Basic Information

Insect: Megachile rotundata
Gene Symbol: -
Assembly: GCA_000220905.1
Location: NW:473161-476787[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.061 3.8 7.4 0.4 2 23 144 165 143 165 0.96

2 15 4.3e-05 0.0027 17.3 1.6 2 23 170 191 169 191 0.98

3 15 8.4e-06 0.00052 19.5 2.5 2 23 198 219 197 219 0.97

4 15 2.4e-06 0.00015 21.3 1.6 1 23 253 275 253 275 0.98

5 15 0.00023 0.014 15.0 0.2 1 23 281 303 281 303 0.98

6 15 1.5e-06 9e-05 21.9 1.8 1 23 309 331 309 331 0.97

7 15 5.9e-07 3.6e-05 23.2 1.7 1 23 337 359 337 359 0.96

8 15 2.3e-05 0.0014 18.2 0.6 1 23 365 387 365 387 0.98

9 15 2.1e-05 0.0013 18.3 6.8 1 23 393 415 393 415 0.97

10 15 5.9e-08 3.6e-06 26.3 1.0 1 23 420 442 420 442 0.97

11 15 0.0002 0.012 15.2 0.2 1 23 448 470 448 470 0.97

12 15 1.2e-06 7.4e-05 22.2 5.6 1 23 476 498 476 498 0.96

13 15 1.5e-06 9.4e-05 21.9 1.9 1 23 504 526 504 526 0.98

14 15 6.1e-06 0.00037 20.0 0.7 1 23 532 554 532 554 0.98

15 15 0.00024 0.015 15.0 2.3 1 23 560 583 560 583 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.061	3.8	7.4	0.4	2	23	144	165	143	165	0.96
2	15	4.3e-05	0.0027	17.3	1.6	2	23	170	191	169	191	0.98
3	15	8.4e-06	0.00052	19.5	2.5	2	23	198	219	197	219	0.97
4	15	2.4e-06	0.00015	21.3	1.6	1	23	253	275	253	275	0.98
5	15	0.00023	0.014	15.0	0.2	1	23	281	303	281	303	0.98
6	15	1.5e-06	9e-05	21.9	1.8	1	23	309	331	309	331	0.97
7	15	5.9e-07	3.6e-05	23.2	1.7	1	23	337	359	337	359	0.96
8	15	2.3e-05	0.0014	18.2	0.6	1	23	365	387	365	387	0.98
9	15	2.1e-05	0.0013	18.3	6.8	1	23	393	415	393	415	0.97
10	15	5.9e-08	3.6e-06	26.3	1.0	1	23	420	442	420	442	0.97
11	15	0.0002	0.012	15.2	0.2	1	23	448	470	448	470	0.97
12	15	1.2e-06	7.4e-05	22.2	5.6	1	23	476	498	476	498	0.96
13	15	1.5e-06	9.4e-05	21.9	1.9	1	23	504	526	504	526	0.98
14	15	6.1e-06	0.00037	20.0	0.7	1	23	532	554	532	554	0.98
15	15	0.00024	0.015	15.0	2.3	1	23	560	583	560	583	0.97

