Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756257.1:15138215-15140105[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.087 13 7.4 0.4 2 23 135 156 134 156 0.96

2 15 6.2e-05 0.0092 17.3 1.6 2 23 161 182 160 182 0.98

3 15 1.2e-05 0.0018 19.6 2.5 2 23 189 210 188 210 0.97

4 15 3.4e-06 0.0005 21.3 1.6 1 23 244 266 244 266 0.98

5 15 0.00032 0.048 15.0 0.2 1 23 272 294 272 294 0.98

6 15 2.1e-06 0.00031 21.9 1.8 1 23 300 322 300 322 0.97

7 15 8.4e-07 0.00013 23.2 1.7 1 23 328 350 328 350 0.96

8 15 3.2e-05 0.0049 18.2 0.6 1 23 356 378 356 378 0.98

9 15 3e-05 0.0045 18.3 6.8 1 23 384 406 384 406 0.97

10 15 8.4e-08 1.3e-05 26.3 1.0 1 23 411 433 411 433 0.97

11 15 0.00029 0.043 15.2 0.2 1 23 439 461 439 461 0.97

12 15 1.7e-06 0.00026 22.2 5.6 1 23 467 489 467 489 0.96

13 15 2.2e-06 0.00032 21.9 1.9 1 23 495 517 495 517 0.98

14 15 8.6e-06 0.0013 20.0 0.7 1 23 523 545 523 545 0.98

15 15 0.00034 0.05 15.0 2.3 1 23 551 574 551 574 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.087	13	7.4	0.4	2	23	135	156	134	156	0.96
2	15	6.2e-05	0.0092	17.3	1.6	2	23	161	182	160	182	0.98
3	15	1.2e-05	0.0018	19.6	2.5	2	23	189	210	188	210	0.97
4	15	3.4e-06	0.0005	21.3	1.6	1	23	244	266	244	266	0.98
5	15	0.00032	0.048	15.0	0.2	1	23	272	294	272	294	0.98
6	15	2.1e-06	0.00031	21.9	1.8	1	23	300	322	300	322	0.97
7	15	8.4e-07	0.00013	23.2	1.7	1	23	328	350	328	350	0.96
8	15	3.2e-05	0.0049	18.2	0.6	1	23	356	378	356	378	0.98
9	15	3e-05	0.0045	18.3	6.8	1	23	384	406	384	406	0.97
10	15	8.4e-08	1.3e-05	26.3	1.0	1	23	411	433	411	433	0.97
11	15	0.00029	0.043	15.2	0.2	1	23	439	461	439	461	0.97
12	15	1.7e-06	0.00026	22.2	5.6	1	23	467	489	467	489	0.96
13	15	2.2e-06	0.00032	21.9	1.9	1	23	495	517	495	517	0.98
14	15	8.6e-06	0.0013	20.0	0.7	1	23	523	545	523	545	0.98
15	15	0.00034	0.05	15.0	2.3	1	23	551	574	551	574	0.97

