Basic Information

Insect: Megachile willughbiella
Gene Symbol: Znf423
Assembly: GCA_945859635.1
Location: CAMAOE010000083.1:656553-666274[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 7e-06 0.00092 19.9 1.5 1 23 92 114 92 114 0.98

2 22 0.4 52 5.0 3.9 1 23 120 142 120 142 0.97

3 22 8.7e-07 0.00011 22.8 4.3 1 23 148 170 148 170 0.99

4 22 0.00019 0.024 15.4 0.2 1 23 176 198 176 198 0.99

5 22 0.011 1.5 9.8 0.2 1 23 359 382 359 382 0.95

6 22 0.13 17 6.5 0.1 2 23 394 416 393 416 0.88

7 22 0.17 23 6.1 0.1 3 23 481 501 480 501 0.97

8 22 0.0029 0.37 11.7 0.2 1 23 513 535 513 535 0.96

9 22 0.21 27 5.8 0.1 1 23 544 567 544 567 0.91

10 22 2.2 2.9e+02 2.6 0.2 1 23 572 595 572 595 0.91

11 22 3.9 5.1e+02 1.8 0.2 10 23 629 643 627 643 0.94

12 22 0.97 1.3e+02 3.8 0.4 2 23 685 706 685 706 0.96

13 22 0.0083 1.1 10.3 0.0 1 23 711 734 711 734 0.95

14 22 1.5 1.9e+02 3.2 0.0 2 23 799 822 798 822 0.83

15 22 0.00023 0.03 15.2 1.4 2 23 840 862 839 862 0.96

16 22 0.024 3.1 8.8 0.9 1 23 871 894 871 894 0.93

17 22 0.65 85 4.3 0.2 2 23 902 923 901 923 0.95

18 22 0.0029 0.37 11.7 0.1 2 23 1086 1108 1085 1108 0.94

19 22 0.023 3 8.9 0.7 1 23 1119 1142 1119 1142 0.96

20 22 1.1 1.4e+02 3.6 0.4 2 23 1155 1176 1154 1176 0.94

21 22 0.4 52 5.0 0.1 2 23 1185 1207 1184 1207 0.93

22 22 0.41 53 5.0 2.1 1 23 1214 1237 1214 1237 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	7e-06	0.00092	19.9	1.5	1	23	92	114	92	114	0.98
2	22	0.4	52	5.0	3.9	1	23	120	142	120	142	0.97
3	22	8.7e-07	0.00011	22.8	4.3	1	23	148	170	148	170	0.99
4	22	0.00019	0.024	15.4	0.2	1	23	176	198	176	198	0.99
5	22	0.011	1.5	9.8	0.2	1	23	359	382	359	382	0.95
6	22	0.13	17	6.5	0.1	2	23	394	416	393	416	0.88
7	22	0.17	23	6.1	0.1	3	23	481	501	480	501	0.97
8	22	0.0029	0.37	11.7	0.2	1	23	513	535	513	535	0.96
9	22	0.21	27	5.8	0.1	1	23	544	567	544	567	0.91
10	22	2.2	2.9e+02	2.6	0.2	1	23	572	595	572	595	0.91
11	22	3.9	5.1e+02	1.8	0.2	10	23	629	643	627	643	0.94
12	22	0.97	1.3e+02	3.8	0.4	2	23	685	706	685	706	0.96
13	22	0.0083	1.1	10.3	0.0	1	23	711	734	711	734	0.95
14	22	1.5	1.9e+02	3.2	0.0	2	23	799	822	798	822	0.83
15	22	0.00023	0.03	15.2	1.4	2	23	840	862	839	862	0.96
16	22	0.024	3.1	8.8	0.9	1	23	871	894	871	894	0.93
17	22	0.65	85	4.3	0.2	2	23	902	923	901	923	0.95
18	22	0.0029	0.37	11.7	0.1	2	23	1086	1108	1085	1108	0.94
19	22	0.023	3	8.9	0.7	1	23	1119	1142	1119	1142	0.96
20	22	1.1	1.4e+02	3.6	0.4	2	23	1155	1176	1154	1176	0.94
21	22	0.4	52	5.0	0.1	2	23	1185	1207	1184	1207	0.93
22	22	0.41	53	5.0	2.1	1	23	1214	1237	1214	1237	0.96

