Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371224.1:123746761-123761896[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.2e-05 0.0026 20.2 1.8 1 23 424 446 424 446 0.97

2 18 8.1e-06 0.0018 20.7 0.2 1 23 452 474 452 474 0.97

3 18 0.00029 0.065 15.8 0.3 1 23 480 502 480 502 0.98

4 18 2.1e-06 0.00046 22.5 2.5 1 23 508 530 508 530 0.98

5 18 5.6e-05 0.012 18.1 4.7 1 23 536 558 536 558 0.99

6 18 9.3e-06 0.0021 20.5 3.5 1 23 564 586 564 586 0.97

7 18 6.8e-07 0.00015 24.1 5.0 1 23 592 614 592 614 0.98

8 18 2e-07 4.4e-05 25.8 2.5 1 23 620 642 620 642 0.97

9 18 0.0001 0.023 17.2 6.7 1 23 648 670 648 670 0.97

10 18 2.1e-05 0.0046 19.4 6.1 1 23 676 698 676 698 0.98

11 18 1.5e-07 3.3e-05 26.2 3.1 1 23 704 726 704 726 0.98

12 18 8.8e-06 0.002 20.6 7.7 1 23 732 754 732 754 0.98

13 18 2.4e-05 0.0053 19.2 5.5 1 23 760 782 760 782 0.98

14 18 4.9e-05 0.011 18.2 5.9 1 23 788 810 788 810 0.97

15 18 5.1e-05 0.011 18.2 5.0 3 23 818 839 817 839 0.96

16 18 7.3e-05 0.016 17.7 0.5 1 23 845 867 845 867 0.98

17 18 0.012 2.6 10.8 3.9 1 23 877 899 877 899 0.98

18 18 6.5e-07 0.00014 24.2 1.6 1 23 905 927 905 927 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.2e-05	0.0026	20.2	1.8	1	23	424	446	424	446	0.97
2	18	8.1e-06	0.0018	20.7	0.2	1	23	452	474	452	474	0.97
3	18	0.00029	0.065	15.8	0.3	1	23	480	502	480	502	0.98
4	18	2.1e-06	0.00046	22.5	2.5	1	23	508	530	508	530	0.98
5	18	5.6e-05	0.012	18.1	4.7	1	23	536	558	536	558	0.99
6	18	9.3e-06	0.0021	20.5	3.5	1	23	564	586	564	586	0.97
7	18	6.8e-07	0.00015	24.1	5.0	1	23	592	614	592	614	0.98
8	18	2e-07	4.4e-05	25.8	2.5	1	23	620	642	620	642	0.97
9	18	0.0001	0.023	17.2	6.7	1	23	648	670	648	670	0.97
10	18	2.1e-05	0.0046	19.4	6.1	1	23	676	698	676	698	0.98
11	18	1.5e-07	3.3e-05	26.2	3.1	1	23	704	726	704	726	0.98
12	18	8.8e-06	0.002	20.6	7.7	1	23	732	754	732	754	0.98
13	18	2.4e-05	0.0053	19.2	5.5	1	23	760	782	760	782	0.98
14	18	4.9e-05	0.011	18.2	5.9	1	23	788	810	788	810	0.97
15	18	5.1e-05	0.011	18.2	5.0	3	23	818	839	817	839	0.96
16	18	7.3e-05	0.016	17.7	0.5	1	23	845	867	845	867	0.98
17	18	0.012	2.6	10.8	3.9	1	23	877	899	877	899	0.98
18	18	6.5e-07	0.00014	24.2	1.6	1	23	905	927	905	927	0.97

