Math038035.1
Basic Information
- Insect
- Mellicta athalia
- Gene Symbol
- -
- Assembly
- GCA_905220545.1
- Location
- HG992202.1:8112122-8114443[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 2.6e-06 0.00032 22.3 3.9 1 23 3 26 3 26 0.95 2 20 0.0025 0.31 12.9 0.3 2 23 32 54 31 54 0.95 3 20 2e-05 0.0025 19.5 0.3 2 23 63 85 63 85 0.97 4 20 5.2e-06 0.00064 21.4 1.7 2 23 94 116 93 116 0.95 5 20 0.00013 0.017 16.9 3.7 2 23 124 146 124 146 0.96 6 20 3.9e-06 0.00049 21.7 2.8 2 23 155 177 154 177 0.94 7 20 1e-06 0.00012 23.6 0.8 1 23 183 205 183 205 0.99 8 20 0.079 9.7 8.2 2.2 1 23 249 272 249 272 0.97 9 20 0.0052 0.64 11.9 0.3 1 23 302 325 302 325 0.97 10 20 0.85 1e+02 5.0 0.6 2 21 333 352 332 353 0.92 11 20 0.048 6 8.9 2.1 2 23 362 384 362 384 0.93 12 20 0.014 1.8 10.5 5.7 1 23 407 430 407 430 0.96 13 20 3e-05 0.0037 19.0 0.7 2 23 437 459 436 459 0.96 14 20 3.4e-05 0.0042 18.8 2.2 2 23 466 488 465 488 0.94 15 20 0.0081 0.99 11.3 2.2 1 23 494 517 494 517 0.97 16 20 0.095 12 8.0 5.0 2 23 525 547 525 547 0.95 17 20 0.0019 0.23 13.3 0.3 1 23 554 577 554 577 0.96 18 20 0.0039 0.48 12.3 0.8 1 23 584 607 584 607 0.89 19 20 0.021 2.6 10.0 3.0 3 23 621 642 617 642 0.90 20 20 9.8 1.2e+03 1.6 0.2 2 16 663 677 662 679 0.83
Sequence Information
- Coding Sequence
- ATGGACTATGTTTGCGATTACTGCAGTCGGTCATTCACTCGAAAGTACAATCTGCAGACTCACATCGAGAACTGTCACCTCAACTCGTCATGTTATTGTGATATATGCGAACAAAGATTCGGCAGCCCGGCGGGGCTGCAGCTACACTTGTCCAGAGGACACAATCGATTTGGACAAGGTTTTCCAGAATGCGATCTATGTGGAAGAATCTTTACAAGAAAACAGAATATCACATCGCACATGATTACAGTTCATTTACAAGGCAGTAGGCAAGATATACGCTGCAATTTGTGCAATAAGACCTTCACGACGGATCGTAACTTGAAAAGACATATAAATCAACTTCATAACCCTAACATTGAGTACCCGACATGTGATGATTGTCACAAAGTCTTTAAAGGAAAACACTCTTTGATAGCGCATATACATTCAGCACATAGTCCGGATTATAAAGGCGTTTGCAAGTGCAACTTGTGCGGTAAGGTTTACACTAATAATAGGAATCTGAAGCGACATGTGGAAATGAATCATGGGGAAAGGGGTGAGTTCAAGTGTGAGGTATGTCCTAAAGTGTACACTTCGAATCAGAGTTTACGGCGCCACGCTAGAAGTCATACTGGATATAATTATTCCCAGTTTAATTGTGATCCTAAAACGATTATAGGTAAAGAGAATCTTGACAGCCACATGTTTAGTCATAGAGAGAATTCAAGTTCGAATGAATATGAAGGTAGGTCAAGCCTTTTTCATTGTGAATTTTGTAATAACGCATACGATTTTGAATCTAGATTAAGGTTACACATAAAAACAGATCACTCTTTCCAAGATTTCTATGACTATTGCAAGAAGTCACTGATGAAGACGCGGAAGTCGGAAAAATCGAGGAAACAGAAATTTTTGTTCTTTAACTGTGAATATTGCATCAACGCTTTCGCTACCGTCTACGATTTGAAAGACCACATGAGATCGAACCACGATAAGGAGTACAATTTGTCGACATGCAACGTATGCTTCAGCAAATTCTTTAGCAGAGAAACATTGGTCGAACATAAAAAGATATGTATACCGCCGGAGAACGTCAACTCCTGCAGCCACTGCGACAAACTATTCACGGATATTTCGAGCCTCATCTTTCATACTAAAATCTTTCATCCTCAAGCGCAAATCGCCGATTCTAACATAACATCGAGTTACATTGAAGAATCATTGGAAGCATCCTTTAAATGCCTGCACTGCGATAGGGTATACTACAGCGACCGATCACTCAAACACCACGTCAAGTTGAAACACACAACGGACGAGGCGGTCGAGTGCCAGTACTGCGGAAAgatttgcaataacaaatacTATCTGGCATCGCATATAAAAATCGTCCATACCAATGATTCGTGGTCTAAATGCGATTACTGCGATAAGCAATTCAAATCGAAGAGAAACATACGGCGTCATATCGAATACACGCACTTGGGCATGCAGAGATACAAGTGCATTGAATGTGAAACATTGTTCAAAGAAAAAAGGAGCTTACGTAAGCATGTCAGGACGAAACATCCGAATTCGACAGTGTTCCCTCAATGCCATATCTGTCAAAAACGCTTCGAATCGGCGAAATCTTGTAAGATACATTTAAAACTACTTCACTCATTCAATATGAACACACACCCTTGTGATCTGTGCTCGGTCTCATTTACATCGATAGAAGCGTTAAACATACATTTGTCTACGAAGCATTTAGCTGAGGACGAAATTTACAAATGCGAAGATTGCAATATGGTATTTAAAGGGCAAGAAAGTTTCGACCAACATAATGAAAATTACCACGTGAACATACCGACTTTAAAACAGAACTGCCTACCCCGTTGTATTATATGCATGAAAGATTTTAGTACCCGAAAGACACTAAAGAGACATATAAAAAAGTTCCATTGTGAATTTAATGTCGATGAATTAGCCATATATGGTTCGAAGAAGAGAATATTCCACGTAGAATGCGTGGACTGTCTCAAAAATTTCAATGatgagttttattttaatgtctACCAAAAGTTGAAGCATATTCGAGATTCGATAATATTCAAATGTGAAACGTGCAAGAATTCATATTCCTGTTTGGAGTACGCCATAATGAGGTATAAGCAAACTTTTGATGTGTCCAAAAGTAAGTTATATTTGAGCGAGCTCTGTACGGCTGAAATGAGCGATGGTGGAGGAGATTCTAATGAAATAATGGAACCGGAGAGTACAACGAGTGAAATAAAACTAGAATCTCAAGATCAAATCATGTCTGAGTATTGTATTAAGATGGAACCAATGTCGCCATGA
- Protein Sequence
- MDYVCDYCSRSFTRKYNLQTHIENCHLNSSCYCDICEQRFGSPAGLQLHLSRGHNRFGQGFPECDLCGRIFTRKQNITSHMITVHLQGSRQDIRCNLCNKTFTTDRNLKRHINQLHNPNIEYPTCDDCHKVFKGKHSLIAHIHSAHSPDYKGVCKCNLCGKVYTNNRNLKRHVEMNHGERGEFKCEVCPKVYTSNQSLRRHARSHTGYNYSQFNCDPKTIIGKENLDSHMFSHRENSSSNEYEGRSSLFHCEFCNNAYDFESRLRLHIKTDHSFQDFYDYCKKSLMKTRKSEKSRKQKFLFFNCEYCINAFATVYDLKDHMRSNHDKEYNLSTCNVCFSKFFSRETLVEHKKICIPPENVNSCSHCDKLFTDISSLIFHTKIFHPQAQIADSNITSSYIEESLEASFKCLHCDRVYYSDRSLKHHVKLKHTTDEAVECQYCGKICNNKYYLASHIKIVHTNDSWSKCDYCDKQFKSKRNIRRHIEYTHLGMQRYKCIECETLFKEKRSLRKHVRTKHPNSTVFPQCHICQKRFESAKSCKIHLKLLHSFNMNTHPCDLCSVSFTSIEALNIHLSTKHLAEDEIYKCEDCNMVFKGQESFDQHNENYHVNIPTLKQNCLPRCIICMKDFSTRKTLKRHIKKFHCEFNVDELAIYGSKKRIFHVECVDCLKNFNDEFYFNVYQKLKHIRDSIIFKCETCKNSYSCLEYAIMRYKQTFDVSKSKLYLSELCTAEMSDGGGDSNEIMEPESTTSEIKLESQDQIMSEYCIKMEPMSP*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00824942;
- 90% Identity
- iTF_00985357; iTF_00695884;
- 80% Identity
- -