Basic Information

Insect: Nebria ingens
Gene Symbol: -
Assembly: GCA_018344505.1
Location: JADQWA010000118.1:175727-182722[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.1e-14 1.4e-10 40.6 0.0 9 70 257 316 251 321 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.1e-14	1.4e-10	40.6	0.0	9	70	257	316	251	321	0.88

Sequence Information

Coding Sequence: ATGGAAACAAGCGAATCAGTGCAAAATCCTGAAAATGGTAAAGATAGTTCAGAAGATTTAGAAGAAACAACTTCGCTAAGCCCAGTTACGGATATCAAACAAGAACTCGATTCAGAACATAATGATGACAACGACAATGCAATGGAAATTGATGAGAGTTCTACCATCGAGGAGGATACTAAATCGGTAGATAGTGAAATTCTTATAAAGAAAGAGAATATTGAGAGTCTGGAAATAGAAACAAATGCACAATGTAGAAAACGAAAACTGGACGATTTAGATGATGATGTGGAAGAGGAGGAGGAGGAATTGTGTGATACTGAAAATTCATCACCCATTGATTTCCTTGGTTTCCCTGATAGCCATTCGGATGAAGTGAAACGTCATGAAGAAAAAAAGGAAAAATTCGAAAAACCTAGTGTGAAGTCTGATAACTTAGTTTTTGATACAGCATTAGGAAAAGGAAAACGTTCACGTATTCCAAACAAAAAATATGAGACTCCAACGATAAGATCATTTTCGAAAAAATCTACTGATAACATCGATTTTGAAGGTGGACCAGAAGTGACTAGTTCGGAAGATGGACGAAACGAGGATGAAAATGAAATACACAAAATGGACGATATATCATCGGAAGTATCTAGTTCAGCCCACAGTAGCCCATCTGTCGGTAATCGGGCGAAGAACTCACGATTGGCGAGTAGCGTTGCAAGTCCGCATAACAAAAAACCGAAATTCACCGTCGATATGACAAACCCGAACTTTTTAAAGCCATTTGACCTCGGCTGGCGACGTGAATTAGTGTATCGTTCCAGTTGCGATAATTACGGACGCCGCAATGGTGACGTTTATTATTACATGCCGACAGGACAAAAAATTCGATCGATGCGCGAATTAGTCGAAACCCTTGATTCACCAGACTTAACACCGGAAGATTTTACGTTTTTTAAAGAACCTGTTGGTTTAAATGACTTAACAAAAGAAATTGTCCGCAATGCTAAAGTAAAAGGAAGTTGGGGCGGTACGCCAGTTTCAAAAAAAGGCACACCGAAAAGCAAAAGTGGTCGAGACCGAACTGCACCAACTCCGGAAATTGGAAAATCGCCACGGTTAGGTGGATTTAAGGTCAAGATTCCTGGATCATCACGATTGAGCCAAGGAGCGCAGAAATCCGATCGTAAACGTTCCGTGGATAGTGATATGGAGATGGGTATGCTGCCACCGGTTTGGTCGCCCAAGAAGGGTTCCGCGTCAAAGCAGTCTACATGGCAGGCAAAAACTGGCAGCCTAACGATCGCACCGTTGGACTCTAAAAGATGTCATCCGTGCTCTATCCGGTGCCAGGGTGTATCGGGTCTAATACCGACATTGCAGTGTCGTTTATGTCTCTGCTTATACCACAAAGAGTGTGTTGGTGAAGCAAGCGATGATGTTCCGTCTGGCTACGTGTGTAAGAATTGCCAACTGGACAGTCAAGATAAATTAGATACTTCGTTTATTCCTACACCAGGTCCGCCTCCTTTAACTCCAATAAGTTCTCTGAAATCCAATAATTTACTATCCTCCTTGCCACCAAAACTCCATAAAATACCGCGGCCTGGCGAGAAATTATACCTTCAATCTAATACTCCTCATTTAACCAAACAAACTTTACTCCCTAAAAAATCTGATCTTAAATCAAACAAATTTGCACCGTCAGCACGTTATTCAAATAATATTGAACCCAGCAATAAAAGTTCAGTCAGATCTATGACTACATGGCTGGCACCTAATTCTACCATTAAAATGAATGCTAATAATAATAATAGTGTAAGTGATGATTTAATCTCACCCAAACCTCAAGGTTTGGTTATAATGGGAGAAAGAAAATTTTTAGTTGTTCCCAAAGGAAATGTATTATCTATTTCACCTACTGTTGGAGCAGCAGCTAATACTCCTAGTAGCAAACATTTGGTGTCGCCAACTGCTGACAAGGCACCGGTGTTTGAATCAAATTTTAAAGAAAAGAGTAAATTATTGGACGGTGCAATTCCGAATGCTCCAGTGTCTGCATCTTTCGGTCCTATATCCTTATCAGCAAATGCATCTTCTCCTGCGATTATAGATAAACCAACTCATCCCGATTCCTCTGAAGCACTTCCAGGGCCGGTTGATTCCAAACGGGACGTGGCTGCCAAGACTTCGTTCGGCGAAACGCTTAAAGAAAATCAACGGGAACCATCGCCACCGAAAACCAGAAGAAGCGTTACTCGAAAAACAACATTAATCCCAGCCGCAGTTCCAAAGTTGGATGCCGAGACACGATTCATGCAAAACTACTTGCAGAATTTGTCGTACGGCTATCAGACACTTATGTATGTGTTTCAATACTTAAAAGTTCAAGATTTATTACGTGCTGGTTGTGTGTGTACGTTATGGCGTGACATCGCCGCACACCCAAGCTTGTGGAGGACTGTTCGTATGAAAAATTCACAAGTGTCGAACTGGGAAGGATTAGCAGACGCACTAAAAAAACACCGTACCGAAAACCTAGATCTCCGCAAAATGCTCTTGCCTAACTCTGGCGATGACATGTGGCCATTATTTTCAAAAGCAATAGTACGCGTCGATTCCCTAATTCGAATAGAATTGTGCCGTTGTCCAGCTTCTGTTATAGAAGAATTGGCTAAATCAAACAGCAATTTACAAGTTATTAACGCAGTAACAATCCGTTGCGAAACACTCGACGTTAGTTCAATGTCGAATGTTGCGAATTTACAAGAATTAAGACTAAAGTCTACAAATGGATTCGCGTTGACATCGGATTTATCACCATTGAAACAACTGACAAAGCTGAAACATTTGTCACTGACGTCAGTTAAAGAACTGAATAAACAGAACGTGGAAATCATTGGAAATTTAATCAATTTAGAATCGTTAGATTTGGGGGAATGTAGCGATTTTCCTGATCATTTTGGAACTGATGTTATTGGGAAATTGACAAAATTAGAAAAACTTCGTTTGGAAAAAGGACAAGGTACATGTTGTACCTTTGATATTTTGGACGCAGTTAGCAAAATTTCCTCTTTGGAACAATTGGAATTAGTTAATTTCGATGTTAAGGCTGGTTTTGATAAAGCACTTGGAGCATGTATGAATATAAAAAAGCTACTGATCATCCCTACATACATATCACAATCGGCAACTACAAATCACATGGTGCTGGGTGGTGTTATAAAATTGAAAGCGACGTTATCGCATTTCGTTTGGGGTGTAACACTGGAATTGCTGCGAGTCACAGAATTGTTTGTAGATCAATGCGAAGATTCACCGAATAAAGACAAAAAGAAATCCGCGGGTAACGGAGATAGCATACCTGTGCTGAAACCGGTACCAATAATGAAAATTGAGGAGACTAATGAAGTAACAAGTAAAGAACCACCACAAGTAGAAATATTACCGTTGCCGACCCTACAAAAATTATTGCTCAATGCGTTGCCGACGACGCGGGTGAAAATATTAAAAATCCCATTCCACGCGACATGGCGACAAAGCATCGTGGACACCGTTAATTAA
Protein Sequence: METSESVQNPENGKDSSEDLEETTSLSPVTDIKQELDSEHNDDNDNAMEIDESSTIEEDTKSVDSEILIKKENIESLEIETNAQCRKRKLDDLDDDVEEEEEELCDTENSSPIDFLGFPDSHSDEVKRHEEKKEKFEKPSVKSDNLVFDTALGKGKRSRIPNKKYETPTIRSFSKKSTDNIDFEGGPEVTSSEDGRNEDENEIHKMDDISSEVSSSAHSSPSVGNRAKNSRLASSVASPHNKKPKFTVDMTNPNFLKPFDLGWRRELVYRSSCDNYGRRNGDVYYYMPTGQKIRSMRELVETLDSPDLTPEDFTFFKEPVGLNDLTKEIVRNAKVKGSWGGTPVSKKGTPKSKSGRDRTAPTPEIGKSPRLGGFKVKIPGSSRLSQGAQKSDRKRSVDSDMEMGMLPPVWSPKKGSASKQSTWQAKTGSLTIAPLDSKRCHPCSIRCQGVSGLIPTLQCRLCLCLYHKECVGEASDDVPSGYVCKNCQLDSQDKLDTSFIPTPGPPPLTPISSLKSNNLLSSLPPKLHKIPRPGEKLYLQSNTPHLTKQTLLPKKSDLKSNKFAPSARYSNNIEPSNKSSVRSMTTWLAPNSTIKMNANNNNSVSDDLISPKPQGLVIMGERKFLVVPKGNVLSISPTVGAAANTPSSKHLVSPTADKAPVFESNFKEKSKLLDGAIPNAPVSASFGPISLSANASSPAIIDKPTHPDSSEALPGPVDSKRDVAAKTSFGETLKENQREPSPPKTRRSVTRKTTLIPAAVPKLDAETRFMQNYLQNLSYGYQTLMYVFQYLKVQDLLRAGCVCTLWRDIAAHPSLWRTVRMKNSQVSNWEGLADALKKHRTENLDLRKMLLPNSGDDMWPLFSKAIVRVDSLIRIELCRCPASVIEELAKSNSNLQVINAVTIRCETLDVSSMSNVANLQELRLKSTNGFALTSDLSPLKQLTKLKHLSLTSVKELNKQNVEIIGNLINLESLDLGECSDFPDHFGTDVIGKLTKLEKLRLEKGQGTCCTFDILDAVSKISSLEQLELVNFDVKAGFDKALGACMNIKKLLIIPTYISQSATTNHMVLGGVIKLKATLSHFVWGVTLELLRVTELFVDQCEDSPNKDKKKSAGNGDSIPVLKPVPIMKIEETNEVTSKEPPQVEILPLPTLQKLLLNALPTTRVKILKIPFHATWRQSIVDTVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01039234; iTF_01040874; iTF_00873045;
90% Identity: iTF_01039234; iTF_01040874;
80% Identity: -