Basic Information

Gene Symbol
-
Assembly
GCA_905475445.1
Location
FR997722.1:18203462-18225510[-]

Transcription Factor Domain

TF Family
AF-4
Domain
AF-4 domain
PFAM
PF05110
TF Group
Unclassified Structure
Description
This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental disabilities [1]. The family also contains a Drosophila AF4 protein homologue Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.3e-12 1.9e-07 32.0 0.0 4 76 46 120 44 129 0.85

Sequence Information

Coding Sequence
ATGGCAATCGCTCGCACACTCAATGCACTCGATCCGGACTACCTCAAACGGCTGTGTTGGTACGACAAGTGGGACCGGGACAGGGGCGGGGGGagcggcggcgggggcggcgggtCAGGCGCGTGGGCCGGCCGCGACCGCGAACGCGACCGCGAGCGCGAGCGACAGGCGCGCGCGCACCAGATGTCGCAGGCGCACGCCGCCGAACCCGACGCATCGTCGCTCTTCCCGGCGCCGTTCAGGGTGTCCGGCAGGCAGGATCGCGTGAGTCAGCAGATCCAGACCAAGCTCGGCGATTACCATCTCGCGCAGTGGTTCATCGATGACCCCAGCAAATCCATTGGGATCTGTGCTGAACCACCAAGTCCTGCACCATGTGAACCTGAGTGGtga
Protein Sequence
MAIARTLNALDPDYLKRLCWYDKWDRDRGGGSGGGGGGSGAWAGRDRERDRERERQARAHQMSQAHAAEPDASSLFPAPFRVSGRQDRVSQQIQTKLGDYHLAQWFIDDPSKSIGICAEPPSPAPCEPEW*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2