Sequence Information

Coding Sequence: ATGTTGTTCAAAGGTAACAGTTCGAGACTGGAATTGTTGATAGGGAAAATCCAGGCCCACAAGGAACCCTCCCAAGACGATCAACAGAAATCTAAAGAAGTGTTGGGGACCGGCAGTTCGTCGTGGCAAAGCGAGGATGCCGGAGCGAACTCGCGGCGCGGAGGAGAGACGCCGTCGTCTTGCGCGACGCCAACGTCTGTCAGCTTTCCGTCGGAGCCCGAAGTCGACGCCGACGTCGCCGCGAACGCCGATGGAAACCTGGCGAACGCGCCTTATCCTTGTCAGTTTTGCGATCGCACCTTTCCACGACTAAGTTACTTGAAAAAACACGAACAGAGTCACGGCGATCAGATGCCTTACAGATGCAGTTGGTGCGCCAGACTGTTCAAGCATAAACGCAGCAGAGATCGACACGTGAAACTTCATACCGGCGACCGAAGATATCGATGCACGCACTGCGAAGCTGCTTTCTCCAGGAGCGATCACCTCAAGATCCACATGAAAACGCACGATACTCAGAAGCCCTATCAGTGTACCGCCTGTTCGAGAGGTTACAATACAGCGGCAGCCTTGACGTCCCACATGCAGTCGCACAAGAAGCACCATCAGTCCCAGGGAACGAACAAATTGCAACCGCAAGAGGCGGAACACGGACGAAGGAGCGTCTCCTCGCACAGTACGTCCTCGCCTCCGGTAGCGAGTTCTCCGTCGCCATCCTTGAACCTCGGCCCGAATCCAAAGTCCGGATTGAAAAGCACTCAGGGTAGTTGCTCGACCACCCCGATCTTAACCTCTCCTCTCAAGTTGGCCTGCATGTACTGTACCAGGGACTCGTTCAGCTGCATGCAGCAGCTTCAGATGCACGTGCACACGATGCATCGCGCGATCCTGAACGGCGAGAGCGTCGCGACGGTTTCCCCGTCGGGCAACGGAAGCACCGAGCCGCTCGTAGGTTATCACCGCGCGGACAAATCGTCCTCGGAGCGGCTCGAGGGATCCGGCTCGTCCGTCCAACAGCCGGATCACGAAAGGAAGCGCGGCACCACGGAGAACGAACAGTACGAAAACGGTCCGTTCGCGTGTAATCGGTGCACGATCAAGTTTTCCGCGTTGGCCTCGTTAAGGGATCATCTCCTGTCCATCCACGGAATCGACCAATACGGCTCGGCTGCCTTGATGATGTGCCCGTTATGCGGCATCCCTTGCACCTCCGCGGCCGCGTACGCGGAACACTACGTTCTGCGGCACTGCGAGAATCGACGGCCGAACCTCCCGCTGGAGGCTCTCCCGAGGAGAGATTACCCGGAGACCGAATTGAACGGTGGCTACGACTCGAACACCGCCAGGAACCAGAAGCGCAGAGAACAAACCCCGACCGAACCGGCCGATCTGACCAACAAACACGCGACCGAGACCAGTTACACGGCTGGGACTCTGCTTTGCGGTCAGTGCGGCGCGGCTCTGAAAGACTTCGAGTCGTTCAGGGAACACCTAGCCAGACATCTTCAAGCCGACCATCGAAACGACCTCAGGCAGCATCCTTGCCCAAAGTGCGACGCCGCTTTTCAGGACAAGGAGGACATGCTTGTGCACCTGACCAACCACTACCTAGGCCAGGTCAGCAAGGAGTACGCCTGCGGCGCTTGCAACAACCTCTATCCTCATCCTGACCTTCTGCAGAGACATCTGCTCGACAGCCACGCTCATCATCTCTACAGATGTGCCTTGTGCAGGGACACCTTCGACACCAGGGTAGCGATACAGGTTCACTTCGCGGTGAAACACAGTCAGGAGTGCCGAGTCTATCGGTGCAACGCCTGCTCGGCCGTTCCCGACACCTTGGACAATTCGCCCGGGAACGCGACCGGCGAGGGAAAGAGTTTCTTCAGAAGCGAATCCGAGATGGCCAGCCACGTGAGAACCGTTCACGCGCCGGCCACGCTCAACGCCGGCAGCCCTCTCGCTAGCAGTCCAGCCTCTACTCCTGGGATCACCGGCGCCGCCGCTGTAGCCGCCACCGTCGCCGCCACCGTCGCCTCCTCCTCAGGACCCAGGTGCGTTTTCTGCGGAATCTTCTGCGGATCGGAGCTCGAGCTCCAACTTCACTTGGCCAGCCATTCCGCCAGCCTCTACAGATGTCCAGTCTGCAGAGAGGGTTTCGCCGTCGAGTTCTTGCTCGACAGGCACATCGCCCAGGCGCATCGTTCCGGCGATCATCGAGCCACCTCGAGAACCGCGTCCAGGGAAAACGGACGAATCGCCAGAACCTCGAGATTGCAGGAAGAGAGTAAATCCCAGAAAAGGGGTCGTTCGCCGGCATCGAGCAACAACAACCTTCCGAACCAACGGGACAACAACAACAAACGCGCCAACTACGTCGGGCCAGCCTCCCAGCAATGCGATCTCTGCGAGAGAGGAGAGTTCGCGAACGAAGCGGAACTTCAGGCCCACAAAAAGGTCGCTCACAGCCCTGCCGGTGGCAAACTGCAGAACAAATCGTTGGCGAATCTCAGCATGAGCTGCGCCTACTGCGGAGAGACGTGCCGGTCTCGAACCGAGCTGGAATCTCACACCAGAATCCAGCACGCTTCGAACGAGCCTGGAGGACGTCACAAGTGCAACATCTGCGACGAGGTCTGCCCCTCCGGAGCCAGTCTCGCCGAGCACAAGCTGCAGAAACACTGCAAGATCCGGCTGAGCGACAGCTGCGTCGTCTGTCGCGGAAGCTTGACTTCGGAATCGCAGTTCCTCGAACACGTGCAAAGGCACAGCCTCGAGAACGTCGATCCTCAGCAACGGCACGACGCTTCTCTTCCGCATTTGCCCGCGGCCTGCGTCGTTTGCAGACAAACGCTCATCACCGATCTCGAGTGTCGTCTTCACGCCAGACATCATCTCCGAGCTTCCGTCGGATCTCGCAGCCTCGGATCCAGTCCCAATCCCAGCCAGAAGCCGCCGATCCAGAACCCGAGCTGCTGTCTCTGTCTGAGGGATTACCACGTGGACGAGTTGGTCAGTCTGCCTCCGAGCCACGTGACCGGAGGAGGACAGTCCCTCAGGGTCTGCAAGTCTTGCTACGTTCGTCACTCGCAAGGTCTGCCCATACTGAACTCGCCTTACGAACCGACCAGGTTAAAATGGACGTCGAGCAAGGAACCGTCTCGAGGAGAAGCGTCGACGGACAAATGGGAAACGGACCGTACAAACAACACCGAGGAGAAAACGGACCGAACGAACAACGGACCGGACGGTATTAGATGCGACGAGTGCGGCCTCAAGTTCGAGGATTCCGAACAAGCGGAGAAACACAAAATGCTCGAGCACGACAAGATTGTTGGAGCTACTTCGAACACCTACACCTGTATACAGTGTCAGATGTCTTTTTCGACCGAGGCCAAGATACAGCAACACGTGAGAAAAGATCACCTGGAGTCGTCCGGGAAAGCTTCCGTGGATGCTCTCAGGTGCCATTTGTGTCTGTTCGAGGCCACCAGTCCGTTACAGTTACAGAGTCATTTGATAGAGCACACTTTTGCCGGATGCGCCGCTCTCAGCTGTTACATTTGTCAGTCTCTCTTCACTGCGCCCATCGGTCTTCAGAATCACATGCTACAAGAACACGGTTTAGGTGCCCGTCCGTACGACTGTTCCAAGTGCGTCCTCAAGTTCTTCTTCAGAGCCGAGTTGGACCATCACGCTCTAACGTTCCATCGAGCCGGAGATGCAACCGAAACCGTGCAGAACGCCAACGAAACGAAAAGGGACGCTGCTGCAGCTGCTGTTGCTGCCGAACAACAAAATTGCAAAGAGGAAATGATCACGGTAAAAGAAGAGCTACTCGCGGAAGCTGCGGAGGAAGACGACGAGGAAGAAATCAACGTGGAAGAGCAAGTGGAACAGGACGCCTCGGGAACGTTCAAACGATCGGACGCGGATCAAAAATTTAAAACAGAGATAGAGAATGATTCCGTTCACGAAAAGATTCATTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQDDQQKSKEVLGTGSSSWQSEDAGANSRRGGETPSSCATPTSVSFPSEPEVDADVAANADGNLANAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSQGTNKLQPQEAEHGRRSVSSHSTSSPPVASSPSPSLNLGPNPKSGLKSTQGSCSTTPILTSPLKLACMYCTRDSFSCMQQLQMHVHTMHRAILNGESVATVSPSGNGSTEPLVGYHRADKSSSERLEGSGSSVQQPDHERKRGTTENEQYENGPFACNRCTIKFSALASLRDHLLSIHGIDQYGSAALMMCPLCGIPCTSAAAYAEHYVLRHCENRRPNLPLEALPRRDYPETELNGGYDSNTARNQKRREQTPTEPADLTNKHATETSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDLRQHPCPKCDAAFQDKEDMLVHLTNHYLGQVSKEYACGACNNLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDTRVAIQVHFAVKHSQECRVYRCNACSAVPDTLDNSPGNATGEGKSFFRSESEMASHVRTVHAPATLNAGSPLASSPASTPGITGAAAVAATVAATVASSSGPRCVFCGIFCGSELELQLHLASHSASLYRCPVCREGFAVEFLLDRHIAQAHRSGDHRATSRTASRENGRIARTSRLQEESKSQKRGRSPASSNNNLPNQRDNNNKRANYVGPASQQCDLCERGEFANEAELQAHKKVAHSPAGGKLQNKSLANLSMSCAYCGETCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGASLAEHKLQKHCKIRLSDSCVVCRGSLTSESQFLEHVQRHSLENVDPQQRHDASLPHLPAACVVCRQTLITDLECRLHARHHLRASVGSRSLGSSPNPSQKPPIQNPSCCLCLRDYHVDELVSLPPSHVTGGGQSLRVCKSCYVRHSQGLPILNSPYEPTRLKWTSSKEPSRGEASTDKWETDRTNNTEEKTDRTNNGPDGIRCDECGLKFEDSEQAEKHKMLEHDKIVGATSNTYTCIQCQMSFSTEAKIQQHVRKDHLESSGKASVDALRCHLCLFEATSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCVLKFFFRAELDHHALTFHRAGDATETVQNANETKRDAAAAAVAAEQQNCKEEMITVKEELLAEAAEEDDEEEINVEEQVEQDASGTFKRSDADQKFKTEIENDSVHEKIHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963393;
90% Identity: iTF_00964026;
80% Identity: -