Basic Information

Insect: Megachile rotundata
Gene Symbol: znf423_1
Assembly: GCA_000220905.1
Location: NW:159914-172651[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 6.2e-06 0.00038 20.0 1.5 1 23 92 114 92 114 0.98

2 22 0.35 22 5.0 3.9 1 23 120 142 120 142 0.97

3 22 7.6e-07 4.7e-05 22.8 4.3 1 23 148 170 148 170 0.99

4 22 0.00016 0.01 15.5 0.2 1 23 176 198 176 198 0.99

5 22 0.0099 0.61 9.9 0.2 1 23 356 379 356 379 0.95

6 22 0.11 6.8 6.6 0.1 2 23 391 413 390 413 0.88

7 22 0.15 9.3 6.1 0.1 3 23 472 492 471 492 0.97

8 22 0.0012 0.077 12.7 0.4 1 23 504 526 504 526 0.96

9 22 0.18 11 5.9 0.1 1 23 535 558 535 558 0.91

10 22 2 1.2e+02 2.6 0.2 1 23 563 586 563 586 0.91

11 22 2.4 1.5e+02 2.4 0.2 10 23 619 633 617 633 0.94

12 22 0.85 52 3.8 0.4 2 23 664 685 664 685 0.96

13 22 0.0073 0.45 10.3 0.0 1 23 690 713 690 713 0.95

14 22 4.7 2.9e+02 1.4 0.1 2 23 778 801 777 801 0.80

15 22 0.00031 0.019 14.6 0.9 2 23 818 840 817 840 0.96

16 22 0.021 1.3 8.8 0.9 1 23 849 872 849 872 0.93

17 22 0.85 53 3.8 0.9 2 23 880 901 879 901 0.95

18 22 0.0025 0.16 11.7 0.1 2 23 1066 1088 1065 1088 0.94

19 22 0.02 1.3 8.9 0.7 1 23 1098 1121 1098 1121 0.96

20 22 0.92 57 3.7 0.4 2 23 1134 1155 1133 1155 0.94

21 22 0.35 22 5.0 0.1 2 23 1164 1186 1163 1186 0.93

22 22 0.57 35 4.3 2.4 1 23 1193 1216 1193 1216 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	6.2e-06	0.00038	20.0	1.5	1	23	92	114	92	114	0.98
2	22	0.35	22	5.0	3.9	1	23	120	142	120	142	0.97
3	22	7.6e-07	4.7e-05	22.8	4.3	1	23	148	170	148	170	0.99
4	22	0.00016	0.01	15.5	0.2	1	23	176	198	176	198	0.99
5	22	0.0099	0.61	9.9	0.2	1	23	356	379	356	379	0.95
6	22	0.11	6.8	6.6	0.1	2	23	391	413	390	413	0.88
7	22	0.15	9.3	6.1	0.1	3	23	472	492	471	492	0.97
8	22	0.0012	0.077	12.7	0.4	1	23	504	526	504	526	0.96
9	22	0.18	11	5.9	0.1	1	23	535	558	535	558	0.91
10	22	2	1.2e+02	2.6	0.2	1	23	563	586	563	586	0.91
11	22	2.4	1.5e+02	2.4	0.2	10	23	619	633	617	633	0.94
12	22	0.85	52	3.8	0.4	2	23	664	685	664	685	0.96
13	22	0.0073	0.45	10.3	0.0	1	23	690	713	690	713	0.95
14	22	4.7	2.9e+02	1.4	0.1	2	23	778	801	777	801	0.80
15	22	0.00031	0.019	14.6	0.9	2	23	818	840	817	840	0.96
16	22	0.021	1.3	8.8	0.9	1	23	849	872	849	872	0.93
17	22	0.85	53	3.8	0.9	2	23	880	901	879	901	0.95
18	22	0.0025	0.16	11.7	0.1	2	23	1066	1088	1065	1088	0.94
19	22	0.02	1.3	8.9	0.7	1	23	1098	1121	1098	1121	0.96
20	22	0.92	57	3.7	0.4	2	23	1134	1155	1133	1155	0.94
21	22	0.35	22	5.0	0.1	2	23	1164	1186	1163	1186	0.93
22	22	0.57	35	4.3	2.4	1	23	1193	1216	1193	1216	0.96

