Basic Information

Insect: Megachile rotundata
Gene Symbol: ZNF236
Assembly: GCA_000220905.1
Location: NW:969773-977678[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00087 0.054 13.2 2.7 2 23 173 194 172 194 0.96

2 26 7.4e-05 0.0046 16.5 1.1 1 23 200 222 200 222 0.98

3 26 1e-06 6.2e-05 22.4 0.7 2 23 228 249 228 249 0.97

4 26 0.0053 0.33 10.7 0.2 3 23 257 277 255 277 0.96

5 26 0.00034 0.021 14.5 0.5 2 23 288 309 288 309 0.98

6 26 5.3e-07 3.3e-05 23.3 1.1 1 23 330 352 330 352 0.99

7 26 8.4e-06 0.00052 19.5 0.9 1 20 358 377 358 380 0.96

8 26 3.9e-05 0.0024 17.4 0.6 1 23 386 409 386 409 0.94

9 26 0.0055 0.34 10.7 2.3 3 23 420 441 418 441 0.97

10 26 2.6e-06 0.00016 21.1 3.0 1 23 561 583 561 583 0.98

11 26 0.00023 0.014 15.0 3.3 1 23 589 611 589 611 0.99

12 26 0.062 3.8 7.4 1.9 1 23 617 639 617 639 0.96

13 26 0.0035 0.21 11.3 6.7 1 23 714 736 714 736 0.98

14 26 2.2e-05 0.0014 18.2 4.0 1 23 742 764 742 764 0.98

15 26 3.4e-05 0.0021 17.6 0.5 3 23 772 792 770 792 0.97

16 26 0.00029 0.018 14.7 7.6 1 23 798 820 798 820 0.98

17 26 0.0026 0.16 11.7 1.7 2 23 1168 1189 1167 1189 0.97

18 26 0.0008 0.049 13.3 3.1 1 23 1195 1217 1195 1217 0.98

19 26 0.0018 0.11 12.2 0.8 2 23 1224 1245 1223 1245 0.94

20 26 3.9e-07 2.4e-05 23.7 1.6 2 23 1316 1337 1315 1337 0.98

21 26 0.001 0.062 13.0 3.7 1 23 1343 1365 1343 1365 0.98

22 26 7.3e-06 0.00045 19.7 2.1 1 23 1371 1393 1371 1393 0.98

23 26 0.00049 0.03 14.0 2.5 1 23 1399 1421 1399 1421 0.98

24 26 3.5e-06 0.00022 20.7 0.6 2 23 1611 1632 1610 1632 0.97

25 26 9.5e-06 0.00059 19.4 4.5 1 23 1638 1660 1638 1660 0.98

26 26 5.6e-07 3.5e-05 23.2 0.7 1 23 1666 1689 1666 1689 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00087	0.054	13.2	2.7	2	23	173	194	172	194	0.96
2	26	7.4e-05	0.0046	16.5	1.1	1	23	200	222	200	222	0.98
3	26	1e-06	6.2e-05	22.4	0.7	2	23	228	249	228	249	0.97
4	26	0.0053	0.33	10.7	0.2	3	23	257	277	255	277	0.96
5	26	0.00034	0.021	14.5	0.5	2	23	288	309	288	309	0.98
6	26	5.3e-07	3.3e-05	23.3	1.1	1	23	330	352	330	352	0.99
7	26	8.4e-06	0.00052	19.5	0.9	1	20	358	377	358	380	0.96
8	26	3.9e-05	0.0024	17.4	0.6	1	23	386	409	386	409	0.94
9	26	0.0055	0.34	10.7	2.3	3	23	420	441	418	441	0.97
10	26	2.6e-06	0.00016	21.1	3.0	1	23	561	583	561	583	0.98
11	26	0.00023	0.014	15.0	3.3	1	23	589	611	589	611	0.99
12	26	0.062	3.8	7.4	1.9	1	23	617	639	617	639	0.96
13	26	0.0035	0.21	11.3	6.7	1	23	714	736	714	736	0.98
14	26	2.2e-05	0.0014	18.2	4.0	1	23	742	764	742	764	0.98
15	26	3.4e-05	0.0021	17.6	0.5	3	23	772	792	770	792	0.97
16	26	0.00029	0.018	14.7	7.6	1	23	798	820	798	820	0.98
17	26	0.0026	0.16	11.7	1.7	2	23	1168	1189	1167	1189	0.97
18	26	0.0008	0.049	13.3	3.1	1	23	1195	1217	1195	1217	0.98
19	26	0.0018	0.11	12.2	0.8	2	23	1224	1245	1223	1245	0.94
20	26	3.9e-07	2.4e-05	23.7	1.6	2	23	1316	1337	1315	1337	0.98
21	26	0.001	0.062	13.0	3.7	1	23	1343	1365	1343	1365	0.98
22	26	7.3e-06	0.00045	19.7	2.1	1	23	1371	1393	1371	1393	0.98
23	26	0.00049	0.03	14.0	2.5	1	23	1399	1421	1399	1421	0.98
24	26	3.5e-06	0.00022	20.7	0.6	2	23	1611	1632	1610	1632	0.97
25	26	9.5e-06	0.00059	19.4	4.5	1	23	1638	1660	1638	1660	0.98
26	26	5.6e-07	3.5e-05	23.2	0.7	1	23	1666	1689	1666	1689	0.97

