Mhyp003107.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Microctonus hyperodae
Gene Symbol
Hr39
Assembly
GCA_030347285.1
Location
JAQQBR010000003.1:2258905-2262328[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 0.62 2.2e+03 -2.6 2.0 52 83 37 68 15 97 0.44
2 5 1.8 6.6e+03 -4.2 19.0 44 163 251 354 233 397 0.41
3 5 4 1.4e+04 -5.5 7.3 64 129 385 452 361 488 0.63
4 5 7.6e-08 0.00027 20.1 0.0 1 21 557 577 557 581 0.92
5 5 8.3e-71 3e-67 227.5 0.0 182 408 694 915 590 915 0.84

Sequence Information

Coding Sequence
ATGTCAGAGCATAACGGGCCCACGGAGGGCCCGGGCTGGTGGACACCAACAGCACAATCATGGAAATCATCATcgtcaaataattcaattgcgTCATCATCCACAACAAACGCAAACAAcacaacaaatacaaatatcattaataataataacaacaacaataatagtaataacaataacaataatgcaTCAACATCAACGTCTTTACGTAGTGGCGAAGCGGGAAAAAATGTTTCTGTAACGACAATAAATGTTCCGCCATTGTCAGATATGCACgatggCAAAAGTGTGAAATATTTGGGAGGTCAAAATGGCGTAACTGTATCAGTAGTGTCATCATGTGGTAGCAGTCCAAGTCCTGGTCTCATGAGCCATGACACAAATTCCATTGATGATCTTGAAGATAGCGATGGTGAAGTGAGCAAAATTGATTTTCGTGGTGTTAATTTACGAACTAAAAAGAAACGCGATGGCGATATCAGTGAATCGTCTACATGTTTTGATGATGTTCATCATCAACAGCCAGAACGTCCAATGTCATGGGAGGGTGAATTATCAGATCAAGAAATGTCTTCCAATACAATTACAAATCAAGATCATGAAGAAACGTCAATGGAGGGTGTACAAGTTTGTGGCGCGAGTCCGGGGCCGCAGGAgcaaaaatttccaattaaacCTGAGCCCGATTTTCGATCGAGTCCCGCCGTGGGAATTAATTCACACATTGACACATCAATACCGATTCATGCACAGCAACAATTGCAACagcaacatcaacaacaacatcaccatcagcagcagcaacagcagcagcagcaacatcaACAAAGCCATCCACAGCAACGTGAACTTGAGCAAAATCAACAAAGTGATTTACCATTACTCGTTGGTAAACTTCTTGGcggatataataattcaacgccCAATCACAGTCCCGTCTTAAATCCCCGTCATCATTTGACAAAGCACAGTCATACAAGATCCCAAGTGCCGTCACCCGATTCTGCAATTCACTCAGCATACAGTGTATTTTCATCGCCGACCCAGAGTCCACATGCTGCACGGCATTCAGCGCTTGGAGCTGGTAGTCCAGTGCCATCATCATCACTCTCACTATCACGTCATAGTTTCAACAATTCCACTTCGTCATTATCACTGTCACATTCATTATCGCGAAATAATTCAGACGCATCAAGCAGTTGTTACAGTTACGGTTCACTAAGTCCGCCCACACATTCGCCCGTACAACAACCACGTCACGCCCATccacaacatcatcatcaagtACCGCAGGGTAGTCCTTTACACCTGCCAACAACGTCAACTAATAACGCCCACCATCATTATTCAAATGCATCAAATGAACTTGGCTCTGAGGGACACTCTGAAGATCCAGAGGATTGTAAAATTCCCTCTGCACCACCGGGTATTTCAACTAGACAACAGTTGATTAATAGCCCGTGTCCGATATGCGGTGACAAAATAAGCGGATTTCATTATGGaatattttcatgtgaatCGTGTAAAGGATTTTTCAAACGAACCGTTCAAAATCGTAAGAATTATGTTTGTTTAAGGGGCGCCGGTTGTCCAGTTACAGTCGCAACACGAAAAAAGTGTCCGGCTTGTCGTTTTGATAAGTGCTTAAATATGGGAATGAAATTAGAGGCAATTAGAGAAGACAGAACACGCGGCGGTAGAAGTACGTATCAATGTACGTATACATTACCGGCGAATCTTATTGGCAGTCCGGCTGGTAGTGTTGCCGGTGATAAAATGACTGGTGGTACATGTAGTCCCGCACCACCTGGCTCTGATCATCATCATTCTGCGCGCCATCATTGGAATCATAAAGTCCAAGTTGTACCACAATTACTTCAAGATATTATGGATGTGGAACATCTTTGGCATTATAACGATAATGATCGTGTTAGTCAAGGTAGTAATGGTCCTGTGAATATGGATCCGTGTGGTTTAGGTTTGAGCGGCGAGGGAAATAGTAATGGTAATGTTGATAGTAGAAGAGAATCATCTAGGCCTAATTCAACAGGTCCACCTGTAGCTCCTAATCATGAACAATCATCACCAACGACAACAAATCCAACATCCGGAAATAATCCAACTACAAATCCAAATGGTAATTCATCGCAACAACCAGATTTCCTATCGAATTTGTGCAATATTGCTGATCATCgactttataaaattgtcaagTGGTGTAAAAGTTTaccattatttaaaaatatttcaattgacgatcaaatatgtttattaataaattcatggtgtgaattattattattttcatgctGTTTTCGTAGTATGAGTACACCAGGTGAAATACGTGTATCACTTGGTAAATCAATTACACTTGAACAGGCACGTCAACTTGGATTGGCAACGTGTATTGAGCGTATGCTTGCATTTACGAATAATTTACGACGATTACGCGTTGATCAGTATGAATATGTTGCAATGAAAGTAATTGTATTATTGACATCAGATACAAGTGAATTAAAGGAACCCGAAAAAGTTCGTGCATCACAAGAGAAAGCACTTCAAGCATTGCAGCAATATACAATCGCTAGGTATCCAGAAATGCCGgcaaaatttggtgaattattattacgaaTACCGGATTTACAGAGAACGTGTCAAGCGGGCAAAGAATTGCTCAGTCAAAAGCGCGCAGAAGGCGAAGGCAGCTCATTTAATCTTCTCATGGAACTTTTGCGTGGTGATCACTGA
Protein Sequence
MSEHNGPTEGPGWWTPTAQSWKSSSSNNSIASSSTTNANNTTNTNIINNNNNNNNSNNNNNNASTSTSLRSGEAGKNVSVTTINVPPLSDMHDGKSVKYLGGQNGVTVSVVSSCGSSPSPGLMSHDTNSIDDLEDSDGEVSKIDFRGVNLRTKKKRDGDISESSTCFDDVHHQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCGASPGPQEQKFPIKPEPDFRSSPAVGINSHIDTSIPIHAQQQLQQQHQQQHHHQQQQQQQQQHQQSHPQQRELEQNQQSDLPLLVGKLLGGYNNSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHAHPQHHHQVPQGSPLHLPTTSTNNAHHHYSNASNELGSEGHSEDPEDCKIPSAPPGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLIGSPAGSVAGDKMTGGTCSPAPPGSDHHHSARHHWNHKVQVVPQLLQDIMDVEHLWHYNDNDRVSQGSNGPVNMDPCGLGLSGEGNSNGNVDSRRESSRPNSTGPPVAPNHEQSSPTTTNPTSGNNPTTNPNGNSSQQPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSQKRAEGEGSSFNLLMELLRGDH