Basic Information

Insect: Megachile leachella
Gene Symbol: ZNF236
Assembly: GCA_963576845.1
Location: OY756252.1:3953852-3961101[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0013 0.19 13.2 2.7 2 23 173 194 172 194 0.96

2 26 0.00011 0.016 16.6 1.1 1 23 200 222 200 222 0.98

3 26 1.5e-06 0.00022 22.4 0.7 2 23 228 249 228 249 0.97

4 26 0.0077 1.2 10.7 0.2 3 23 257 277 255 277 0.96

5 26 0.00049 0.074 14.5 0.5 2 23 288 309 288 309 0.98

6 26 7.7e-07 0.00011 23.3 1.1 1 23 330 352 330 352 0.99

7 26 1.2e-05 0.0018 19.5 0.9 1 20 358 377 358 380 0.96

8 26 5.6e-05 0.0084 17.4 0.6 1 23 386 409 386 409 0.94

9 26 0.008 1.2 10.7 2.3 3 23 420 441 418 441 0.97

10 26 3.8e-06 0.00056 21.1 3.0 1 23 561 583 561 583 0.98

11 26 0.00033 0.049 15.0 3.3 1 23 589 611 589 611 0.99

12 26 0.089 13 7.4 1.9 1 23 617 639 617 639 0.96

13 26 0.005 0.75 11.3 6.7 1 23 711 733 711 733 0.98

14 26 3.2e-05 0.0048 18.2 4.0 1 23 739 761 739 761 0.98

15 26 4.9e-05 0.0074 17.6 0.5 3 23 769 789 767 789 0.97

16 26 0.00042 0.062 14.7 7.6 1 23 795 817 795 817 0.98

17 26 0.0037 0.56 11.7 1.7 2 23 1169 1190 1168 1190 0.97

18 26 0.0012 0.17 13.3 3.1 1 23 1196 1218 1196 1218 0.98

19 26 0.0027 0.4 12.2 0.8 2 23 1225 1246 1224 1246 0.94

20 26 5.6e-07 8.4e-05 23.7 1.6 2 23 1317 1338 1316 1338 0.98

21 26 0.0038 0.57 11.7 3.7 1 23 1344 1366 1344 1366 0.98

22 26 1.1e-05 0.0016 19.7 2.1 1 23 1372 1394 1372 1394 0.98

23 26 0.0007 0.11 14.0 2.5 1 23 1400 1422 1400 1422 0.98

24 26 5.1e-06 0.00076 20.7 0.6 2 23 1609 1630 1608 1630 0.97

25 26 1.4e-05 0.0021 19.4 4.5 1 23 1636 1658 1636 1658 0.98

26 26 5.5e-07 8.2e-05 23.8 1.1 1 23 1664 1687 1664 1687 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0013	0.19	13.2	2.7	2	23	173	194	172	194	0.96
2	26	0.00011	0.016	16.6	1.1	1	23	200	222	200	222	0.98
3	26	1.5e-06	0.00022	22.4	0.7	2	23	228	249	228	249	0.97
4	26	0.0077	1.2	10.7	0.2	3	23	257	277	255	277	0.96
5	26	0.00049	0.074	14.5	0.5	2	23	288	309	288	309	0.98
6	26	7.7e-07	0.00011	23.3	1.1	1	23	330	352	330	352	0.99
7	26	1.2e-05	0.0018	19.5	0.9	1	20	358	377	358	380	0.96
8	26	5.6e-05	0.0084	17.4	0.6	1	23	386	409	386	409	0.94
9	26	0.008	1.2	10.7	2.3	3	23	420	441	418	441	0.97
10	26	3.8e-06	0.00056	21.1	3.0	1	23	561	583	561	583	0.98
11	26	0.00033	0.049	15.0	3.3	1	23	589	611	589	611	0.99
12	26	0.089	13	7.4	1.9	1	23	617	639	617	639	0.96
13	26	0.005	0.75	11.3	6.7	1	23	711	733	711	733	0.98
14	26	3.2e-05	0.0048	18.2	4.0	1	23	739	761	739	761	0.98
15	26	4.9e-05	0.0074	17.6	0.5	3	23	769	789	767	789	0.97
16	26	0.00042	0.062	14.7	7.6	1	23	795	817	795	817	0.98
17	26	0.0037	0.56	11.7	1.7	2	23	1169	1190	1168	1190	0.97
18	26	0.0012	0.17	13.3	3.1	1	23	1196	1218	1196	1218	0.98
19	26	0.0027	0.4	12.2	0.8	2	23	1225	1246	1224	1246	0.94
20	26	5.6e-07	8.4e-05	23.7	1.6	2	23	1317	1338	1316	1338	0.98
21	26	0.0038	0.57	11.7	3.7	1	23	1344	1366	1344	1366	0.98
22	26	1.1e-05	0.0016	19.7	2.1	1	23	1372	1394	1372	1394	0.98
23	26	0.0007	0.11	14.0	2.5	1	23	1400	1422	1400	1422	0.98
24	26	5.1e-06	0.00076	20.7	0.6	2	23	1609	1630	1608	1630	0.97
25	26	1.4e-05	0.0021	19.4	4.5	1	23	1636	1658	1636	1658	0.98
26	26	5.5e-07	8.2e-05	23.8	1.1	1	23	1664	1687	1664	1687	0.97