Sequence Information

Coding Sequence: ATGgaagattttaaaataaaagatgaACCAATGGATATGTTAAACATAGACAGTCAGGTTATGGACGAAAACATTGTAAGCGTTGTACTTAAAGAAGAACCTGGTGATAGATTTGATCCCGACTACATGGAGGACATCTGCTCTGGGACATTCGAGAAGGTATTTTTACCTATCGAAAATAATGAAGTTGACTTCTCCAATGAAATGGTAAAACTTGAATTGGATGGAGAATCTAGTAGTCATCAGAATTGGACAGCGCAAATTGCTGGTACCAATTTGTGTGATAAAGAAGATGGTGCTATGCAAAGGTGCTTGGCAAGCACAAATTTTATACAAGTACAAGATGTCGAAAAACATTCTGGGTTTTGTACAAATGGACAGCAACCcaagttttataaaatacaatgttCCATTTGTAAAAAATGGTTTTTGAACAATGATTCGATGGTTACTCATTTAAGGTTGCACTGCAGTGGAAACCAATGCGAAGTTTGCcaacaaaattttcaagataATTCCagtttacatatacatatgttgaCTCATGTTGGAATGAGCCCACTAGAATGTAATATCTGCCAAAAGCGGTTTGCGTATAAATGGTGTTTACGCAGTCACATGCAGATGCACGTATTGGAAAAACCGTACGATAATGATCCGGTACATCAAGCGTTTATGAAAAGGCAAGATTCTGAGAACGACCAATCGATAAACGCGGGAGAAAGATTATTCGAATGCGATGTTTGTCATGCAACGTTTAAGGAAAAATCTAGTCTGAATCGACACGTGCTTACCCATACGGAAGAAAGACCATACAAATGCGATATATGCGTTGCAGCATTTAGAGAAAAGGCAAAATTAAATATGCACATGACGTTGCACGAAGGAGAAAAGCAGTTCAAATGTACGATGTGTTACAGATCGTTTACACAGAAAACAGCACTAAATAATCACATGTTAGCGCACAGTGGTGAGAAACCACATGCATGCAATATTTGCGAGAAAACATATAGACGAAAATCAGAGTTAATAAGACACACGATGGTTCATACTGGCGAAAGACCATACGAATGCAAAGAATGTCTGATGACTTTTCGGGAAAAGGCGAAATTAAATTCTCACATGCTTGTTCATACAGGTGAAAAACCACACGAGTGTCATATATGTCATAAAGCGTGCGCTCGAAAATCTGACCTTAACAGTCATATGCTATTGCATACCGGTGGTCAGTATGATTGTAAAGTTTGCGACAAAATATTTACTCGCAAATCTGATTTGAATCGGCATACTTTGATACATACAGGCGAAAAACCATTTGCTTGTGGCTTGTGTGACATGGCTTTCAGAGAAAAAACTAGATTAAATTCTCATATGCTTATACATACTGGTGACAAACGACACGCTTGTCACATTTGCCAGAAAACGTTTAAGGAAAAATCTTCATTGCGAAAGCATATGTTAAGTCACACTGGTGATAGACCATACGAATGTTACGTGTGTCATAAAGCATTTACACAAAAAACAACGTTAAATAGCCACATATTAGTACACGCAGCAGAACGACCGTACGAGTGCAGTGCgtgtcaaaaaatatttaaggaTAAAGCAAcattaaaaaaacatttatcAGTACATACAAACGAGAAAACTCACGAATGtctaatttgtttaaaaaagttTGCCCACAAAGCTGCATTAAATAGTCACTTATCAACAAATCATACGACCTAA
Protein Sequence: MEDFKIKDEPMDMLNIDSQVMDENIVSVVLKEEPGDRFDPDYMEDICSGTFEKVFLPIENNEVDFSNEMVKLELDGESSSHQNWTAQIAGTNLCDKEDGAMQRCLASTNFIQVQDVEKHSGFCTNGQQPKFYKIQCSICKKWFLNNDSMVTHLRLHCSGNQCEVCQQNFQDNSSLHIHMLTHVGMSPLECNICQKRFAYKWCLRSHMQMHVLEKPYDNDPVHQAFMKRQDSENDQSINAGERLFECDVCHATFKEKSSLNRHVLTHTEERPYKCDICVAAFREKAKLNMHMTLHEGEKQFKCTMCYRSFTQKTALNNHMLAHSGEKPHACNICEKTYRRKSELIRHTMVHTGERPYECKECLMTFREKAKLNSHMLVHTGEKPHECHICHKACARKSDLNSHMLLHTGGQYDCKVCDKIFTRKSDLNRHTLIHTGEKPFACGLCDMAFREKTRLNSHMLIHTGDKRHACHICQKTFKEKSSLRKHMLSHTGDRPYECYVCHKAFTQKTTLNSHILVHAAERPYECSACQKIFKDKATLKKHLSVHTNEKTHECLICLKKFAHKAALNSHLSTNHTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539746;
90% Identity: iTF_00087361;
80% Identity: iTF_00963976;