Basic Information

Insect: Megachile leachella
Gene Symbol: znf423
Assembly: GCA_963576845.1
Location: OY756249.1:153782-163028[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 8.9e-06 0.0013 20.0 1.5 1 23 92 114 92 114 0.98

2 22 0.51 76 5.0 3.9 1 23 120 142 120 142 0.97

3 22 1.1e-06 0.00016 22.8 4.3 1 23 148 170 148 170 0.99

4 22 0.00024 0.035 15.5 0.2 1 23 176 198 176 198 0.99

5 22 0.014 2.1 9.9 0.2 1 23 356 379 356 379 0.95

6 22 0.16 24 6.6 0.1 2 23 391 413 390 413 0.88

7 22 0.22 33 6.1 0.1 3 23 472 492 471 492 0.97

8 22 0.0018 0.27 12.7 0.4 1 23 504 526 504 526 0.96

9 22 0.27 40 5.9 0.1 1 23 535 558 535 558 0.91

10 22 2.8 4.2e+02 2.6 0.2 1 23 563 586 563 586 0.91

11 22 5 7.5e+02 1.9 0.2 10 23 619 633 617 633 0.94

12 22 1.2 1.8e+02 3.8 0.4 2 23 664 685 664 685 0.96

13 22 0.011 1.6 10.3 0.0 1 23 690 713 690 713 0.95

14 22 6.8 1e+03 1.5 0.1 2 23 778 801 777 801 0.80

15 22 0.00029 0.044 15.2 1.4 2 23 818 840 817 840 0.96

16 22 0.03 4.6 8.8 0.9 1 23 849 872 849 872 0.93

17 22 3 4.5e+02 2.6 0.2 2 23 880 901 879 901 0.94

18 22 0.0036 0.54 11.7 0.1 2 23 1061 1083 1060 1083 0.94

19 22 0.029 4.4 8.9 0.7 1 23 1093 1116 1093 1116 0.96

20 22 1.3 2e+02 3.7 0.4 2 23 1129 1150 1128 1150 0.94

21 22 0.51 76 5.0 0.1 2 23 1159 1181 1158 1181 0.93

22 22 0.83 1.2e+02 4.3 2.4 1 23 1188 1211 1188 1211 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	8.9e-06	0.0013	20.0	1.5	1	23	92	114	92	114	0.98
2	22	0.51	76	5.0	3.9	1	23	120	142	120	142	0.97
3	22	1.1e-06	0.00016	22.8	4.3	1	23	148	170	148	170	0.99
4	22	0.00024	0.035	15.5	0.2	1	23	176	198	176	198	0.99
5	22	0.014	2.1	9.9	0.2	1	23	356	379	356	379	0.95
6	22	0.16	24	6.6	0.1	2	23	391	413	390	413	0.88
7	22	0.22	33	6.1	0.1	3	23	472	492	471	492	0.97
8	22	0.0018	0.27	12.7	0.4	1	23	504	526	504	526	0.96
9	22	0.27	40	5.9	0.1	1	23	535	558	535	558	0.91
10	22	2.8	4.2e+02	2.6	0.2	1	23	563	586	563	586	0.91
11	22	5	7.5e+02	1.9	0.2	10	23	619	633	617	633	0.94
12	22	1.2	1.8e+02	3.8	0.4	2	23	664	685	664	685	0.96
13	22	0.011	1.6	10.3	0.0	1	23	690	713	690	713	0.95
14	22	6.8	1e+03	1.5	0.1	2	23	778	801	777	801	0.80
15	22	0.00029	0.044	15.2	1.4	2	23	818	840	817	840	0.96
16	22	0.03	4.6	8.8	0.9	1	23	849	872	849	872	0.93
17	22	3	4.5e+02	2.6	0.2	2	23	880	901	879	901	0.94
18	22	0.0036	0.54	11.7	0.1	2	23	1061	1083	1060	1083	0.94
19	22	0.029	4.4	8.9	0.7	1	23	1093	1116	1093	1116	0.96
20	22	1.3	2e+02	3.7	0.4	2	23	1129	1150	1128	1150	0.94
21	22	0.51	76	5.0	0.1	2	23	1159	1181	1158	1181	0.93
22	22	0.83	1.2e+02	4.3	2.4	1	23	1188	1211	1188	1211	0.96