Sequence Information

Coding Sequence: ATGAAAACGAAGagTAAATTACAGCAAAtggaagattttaaaataaaagatgaacCAATGGATATGTTAAACATAGACAGTCAGGTTATGGACGAAAACATTGTAAGCGTTGTACTTAAAGAAGAACCCGGTGATAGATTTGATCCCGACTACATGGAGGACATCTGCTCTGGGACATTCGAGAAGGTATTTTTACCTATCGAAAATAACGAAGTTGACTTCTCCAATGAAATGGTAAAACTTGAATTGGATGGAGAATCTAGTAGTCATCAGAATTGGACAGCACAAATTGCTGGTACCAATTTGTGTGATAAAGAAGATGGTGCTATGCAAAGGTGCTTGGCAAgcacaaattttatacaagtaCAAGATGTTGAAAAACATTCTGGGTTTTGTACAAATGGACAGCAACccaagttttataaaatacaatgttCCATTTGTAAAAAATGGTTTTTGAACAATGATTCGATGGTTACTCATTTAAGGTTGCACTGCAGTGGAAACCAATGCGAAGTTTgccaacaaaattttcaagataattccagtttacatatacatatgttgaCTCATGTTGGGATGAGCCCACTAGAATGTAATATCTGTCAAAAGCGGTTTGCGTATAAATGGTGTTTACGCAGTCACATGCAAATGCACGTATTGGAAAAACCGTACGATAATGATCCGGTACATCAAGCGTTTATGAAAAGGCAAGATTCCGAGAACGACCAATCGATAAACGCGGGAGAAAGATTATTCGAATGCGATGTTTGTCATGCAACATTTAAGGAAAAATCTAGTCTGAATCGACATGTGCTTACCCATACGGAAGAAAGACCATACAAATGCGATATATGCGTTGCAGCATTTAGGGAAAaggcaaaattaaatatgcacATGACGTTGCACGAAGGAGAAAAGCAGTTCAAATGTACCATGTGTTACAGATCGTTTACACAGAAAACAGCACTAAATAATCACATGTTAGCGCACAGTGGTGAGAAACCACATGCATGCAACATTTGCGAGAAAACATATAGACGAAAGTCAGAGTTAATACGACACACGATGGTTCATACTGGCGAAAGACCATACGAATGCAAAGAATGTCTGATGACTTTTCGGGAAAAGGCGAaattaaattctcacatgcTTGTTCATACAGGTGAAAAACCACACGAGTGTCATATATGTCATAAAGCGTGCGCTCGCAAATCTGACCTTAACAGTCATATGCTATTGCATACCGGTGGTCAGTATGATTGTAAAGTTTgcgacaaaatatttactcgCAAATCTGATTTGAATCGGCATACTTTGATACATACAGGCGAAAAACCATTTGCTTGTGGCTTGTGTGACATGGCTTTCAGAGAGAAAACTAGATTAAATTCTCATATGCTTATACATACTGGTGACAAACGACACGCTTGTCACATTTGCCAGAAAACGTTTAAGGAAAAGTCTTCATTGCGAAAGCATATGTTAAGTCACACTGGTGACAGACCATACGAATGTTACGTGTGTCATAAAGCATTTACACAAAAAACAACGTTAAATAGCCACATATTAGTACACGCAGCAGAACGACCGTACGAATGCAGTGCgtgtcaaaaaatatttaaggacaaagcaacattaaaaaaacatttatcagTACATACAAACGAGAAAACTCACGAATGtctaatttgtttaaaaaagtttGCCCACAAAGCTGCATTAAATAGTCACTTATCAACAAATCATACGACCTAA
Protein Sequence: MKTKSKLQQMEDFKIKDEPMDMLNIDSQVMDENIVSVVLKEEPGDRFDPDYMEDICSGTFEKVFLPIENNEVDFSNEMVKLELDGESSSHQNWTAQIAGTNLCDKEDGAMQRCLASTNFIQVQDVEKHSGFCTNGQQPKFYKIQCSICKKWFLNNDSMVTHLRLHCSGNQCEVCQQNFQDNSSLHIHMLTHVGMSPLECNICQKRFAYKWCLRSHMQMHVLEKPYDNDPVHQAFMKRQDSENDQSINAGERLFECDVCHATFKEKSSLNRHVLTHTEERPYKCDICVAAFREKAKLNMHMTLHEGEKQFKCTMCYRSFTQKTALNNHMLAHSGEKPHACNICEKTYRRKSELIRHTMVHTGERPYECKECLMTFREKAKLNSHMLVHTGEKPHECHICHKACARKSDLNSHMLLHTGGQYDCKVCDKIFTRKSDLNRHTLIHTGEKPFACGLCDMAFREKTRLNSHMLIHTGDKRHACHICQKTFKEKSSLRKHMLSHTGDRPYECYVCHKAFTQKTTLNSHILVHAAERPYECSACQKIFKDKATLKKHLSVHTNEKTHECLICLKKFAHKAALNSHLSTNHTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539746;
90% Identity: iTF_00087361;
80% Identity: iTF_00962649;