Sequence Information

Coding Sequence: ATGAATGCGGAAAATTTGCAATCGGAAGAGAATAATTCGCAACTCGGAGGTCAGTTCAATGGTAAATACTTTTTATTCCAAAACATCAACATAAGTCTTGGTCCCTGTGTTTATAATTTACCTCGCTTTGATGGACCTAAACCAAGTCAGGAAGTTTTATCAACTATAACACCAGATGCATCCATGATTTTGGGCACCAGTCCACATTCTTTACCTATATCACTACCATCCGGATCCGCATTAAATATGCCATCTTCAGTAAATTCAACAGCCCCACACCAATCAAACCTAAATTTGACGTCATCACATCATAGTGGTTTGATCGGTAATGATAATCATCCCAGTGCATTACATTTACATCCTCCACCACCTCAGCAACAAATGCCACTAGGTCCACCCGATGTTATGGATGTCCGCCAAACCCCAAAGGAATTaaaagtatttgagacatcacatttggagcattttcaacatcaacagcagcaacaacatcagcagcagcagcaacaacaacaacaacaacaacagcaacatcagcagcaacagcagcagcaacagcagcagcagcagcaacaacagcagcagcaacaacagcagcagcaacagcagcagcaacaaccacaacaaccacaacaaccacaacaacatcaacatcaatctcaaccgccatcacaacagcaacaatcacagttatcaccctcaagacatcgacatgatGTAAACCGCCCTGTGGACCATTCAATTACTAATTCCGATTCACATCATGTATCTCACACCATAAACGCTGAAATCCGAAATAGTAATGAAGCTAATCTGAAAGATGCGAAATTACATAATCCTAAATTAAATATACAAATTCTACAACATCAATTTTCCGATCAGCAAAACGATTTAAAATCGAATCCAAACCCATCCCAGTTAATGGATGTCAGAACTGCTGACGGTTCGATTGTTAAAATTGCATCCGGTATTCAAGAGCAAGATTTGGCAATGTACAAAGTAAATATTGATGATTTAAATCAATTTTTAACGTGTCACGAAATTTTTGGTAAATTGCCTAACGATATGTTGGCTATGCCTACGGCTGGAATGTCTACTAATCCAACAAGCAGTGTAAGCACAAGTACCACAACATCTGCTGTTACCGATAGCCACAGAAATGATTTATGTGCAATTTCACCTAAAGAGGAAAATAGTATTGGACATGACGGATCAGCTTCAGGAAGTGGAATGAGTGAAGATTCAAAAGCTCAGCTTTCACAAGCCGTGCATTCATGTGATATTTGTGGAAAAATGTTTCCTTTTCGTTACCAATTAATAGTACACAGACGTTACCATAATGAGAGAAAACCATTTATATGTCAAGTGTGTGGCCAAGCGTTCAACACATCTGACGAGCTAACAAAGCACGGAAAAGTTCATCTTGGTGGCTCAATGTTTATATGTACCGTTTGCTTTAATGTTTTTGCTAATGATGCTAGTCTTGAACGACATATGAAACGACATTCGGCTGATAAACCATTCTCGTGCGCGATATGCCAAAAAACATTTGCGCGTAAGGAACATCTCGAAAATCACACTCGAAGTCATACAGGTGAAACACCATTTAGATGTCAGTATTGTGCTAAAACGTTTACGCGTAAGGAGCACATGGTAAATCATGTCCGAAAGCATACAGGAGAAACTCCATTTCGTTGTGATATCTGTAAAAAATCATTTACTAGAAAGGAGCATTACATGAATCATGTTATGTGGCATACTGGTGAAACACCTCACCAATGTACCGTTTGTGGAAAGAAATATACGAGAAAAGAACATTTGGCTAATCATATGAGATCGCACACGAATGAAACACCATTCCGCTGTGAAATTTGCGGAAAGTCGTTTACTAGGAAAGAGCATTTTACTAATCACATATTATGGCATACGGGTGAAACACCGCATCGCTGTGATTTTTGTTCAAAAACATTTACTCGCAAGGAACATCTCTTAAACCACGTACGACAACATACTGGGGAATCTCCGCATCGGTGTGAGTTTTGTTCAAAATCATTTACACGGAAAGAACACCTCGTTAATCATATCAGGCAGCACACAGGTGAAACTCCATTTAAATGTACCTACTGTCCAAAGGCATTCACGCGGAAGGATCACTTAGTGAATCATATCCGTCAACATACAGGTGAATCACCCCACAAATGCACATATTGTTCCAAATCGTTTACAAGAAAGGAACATTTAACCAATCATGTGCGGCAACATACTGGAGAACTTCCACATCGTTGTCAATACTGTGCGAGATCTTTCACTCGAAAGGAGCATTTAACCAACCATGTCCGAATCCATACTGGAGATTCGCCACATCGTTGCGATTTCTGTCAAAAAACGTTTACCCGTAAAGAATATTTAACAAATCATTTGAAACAGCACAGCCAGGATAATCCAAACTGTTGTAATATATGTTCAAAACCTTTTACACGAAAGGAACATTTAATAAATCATATGAGTCGATCGCATACTGGTGAGCGACCCTTTTCCTGCGATGAATGTGGAAAATCATTTCCATTGAAAGGCAATTTGTTATTTCACCAGAGGAGTCATAATAAAGGAAGTACAGCTGAACGACCTTTTCGTTGTGATTTATGTCCAAAGGATTTCATCTGTAAAGGACATTTGGTGTCACATCGAAGATCACACTCCGATGAAAGGCCACATATATGTGAGCAGTGTGGTAAATCTTTTGTAGAAAAAGGTAACCTATTGCGTCACATGAAAAAGCATGTACTGGATACAGCTTATACACAAATTCCTAAGTTGGAGCCAGGAACACAGTTTGCAGCGCCAAAAGTGGAACCGGGCTTATCTGAGGGAATTTCTACGGCTGTCACTTCAATGGAAACTCCTTCAAATAACACCGACGCTATAATTACATCAAATGCATCCTTGTCAAATAACTACAATCCACTAGATAATAAAATTTCAAATTCGCAGCAACAACCCGTTTCTATAATTTCCCATTCGCAGGATCATCAAATGAGTTCTTCGAATGATACGAATCGAACAGGAGGTCCACTACAAATGCATCATTTAAATGCACCACAGGAGCACCATGTTGTATATTAA
Protein Sequence: MNAENLQSEENNSQLGGQFNGKYFLFQNINISLGPCVYNLPRFDGPKPSQEVLSTITPDASMILGTSPHSLPISLPSGSALNMPSSVNSTAPHQSNLNLTSSHHSGLIGNDNHPSALHLHPPPPQQQMPLGPPDVMDVRQTPKELKVFETSHLEHFQHQQQQQHQQQQQQQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQPQQPQQHQHQSQPPSQQQQSQLSPSRHRHDVNRPVDHSITNSDSHHVSHTINAEIRNSNEANLKDAKLHNPKLNIQILQHQFSDQQNDLKSNPNPSQLMDVRTADGSIVKIASGIQEQDLAMYKVNIDDLNQFLTCHEIFGKLPNDMLAMPTAGMSTNPTSSVSTSTTTSAVTDSHRNDLCAISPKEENSIGHDGSASGSGMSEDSKAQLSQAVHSCDICGKMFPFRYQLIVHRRYHNERKPFICQVCGQAFNTSDELTKHGKVHLGGSMFICTVCFNVFANDASLERHMKRHSADKPFSCAICQKTFARKEHLENHTRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPFRCDICKKSFTRKEHYMNHVMWHTGETPHQCTVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCEFCSKSFTRKEHLVNHIRQHTGETPFKCTYCPKAFTRKDHLVNHIRQHTGESPHKCTYCSKSFTRKEHLTNHVRQHTGELPHRCQYCARSFTRKEHLTNHVRIHTGDSPHRCDFCQKTFTRKEYLTNHLKQHSQDNPNCCNICSKPFTRKEHLINHMSRSHTGERPFSCDECGKSFPLKGNLLFHQRSHNKGSTAERPFRCDLCPKDFICKGHLVSHRRSHSDERPHICEQCGKSFVEKGNLLRHMKKHVLDTAYTQIPKLEPGTQFAAPKVEPGLSEGISTAVTSMETPSNNTDAIITSNASLSNNYNPLDNKISNSQQQPVSIISHSQDHQMSSSNDTNRTGGPLQMHHLNAPQEHHVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01457737;
90% Identity: iTF_01054579;
80% Identity: -