Basic Information

Insect: Megachile ligniseca
Gene Symbol: znf423
Assembly: GCA_945859565.1
Location: CAMAOB010000324.1:107919-117372[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 8.5e-06 0.00087 19.9 1.5 1 23 92 114 92 114 0.98

2 22 0.48 50 5.0 3.9 1 23 120 142 120 142 0.97

3 22 1e-06 0.00011 22.8 4.3 1 23 148 170 148 170 0.99

4 22 0.00023 0.023 15.5 0.2 1 23 176 198 176 198 0.99

5 22 0.014 1.4 9.9 0.2 1 23 362 385 362 385 0.95

6 22 1.9 2e+02 3.1 0.1 2 23 397 419 396 419 0.88

7 22 0.21 21 6.1 0.1 3 23 482 502 481 502 0.97

8 22 0.0017 0.18 12.7 0.4 1 23 514 536 514 536 0.96

9 22 0.25 26 5.9 0.1 1 23 545 568 545 568 0.91

10 22 2.7 2.8e+02 2.6 0.2 1 23 573 596 573 596 0.91

11 22 4.7 4.9e+02 1.9 0.2 10 23 629 643 627 643 0.94

12 22 1.2 1.2e+02 3.8 0.4 2 23 684 705 684 705 0.96

13 22 0.01 1 10.3 0.0 1 23 710 733 710 733 0.95

14 22 1.8 1.8e+02 3.2 0.0 2 23 798 821 797 821 0.83

15 22 0.00027 0.028 15.2 1.0 2 23 838 860 837 860 0.96

16 22 0.029 3 8.8 0.9 1 23 869 892 869 892 0.93

17 22 0.79 81 4.3 0.2 2 23 900 921 899 921 0.95

18 22 0.017 1.7 9.6 0.2 2 23 1082 1104 1081 1104 0.89

19 22 0.028 2.9 8.9 0.7 1 23 1114 1137 1114 1137 0.96

20 22 1.3 1.3e+02 3.7 0.4 2 23 1150 1171 1149 1171 0.94

21 22 0.48 50 5.0 0.1 2 23 1180 1202 1179 1202 0.93

22 22 0.49 50 5.0 2.1 1 23 1209 1232 1209 1232 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	8.5e-06	0.00087	19.9	1.5	1	23	92	114	92	114	0.98
2	22	0.48	50	5.0	3.9	1	23	120	142	120	142	0.97
3	22	1e-06	0.00011	22.8	4.3	1	23	148	170	148	170	0.99
4	22	0.00023	0.023	15.5	0.2	1	23	176	198	176	198	0.99
5	22	0.014	1.4	9.9	0.2	1	23	362	385	362	385	0.95
6	22	1.9	2e+02	3.1	0.1	2	23	397	419	396	419	0.88
7	22	0.21	21	6.1	0.1	3	23	482	502	481	502	0.97
8	22	0.0017	0.18	12.7	0.4	1	23	514	536	514	536	0.96
9	22	0.25	26	5.9	0.1	1	23	545	568	545	568	0.91
10	22	2.7	2.8e+02	2.6	0.2	1	23	573	596	573	596	0.91
11	22	4.7	4.9e+02	1.9	0.2	10	23	629	643	627	643	0.94
12	22	1.2	1.2e+02	3.8	0.4	2	23	684	705	684	705	0.96
13	22	0.01	1	10.3	0.0	1	23	710	733	710	733	0.95
14	22	1.8	1.8e+02	3.2	0.0	2	23	798	821	797	821	0.83
15	22	0.00027	0.028	15.2	1.0	2	23	838	860	837	860	0.96
16	22	0.029	3	8.8	0.9	1	23	869	892	869	892	0.93
17	22	0.79	81	4.3	0.2	2	23	900	921	899	921	0.95
18	22	0.017	1.7	9.6	0.2	2	23	1082	1104	1081	1104	0.89
19	22	0.028	2.9	8.9	0.7	1	23	1114	1137	1114	1137	0.96
20	22	1.3	1.3e+02	3.7	0.4	2	23	1150	1171	1149	1171	0.94
21	22	0.48	50	5.0	0.1	2	23	1180	1202	1179	1202	0.93
22	22	0.49	50	5.0	2.1	1	23	1209	1232	1209	1232	0.96

