Basic Information

Insect: Leistus spinibarbis
Gene Symbol: -
Assembly: GCA_933228875.1
Location: CAKOGB010000071.1:1085016-1091463[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.3e-14 1.3e-10 41.1 0.1 8 70 249 309 244 314 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.3e-14	1.3e-10	41.1	0.1	8	70	249	309	244	314	0.89

Sequence Information

Coding Sequence: ATGGAGACAAGTGAATTAGTGCAAAATCCGGAGAACGGTAAAGATAGCTCAGAGGATTTAGAGGAAACGTCGACGAGTCCAGTTACGGATATCAAACAAGAAGAGCGTAATGATGAAAACGGCAAACGGACCGAAATGGATGAACAGACCGGCGAGGAGGAGGCAAAAGTGGTTAAGAGTGATGTAGAAGTGAAACAAGAGGAGATTGATAATGCTGATGTAGAAACAAATGCACCAAGTAGGAAAAGGAAACTGGATGAAATTGATGATGAGGAGGAGGAGGAGGAGGAGGAATCGAGCGAGAATGAGCATTCGTCGCCCATTGATTTCCTTGGTTTCAGCCATTCGGATGAAGTGAAACGTCATGAAGAGAAAAAGGAAAAACTCGAGAAGCCTAGTGTGAAGTCAGATAACATAATTTTTGATACAGCGTTAGGGAAAGGGAAACGATCGCGTATTCCGAACAAAAAATATGAGACTTCAGCGATAAGATCATTTTCAAAAAAATCTACTGATAACATCGACTTCGAAGGTGGACCAGAAGTGACAAGTTCGGAGGATGGGCGCAACGAGGACGAGCACGAAGTCCACAAAATGGACGACGGATTATCGGAAGTATCGAGTTCAGCGCACAGCAGTCCATCTGTCGGCAATCGCGGCAAGAACTCTCGACTGGCTACTAGCGGCGCAAGTCCGCACAATAAAAAGCCAAAATTCACCGTTGACATGACAAACCCAAACTTTTTAAAACCATTCGAGCTCGGCTGGCGTCGCGAACTAGTGTACCGCTCAAGTTCCGATAGTTACGGCCGAAGAAATGGCGACGTTTACTATTACATGCCATCCGGTCAAAAGATACGATCGATGCGTGAATTGACTGAAACACTAGACTCGCCCGACTTAACACCCGAGGATTTTACATTCTTTAAAGAACCCGTTGGTCTGAATGACATCACACGAGAAGTGGTGCGCAACGCTAAAGTAAAGGGGAGTTGGGGACATACAGCGAATGTAAAAAAAGGTACGCCGAAAAGCAAAAGTAGTCGAGAGCGCAATGTGCCTGTCACTCCGGAAATTGGAAAATCGCCGCGGTTAGGCGGATTTAAGGTTAAATTCCCGGGGCCTTCGCGATTGAGCCAAGGCGCGCAGAAAAATGATCGCAAACGGTCAGTGGATGGGGAAATGGAAATTGGGATGCTGCCGCCGGTTTGGTCACCGAAGAAAGGGTCTGCGTCGAAGCAGTCTTCATGGCAGGCAAAAACTGGCAGCTTAACGAACGCATCGTTGGACTCGAAACGATGTCATCCATGCTCTATCCGGTGCCAGGGTGTATCTGGTCTAATACCGACATTGCAGTGTCGTTTGTGTCTCTGCTTGTACCACAAAGAGTGTGTTGGCGAAGAAAGCGACGACGTGCCATCTGGCTACGTATGCAAGAATTGCCAACTGGACAACCAAGATAAATTAGAACCACCATTTCCTCCCACAATATGTCCACCTCCCTTAACTCCAATCACTTCCTTAAAGTCCAACAATTTGCTATCGTCCATTCCGCCAAAATTGCATAAAATACCTCGACCCGCCGATAAACAATACCTTCAATGCACTCCACGCATGTCTAAGCAAACTCTTCTCCCCAAAAAATCTGAACTAAAATCACACAAATTCGCACCATCAGCACTTTATTCAAATAATATTGAAAGCAACAATAAAAGTGCAGTCAGATCTATGACTACATGGCTAGCACCTAATTCTACAATTAAAATGAATGCGAATAATAATAGTGTAAGTGATGATTTAGTATCCCCTAAGCCCCAAGGGCTGGTTATAGTGGGTGAGCGAAAGTTTTTAGTTGTACCCAAAGGGAATGTGCTCTCTATTTCGCCAACGGTTGGTGCAGCCGCTAATACTCCTAGTAGTAAACGCTTAGTAACCCCAACTGCGGATAAAGCTAGTTTTGATGCGAATGCGAAGGAAAAGAGTAAATTGTTGGACGGTGCAATTCCAAATGCCCCAGTGTCCGCGTCTTTCGGTCCTATATCCTTGCCAGCAAATGTGGCTTGTCCTGCGGTTATAGATAAACCAACGCACTCCTCTGAAGCACTTCCTGGGCCGGTTGACTCAAAACGGGACTTGGCTGCCAAGACTGCGTACGGCGAAACGCCTAAAGAAAACCAGCGGGAACCGTCTCCGCCGAAGACCCGAAGAAGCGGCATGCGAAAATCAACAGTAACGCCAGTGCCGGCGCCAAAGCTGGACGCAGAGACACGCTTCATGCAAAACTATTTACAGAATTTGTCGTACGGTTATCAGACACTAATGTATGTGTTTCAATATTTAAAAGTTCAAGATTTATTACGTGCCGGTTGTGTATGTACGTTATGGCGTGACATCGCCGGACACCCAAGCCTGTGGAGGACAGTTCGCATGAAAAATTCACAAGTGTCCAACTGGGAAGGATTAGCAGACGCACTCAAAAAACACCGTACCGAAAACCTAGATCTTCGCAAAATGCTATTGCCCAGCTCTGGCGATGATATGTGGCCATTATTCTCAAAAGCGATTGTACGCGTCGACTCCCTAATTCGAATAGAACTGTGTCGTTGTCCAGCTTCTGTTATTGAAGAATTGGCTAAATCAAACAGCAATTTACAAGTTATAAACGCTGTAACAATTCGTTGCGAATCACTAGACGTGAGTTCTATGTCGAATATTGCGAATTTACAAGAGTTACGATTAAAATCTACAAATGGATTTGTGTTAACAACGGATTTATCACCGTTGAAACATCTGACAAAATTGAAGCATCTATCACTGACGTCCGTTAAAGAACTGAATAAACAAAGCGTTGATATAATTGGCAATTTGATAAATCTAGAATCGTTAGATTTGGGGGAATGCAGCGATTTCCCAGAACATTTTGGGACTAATGTAATTGGCAAATTGACAAAATTAGAGAAACTACGCTTGGAAAAAGGACAAGGTACATGCTGCACTTTTGATATATTGGATGCGGTTAGCAAAATTGCCACTCTGGAGCAGTTGGAATTAGTTAACTTTGATGTTAAAGCTGGCTTTGATAAGGCACTTGGAGCTTGCACGAATATAAAAAAATTGCTGATTATCCCTACTTACATATCACAGTCAGCTACTACGAACCATATGGTCTTGGGTGGTGTTATAAAATTAAAAGCGACATTGTCGCATTTTGTATGGGGTGTAACACTAGAGTTGCTCCGCGTAACCGAATTATTTGTCGATCAGTGCGAAGATTCACCGAACAAAGACAAAAAGAAGCCGGCGGGTAATGGGGATAGTATACCGGTGTTAAAACCGGTTCCAATCATGAAAACTGAGGATACTAATGAAGTATCGAGTAAAGAACCACCACAAGTGGAAATATTGCCGCTACCTACTCTACAAAAGTTATTGCTTAGTGCGTTGCCGACAACGCGGGTGAAAATCTTGAAAATCCCGTTCCACGCGACGTGGCGGCAAAGCATCGTCGACACCGTTAACTAG
Protein Sequence: METSELVQNPENGKDSSEDLEETSTSPVTDIKQEERNDENGKRTEMDEQTGEEEAKVVKSDVEVKQEEIDNADVETNAPSRKRKLDEIDDEEEEEEEESSENEHSSPIDFLGFSHSDEVKRHEEKKEKLEKPSVKSDNIIFDTALGKGKRSRIPNKKYETSAIRSFSKKSTDNIDFEGGPEVTSSEDGRNEDEHEVHKMDDGLSEVSSSAHSSPSVGNRGKNSRLATSGASPHNKKPKFTVDMTNPNFLKPFELGWRRELVYRSSSDSYGRRNGDVYYYMPSGQKIRSMRELTETLDSPDLTPEDFTFFKEPVGLNDITREVVRNAKVKGSWGHTANVKKGTPKSKSSRERNVPVTPEIGKSPRLGGFKVKFPGPSRLSQGAQKNDRKRSVDGEMEIGMLPPVWSPKKGSASKQSSWQAKTGSLTNASLDSKRCHPCSIRCQGVSGLIPTLQCRLCLCLYHKECVGEESDDVPSGYVCKNCQLDNQDKLEPPFPPTICPPPLTPITSLKSNNLLSSIPPKLHKIPRPADKQYLQCTPRMSKQTLLPKKSELKSHKFAPSALYSNNIESNNKSAVRSMTTWLAPNSTIKMNANNNSVSDDLVSPKPQGLVIVGERKFLVVPKGNVLSISPTVGAAANTPSSKRLVTPTADKASFDANAKEKSKLLDGAIPNAPVSASFGPISLPANVACPAVIDKPTHSSEALPGPVDSKRDLAAKTAYGETPKENQREPSPPKTRRSGMRKSTVTPVPAPKLDAETRFMQNYLQNLSYGYQTLMYVFQYLKVQDLLRAGCVCTLWRDIAGHPSLWRTVRMKNSQVSNWEGLADALKKHRTENLDLRKMLLPSSGDDMWPLFSKAIVRVDSLIRIELCRCPASVIEELAKSNSNLQVINAVTIRCESLDVSSMSNIANLQELRLKSTNGFVLTTDLSPLKHLTKLKHLSLTSVKELNKQSVDIIGNLINLESLDLGECSDFPEHFGTNVIGKLTKLEKLRLEKGQGTCCTFDILDAVSKIATLEQLELVNFDVKAGFDKALGACTNIKKLLIIPTYISQSATTNHMVLGGVIKLKATLSHFVWGVTLELLRVTELFVDQCEDSPNKDKKKPAGNGDSIPVLKPVPIMKTEDTNEVSSKEPPQVEILPLPTLQKLLLSALPTTRVKILKIPFHATWRQSIVDTVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01040125;
90% Identity: -
80% Identity: -