Basic Information

Insect: Megachile ligniseca
Gene Symbol: ZNF236
Assembly: GCA_945859565.1
Location: CAMAOB010000309.1:251430-258619[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0018 0.19 12.6 2.7 2 23 174 195 173 195 0.96

2 26 0.00011 0.011 16.5 1.1 1 23 201 223 201 223 0.98

3 26 1.4e-06 0.00015 22.4 0.7 2 23 229 250 229 250 0.97

4 26 0.0076 0.78 10.7 0.2 3 23 258 278 256 278 0.96

5 26 0.00048 0.05 14.4 0.5 2 23 289 310 289 310 0.98

6 26 7.5e-07 7.8e-05 23.2 1.1 1 23 331 353 331 353 0.99

7 26 1.2e-05 0.0012 19.5 0.9 1 20 359 378 359 381 0.96

8 26 5.5e-05 0.0057 17.4 0.6 1 23 387 410 387 410 0.94

9 26 0.0078 0.81 10.6 2.3 3 23 421 442 419 442 0.97

10 26 3.7e-06 0.00038 21.1 3.0 1 23 567 589 567 589 0.98

11 26 0.00032 0.033 15.0 3.3 1 23 595 617 595 617 0.99

12 26 0.088 9.1 7.3 1.9 1 23 623 645 623 645 0.96

13 26 0.005 0.51 11.2 6.7 1 23 725 747 725 747 0.98

14 26 3.2e-05 0.0033 18.1 4.0 1 23 753 775 753 775 0.98

15 26 4.8e-05 0.005 17.6 0.5 3 23 783 803 781 803 0.97

16 26 0.00041 0.042 14.6 7.6 1 23 809 831 809 831 0.98

17 26 0.029 3 8.8 1.2 2 23 1213 1234 1212 1234 0.96

18 26 0.0011 0.12 13.2 3.1 1 23 1240 1262 1240 1262 0.98

19 26 0.0092 0.94 10.4 0.7 2 23 1269 1290 1268 1290 0.94

20 26 5.5e-07 5.7e-05 23.7 1.6 2 23 1369 1390 1368 1390 0.98

21 26 0.0037 0.38 11.6 3.7 1 23 1396 1418 1396 1418 0.98

22 26 1e-05 0.0011 19.7 2.1 1 23 1424 1446 1424 1446 0.98

23 26 0.00069 0.071 13.9 2.5 1 23 1452 1474 1452 1474 0.98

24 26 5e-06 0.00052 20.7 0.6 2 23 1679 1700 1678 1700 0.97

25 26 1.4e-05 0.0014 19.3 4.5 1 23 1706 1728 1706 1728 0.98

26 26 8e-07 8.2e-05 23.2 0.7 1 23 1734 1757 1734 1757 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0018	0.19	12.6	2.7	2	23	174	195	173	195	0.96
2	26	0.00011	0.011	16.5	1.1	1	23	201	223	201	223	0.98
3	26	1.4e-06	0.00015	22.4	0.7	2	23	229	250	229	250	0.97
4	26	0.0076	0.78	10.7	0.2	3	23	258	278	256	278	0.96
5	26	0.00048	0.05	14.4	0.5	2	23	289	310	289	310	0.98
6	26	7.5e-07	7.8e-05	23.2	1.1	1	23	331	353	331	353	0.99
7	26	1.2e-05	0.0012	19.5	0.9	1	20	359	378	359	381	0.96
8	26	5.5e-05	0.0057	17.4	0.6	1	23	387	410	387	410	0.94
9	26	0.0078	0.81	10.6	2.3	3	23	421	442	419	442	0.97
10	26	3.7e-06	0.00038	21.1	3.0	1	23	567	589	567	589	0.98
11	26	0.00032	0.033	15.0	3.3	1	23	595	617	595	617	0.99
12	26	0.088	9.1	7.3	1.9	1	23	623	645	623	645	0.96
13	26	0.005	0.51	11.2	6.7	1	23	725	747	725	747	0.98
14	26	3.2e-05	0.0033	18.1	4.0	1	23	753	775	753	775	0.98
15	26	4.8e-05	0.005	17.6	0.5	3	23	783	803	781	803	0.97
16	26	0.00041	0.042	14.6	7.6	1	23	809	831	809	831	0.98
17	26	0.029	3	8.8	1.2	2	23	1213	1234	1212	1234	0.96
18	26	0.0011	0.12	13.2	3.1	1	23	1240	1262	1240	1262	0.98
19	26	0.0092	0.94	10.4	0.7	2	23	1269	1290	1268	1290	0.94
20	26	5.5e-07	5.7e-05	23.7	1.6	2	23	1369	1390	1368	1390	0.98
21	26	0.0037	0.38	11.6	3.7	1	23	1396	1418	1396	1418	0.98
22	26	1e-05	0.0011	19.7	2.1	1	23	1424	1446	1424	1446	0.98
23	26	0.00069	0.071	13.9	2.5	1	23	1452	1474	1452	1474	0.98
24	26	5e-06	0.00052	20.7	0.6	2	23	1679	1700	1678	1700	0.97
25	26	1.4e-05	0.0014	19.3	4.5	1	23	1706	1728	1706	1728	0.98
26	26	8e-07	8.2e-05	23.2	0.7	1	23	1734	1757	1734	1757	0.97

