Basic Information

Insect: Nephrotoma guestfalica
Gene Symbol: -
Assembly: GCA_963691935.1
Location: OY829913.1:129678202-129701650[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.3e-05 0.0025 20.0 1.8 1 23 569 591 569 591 0.97

2 18 8.7e-06 0.0017 20.5 0.2 1 23 597 619 597 619 0.97

3 18 0.00032 0.062 15.6 0.3 1 23 625 647 625 647 0.98

4 18 2.3e-06 0.00045 22.3 2.5 1 23 653 675 653 675 0.98

5 18 6e-05 0.012 17.9 4.7 1 23 681 703 681 703 0.99

6 18 1e-05 0.002 20.3 3.5 1 23 709 731 709 731 0.97

7 18 7.3e-07 0.00014 23.9 5.0 1 23 737 759 737 759 0.98

8 18 2.2e-07 4.2e-05 25.6 2.5 1 23 765 787 765 787 0.97

9 18 0.00011 0.022 17.0 6.7 1 23 793 815 793 815 0.97

10 18 2.2e-05 0.0044 19.2 6.1 1 23 821 843 821 843 0.98

11 18 1.6e-07 3.1e-05 26.0 3.1 1 23 849 871 849 871 0.98

12 18 9.5e-06 0.0019 20.4 7.7 1 23 877 899 877 899 0.98

13 18 2.6e-05 0.0051 19.0 5.5 1 23 905 927 905 927 0.98

14 18 5.3e-05 0.01 18.0 5.9 1 23 933 955 933 955 0.97

15 18 5.5e-05 0.011 18.0 5.0 3 23 963 984 962 984 0.96

16 18 7.9e-05 0.016 17.5 0.5 1 23 990 1012 990 1012 0.98

17 18 0.013 2.5 10.6 3.9 1 23 1022 1044 1022 1044 0.98

18 18 1.5e-06 0.0003 22.9 4.0 1 23 1050 1072 1050 1072 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.3e-05	0.0025	20.0	1.8	1	23	569	591	569	591	0.97
2	18	8.7e-06	0.0017	20.5	0.2	1	23	597	619	597	619	0.97
3	18	0.00032	0.062	15.6	0.3	1	23	625	647	625	647	0.98
4	18	2.3e-06	0.00045	22.3	2.5	1	23	653	675	653	675	0.98
5	18	6e-05	0.012	17.9	4.7	1	23	681	703	681	703	0.99
6	18	1e-05	0.002	20.3	3.5	1	23	709	731	709	731	0.97
7	18	7.3e-07	0.00014	23.9	5.0	1	23	737	759	737	759	0.98
8	18	2.2e-07	4.2e-05	25.6	2.5	1	23	765	787	765	787	0.97
9	18	0.00011	0.022	17.0	6.7	1	23	793	815	793	815	0.97
10	18	2.2e-05	0.0044	19.2	6.1	1	23	821	843	821	843	0.98
11	18	1.6e-07	3.1e-05	26.0	3.1	1	23	849	871	849	871	0.98
12	18	9.5e-06	0.0019	20.4	7.7	1	23	877	899	877	899	0.98
13	18	2.6e-05	0.0051	19.0	5.5	1	23	905	927	905	927	0.98
14	18	5.3e-05	0.01	18.0	5.9	1	23	933	955	933	955	0.97
15	18	5.5e-05	0.011	18.0	5.0	3	23	963	984	962	984	0.96
16	18	7.9e-05	0.016	17.5	0.5	1	23	990	1012	990	1012	0.98
17	18	0.013	2.5	10.6	3.9	1	23	1022	1044	1022	1044	0.98
18	18	1.5e-06	0.0003	22.9	4.0	1	23	1050	1072	1050	1072	0.97

