Basic Information

Insect: Microchrysa polita
Gene Symbol: lola_3
Assembly: GCA_949715475.1
Location: OX454415.1:164030715-164032800[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 1.5e-25 8.2e-23 81.8 0.5 3 102 26 122 24 130 0.93

2 2 8.2 4.5e+03 -1.0 0.0 32 69 438 474 437 487 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	1.5e-25	8.2e-23	81.8	0.5	3	102	26	122	24	130	0.93
2	2	8.2	4.5e+03	-1.0	0.0	32	69	438	474	437	487	0.81

Sequence Information

Coding Sequence: ATGGGCAATACGGACACACAAACCTACTGCCTGCGATGGAACAATCACAAATCCAATTTGGTCGAAATTCTCGACGCACTCATCAAAATGGAGAGCTATGTCGACTGCACCCTAATCGTCGAGgatcaaattcaattcaaagcCCATCGTGTCGTGCTAGCGGCCAATTCGCTGTTTTTCCAAAGCATTTTGCAAGACTTCCCCATGGACGATTGTAGTATCATCATTCCCGAAGTTCAGGCATTTGAAATGCGTGCCTTATTGGAATACATGTACACGGGTGAGGTGAACGTGACGCAAAgtcaaattccaaaaattatggaaattgCCGAAAAGCTGGGCGTAAAAGGTCTCTTTGATATGACCGATTTCAAAGAGAAGTTCAACAAAACCGATAAGACCCGATCTAAGACGCCCGTTTCGCAAGGACCATCGAGCATGCCACCGAAAAAGGAAATTGGCGGCGAACATTTGCCTTCGTCGCCGCAAATCAGCACTTCAACAACCGTCGCCACGGCACAAAGTTGCACTTCATCCCCGCCGTACAATTTCAAACCATCGTATTCGAATATGTATGCAAAAAGTGCCGCCGATCCGTCAACATCGGAACGACCCAATTCAGTGCCATGGCCCATTTCGTCTCACCTGTCGGCCGCAATTCCGAGTGCTGCAGCCGCGGCTGCGGCAATGTTGAGCTCTGTCTATGAATCTGGTCCGGATATGAACCCGTTGAAACGAAAAAAGATCTCCTCCATGTCGAATATGTTGATGACACGCGATACACCAATTTTGAGAAATGTCCTTGCCCAGACCCATGCTGCCGACTCGTCCCAACCTATGCCACTTGTGTGTCAGCCAGTCAAGCAGGAAAGTCGCGTGGAAAAGATCGCGGAAAATTGCAATGGATCAGAGTACAATGATAAGAAATACAAATACGATTCACCCGAGCCCCATTCACCCTACGGCGATAAGTCCTTTGACGATGACATGGACATGTCGCCCAACTATGCCAACGATTCTCGTCTCGCCTCCTACGTTCCGCAACAGCAACAGAAACCCGAATGGAAGCGTTACAAACAGTATACACGAAGCGATATCCTTTCGGCCATCGATTGTGTACGCAATGGAATGAGTGCTTTGCAGGCATCGCGCAAATTCGGTGTTCCATCGCGTACGCTCTACGATAAGGTGAAAAAGCTTGGCATTACAACCGCTCGACCGATGAACCGAACGATGAAGCGTAGCCCGAGCAGTGGCGGAGCCCAGGGTGGCTTCCCGTTCGGACTGGGTGGCGGTCACCCGTATGGCAGTGCCAACGAACAAATTCTTCAACAGTTGCACGAGAATAGCGAACGTGAAAAGGAACAACGCGAACATCAATTGCCACCCACCATTCCACATCGGGCAGCCGCTCTTTTGGATCCCGTCTTTTTGCAACAGGCGTTTGAATCGCGTGGCGGCGAGATAGCCGGTCGTGACGCCCTACATGCCATGGCGCTGGCTGCGGCGGCACATGCTGCCGCCAACGGTATTTCAACGAGTCCTGGTACAAATGGCACGGCACGATCGCCTAGCCCGATTAAATATTCGTCCGTTCGATCGCATAGCCCGGTGAGTATGCGTGATCGTGAGCGGGAACAGGAGCGTGAACGGGAACGTGAACGGGAACGCGAACGTGAACTTGAAAGCGATCGTGACTATCAGCGACACGCGGCCGACGACGATGACGAAGATCAAGTCGAAGATCTGTCGGTTGGAGCCCGAAAAGAAGATCCACGAGCATCGCCACATTCACGTTCCAGTCCAATTTCGCATGCCTATCAGCTACAGCAGGAACAACGCCATCAACAAATTCTCCAGCATCATCATCTGCAGCAACAAACCGGTGTCATCGTACCGCCTATGACCACCAAGGTGTCGTCAAACGGTGGTGCCGGTGAAGATTACTCGTACGAAATGAAACGATCCGTTTCGCCCGCGGAGGAATCAGCAATCTCCGCAAGGGAGTAG
Protein Sequence: MGNTDTQTYCLRWNNHKSNLVEILDALIKMESYVDCTLIVEDQIQFKAHRVVLAANSLFFQSILQDFPMDDCSIIIPEVQAFEMRALLEYMYTGEVNVTQSQIPKIMEIAEKLGVKGLFDMTDFKEKFNKTDKTRSKTPVSQGPSSMPPKKEIGGEHLPSSPQISTSTTVATAQSCTSSPPYNFKPSYSNMYAKSAADPSTSERPNSVPWPISSHLSAAIPSAAAAAAAMLSSVYESGPDMNPLKRKKISSMSNMLMTRDTPILRNVLAQTHAADSSQPMPLVCQPVKQESRVEKIAENCNGSEYNDKKYKYDSPEPHSPYGDKSFDDDMDMSPNYANDSRLASYVPQQQQKPEWKRYKQYTRSDILSAIDCVRNGMSALQASRKFGVPSRTLYDKVKKLGITTARPMNRTMKRSPSSGGAQGGFPFGLGGGHPYGSANEQILQQLHENSEREKEQREHQLPPTIPHRAAALLDPVFLQQAFESRGGEIAGRDALHAMALAAAAHAAANGISTSPGTNGTARSPSPIKYSSVRSHSPVSMRDREREQERERERERERERELESDRDYQRHAADDDDEDQVEDLSVGARKEDPRASPHSRSSPISHAYQLQQEQRHQQILQHHHLQQQTGVIVPPMTTKVSSNGGAGEDYSYEMKRSVSPAEESAISARE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00322350;
90% Identity: iTF_00999504;
80% Identity: iTF_00999504;