Sequence Information

Coding Sequence: ATGTTGTTCAAGGGTAACAGTTCGAGGCTGGAATTGTTGATAGGGAAAATTCAGGCCCACAAGGAACCTTCCCAAGACGATCAACACAAATCTAAAGAAGTGTTGGGGACCGGCAGTTCGTCGTGGCAAAGCGAGGATGCCGGAGCGAACTCGCGGCGCGGAGGAGAGACACCGTCGTCTTGCGCGACGCCAACGTCGGTCAGCTTTCCGTCGGAGCCCGAAGTCGACGCGGACGTCGCCGCGAACGCCGATGGAAACAACGCGAACGCGCCTTATCCTTGTCAATTTTGCGATCGCACCTTTCCACGACTAAGTTACTTGAAAAAACACGAACAGAGTCACGGTGATCAGATGCCTTACAGATGCAGTTGGTGCGCCAGACTGTTCAAGCATAAACGCAGCAGAGATCGACACGTGAAACTTCATACCGGCGACCGAAGATATCGATGCACGCACTGCGAAGCTGCTTTCTCCAGGAGCGATCACCTCAAGATCCACATGAAAACGCACGATACCCAGAAACCCTACCAGTGTACGGCCTGTTCGAGAGGTTACAATACAGCGGCAGCCTTGACGTCCCACATGCAGTCGCACAAGAAGCACCATCAGTCCCACCAGGGAACGAACAAATTGCAACCGCAAGAGGCGGATCACGGACGAAGGAGCGTCTCCTCGCACAGTACGTCCTCGCCTCCGGTAGCGAGTTCTCCGTCGCCATCCTTGAATCTCGGCCCGAATCCAAAGTCCGGATTGAAAAGCTCTCAGGGTAGTTGCTCGACCACACCGATCTTAACCTCTCCCCTCAAGTTGGCCTGCATGTACTGTACCAGAGACTCGTTCAGCTGCATGCAGCAGCTTCAGATGCACGTGCACACGATGCATCGCGCGATCCTGAACGACGAGAGCGTCGCGACGGTTTCCCCGTCGGGCAACGGAAGCAGCGAACAGCTCGTCGGTTATCACCGCGCGGACAAACCGTCCTCGGAGCGGCTCGAGGGATCCGGCTCGTCCGTTCAAGAGGCCGATCACGAAAGAGAAAGAAAACGCGGCACGACGGAGAAGGACCAGTACGAAAACGGTCCGTTCGCGTGTAATCGGTGCACGATCAAGTTTTCCGCGTTGGCCTCGTTAAGGGATCATCTCCTCTCCATCCACGGAATCGACCAATACGGCTCGGCTGCCTTGATGATGTGTCCGTTGTGCAGCGTTCCTTGCACCTCCGCGGCCGCGTACGCCGAACACTACGTTCTGCGGCACTGCGAGAATCGACGACCGAATCATTCGCTGGAGGCTCGCGATTACCCGGAGACCACCGAATTGAACGGCGGCTACGACTCGAACACCGCCAGGAACCAGAAGCGCAGAGAACAAACCCCGACCGAGCCGGCCGATCTGACCAACAAACACGCGACCGAGACCAGTTACACGGCTGGAACTCTGCTTTGCGGTCAGTGCGGCGCGGCTCTGAAGGACTTTGAGTCGTTCAGGGAACACCTAGCCAGACATCTCCAAGCCGACCATCGAAACGACCTCAGGCAGCATCCTTGCCCAAAGTGCGACGCCACTTTTCAGGACAAGGAGGACATGCTGGTGCACCTGACCAACCACTACCTAGGCCAGGTCAGCAAGGAGTACGCCTGCGGCGCCTGCAACAACCTCTATCCTCATCCCGACCTTCTGCAGAGACATCTGCTCGACAGCCACGCTCATCATCTCTACAGGTGTGCCCTGTGCAGGGACACCTTCGACACCAGGGTAGCGATACAGGTTCACTTCGCGGTGAAACACAGTCAGGAGTGTCGAGTCTATCGGTGCAACGCCTGCTCGACCGTTCCCGACTTGGACAATTCGCCGGGGAACGCGACCGGAGAGGGAAAGAGTTTCTTCAGAAGCGAATCCGAGATGGCCAGCCACGTGAGAACCGTTCACGCGCCTGCTACGCTCTCCGCCAGCAGCCCTCTCGCTACCAGTCCAGCTTCTACTCCTGGGATCACCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCACAGCCGCCTCTTCCTCGGGACCCAGATGCGTTTTCTGCGGAATTTTCTGCGGATCGGAGCTCGAGCTCCAACTTCACTTGGCCAGCCATTCCGCTAGCCTCTACAGATGTCCAGTCTGCAGAGAGGGTTTCGCCGTCGAGTTCTTGCTCGACAGGCACATTGCCCAGGCGCATCGTTCCGGCGATCATCGAGCCACCTCGAGAACCGCGTCCAGGGAAAACGGACGAATCGCCAGAAGCTCCAGATTGCAGGAAGAGAGTAAATCCCAGAAAAGGGGTCGTTCACCGGCATCGAGCAACAACAACCTTCCGAACCAACGCGATAACAACAACAAACGCGCCAACTACGTCGGCCCAGCCTCCCAGCAATGCGATCTCTGCGAGAGAGGAGAGTTCGCGAACGAAGCGGAACTTCAGGCTCACAAAAAGGTCGCTCACAGCCCTGCTGGCAAACTGCAGAACAAATCGTTGTCGAATCTCAGCATGAGCTGCGCCTATTGCGGAGAGGTGTGCCGGTCTCGAACCGAGCTCGAATCTCACACCAGAATTCAGCACGCGTCGAACGAGCCTGGAGGACGTCACAAGTGCAACATCTGCGACGAGGTCTGCCCCTCCGGAGCCAGTCTCGCCGAGCACAAACTGCAGAAACACTGCAAGATCCGGCTGAGCGACAGCTGCGTCGTCTGTCGCGGAAGCTTGACTTCGGAATCGCAGTTCCTCGAACACGTGCAAAGGCACAGCCTCGAGAACGTGGATCCTCAGCAACGGCACGACGCTTCTCTTCCGCATTTGCCCGCGGCCTGCGTCGTATGCAGACAAACGCTCATCACCGATCTCGAGTGTCGTCTTCACGCCAGACATCATCTCCGCGCTTCCGTCGAAACTCGCAGCCTCGGATCCAGTCCCAATCCCAGCCAGAAACCGATCCAGAATCCGAGCTGCTGTCTCTGTCTGAGGGATTACCACGTGGACGAGTTGGTCAGTCTGCCTCCGAGCCGCCTGACCGGAGGAGGACAGTCCCTCAGGGTCTGCAAGTCTTGCTACGTTCGTCACTCGCAAGGTCTGCCCATTCTGAACTCGCCTTACGAACCGACCAGGTTAAAATGGACGTCGAGCAAGGAACCGCCTCGAGGAGAAGGCTCGAGGGACAAATGGGAAACGGATCGTACAAACAACACCGAGGAGAAAACGGACCGAATAATACCGGACGACGGTATTAGATGCGACCAGTGCGGCCTCAAGTTCGAGGATTCCGAACAAGCGGAGAAACACAAAATCTTCGAGCACGAGAAAATTGGAGCTGCTTCGAACACCTACACCTGTATACAGTGTCAGATGTCTTTTTCGACCGAGGCCAAGATACAGCAACACGTGAGAAAGGATCACCTGGAATCGTCCGGGAAAGCTTCGGTGGATGCTCTCAGGTGCCATTTGTGTCTGTTCGAGGCCAGCAGTCCGTTACAATTACAGAGTCATTTGATAGAGCACACTTTTGCCGGATGCGCCGCTCTCAGCTGCTACATTTGTCAGTCTCTCTTCACTGCGCCCATCGGTCTTCAGAATCACATGCTGCAAGAACACGGTTTAGGTGCCCGCCCGTACGACTGTTCCAAGTGCGTCCTCAAGTTCTTCTTCAGAGCCGAGTTGGACCATCACGCGCTAACGTTCCATCGGCCCGGAGATGCAACCGAAACCGTGCAGAACGCCAACGAAACGAAACGAGACGCTGCTGCTGCCGAGCAGCAAAATTGCAAAGAGGAGATGATCACGGTAAAAGAAGAGCTACTCGCGGAAGCTGCGGAGGAAGACGAGGAAGAAATCAACGTGGAAGAGCAAGTGGAACAGGACGCCTCGGGAACGTTCAAACGATCGGACGCGGATCAAAAGTTTAAAACAGAGATAGAGAGTGATTCCGTTCACGAAAAGATTCATTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQDDQHKSKEVLGTGSSSWQSEDAGANSRRGGETPSSCATPTSVSFPSEPEVDADVAANADGNNANAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSHQGTNKLQPQEADHGRRSVSSHSTSSPPVASSPSPSLNLGPNPKSGLKSSQGSCSTTPILTSPLKLACMYCTRDSFSCMQQLQMHVHTMHRAILNDESVATVSPSGNGSSEQLVGYHRADKPSSERLEGSGSSVQEADHERERKRGTTEKDQYENGPFACNRCTIKFSALASLRDHLLSIHGIDQYGSAALMMCPLCSVPCTSAAAYAEHYVLRHCENRRPNHSLEARDYPETTELNGGYDSNTARNQKRREQTPTEPADLTNKHATETSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDLRQHPCPKCDATFQDKEDMLVHLTNHYLGQVSKEYACGACNNLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDTRVAIQVHFAVKHSQECRVYRCNACSTVPDLDNSPGNATGEGKSFFRSESEMASHVRTVHAPATLSASSPLATSPASTPGITAAAAAAAAAATAASSSGPRCVFCGIFCGSELELQLHLASHSASLYRCPVCREGFAVEFLLDRHIAQAHRSGDHRATSRTASRENGRIARSSRLQEESKSQKRGRSPASSNNNLPNQRDNNNKRANYVGPASQQCDLCERGEFANEAELQAHKKVAHSPAGKLQNKSLSNLSMSCAYCGEVCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGASLAEHKLQKHCKIRLSDSCVVCRGSLTSESQFLEHVQRHSLENVDPQQRHDASLPHLPAACVVCRQTLITDLECRLHARHHLRASVETRSLGSSPNPSQKPIQNPSCCLCLRDYHVDELVSLPPSRLTGGGQSLRVCKSCYVRHSQGLPILNSPYEPTRLKWTSSKEPPRGEGSRDKWETDRTNNTEEKTDRIIPDDGIRCDQCGLKFEDSEQAEKHKIFEHEKIGAASNTYTCIQCQMSFSTEAKIQQHVRKDHLESSGKASVDALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCVLKFFFRAELDHHALTFHRPGDATETVQNANETKRDAAAAEQQNCKEEMITVKEELLAEAAEEDEEEINVEEQVEQDASGTFKRSDADQKFKTEIESDSVHEKIHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962018; iTF_00964654; iTF_00962708; iTF_00964026;
90% Identity: iTF_00964026;
80% Identity: -