Sequence Information

Coding Sequence: ATGTTGACGCGACACGATATAATTACGGAAAGTCCTCGCGTTGAGGCTATACCGATAAATCTTGTTACTACCGAGGATGGTAGAACGCTTTTGGCAGTGACAGaaCACAAGGACGGTATGATGGAAATCGTTGCGACTCCTGTTACGCTTATTGGTCAAAACGGATCACCTGCGTCGTTGATcgatgtaaaaaattttaatgaaaacctTATATTGCATTCTCCTATTTTTCAACTGAACATAGAAGATATCGTTGATGGATCAGAATTGCAACAGCCTGCAGAAGATATTGAACCTGATGCAATTACCACTGAACAGTTCAAATCTCAAGTATGCACAGAGGTAAAGAGAACACCCACGAACCAAGAGTACCAGTGTCCTCCGCAGAATGATTTGTTAATTAGTAAATGTGATGAGACTGCTGTACAAAAACCGGTGAGCACAGACTTAAAAAGGAACAGCCCTGGAAGACCCAAGAAGAACTCAGCTGGTTCTTTACAGGGGACAGGCAGTTTAAAATGTGACATTTGCCATCAAGAATTCGTTAAACGGACATTGTATCGAAAACACATGGAAAATCATGCAGAAGAGAAACCACACAGATGCCCAAAGTGCTCTGCATCCTTTAATGTTCCGACTAATTTCACTCTTCACATGGCGACTCACAATACGGGTGAACCAAAATGTCCAGAATGTGGGAAGAAGTTTACAAGGATGGCTAGTTTGAAGTCTCATATGTTGCTGCATGAGAAAGAGGAGAATTTGTTTTGTACCGAATGTGAAGATGCATTTTCAACTAAAGCTCAGTTGGATGCGCATCTGAAGCTTCACGGAGAAAAATGGGCAACAGAAGAAGTACGAAAGTGTAAGCTATGCAATAAACAGTTTGGTCAACCGGCTTTGTACAGGCTCCACATCCGTGAACATTACAGGTTGCAGACAAAAGTGGTAAAGCAGACAAAGAGAGGAACGAAACATAAAACGGTGTACAAATGTACAATATGTTTAAAGTCTTTCCAAAAACCCAGTCAGTTAATGCGCCATATCAGAGTACACACCGGCGAAAAACCGTTCAAGTGTACCGTGTGCAGTCGTGCATTCACTCAGAAAAGTTCTCTGCAAATTCATATGTGGCAGCACAACGGTATTCGACCACATGCTTGCGAGCTTTGCAATGCCAAATTCAGTCAAAAAGGTAATTTAAACGCCCACATAACAAGAGTTCATAACGTACCAGAGGGAGAGCCAATATATGGATGCAACTACTGTTCCTGCATCTTCAAAAAGCTAGGCAGTTTAAACGGCCACATGAAGCGCATGCATGCCGACATAGACGAGGAAGGAGTCGCCACTACTGATCGCTCCGACACCGTAGAGTCCGACATACGAGCAACCGTAGACAGCGTCATAACTCAGTTGGCATCTTTAGAAGCCACCACGGAGGAAGCTGAGAAATCAAACGACAAATCGAACTCATCTGTTGGAACGAAGAAAGATATTCTGCAAGAGGCTCTGAAGAATAGTGGTCTCCctagcaaaaataaaactgcGAACGAAGGTACGGAAACGAAGAAACTTGGGGCGCGCACTAATTTTGTGACGTTGCTGGACCGAGCGGCTGACGGTGGCACCAGaaaatatttgactatCAAACAACGGTGCGTGGGGAACATAAGATGGTATGCGTGCACCTTCTGCCACAAGGAGTTCAAGAAGTCGTCGGATCTGATACGACATCTACGTGTACATACACAAGAGAAACCTTTCAAGTGTACCCATTGTTATCGTTCGTTCGCTCTGAAATCCACCATGATAGCACACGAGCGCACTCATTCTGGCACGAAACGATACGCTTGCGACTCTTGCGACAAATCATTCGCGTGTCATGGAAGTTTGATTGGCCATACTAGATTACACGCAGAAGCTAAGAACGACTGTAATAAGATGGCTGACGACGACAAGAATCGTACGAAAGTTCAAACTAAAAAACCGAAGTTGTCGCCTGAGGCGGAGAGCTTGGTGGGTCAGGTGGTGTTGCAGGAACCTTTGGTGATCAGTGATGCTGGGAATAAAATTTGCGTGGCGCAGATAGCTTCGAAGGAGAAACGCTATGACGCGAGTACTGATCCGGCTAGACCGCATAAGTGTTGGGTTTGTCAGGCTGCTTTTAGGAAGATCAGTCACTTGAAGCAGCATCATCGTCGTCACACGGGTGAACGACCTTATGAGTGCACAAAGTGCGACAGgagGTTCACCTCAAACAGTGTGTTAAAGTCGCATCTACACACACATGAGGATTGGAGACCCTACGGTTGTCCCACATGTGATGCAAAGTTCTCTACTCAAAGCAGCATGAAGAGGCATCTGGTTACTCACAGTAACAAAAGACCGTTCATGTGTCCATATTGTCACAAGACTTTCAAAACTTATGTTAATTGTCGGAAACACATGAAGATACATAAACACGAATTAGCACAACGGCAGTTGGAGCAACAGAAAATGCAAGAACAGTCGAACCAGTCGGTATTGAAGGAAGGTTCCAAAGAAACGATCCTTGAGTCGAGTACTTTTCCTAATGCTACTAGTACAAACGACGTTAATGCACCTATTGTTACAACGTCCGCTCCAACGTTCACGGACAATCTCACCTTTTCTCGCCTTGGAACGGTTGAGATATCTTTTCAGTCGCAGCTCGGTTCTGATTTTTCGCAAACTTTCACCGAGCAGGATAAGACGAGACCACTTTTATCTGGAAACTGTGAACCTTCAACTTTTATTAATCATAATGTGTCGGAGACTGTGATGGCGAACCTTGAGAACTCACAGATGTTGCATGCTGATGAGACTGGGTCTGTTACTTTGCCAGTTTATCCTGGTGATCAAGCACTCACACCGGAGAGCATACGAGAAATAGAGGAGACGTTGAACCAACAGTTTTTCAACATAGGAATGAACATAACTCTAGGAAATAATTCTAGAAATTCTAACGACGTGAGCACGAATGATTTTGATAGTACAAAGCAGCAGCGACAAACCGTGTTGAATGTCATGTATGAGAATAATGGTAATGACACTAGTAACAACactaacaataataatgacgGTGGTAACAACGGTGTGGAACCATCAGCAGAACGTGTATTCTCTTCGCAGTTGGATTCGTTCGAGATTGATCATATCGCGTTGCAATCGGACACTGAAATCGATATTGGATTGGACACGAACGACTCAACGAGTATGACAAATATACTACCCAGAACTGTAAAAGAGGATCGTCTTTCCGAAGTCGATCAATCAGTGAAGTCCAGGGTGATGGTCATTTCTCAGGAAAAGAATCCAAGGAAAGAAGTAAACGAATTGGAAGCTGAAGAAGCCATTCAAAAGCAAAGCTCACTGCTCTTGGTAGAAGATTTCCGGGGAACAGAAGAGAAGAATCAGAAAGTACACACATCAGGTTTTGCGGAAATTGTCAACGGCAAAATGCAGAGGGAATCTTCGCTGCAATGTCACATGTGTAATCAACGAGGATTCACAGCGAGTGGATTGAAGGAACATTTGAAGACCCATCGCGAAACTAAGGAGTATCAGTGTACGGAATGCTCTTCAAAATTCTGTACGAACGGTGGCCTCAACAGGCATTCAAAGATACATGTTACTAAACAgtCATGGAAGTGTTCCTCCTGTGACAAATACTTTGACAACAGAACAGAGCTACAATCCCACAACGAAATTCACGAGATCTCTATTTGGAACGCCATATCAAGGCCACAAAATACGGAAAGCTCAGATTTACCGAACGATTCTTTAACTGACATCGCGATGGACACCGACTCCGCAGTTTCCGAAAGAGTCCTACTGGACACCGTAGCAGAAAAAGAAGCGATGGATCAAATAGAAGCAAGCTACACGAACCCAGAGAGAAGGGAACGAAAGGAATACACGAATAAGTGCAAATTCTGTCCAAAAACCTTTCGCAAACCTAGCGACCTCATAAGACACGTGCGTACACATACGGGTGAACGACCGTACAAGTGCGATTTCTGCAACAAAAGCTTCGCCGTGAAATGTACTCTGGACTCGCATACGAAAGTTCACACAGGGAAGAAGACGTTTAGGTGCCACGTTTGTAACAGCATGTTCGCGACCAAGGGTAGTCTGAAAGTGCACATGCGGTTGCATACAGGTTCGAAGCCGTTCAGATGTCCGGTTTGCGACTCGAGGTTTAGGACATCAGGTCACAGGAAGGTACACTTACTGAAGCACGTGCGCGAGCACAAGGAGCGACCAAAAAGGAAACAGAAGCACATGAAGGTTGCGGCCATAGCGGAAATAGCGGCAGATTTAGAGAAGCTAGGTAGAACCATAGGAAAGACTTTCGAATCCGATCAGCAGCTCTCTCGACCGTTGGAGACAATCAGCGTCGAAGCAACCGCCTGTTTGACCGACCAGATCAACTTCGAGACCGACGTGGACCCTAACATCGTGCAGAGTAACAATTCAGTGATGACCACGAGTGAAGGCAATCAGTTAGTTACCAATCTACACTTCCTGCTAACCAACGGACTCGTGACCATCCAAACCGACGAGTCGTTGTTGTCGCAATCGACGATCAACAACGCGTACAATCGTTCAACTGTGCCTACTGATTCTATGTGCGTGCCACTCTGCATCTCATCCGGCATCAACGAGGATCACACCAAGGAAGAGGCTCGCACGGGACAAGTGTTGAAGGCGCAGTTATCGTCGGTACAGGTGGAGCCACTACCCAAAGTCCCGCTCGATAAATCCCTGCCGACGGGGAGCAAGGCTAGCAAAGGCAACTCGAGGAAAGAGTGTGACGTCTGCGGGAAGACGTTCACGAAGCCGTACCAGGTTGAGAGGCATAAGAGAATTCACACGGGCGAGAGACCGTACAAGTGCGACCTCTGCACGAAATCGTTCGCTCAGAAATCTACTCTGCAAATGCATCAGAAACATCACACGGGAGACCGGCCGTACGCTTGTCCGTACTGCGAGTACTCCTTCACGCAGAAGGGCAATCTACGAACGCACGTGAAGCGGGTGCACCAGTTGGATACGATCAACGTCAAGAAGTTGAAACGTGGTCGCCAGTATTTTCTACCTAAGTCTCTTCAGGACAGCGTGGTCGAAACGAAGACCTTGAACTTGGACGACGTACCGTTCGTTGAATTCCTTAAATAG
Protein Sequence: MLTRHDIITESPRVEAIPINLVTTEDGRTLLAVTEHKDGMMEIVATPVTLIGQNGSPASLIDVKNFNENLILHSPIFQLNIEDIVDGSELQQPAEDIEPDAITTEQFKSQVCTEVKRTPTNQEYQCPPQNDLLISKCDETAVQKPVSTDLKRNSPGRPKKNSAGSLQGTGSLKCDICHQEFVKRTLYRKHMENHAEEKPHRCPKCSASFNVPTNFTLHMATHNTGEPKCPECGKKFTRMASLKSHMLLHEKEENLFCTECEDAFSTKAQLDAHLKLHGEKWATEEVRKCKLCNKQFGQPALYRLHIREHYRLQTKVVKQTKRGTKHKTVYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTVCSRAFTQKSSLQIHMWQHNGIRPHACELCNAKFSQKGNLNAHITRVHNVPEGEPIYGCNYCSCIFKKLGSLNGHMKRMHADIDEEGVATTDRSDTVESDIRATVDSVITQLASLEATTEEAEKSNDKSNSSVGTKKDILQEALKNSGLPSKNKTANEGTETKKLGARTNFVTLLDRAADGGTRKYLTIKQRCVGNIRWYACTFCHKEFKKSSDLIRHLRVHTQEKPFKCTHCYRSFALKSTMIAHERTHSGTKRYACDSCDKSFACHGSLIGHTRLHAEAKNDCNKMADDDKNRTKVQTKKPKLSPEAESLVGQVVLQEPLVISDAGNKICVAQIASKEKRYDASTDPARPHKCWVCQAAFRKISHLKQHHRRHTGERPYECTKCDRRFTSNSVLKSHLHTHEDWRPYGCPTCDAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAQRQLEQQKMQEQSNQSVLKEGSKETILESSTFPNATSTNDVNAPIVTTSAPTFTDNLTFSRLGTVEISFQSQLGSDFSQTFTEQDKTRPLLSGNCEPSTFINHNVSETVMANLENSQMLHADETGSVTLPVYPGDQALTPESIREIEETLNQQFFNIGMNITLGNNSRNSNDVSTNDFDSTKQQRQTVLNVMYENNGNDTSNNTNNNNDGGNNGVEPSAERVFSSQLDSFEIDHIALQSDTEIDIGLDTNDSTSMTNILPRTVKEDRLSEVDQSVKSRVMVISQEKNPRKEVNELEAEEAIQKQSSLLLVEDFRGTEEKNQKVHTSGFAEIVNGKMQRESSLQCHMCNQRGFTASGLKEHLKTHRETKEYQCTECSSKFCTNGGLNRHSKIHVTKQSWKCSSCDKYFDNRTELQSHNEIHEISIWNAISRPQNTESSDLPNDSLTDIAMDTDSAVSERVLLDTVAEKEAMDQIEASYTNPERRERKEYTNKCKFCPKTFRKPSDLIRHVRTHTGERPYKCDFCNKSFAVKCTLDSHTKVHTGKKTFRCHVCNSMFATKGSLKVHMRLHTGSKPFRCPVCDSRFRTSGHRKVHLLKHVREHKERPKRKQKHMKVAAIAEIAADLEKLGRTIGKTFESDQQLSRPLETISVEATACLTDQINFETDVDPNIVQSNNSVMTTSEGNQLVTNLHFLLTNGLVTIQTDESLLSQSTINNAYNRSTVPTDSMCVPLCISSGINEDHTKEEARTGQVLKAQLSSVQVEPLPKVPLDKSLPTGSKASKGNSRKECDVCGKTFTKPYQVERHKRIHTGERPYKCDLCTKSFAQKSTLQMHQKHHTGDRPYACPYCEYSFTQKGNLRTHVKRVHQLDTINVKKLKRGRQYFLPKSLQDSVVETKTLNLDDVPFVEFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963332; iTF_00961964; iTF_00964615; iTF_00962646;
90% Identity: iTF_00962646;
80% Identity: -