Sequence Information

Coding Sequence: ATGGGAATAATGGAGTtcgaaaatttacataatttgttaaataataaatttaaaaaaaattgtattcggaCTCTAATTGATCCTGAATTTAGATTGGTTTTGACACTAGAATATTTAGCCCATGGTCTGCATGGCAAATATTGTCATGGAGTTTTCGCATTGAAGGTTGAGCTGAGCAGCATCTACCTGTCTCCACCGACTGAAGAGGAGTACCATATCATTGTTTTGCTAGCAGCATATGACAGCAACAATGTATTTTCggccgtagatcttgttgaaTATGAGAGCCAGAGTGATGGTGGAATTTTGAAACTGAGCGGCTTCGGAAATCAGATATTGCAATGCAATATTAATATACCAAAGACGAAGAAATTGCCTCGAACGAATGAAGAGTTCCCAtgtttctttatcggtgatgcTGCATTTTCATTGCGACACAATTTAATGCGGCCATATCCTGGGCTACTCCTTACAAAAGATAAACAgttgttcaataaaaaattatcatcgtTCAATGGTAAATACTTTTTATTCCAAAACATCAACATAAGTCTTGGTCCCTGTGTTTATAATTTACCTCGCTTTGATGGACCTAAACCCAGTCAGgaaGTTTTATCAACTATAACACCAGATGCATCCATGATTTTGGGTACCAGTCCACATTCTTTACCTATATCACTACCATCCGGATCCGCATTAAATATGCCATCTTCAGTGAATTCAACAGCCCCACATCAATCAAACTTAAATTTGACATCATCACTTCATAGTGGTTTGATCGGTAATGATAATCATCCCAGTGCGTTACATTTACATCCTCCACCACCTCAGCAACAAATGCCACTAGGTCCACCCGATGGTATAGTTATGGATGTCCGCCAAACCCCAAAGGAATTAAAAGTATTTGAGACATCACATTTGGAGCATTTTCAACATCAACAgcagcaacagcagcagcagcaacagcaacaacagcaacaacaacagcaacaacagcagcaacagcaacagcagcaacagcagcagcaacaacaacatcaccaacaacaacagcaacaacaacaacaacagcagcagcaacatcaacatcaatCTCAACCGCCATCACAACAGCAACAATCACAGTTATCACCCTCAAGACATCGACAAGATGTAAACCGCCCTGTGGACCATTCAATTAGTAATTCCGATTCACATCATGTACCTCACACCATAAACTCCgaaattcgaaataataatgAACCTAATCTGAAAGATGCGAAATTACATAATCctaaattaaatatacaaactCTACAACATCAATTTTCCGATCAgcaaaacgatttaaaatcgAATCCAAACCCATCCCAGTTAATGGATGTCAGAACTGCTGATGGTTCGATTGTTAAAATTGCATCCGGTATTCAAGAACAAGATTTAACAATGTACAAAGTAAATATTGatgatttaaatcaatttttaacgtGTCAcgaaatttttggtaaattgcCTAATGATATGTTAGCTATGCCTACGGCTGGAATGTCTACTAATCCAACAAGCAGTGTAAGCACGAGTACCACAACTTCCGCTGTTACCGATAGCCACAGAAATGATTTATGTGCAATTTCACCAAAAGAAGAAAATAGTATTGGACATGACGGATCAGCTTCAGGAAGTGGAATGAGTGAAGATTCAAAAGCTCAGCTTTCACAAGCCGTGCATTCATGTGATATTTGTGGAAAAATGTTTCCCTTTCGTTACCAATTAATAGTACACAGACGTTACCATAATGAGAGAAAACCATTTATATGTCAAGTGTGTGGCCAAGCGTTCAACACATCTGACGAGCTAACAAAGCACGGAAAAGTTCATCTTGGTGGCTCAATGTTTATATGTACTGTTTGCTTTAATGTTTTTGCTAATGATGCTAGTCTTGAACGACATATGAAACGACATTCGGCTGATAAACCATTCTCGTGCGCGATATGCCAAAAAACATTTGCGCGTAAAGAACATCTTGAAAATCACACTCGAAGTCATACAGGTGAAACACCATTTAGATGTCAGTATTGTGCTAAAACGTTTACGCGAAAGGAGCACATGGTAAATCATGTCCGAAAGCATACCGGAGAAACTCCATTTCGTTGTGATATctgtaaaaaatcatttactaGAAAGGAGCATTACATGAATCATGTTATGTGGCATACTGGTGAAACACCTCACCAATGTACCGTTTGTGGAAAGAAATATACAAGAAAAGAACATTTGGCTAATCATATGAGATCACATACGAATGAGACTCCATTCCGCTGTGAAATTTGCGGAAAGTCATTTACTAGGAAAGAGCATTTTACTAATCACATATTATGGCATACGGGTGAAACACCGCATCGCTgtgatttttgttcaaaaacattTACTCGCAAGGAACATCTCTTAAACCACGTACGACAACATACTGGGGAATCTCCGCATCGGTGTgagttttgttcaaaatcatttaCACGGAAAGAACACCTCGTTAATCATATCAGGCAGCACACAGGTGAAACTCCATTTAAATGTACCTACTGTCCAAAGGCATTCACACGGAAAGATCACTTAGTGAATCATATCCGTCAACATACAGGCGAATCACCCCACAAATGCACATATTGTTCCAAATCGTTTACAAGAAAGGAACATTTAACCAATCATGTGCGGCAACATACTGGAGAACTTCCACATCGTTGTCAATACTGTGCGAGATCTTTCACTCGAAAGGAGCATTTAACCAACCATGTCCGAATTCATACTGGAGATTCGCCACATCGTTGCGATTTCTGTCAAAAAACGTTTACTCGCAAAGAATATCTAACAAATCATTTGAAACAGCACAGTCAGGATAATCCAAACTGTTGTAATATATGTTCAAAACCTTTTACACGGAAGGAGCATTTAATAAATCACATGAGTCGATCGCATACTGGTGAGCGTCCCTTTTCCTGCGATGAATGTGGAAAATCATTTCCATTGAAAGGCAATCTGTTATTTCACCAGAGGAGTCATAATAAAGGAAGTACAGCTGAACGACCTTTTCGTTGTGATTTATGTCCAAAGGATTTCATCTGTAAAGGACATTTGGTGTCCCATCGAAGATCACACTCCGATGAAAGGCCACATATATGTCAGCATTGTGGTAAATCTTTTGTAGAAAAAGGTAATCTGTTGCGTCATATGAAAAAGCATGTACTGGATACAGCCCATACACAAATTCCTAAATTGGAGCCAGGAACGCAGTTTGCAGCGCCAAAAGTGGAACCGGGTACACAATTTGCAAGCTTATCTGAGGGAATTTCTACGGCTGTCACTTCAATGGAAACTCCATCAAATAACACCGATGCTATAATTACATCAAATGCATCCTTGTCAAATAACTACAATCCActagataataaaatttcaaattcgcaGCAACAACCCGTTTCTATAATTTCTCATTCTCAGGATCATCAAATGAGTTCTTCGAATGATACGAATCGAACAGGAGGTCCACTACAAATGCATCATTTAAATGCACCACAGGAGCACCATGTAGTATATTAA
Protein Sequence: MGIMEFENLHNLLNNKFKKNCIRTLIDPEFRLVLTLEYLAHGLHGKYCHGVFALKVELSSIYLSPPTEEEYHIIVLLAAYDSNNVFSAVDLVEYESQSDGGILKLSGFGNQILQCNINIPKTKKLPRTNEEFPCFFIGDAAFSLRHNLMRPYPGLLLTKDKQLFNKKLSSFNGKYFLFQNINISLGPCVYNLPRFDGPKPSQEVLSTITPDASMILGTSPHSLPISLPSGSALNMPSSVNSTAPHQSNLNLTSSLHSGLIGNDNHPSALHLHPPPPQQQMPLGPPDGIVMDVRQTPKELKVFETSHLEHFQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQQQQQQQQQQQQQHQHQSQPPSQQQQSQLSPSRHRQDVNRPVDHSISNSDSHHVPHTINSEIRNNNEPNLKDAKLHNPKLNIQTLQHQFSDQQNDLKSNPNPSQLMDVRTADGSIVKIASGIQEQDLTMYKVNIDDLNQFLTCHEIFGKLPNDMLAMPTAGMSTNPTSSVSTSTTTSAVTDSHRNDLCAISPKEENSIGHDGSASGSGMSEDSKAQLSQAVHSCDICGKMFPFRYQLIVHRRYHNERKPFICQVCGQAFNTSDELTKHGKVHLGGSMFICTVCFNVFANDASLERHMKRHSADKPFSCAICQKTFARKEHLENHTRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPFRCDICKKSFTRKEHYMNHVMWHTGETPHQCTVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCEFCSKSFTRKEHLVNHIRQHTGETPFKCTYCPKAFTRKDHLVNHIRQHTGESPHKCTYCSKSFTRKEHLTNHVRQHTGELPHRCQYCARSFTRKEHLTNHVRIHTGDSPHRCDFCQKTFTRKEYLTNHLKQHSQDNPNCCNICSKPFTRKEHLINHMSRSHTGERPFSCDECGKSFPLKGNLLFHQRSHNKGSTAERPFRCDLCPKDFICKGHLVSHRRSHSDERPHICQHCGKSFVEKGNLLRHMKKHVLDTAHTQIPKLEPGTQFAAPKVEPGTQFASLSEGISTAVTSMETPSNNTDAIITSNASLSNNYNPLDNKISNSQQQPVSIISHSQDHQMSSSNDTNRTGGPLQMHHLNAPQEHHVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01457737;
90% Identity: iTF_01052483; iTF_01053655;
80% Identity: -