAGCCCGGTGGACGTCACAAGTGTAACATTTGCGACGAGGTTTGCCCATCGGGCGGGACATTGGCCGAGCACAAGCTCCAGACTCATTGCAAGATTCAAGTGAGCGACACTTGTATCGTGTGCCGTGGCACTCTGTCGAGCGAGGCCCAATTCGTGGAGCACGTGCAGCGACACAGCCTGGAGAGTGGCGAGTCTCATCAACGTTGTACGGACAGCACGCTTCCTCTTTTGCCGGCGGCTTGCGTCGTTTGTCGTCAGACGCTCATAAGCGATCTTGAGTGTCGCTTGCACGCGACTCACCATTTGAGGCTTTCCAATGTACCTGGAGTGACGAATGCCAGTCCAAGCCCGAATCACCacaagcaacaacaacaacaacaacaactcTTCCAACAGACCAATCTGAGCTGCTGCCTTTGCCTGCGAGACTTCAGCGTCGATGACTTCGTAAGCTTGCCGTCGAATAATCCAACGGGCGCGGGTGGCGGCCCACCTTTGAGGGTCTGCAGACCCTGCTACGTCAGGCACTCCCAAGGCCTGCCCATACTCAGTTCACCCTACGAACACGTGAGACAGTCCAAGAGCGAACGAAACACTTGGTTGAATGGTAAGGATCGCGCCAACAGGGATAACTCGAGGGATCAATGGGATCAGAACGAGAGATCGTATGGCGTTGACGAACGCGACAGGAGCCAAAGCGTGAACACCGGGATTAACGGATCGGATGGTGGCGACAGGTGCGACGAGTGCGGTATCAAGTTTGAGAACTCTGGCGAGGCTGAAACTCATAGGATCAAGGAACACGGCAAAGGAACAAGGAACACTTACACCTGCATacaatgtcagATGTCTTTCCCATCGGAGGAGAAAATTCGTCAGCACGTGAGGAATGTCCATTTGGAATCCTCGAGCAAGTCCTTGAGCGAGGCGTTGCGCTGTCACCTTTGCACATTCGAAGCCAACAGTCCTATCCAGCTCCAGGGGCACTTGATAGAGCACACTTTCGCCGGTTGCGCTGGCCTAACCTGCTACATCTGTCAGGGTCTATTCACGACACCCCATGCACTTCAGAATCACATGCTGCAGCTACACGGACTTGGCGCTCGCCCCTACGACTGCAGCAACTGCGGCCTCAAGTTCTTCTTCCGTATCGAGCTTGAACATCACGAGATGATGGTACATCGCGGTACCGACCCCTCGTCACCCAAAATGCCGGACGCGGCTCGTGAAGTCACACCGGGAAATTGCGAAATGGCCGAAGATTCAGGCATCAAACAGCTGGATGAGGATAATCGCGAGCTGCCTGCATCGAACGCTGTCACGGTGAAGGAAGAAATCGTCGGCAGTCCCAGCGACAAGGAATTCCAGCTGGACGATGATGTCCCGGAAAATGGCGATTCggaaagaaaagaagaagagcCACATTTTCTCGAAGCGAAGACGGAATCTTTTGGAATAACTCACAACGAAGACAACGTACAATCTTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKESPSPPRADKRGIRSKDALGTGSSSWHSEDGGANSRRGGETPSSCATPTSASFPSEPEVDTEVGINADGSNPVAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDNQKPYQCTACSRGYNTAAALTSHMQSHKKHASPNQNAKIADIDYGRRSVSSHSTSSPPIQNSPSPSLNLSANLKNSVKSHQSMYSSGNNGPKTPTMLNSPLKLACMYCTKDSFTSMHQLQLHVHAMHQAILNGATLNVESPGQANKPEAISSMGRDGPSVAERNNEPERTYRRDKSVELDRMNILESAFSCGQCTMKFSSLSELRDHLLAIHRGDGFGSSLMMCPLCGIPCASAASYAEHYVLQHCENRQVAGKDSHHRDWDVSRMNGSRESSRAASEDQGTTSRSDLGTSEPADLTKKQARPGDTGYTTGTLLCGQCGAALKDFESFREHLARHLQADQQQNSEPLPRNPCPKCAASFPEREDMLAHLTKHYLGQVTKEYTCGACEKSYPHPDLLQRHLLDTHAHHLYRCAVCRDTFDSRVAIQVHFAVKHSQESQVYRCNTCNTSGNENSPGNSPGEVRNCFRTEAEMANHVRSIHAPSANVSEEAPLRRSPAVTPAGNAAGTSRCVFCGHCCNTDLELQLHLASHSANLYRCPICREGFPVEFLLERHIAQAHRASSDRNDGRENGRSYRASRSQDETARSQKRGRSPASSNNNSLNQRDNNNKRANYGAVSNGTGTSSSLVQQCELCERAEFTTEAELQAHKKLVHTPIKVQAKSLPLLSMTCAYCGEVCRSRSDLESHTRIQHASNEPGGRHKCNICDEVCPSGGTLAEHKLQTHCKIQVSDTCIVCRGTLSSEAQFVEHVQRHSLESGESHQRCTDSTLPLLPAACVVCRQTLISDLECRLHATHHLRLSNVPGVTNASPSPNHHKQQQQQQQLFQQTNLSCCLCLRDFSVDDFVSLPSNNPTGAGGGPPLRVCRPCYVRHSQGLPILSSPYEHVRQSKSERNTWLNGKDRANRDNSRDQWDQNERSYGVDERDRSQSVNTGINGSDGGDRCDECGIKFENSGEAETHRIKEHGKGTRNTYTCIQCQMSFPSEEKIRQHVRNVHLESSSKSLSEALRCHLCTFEANSPIQLQGHLIEHTFAGCAGLTCYICQGLFTTPHALQNHMLQLHGLGARPYDCSNCGLKFFFRIELEHHEMMVHRGTDPSSPKMPDAAREVTPGNCEMAEDSGIKQLDEDNRELPASNAVTVKEEIVGSPSDKEFQLDDDVPENGDSERKEEEPHFLEAKTESFGITHNEDNVQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01101554;
90% Identity: iTF_01103749;
80% Identity: -