Sequence Information

Coding Sequence: ATGTTGACGCGACACGATATAATTACGGAAACTCCTCGCGTTGAGGCTATACCGATAAATCTTGTCACTACCGAGGATGGCAGAACGCTTTTGGCAGTGACAGAACACAAAGATGGTATGATGGAAATCGTTGCGACTCCTGTTACGCTTATTGGTCAAAACGGATCACCTGCGTCGTTGATCGATGTAAAAAATTTTAATGAAAATCTAATATTGCATTCTCCTATTTTTCAACTGAACATAGAAGATATCGTTGATGGATCAGAATTGCAACAGCCTATGGAAGATATTGAACCTGATGCAATTACTACTGAACGGTTCAAATCGCAAATATGCACAGAGTTAAAGTGCAGATCACCCACTACCCAGGAGTACCAGTGTCCTCCACAAAATGATTTGTTAGTTAGTAAATGTGATGAAACTGCTGTACAAAAATCAGTAAGCGCAGACTTAAAAAGGAACAGCCCTGGAAGACCTAAGAAGAACTCAGCTGGTTCTTTACAGGGGACAGGAAGTTTAAAATGCGACATTTGCCATCAAGAATTTGTTAAACGGACGTTGTATCGGAAACATATGGACAATCATGCAGAAGAGAAACCACATCGATGCCCAAAGTGCTCTGCATCCTTTAATGTTCCGACTAATTTCACTCTTCACATGGCGACTCATAATACGGGTGAACCAAAATGTCCAGAATGTGGAAAGAAGTTTACAAGGATGGCCAGTTTGAAGTCTCATATGTTGCTGCACGAAAAAGAGGAAAATTTGTTTTGTACTGAATGTGAAGATGCATTTTCAACTAAAGCTCAGTTGGATGCGCATTTGAAGCTTCACGGAGAAAAATGGGCGACAGAAGAAGCACGAAAGTGTAAACTATGCAATAAACAGTTTGGTCAACCGGCTTTGTACAGGCTTCATATTCGTGAACATTATAGGTTGCAGACGAAAGTGGTAAAGCAGACAAAAAGAGGGACGAAACATAAAACAGTATACAAATGTACGATATGTTTAAAGTCTTTCCAAAAACCCAGTCAGTTAATGCGCCATATCAGAGTACACACCGGCGAAAAACCGTTCAAGTGTACTGTGTGCAGTCGTGCGTTCACGCAAAAAAGTTCGCTCCAGATTCATATGTGGCAGCACAACGGTATTCGACCCCATGCTTGCGAGCTTTGCAATGCCAAATTCAGTCAAAAAGGTAATTTAAACGCTCACATAACAAGAGTTCATAATGTACCGGAGGGAGAGCCAATATATGGATGTAACTACTGTTCGTGCATATTCAAAAAGCTTGGCAGTTTAAACGGCCATATGAAACGCATGCATGCCGACATAGACGAGGAAGGAGTTGCTACTACTGATACTCGCTCTGCTGACACCGTAGAATCCGACATACGGGCAACTGTGGACAGCGTTATAACGCAGTTGGCATCTTTAGAAGCGACCACGGACGAAGCTGAGAAATCGAACGATAAATCGAACTTATTATCGGTGGGCACGATAAAGAAAGATATACTGCAAGAAGCGCTGAAGAATAGTGGTCTCCCTAGTAAAAATAAAACTGTGAACGAAGGTACAGCGGAAACGAAAAAACTTGGGGCGCGTACTAATTTCGTGACGTTACTGGATCGAGCGGCCGACGGTGGCACCAGAAAATATTTGACCATCAAACAACGATGCGTGGGGAACATAAGATGGTATGCGTGTACCTTTTGCCACAAGGAGTTCAAGAAGTCGTCGGATTTGATACGACATTTACGCGTACACACACAAGAGAAACCTTTCAAGTGTACCCATTGTTATCGTTCGTTCGCTCTGAAATCCACCATGATAGCACACGAACGCACTCATTCTGGCACGAAAAGATACGCTTGCGATTCTTGCGACAAATCATTCGCGTGTCATGGAAGTTTGATTGGCCATACTAGATTACATGCAAAATCTAAGAACGATTGCAATAAAACAATGGCTGACGACGACAAGAACACCGTCAATCGTACGAAAGTTCAAGCTAAGAGTAGACCGAAGTTATCGCCCGAAGCGGAGAGTTTGGTAGGCCAAGTGGTGTTACAAGAACCCTTGGTGATCAGTGATGCGGGGAATAAAATTTGCGTGGCACAAATAGCTTCGAAAGAAAAACGTTACGACGCGAGTACCGATCCAGCTAGACCGCATAAATGTTGGGTTTGCCAGGCAGCGTTCAGAAAGATCAGTCACTTGAAGCAACATCATCGTCGACACACGGGTGAACGTCCTTATGAATGCACAAAGTGCGACAGGAGGTTCACGTCAAACAGTGTGTTAAAGTCACATCTACACACGCACGAGGATTGGAGACCGTACGGTTGTCCCACATGCGACGCGAAGTTCTCTACGCAAAGTAGCATGAAAAGGCATTTGGTTACTCACAGTAACAAAAGACCGTTCATGTGTCCGTATTGCCACAAGACTTTTAAAACATACGTTAATTGCCGGAAACATATGAAGATACATAAACACGAATTAGCACAACGGCAGTTGGAGCAACAGAAAATCCAAATGCAAGAACAATCATCGGACCAGTCGATTTTGAAAGAAGGTTCTAAAGAAACGACCATTCTCGAATCGAGTTCAACTTTTGTTCCTAACGCTACTAGTACAAACATTGTCGCTAATGCCCCTGCTATCGTTACAACGTCCGCTCCCACGTTTACAGACAATCTTACCTTTTCTCGCCTTGGCACGGTTGAGATATCGTTTCAGTCGCAGCTCGGTTCTGATTTTTCACAAACTTTTACCGAACAGGACAAAACGAGACCACTTCTATCCGGAAACTGTGAACCTTCAACTTTTATTAATCATAATGTGTCGGAGACAGTAATGGCGAACCTTGAAAACTCACAGATGTTACATGCCGACGAAACTGGTTCTGTTACTTTGCCAGTTTATCCTGGTGATCAAGCACTCACACCGGAGAGCATACGAGAAATAGAGGAGACGTTGAATCAACAGTTTTTTAACATTGGAATGAATATTACTCTAGGAAATAATTCTAGACATTCGAACGACGTGAGCACGAATGATTTTGATAACACGAAGGTACAACACCGACAAACCGTGTTGAATGTTATGTATGAGAACAGTGCTAATGACACTAGTAACAACACTAGTAACAACAACAACAACAATGACGGTGGTAACAACGTTGTTGTCGACGGTGTAGAACCATCCGAAGAACGTGTATTCTCTTCGCAGTTGGATTCGTTCGAGATTGATCATATCGCGTTACAATCGGACACTGAAATCGATATTGGATTGGATACGAACGATTCAACGAGTATGACGAATATACTACCCAGGACCGTAAAAGAAGATCGCCTTCCTGTTTCCGAAGTCGGCCGGGATCAATCAGGAAAGTCCAGTTTGCAAAGGGTGATGGTTATTTCGCAAGAAAAGAATCTGCCAAGAAAAGAAGTAACGAACGAATTGGAAGCAACTGAAGAAGCCATTCGAAAGCAGCAAAGTCCATTGCTCTTGGTAGAAGATTTCCGGGGAACAGTAGAAGAGGAGATAAAGAATCAAACGAAAGTACAGCACACGACGTCATCCGGTTTTGCAGAAATTGTCAATGACAAAATGCAGCGAGAATCTTCTTTGCAATGTCATATGTGCAATCAACGAGGATTTACGGCGATCGGATTAAAGGAACATTTGAAGACACATCGTGAAACTAAGGAATATCAGTGTACGGAATGCTCTTCAAAATTTTGCACAAACGGTGGCCTCAACAGACATTCGAAGATACATGTTACTAAACAATCATGGAAGTGTTCCTCCTGCGAGAAATACTTTGACAACAGAACAGAGTTACAATCCCATAACGAAATTCATGAAATCTCTATTTGGAACGCTATATCTACGAGGCCCCCAAACACGGAAAACTCAGATTTACAGCCAGTCGCGGATAACGGTTCGTCATTGAATGACATCGCGATAGATACCGACTCTGCAGTCTCCGAAAGAGTCTTATTGGACACCGTAGCGGAAAAAGAAGCGATGGATCAAATAGAAGCAAGTTACACGAATGTCTCAGGAGAGAGAAGGGAACGGAAGGAGTATAcgaacaagtgtaaattttgtccgaaaacttttcgcaaaccaagcgatcttataaggcacgtgcgtacacatacgggcgaacgaccgtataagtgcgatttctgcagcaaaagtttcgccgtgaaatgtactctggattcgcacacaaaagttcacacaggcaagaaaacgtttcggtgccatgtttgtaacagcatgttcgcgaccaagggtagtctaaaagtccacatgcggttacaTACAGGTTCGAAGCCGTTCAGGTGTCCCGTTTGCGACTCGAGATTTAGGACGTCGGGTCACAGGAAGGTACATTTACTGAAACACGTGCGTGAGCACAAAGAGCGTCCAAAAAGGAAACAGAAGCACATGAAAGTTGCGGCCATAGCGGAAATAGCGGCTGATTTAGAAAAGCTAGGTAGAACCATAGGAAAGACGAGTTTCGAATCGGATCAGCAACAGCAACTCTCTCGGGTAAAAGATTATCCTCAGTTGGAAACAATTAGCGTCGAGGCGACCGCTGCCTGTTTGACCGATCAGATCAACTTTGAGACCGACGTTGATCCTGGTATCGTATCGAGTAATAATTCAGTGATGACCACGAACGAAGGTAATCAGTTAGTTACTAATTTACATTTTCTGCTAACCAACGGACTCGTGACTATCCAAACCGACGAGTCGTTGTTGTCGCAATCGGCAACGATTAACAATGCATCGTACAATCGTTCAACTGTGGCTGCTGACTCGATGTGCGTGCCAACACTCTGCATTTCATCCGGTATTAACGATGATCACACCAAGGATGGGGTTCGTACGGGACAAGTATTGAAGGCACAGTTATCGTCGATACAGGTGGAACAACCGTTACCAAAAGTTCCGCTCGATAAATCCCTGCCGACAGGAAGTAAAACAGCTAACAAAGGCAACTCGTCGAGGAAAgagtgtgatgtttgcgggaagacgtttacgaagccgtatcaggttgaaaggcataaaagaattcatacgggcgagagaccgtacaaatgcgatctctgcacgaaatcgttcgcccaaaaatctactctgcaaatgcatcagaaacatcatacaggagatcggccgtacgcatgcccgtactgcgagtactctttcacgcagaaaggcaatctccgaacacacgtGAAACGGGTGCACCAATTGGATACGATCAACGTTAAGAAGTTGAAGCGTGGTCGCCAGTATTTTCTACCTAAATCTCTTCAAGACAGCGTGGTCGAAACGAAGAGTTTGAATTTGGACGACGTACCGTTCGTTGAATTCCTTAAATAG