Sequence Information

Coding Sequence: ATGTTGTTCAAGGGTAACAGTTCGAGACTGGAATTGTTGATAGGGAAAATCCAGGCTCACAAGGAACCTTCCCAAGACGATCAACACAAATCAAAAGAAGTGTTGGGGACCGGCAGTTCGTCGTGGCAAAGCGAGGATGCCGGAGCGAACTCGCGACGCGGAGGAGAGACGCCGTCGTCTTGCGCGACACCAACGTCGGTCAGCTTTCCGTCGGAGCCCGAAGTCGACGCCGACGTCGCCGCGAACGCCGATGGAAACAACGCGAACGCGCCTTATCCTTGTCAGTTTTGCGATCGCACCTTTCCACGACTAAGTTACTTGAAAAAACACGAACAGAGTCACGGCGATCAGATGCCTTACAGATGCAGTTGGTGCGCCAGACTGTTCAAGCATAAACGCAGCAGAGATCGACACGTGAAACTTCATACCGGCGACCGAAGATATCGATGCACGCACTGCGAAGCTGCTTTCTCCAGGAGCGATCACCTCAAGATCCACATGAAAACGCACGATACCCAGAAGCCCTACCAGTGTACGGCCTGTTCGAGAGGTTACAATACAGCGGCAGCCTTGACATCCCATATGCAATCGCACAAGAAGCATCATCAGTCCCAGGGAACGAAGAAATTGCAACCGCAAGAGGCGGATCACGGACGAAGGAGCGTCTCCTCGCACAGTACGTCCTCGCCTCCGGTAGCGAGTTCTCCGTCGCCGTCCTTGAACCTTGCTCCGAATCCAAAGTCCGGATTGAAAAGCTCTCAGGGTAGCTGCTCGACCACCCCGATCTTAACCTCTCCTCTCAAGTTGGCCTGCATGTACTGTACCAGAGACTCGTTCAGCTGCATGCAGCAGCTTCAGATGCACGTGCACACGATGCATCGCGCGATCCTGAACGGCGAGAGCGTCGCGACCGTTTCCCCGTCGGGCAACGGAAGCGGCGAGCAACTGGTCGGTTATCACCGCGCGGACAAATCGTCCTCGGAGCGGCTCGAGGGATCCGGCACGTCCGCGGATCACGAAAGAAAGCGCGGCACGACGGAGAAGGAGCAGTACGAAAACGGTCCGTTCGCGTGCAATCGATGCACGATCAAGTTTTCCGCGTTGGCCTCGTTAAGGGATCATCTCCTCTCCATACACGGAATCGACCAATACGGCTCGGCTGCGTTGATGATGTGCCCGTTGTGCGGCATCCCGTGCACCTCCGCGGCCGCGTACGCGGAACACTACGTTCTGCGACACTGCGAAAATCGACGACCGTTGGAGGCTCGCGATTACCCGGAGACCGAGTTGAACGGCGGCTACGACTCGAACACCGGCAGGAGTCAGAAGCGCAGAGAACAAACACCGACCGAGCCGGCCGATCTGACCAACAAACACGCGACCGAGACCAGTTACACGGCTGGAACTCTGCTTTGCGGTCAGTGCGGCGCGGCTCTCAAGGACTTCGAGTCGTTCAGGGAACACCTGGCCAGACATCTCCAAGCCGATCACCGAAACGACCTCAGGCAGCATCCTTGCCCAAAGTGCGACGCCACTTTTCAGGACAAGGAGGACATGCTGGTCCATCTGACCAACCATTACCTAGGCCAGGTCAGCAAGGAGTACGCCTGCGGCGCCTGCAACAACCTCTATCCTCATCCCGATCTTCTGCAGAGACATCTGCTCGACAGCCACGCTCATCATCTCTACAGATGCGCCCTGTGCAGGGACACCTTCGACACCAGGGTTGCGATACAGGTTCACTTCGCGGTGAAACACAGTCAGGAGTGCCGAGTCTATCGGTGCAACGCCTGTTCGACCGTTCCCGACCTAGACAATTCGCCCGGAAACACGACCGGGGAGGGAAAGAGTTTCTTCAGAAGCGAATCCGAGATGGCCAACCACGTGAGAACCGTTCACGCGCCGGCCACGCTCTCCGCCGGCAGTCCTCTCGCTACCAGTCCAGCTTCGACTCCTGGAATCACCGCCGCTGCCGCCTCCTCGGGACCCAGATGCGTTTTCTGCGGGATTTTCTGCGGATCCGAACTCGAGCTCCAACTTCACTTGGCCAGCCATTCCGCTAGCCTCTACAGATGTCCAGTCTGCAGAGAGGGTTTCGCGGTCGAGTTCTTGCTCGACAGGCACATCGCCCAGGCGCATCGTTCCGGCGATCATCGAGCCACGACGAGGACCGCGTCCAGGGAAAACGGACGAATCGGCAGAAGCTCGAGATTGCAGGAAGAGAGTAAATCGCAGAAAAGAGGTCGTTCCCCGGCATCGAGCAACAACAACCTTCCGAACCAACGCGACAATAACAACAAACGCGCCAACTACGTCGGGCCAGCCTCCCAGCAGTGCGATCTATGCGAGAGAGGAGAGTTCGCGAACGATGCGGAACTTCAGGCTCACAAAAAGGTCGCTCACAGCCCTGCTGGGAAACTGCAGAACAAATCGTTGTCGAATCTCAGCATGAGCTGCGCCTATTGCGGAGAGGCGTGCCGATCTCGAACCGAGCTGGAATCTCACACCAGAATCCAGCACGCTTCGAACGAACCCGGAGGACGTCACAAGTGCAACATCTGCGACGAGGTCTGCCCGTCCGGGGCCAGTCTCGCCGAGCACAAGTTGCAGAAACACTGCAAGATTCGACTGAGCGACAGCTGCGTCGTCTGTCGCGGATGCTTGACTTCGGAATCGCAGTTCCTCGAACACGTGCAAAGGCACAGCCTCGAGAACGTGGATCCTCAGCAACGGCACGACGCTTCTCTTCCCCATTTACCCGCGGCCTGCGTCGTTTGCAGACAAACGCTCATCACCGATCTCGAGTGTCGTCTTCACGCCAGACACCATCTCCGAGGTTCCGCCGGATCCCGCAGCCTCGGATCCAGTCCCAATCCTAGCCAGAAGCCGATCCAGAACCCGATCCAGAACCCGAGCTGCTGTCTCTGTCTGAGAGATTACCACGTGGACGAGTTGGTCAGTCTGCCTCCGAGCCACGTGACCGGAGGAGGACAGTCCCTGAGGGTCTGCAAGTCCTGTTACGTTCGTCACTCGCAAGGCCTGCCTATTCTGAATTCGCCTTACGAACCGACCAGGTTAAAATGGTCGTCGAGCAGCAAGGAACCGCCTCGAGGAGGAGAGGGCTCGAGAGACAAATGGGAAACGGACCGTAGAAACAACACCGAGGACAAAACGGACCGAACGAACGACGGTATTAGATGCGACGAGTGCGGCCTCAAGTTCGAGGACTCCGAACAAGCGGAGAAACACAAAATGCTCGAGCACGACAAGATCGGAGCTGCTTCGAACACCTACACCTGTATACAGTGTCAGATGTCCTTTTCGACCGAGGCCAAGATACAGCAACACGTGAGAAAGGATCACCTCGAGTCGTCCGGGAAAACTTCCGTGGATGCTCTCAGGTGTCATTTGTGTCTGTTCGAGGCCAGCAGTCCGTTACAGTTACAGAGTCATTTGATAGAGCACACATTCGCCGGATGCGCCGCTCTCAGCTGCTACATTTGTCAATCTCTCTTCACTGCGCCAATCGGTCTTCAGAATCACATGCTGCAAGAACACGGTTTAGGTGCCCGCCCGTACGACTGTTCCAAGTGTCTCCTCAAGTTCTTCTTCAGAGCCGAGTTGGACCATCACGCGTTAACGTTCCATCGACCCGGAGACGCAACCGAAACCCTGCAGAACGCCAACGAAACGAAAAGGGACGCCGCTGCTACTGATGCTGTTGCTGTTGACcagcaaaattgcaaagagGAGATGATCACGGTAAAAGAGGAGCTACTCGCGGAAGCTGCGGAGGAAGACGAGGAAGAAATCAACGTGGAAGAGCAAGCGGAGCAGGACGCCTCGGGAACGTTCAAACGATCGGACGCggatcaaaaatttaaaacggAGATAGAGAGCGTCGATTCCGTTCAAGAGAAAATTCATTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQDDQHKSKEVLGTGSSSWQSEDAGANSRRGGETPSSCATPTSVSFPSEPEVDADVAANADGNNANAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSQGTKKLQPQEADHGRRSVSSHSTSSPPVASSPSPSLNLAPNPKSGLKSSQGSCSTTPILTSPLKLACMYCTRDSFSCMQQLQMHVHTMHRAILNGESVATVSPSGNGSGEQLVGYHRADKSSSERLEGSGTSADHERKRGTTEKEQYENGPFACNRCTIKFSALASLRDHLLSIHGIDQYGSAALMMCPLCGIPCTSAAAYAEHYVLRHCENRRPLEARDYPETELNGGYDSNTGRSQKRREQTPTEPADLTNKHATETSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDLRQHPCPKCDATFQDKEDMLVHLTNHYLGQVSKEYACGACNNLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDTRVAIQVHFAVKHSQECRVYRCNACSTVPDLDNSPGNTTGEGKSFFRSESEMANHVRTVHAPATLSAGSPLATSPASTPGITAAAASSGPRCVFCGIFCGSELELQLHLASHSASLYRCPVCREGFAVEFLLDRHIAQAHRSGDHRATTRTASRENGRIGRSSRLQEESKSQKRGRSPASSNNNLPNQRDNNNKRANYVGPASQQCDLCERGEFANDAELQAHKKVAHSPAGKLQNKSLSNLSMSCAYCGEACRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGASLAEHKLQKHCKIRLSDSCVVCRGCLTSESQFLEHVQRHSLENVDPQQRHDASLPHLPAACVVCRQTLITDLECRLHARHHLRGSAGSRSLGSSPNPSQKPIQNPIQNPSCCLCLRDYHVDELVSLPPSHVTGGGQSLRVCKSCYVRHSQGLPILNSPYEPTRLKWSSSSKEPPRGGEGSRDKWETDRRNNTEDKTDRTNDGIRCDECGLKFEDSEQAEKHKMLEHDKIGAASNTYTCIQCQMSFSTEAKIQQHVRKDHLESSGKTSVDALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCLLKFFFRAELDHHALTFHRPGDATETLQNANETKRDAAATDAVAVDQQNCKEEMITVKEELLAEAAEEDEEEINVEEQAEQDASGTFKRSDADQKFKTEIESVDSVQEKIHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963393;
90% Identity: iTF_00962708; iTF_00963393; iTF_00962018; iTF_00964654;
80% Identity: -