Sequence Information

Coding Sequence: ATGTTGACGCGACACGATATAATTACGGAAAGCCCTCGCGTTGAGGCTATACCGATAAATCTTGTTACTACCGAGGATGGTAGAACGCTTTTGGCAGTGACAGAACACAAGGACGGTATGATGGAAATCGTTGCGACTCCTGTTACGCTTATAGGTCAAAACGGATCACCTGCGTCGTTGATCgatgtaaaaaattttaatgaaaacctTATATTGCATTCTCCTATTTTTCAACTGAACATAGAAGATATCGTTGATGGATCAGAATTACAACAGCCTACAGAAGATATTGAACCTGATGTAATTGCAACTGAACAGTTCAAATCACAAGTATGCACAGAGGTGAAGAGAACACCGACGAATCAAGAGTACCAGTGTCCTCCCCAAAATGATTTGTTAGTTAGTAAATGTGATGAAACTGCTGTACAAAAACCGGTGAGCACAGACTTAAAAAGGAACAGCCCTGGAAGACCTAAGAAGAACTCAGCTGGTTCTTTACAGGGGACAGGCAGTTTAAAATGTGACATTTGCCATCAAGAATTTGTTAAACGGACATTGTATAGAAAACACATGGAAAATCATGCAGAAGAGAAACCACACAGATGCCCAAAGTGCTCTGCATCCTTTAATGTTCCGACTAATTTCACTCTTCACATGGCGACTCACAATACGGGTGAACCAAAATGTCCAGAATGTGGGAAGAAGTTTACGAGGATGGCTAGTTTGAAGTCTCACATGTTGCTGCATGAGAAAGAGGAGAATTTGTTTTGTACCGAATGTGAAGACGCATTTTCAACTAAAGCTCAGTTGGATGCGCACTTAAAGCTTCATGGAGAAAAATGGGCGACAGAAGAAGCACGAAAGTGTAAGCTATGCAATAAACAGTTTGGTCAACCAGCCTTGTACAGGCTTCACATCCGTGAACATTATAGGTTGCAGACAAAAGTGGTAAAGCAGACAAAGAGAGGAACGAAACATAAAACGGTGTACAAATGTACAATATGTTTAAAGTCTTTCCAAAAACCCAGTCAGTTAATGCGCCATATCAGAGTACACACCGGAGAAAAACCTTTCAAGTGTACCGTGTGCAGTCGTGCATTCACTCAAAAGAGTTCTCTGCAAATTCACATGTGGCAGCACAATGGTATTCGACCACATGCTTGCGAGCTTTGCAATGCCAAATTCAGTCAAAAAGGTAATTTAAATGCTCATATAACAAGAGTACATAACGTACCAGAGGGAGAGCCAATATATGGCTGCAACTACTGTTCCTGTATCTTCAAAAAGCTAGGCAGTTTAAACGGCCACATGAAGCGTATGCACGCCGACATCGACGAGGAAGGAGTCGCCACCGCTGATCGTTCTGACACCGTAGAATCCGACATACGTGCAACCGTAGACAGCGTCATAACTCAGCTAGCATCTTTAGAAGCCACCACAGAGGAGGCTGAGAAATCGAACGACAAATCAAACTCATCTGTGAGCGCGAAGAAAGATATTTTACAAGAGGCTCTGAAGAACAGTGGTCTCCCTAGCAAAAATAAAACTGCGAACGAAGGTACGGAAAATAAGAAACTTGGGGCGCGCACTAATTTTGTGACGTTGCTGGACCGAGCGGCTGACGGTGGCACCAGGAAATATTTGACCATCAAACAACGGTGCGTGGGGAACATAAGATGGTATGCGTGCACCTTCTGCCACAAAGAGTTCAAGAAGTCGTCGGATCTGATACGACACTTACGTGTACATACACAGGAGAAACCTTTCAAGTGTACCCATTGTTATCGTTCGTTCGCTCTGAAATCCACCATGATAGCACACGAGCGCACTCATTCTGGCACGAAACGCTACGCTTGTGATTCTTGCGACAAATCATTCGCGTGTCATGGGAGTTTGATTGGCCATACTAGATTACACGCGAAAGCTAAGAACGACTGTAAAATGACTGACGACGACAAGAAGAAAGTTCAGGCTAAAAAACCGAAGTTGTCCCCTGAAGCAGAGAGCTTGGTGGGTCAGGTGGTGTTGCAGGAACCTTTGGTGATCAGTGATGCTGGGAATAAAATTTGCGTGGCGCAGATAGCTTCGAAGGAGAAACGTTATGACGCGAGTACTGATCCGGCTAGACCACATAAGTGTTGGGTTTGTCAAGCGGCGTTTAGGAAGATTAGTCATTTGAAGCAGCACCATCGTCGACACACGGGTGAACGACCTTATGAATGTACAAAGTGTGATAGgagGTTCACATCAAACAGTGTGTTAAAGTCACACCTACACACACATGAAGATTGGAGACCATACGGTTGTCCCACATGTGATGCAAAGTTTTCCACACAAAGCAGCATGAAGAGGCATTTAGTTACTCACAGTAACAAGAGACCCTTCATGTGTCCATATTGCCACAAGACGTTCAAAACTTATGTGAACTGTAGGAAACACATGAAGATACACAAACACGAATTAGCACAACGGCAGTTGGAGCAACAGAAAATGCAAGAACAGTCGAACCAGTCGGTTCTGAAAGAAGGTTCTAAAGAAATTCTTGAGTCGAGTTCTTTTCCTACTAGTGCAAACGTCGCTACAAGTACAAACGTTGTTAATACACCTATCGTTACAACGACTGCTCCAACGTTCACGGATAATCTTACCTTTTCTCGCCTTGGAACGGTTGAGATATCGTTTCAGTCGCAGCTTGGTTCTGATTTTTCACAGACTTTTAGTGAGCAGGACAAGGCGAGATCACTTTTAACTGGAAGCTGTGAACCTTCAACTTTTATTAATCATAATGTGTCGGAGACTGTGATGGCGAACCTTGAGAACTCACAGATGTTGCATGCTGATGAGACTGGGTCTGTTACTTTGCCGGTTTATCCTGGTGATCAAGCACTCACACCGGAGAGCATACGAGAAATAGAAGAGACGTTGAATCAACAGTTTTTCAACATTGGAATGAACATTACTCTAggaaataattctagaaattcgaaCGACGTGAGCACGAATGATTTTGATAGTACAAAAGTGCAGCAACGACAAACTGTGTTAAATGTCATGTATGAGAACAGTGGTAATGACGCTAGTAACAACACTAACAACAACAACGACAGTGGTAACAACGGTGTAGAACCATCAGCAGAACGTGTATTCTCTTCGCAGTTGGATTCCTTCGAGATTGATCATATCGCATTGCAATCGGACACTGAAATCGATATTGGATTGGACACGAACGACTCAACTAGTATGACAAATATACTACCCAGAACTGTAAAAGAGGATCGTCTTACCGAAGTCGATCAATCAGTGAAGTCCAGGGTGATGGTCATTTCTCAGGAAAAGAACCCAAGGAAAGAAGTAAACGAATTGGAAGCTGAAGAAGCCATTCAAAAGCAAAGCCCACTGCTCTTGGTAGAAGATTTCCGGGGAACTGAAGAGAAGAATCAGAAAGTACAACACACAGGTTTTGCAGAAATTGTGAACGGCAAAATGCAGAGGGACTCTTCACTGCAATGTCATATGTGCAATCAACGAGGATTCACAGCAAGTGGATTGAAGGAACATTTGAAGACCCATCGTGAAACTAAGGAGTATCAGTGTACGGAGTGCTCTTCAAAATTCTGCACAAATGGTGGCCTCAACAGGCATTCAAAGATACATGTTACTAAACAatcATGGAAGTGTTCTTCCTGTGACAAATACTTTGACAACAGAACAGAATTACAGTCCCACAACGAAATTCATGAAATCTCCATTTGGAACGCTATATCAAGGCCCCCAAATACTGAAAGCTCAGATTTACAGAATGGTTCCTTAACTGACATCGCAATAGACACCGATTCCGCAGTATCCGAAAGAGTTCTACTGGACACTGTAGCAGAAAAAGAAGCGATGGATCAAATAGAAGCAAGCTACACGAACCCAGAGAGAAGGGAGCAAAAGGAGTACACGAACAAGTGCAAGTTCTGTCCAAAAACCTTCCGCAAACCTAGCGACCTCATAAGGCACGTGCGTACACATACTGGCGAACGACCGTACAAATGCGATTTCTGTAGCAAAAGCTTCGCCGTGAAATGTACTCTGGACTCGCATACAAAAGTGCACACAGGGAAGAAGACATTCAGGTGCCACGTTTGTAACAGCATGTTCGCAACCAAGGGTAGTTTAAAAGTGCACATGCGGTTGCATACAGGTTCGAAGCCGTTCAGATGTCCCGTCTGCGACTCAAGGTTTAGAACATCAGGTCATAGGAAGGTACACTTACTGAAACACGTGCGTGAACACAAAGAGCGTCCAAAAAGAAAGCAGAAGCACATGAAAGTCGCAGCCATAGCAGAAATAGCGGCTGATTTAGAGAAGCTGGGTAGAACCATAGGAAAGACCTTCGAATCGGATCAGCAGCTCTCTCGACCATTGGAGACAATCAGCGTCGAGGCGACCGCCTGTTTGACCGACCAGATCAACTTCGAGACCGACGTGGATCCTAACATCGTGCAGAGTAACAATTCAGTGATGAACGAAGGAAATCAGCTAGTTACCAATCTACACTTCCTGTTAACTAATGGACTCGTGACCATCCAAACCGACGAGTCGCTGCTGTCGCAATCGAATATTAACAACGCGTACAATCGCTCAACTGTGGCTACCGATTCCATGTGTGTGCCTCTATGCATCTCATCGGGTATTAATGAAGATCACACCAAGGAAGAGGTTCGTCCAGGACAAGTGTTGAAGGCGCAGCTATCGTCGGTACAGGTAGAACTACCTAAAGTCCCGCTTGATAAATCCCTGCCCACGGGGAGTAAAGCTAGCAAGGGCAACTCGAGGAAAGAATGTGACGTCTGCGGGAAGACGTTCACGAAGCCGTACCAGGTTGAGAGGCATAAAAGAATTCACACGGGCGAGAGACCCTACAAGTGCGACCTCTGCACGAAATCGTTCGCTCAGAAATCCACTCTGCAGATGCATCAGAAACATCACACGGGAGACCGGCCGTACTCCTGTCCGTACTGCGAGTACTCCTTCACGCAGAAGGGTAATCTACGGACGCACGTGAAACGGGTGCACCAGTTGGATACGATCAACGTCAAGAAGTTGAAACGTGGTCGCCAGTATTTTCTACCTAAGTCTCTTCAGGACAGCGTGGTCGAAACGAAGACCTTGAACTTGGACGACGTACCGTTCGTTGAATTCCTTAAATAG