Protein Sequence: MLTRHDIITETPRVEAIPINLVTTEDGRTLLAVTEHKDGMMEIVATPVTLIGQNGSPASLIDVKNFNENLILHSPIFQLNIEDIVDGSELQQPMEDIEPDAITTERFKSQICTELKCRSPTTQEYQCPPQNDLLVSKCDETAVQKSVSADLKRNSPGRPKKNSAGSLQGTGSLKCDICHQEFVKRTLYRKHMDNHAEEKPHRCPKCSASFNVPTNFTLHMATHNTGEPKCPECGKKFTRMASLKSHMLLHEKEENLFCTECEDAFSTKAQLDAHLKLHGEKWATEEARKCKLCNKQFGQPALYRLHIREHYRLQTKVVKQTKRGTKHKTVYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTVCSRAFTQKSSLQIHMWQHNGIRPHACELCNAKFSQKGNLNAHITRVHNVPEGEPIYGCNYCSCIFKKLGSLNGHMKRMHADIDEEGVATTDTRSADTVESDIRATVDSVITQLASLEATTDEAEKSNDKSNLLSVGTIKKDILQEALKNSGLPSKNKTVNEGTAETKKLGARTNFVTLLDRAADGGTRKYLTIKQRCVGNIRWYACTFCHKEFKKSSDLIRHLRVHTQEKPFKCTHCYRSFALKSTMIAHERTHSGTKRYACDSCDKSFACHGSLIGHTRLHAKSKNDCNKTMADDDKNTVNRTKVQAKSRPKLSPEAESLVGQVVLQEPLVISDAGNKICVAQIASKEKRYDASTDPARPHKCWVCQAAFRKISHLKQHHRRHTGERPYECTKCDRRFTSNSVLKSHLHTHEDWRPYGCPTCDAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAQRQLEQQKIQMQEQSSDQSILKEGSKETTILESSSTFVPNATSTNIVANAPAIVTTSAPTFTDNLTFSRLGTVEISFQSQLGSDFSQTFTEQDKTRPLLSGNCEPSTFINHNVSETVMANLENSQMLHADETGSVTLPVYPGDQALTPESIREIEETLNQQFFNIGMNITLGNNSRHSNDVSTNDFDNTKVQHRQTVLNVMYENSANDTSNNTSNNNNNNDGGNNVVVDGVEPSEERVFSSQLDSFEIDHIALQSDTEIDIGLDTNDSTSMTNILPRTVKEDRLPVSEVGRDQSGKSSLQRVMVISQEKNLPRKEVTNELEATEEAIRKQQSPLLLVEDFRGTVEEEIKNQTKVQHTTSSGFAEIVNDKMQRESSLQCHMCNQRGFTAIGLKEHLKTHRETKEYQCTECSSKFCTNGGLNRHSKIHVTKQSWKCSSCEKYFDNRTELQSHNEIHEISIWNAISTRPPNTENSDLQPVADNGSSLNDIAIDTDSAVSERVLLDTVAEKEAMDQIEASYTNVSGERRERKEYTNKCKFCPKTFRKPSDLIRHVRTHTGERPYKCDFCSKSFAVKCTLDSHTKVHTGKKTFRCHVCNSMFATKGSLKVHMRLHTGSKPFRCPVCDSRFRTSGHRKVHLLKHVREHKERPKRKQKHMKVAAIAEIAADLEKLGRTIGKTSFESDQQQQLSRVKDYPQLETISVEATAACLTDQINFETDVDPGIVSSNNSVMTTNEGNQLVTNLHFLLTNGLVTIQTDESLLSQSATINNASYNRSTVAADSMCVPTLCISSGINDDHTKDGVRTGQVLKAQLSSIQVEQPLPKVPLDKSLPTGSKTANKGNSSRKECDVCGKTFTKPYQVERHKRIHTGERPYKCDLCTKSFAQKSTLQMHQKHHTGDRPYACPYCEYSFTQKGNLRTHVKRVHQLDTINVKKLKRGRQYFLPKSLQDSVVETKSLNLDDVPFVEFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963973;
90% Identity: iTF_00962646;
80% Identity: -