Sequence Information

Coding Sequence: ATGTTGTTCAAGGGTAACAGTTCGAGACTGGAATTGTTGATAGGGAAAATCCAGGCTCACAAGGAACCTTCCCAAGACGATCAACACAAATCAAAAGAAGTTTTGGGGACCGGCAGTTCGTCGTGGCAAAGCGAGGATGCCGGAGCGAACTCGCGACGCGGAGGAGAGACACCGTCGTCTTGCGCGACGCCAACGTCGGTCAGCTTTCCGTCGGAGCCCGAAGTCGACGCCGACGTCGCCGCGAACGCCGATGGAAACAACGCGAACGCGCCTTATCCTTGTCAGTTTTGCGATCGCACCTTTCCACGACTAAGTTATTTGAAAAAACACGAACAGAGTCACGGCGATCAGATGCCTTACAGATGCAGTTGGTGCGCCAGACTGTTCAAGCATAAGCGCAGCAGAGATCGACACGTGAAACTTCATACCGGCGACCGAAGATATCGATGCACGCACTGCGAAGCTGCTTTCTCTAGGAGCGATCACCTCAAGATCCACATGAAAACGCACGATACACAGAAGCCCTACCAGTGTACGGCCTGTTCGAGAGGTTACAATACAGCGGCAGCCTTGACGTCCCATATGCAATCGCACAAGAAGCATCATCAGTCCCAGGGAACGAACAAATTGCAACCGCAAGAGGCGGATCACGGACGAAGGAGCGTCTCCTCGCACAGTACGTCCTCGCCTCCGGTAGCGAGTTCTCCGTCGCCGTCCTTGAACCTTGCTCCGAATCCAAAGTCCGGATTGAAAAGCTCTCAGGGTAGCTGCTCGACCACCCCGATCTTAACCTCTCCTCTCAAATTGGCCTGCATGTACTGTACCAGAGACTCGTTCAGCTGCATGCAGCAGCTTCAGATGCACGTGCACACGATGCATCGCGCGATCCTGAACGGCGAAAGCGTCGCGACCGTTTCACCGTCGGGCAACGGAAGCGGCGAACAATTGGTCAGTTATCATCGCGCGGACAAATCGTCCTCGGAACGGTTCGAGGGATCCGGCGCGTCCGCGGATCACGAAAGAAAACGCGGCACGACGGAGAAGGAGCAGTACGAAAACGGTCCGTTCGCGTGCAATCGATGCACGATCAAGTTTTCCGCGTTGGCCTCGTTAAGGGATCATCTCCTGTCGATACACGGAATCGACCAATACGGCTCGGCTACGTTGATGATGTGCCCGTTGTGCGGCATCCCTTGTACCTCCGCGGCAGCGTACGCGGAACACTACGTTCTGCGACACTGCGAAAATCGACGGCCGCTGGAAGCTCGAGATTACCCGGAGACCGAGTTGAACGGCGGCTACGACTCGAACACTGCCAGGAGTCAGAAGCGAAGAGAACAAACCCCGACCGAACCGGCCGATCTGACCAACAAACACGCGACCGAGACCAGTTACACGGCTGGAACTCTACTTTGCGGTCAGTGCGGCGCGGCTCTCAAGGATTTCGAGTCGTTCAGGGAACATCTGGCCAGACATCTTCAAGCCGACCACCGAAACGACCTCAGGCAGCATCCTTGCCCAAAGTGTGACGCGACTTTTCAAGATAAGGAGGATATGCTGGTGCACCTGACCAACCACTACCTAGGCCAGGTCAGCAAGGAGTACGCCTGCGGCGCCTGCAACAACCTCTATCCTCATCCCGATCTTCTGCAAAGACATTTGCTAGACAGCCACGCTCACCATCTCTACAGATGCGCCCTGTGCAGGGACACCTTCGACACCAGGGTAGCGATACAGGTTCACTTCGCGGTGAAACATAGTCAGGAGTGCCGAATCTATCGGTGCAACGCCTGCTCGACCGTTCCCGACCTAGATAATTCGCCCGGAAACGCGACCGGAGAAGGAAAGAGTTTCTTCAGAAGCGAATCCGAGATGGCCAGCCACGTGAGAACCGTGCACGCGCCGACCACGCTCTCCGCCGGCAGTCCTCTCGCTAACAGTCCAGCTTCTACTCCTGGAATCACCGCCGCTGCCGCCTCCTCGGGACCCAGATGCGTCTTTTGCGGAATTTTCTGCGGATCGGAACTCGAGCTCCAACTTCACTTGGCCAGCCATTCCGCTAGCCTCTACAGATGTCCAGTCTGCAGAGAGGGTTTCGCGGTCGAGTTTTTGCTCGACAGGCACATTGCCCAGGCGCATCGTTCCGGCGATCATCGAGCCACAGCGAGGACCGCGTCCAGGGAAAACGGACGAATCGGCAGAAGCTCGAGATTGCAGGAAGAGAGCAAATCGCAGAAAAGAGGTCGTTCCCCGGCATCGAGTAACAACAACCTTCCGAACCAACGCGACAATAACAACAAACGCGCCAACTACGTCGGTCCAGTCTCCCAGCAGTGCGATCTATGCGAGAGAGGAGAGTTCGCGAACGACGCGGAACTTCAGGCCCACAAAAAGGTCGCTCACAGCCCTGCTGGGAAACTGCAGAACAAATCGCTGTCGAATCTCAGCATGAGCTGCGCCTATTGCGGAGAGACGTGCCGATCTCGAACCGAGCTGGAATCTCACACCAGAATCCAGCACGCTTCGAACGAACCCGGAGGACGTCACAAGTGCAACATCTGCGACGAGGTCTGCCCGTCCGGAGCCAGTCTCGCCGAGCACAAACTGCAGAAACACTGCAAAATCCGACTGAGCGACAGCTGCGTCGTCTGTCGCGGAAACTTGACTTCGGAATCGCAGTTCCTCGAACACGTTCAAAGGCACAGTCTCGAGAACGTCGATCCTCAGCAACGGCACGACGCTTCTCTTCCCCATTTACCCGCGGCCTGCGTCGTTTGCAGACAAACGCTCATCACCGATCTCGAGTGTCGTCTTCACGCCAGACACCATCTCCGAGCTTCCGCCGGATCCCGTAGCCTCGGATCCAGTCCCAATCCTAGCCAGAAGCCGATCCAGAACCCGAGCTGCTGTCTCTGTCTGAGGGATTACCACGTGGACGAGTTGGTCAGTCTGCCTCCGAGCCACGTGACCGGAGGAGGACAGTCCCTCAGGGTCTGCAAGTCTTGCTACGTTCGTCACTCGCAAGGTCTGCCTATTCTGAACTCGCCTTACGAACCGACCAGGTTAAAATGGTCGTCGAGTAGCAAGGAACCGCCTCGAGGAGAAGGCTCCAGGGATAAATGGGAAACGGATCGTACAAACAACACCGAGGATAAAACGGACCGAACGAACGACGGTATTAGATGCGACGAGTGCGGGCTCAAGTTCGAGGACTCCGAACAAGCGGAGAAACACAAAATGCTCGAGCACGACAAGATCGGTGCTGCTTCGAACACCTACACCTGTATACAGTGTCAGATGTCTTTTTCGACCGAGGCCAAGATACAGCAACACGTGAGAAAGGATCACCTGGAGTCGTCCGGGAAAACTTCCGTCGACGCTCTCAGGTGCCATTTGTGTCTGTTCGAGGCCAGCAGTCCGTTACAGTTACAGAGTCATTTGATAGAGCACACATTTGCCGGATGCGCCGCTCTCAGCTGCTACATTTGTCAGTCTCTCTTCACCGCGCCCATCGGTCTTCAGAATCACATGCTGCAAGAACACGGTTTAGGTGCCCGACCGTACGACTGTTCCAAGTGTCTCCTCAAGTTCTTCTTCAGAGCCGAGTTGGACCATCACGCGTTAACGTTTCATCGACCCGGAGACTCGAGCGAAACCTTGCAGAACACCAACGAAACGAAAAGGGACGCCGCTGCTGCTggtgctgttgttgctgttgttgctgacCAGCAAAATTGCAAAGAAGAGATGATCACGGTAAAAGAGGAACTACTCGCGGAAACTGCGGAGGAAGACGAGGAAGAAATCAACGTGGAAGAGCAAGCGGAGCAGGACGCCTCGGGAACGTTCAAACGATCGGACGCGGATCAAAAGTTTAAAACAGAGATAGAGAGTGATTCCGTTCACGAAAAAATTCATTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQDDQHKSKEVLGTGSSSWQSEDAGANSRRGGETPSSCATPTSVSFPSEPEVDADVAANADGNNANAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSQGTNKLQPQEADHGRRSVSSHSTSSPPVASSPSPSLNLAPNPKSGLKSSQGSCSTTPILTSPLKLACMYCTRDSFSCMQQLQMHVHTMHRAILNGESVATVSPSGNGSGEQLVSYHRADKSSSERFEGSGASADHERKRGTTEKEQYENGPFACNRCTIKFSALASLRDHLLSIHGIDQYGSATLMMCPLCGIPCTSAAAYAEHYVLRHCENRRPLEARDYPETELNGGYDSNTARSQKRREQTPTEPADLTNKHATETSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDLRQHPCPKCDATFQDKEDMLVHLTNHYLGQVSKEYACGACNNLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDTRVAIQVHFAVKHSQECRIYRCNACSTVPDLDNSPGNATGEGKSFFRSESEMASHVRTVHAPTTLSAGSPLANSPASTPGITAAAASSGPRCVFCGIFCGSELELQLHLASHSASLYRCPVCREGFAVEFLLDRHIAQAHRSGDHRATARTASRENGRIGRSSRLQEESKSQKRGRSPASSNNNLPNQRDNNNKRANYVGPVSQQCDLCERGEFANDAELQAHKKVAHSPAGKLQNKSLSNLSMSCAYCGETCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGASLAEHKLQKHCKIRLSDSCVVCRGNLTSESQFLEHVQRHSLENVDPQQRHDASLPHLPAACVVCRQTLITDLECRLHARHHLRASAGSRSLGSSPNPSQKPIQNPSCCLCLRDYHVDELVSLPPSHVTGGGQSLRVCKSCYVRHSQGLPILNSPYEPTRLKWSSSSKEPPRGEGSRDKWETDRTNNTEDKTDRTNDGIRCDECGLKFEDSEQAEKHKMLEHDKIGAASNTYTCIQCQMSFSTEAKIQQHVRKDHLESSGKTSVDALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCLLKFFFRAELDHHALTFHRPGDSSETLQNTNETKRDAAAAGAVVAVVADQQNCKEEMITVKEELLAETAEEDEEEINVEEQAEQDASGTFKRSDADQKFKTEIESDSVHEKIHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963393;
90% Identity: iTF_00964026;
80% Identity: -