Protein Sequence: MLTRHDIITESPRVEAIPINLVTTEDGRTLLAVTEHKDGMMEIVATPVTLIGQNGSPASLIDVKNFNENLILHSPIFQLNIEDIVDGSELQQPTEDIEPDVIATEQFKSQVCTEVKRTPTNQEYQCPPQNDLLVSKCDETAVQKPVSTDLKRNSPGRPKKNSAGSLQGTGSLKCDICHQEFVKRTLYRKHMENHAEEKPHRCPKCSASFNVPTNFTLHMATHNTGEPKCPECGKKFTRMASLKSHMLLHEKEENLFCTECEDAFSTKAQLDAHLKLHGEKWATEEARKCKLCNKQFGQPALYRLHIREHYRLQTKVVKQTKRGTKHKTVYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTVCSRAFTQKSSLQIHMWQHNGIRPHACELCNAKFSQKGNLNAHITRVHNVPEGEPIYGCNYCSCIFKKLGSLNGHMKRMHADIDEEGVATADRSDTVESDIRATVDSVITQLASLEATTEEAEKSNDKSNSSVSAKKDILQEALKNSGLPSKNKTANEGTENKKLGARTNFVTLLDRAADGGTRKYLTIKQRCVGNIRWYACTFCHKEFKKSSDLIRHLRVHTQEKPFKCTHCYRSFALKSTMIAHERTHSGTKRYACDSCDKSFACHGSLIGHTRLHAKAKNDCKMTDDDKKKVQAKKPKLSPEAESLVGQVVLQEPLVISDAGNKICVAQIASKEKRYDASTDPARPHKCWVCQAAFRKISHLKQHHRRHTGERPYECTKCDRRFTSNSVLKSHLHTHEDWRPYGCPTCDAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAQRQLEQQKMQEQSNQSVLKEGSKEILESSSFPTSANVATSTNVVNTPIVTTTAPTFTDNLTFSRLGTVEISFQSQLGSDFSQTFSEQDKARSLLTGSCEPSTFINHNVSETVMANLENSQMLHADETGSVTLPVYPGDQALTPESIREIEETLNQQFFNIGMNITLGNNSRNSNDVSTNDFDSTKVQQRQTVLNVMYENSGNDASNNTNNNNDSGNNGVEPSAERVFSSQLDSFEIDHIALQSDTEIDIGLDTNDSTSMTNILPRTVKEDRLTEVDQSVKSRVMVISQEKNPRKEVNELEAEEAIQKQSPLLLVEDFRGTEEKNQKVQHTGFAEIVNGKMQRDSSLQCHMCNQRGFTASGLKEHLKTHRETKEYQCTECSSKFCTNGGLNRHSKIHVTKQSWKCSSCDKYFDNRTELQSHNEIHEISIWNAISRPPNTESSDLQNGSLTDIAIDTDSAVSERVLLDTVAEKEAMDQIEASYTNPERREQKEYTNKCKFCPKTFRKPSDLIRHVRTHTGERPYKCDFCSKSFAVKCTLDSHTKVHTGKKTFRCHVCNSMFATKGSLKVHMRLHTGSKPFRCPVCDSRFRTSGHRKVHLLKHVREHKERPKRKQKHMKVAAIAEIAADLEKLGRTIGKTFESDQQLSRPLETISVEATACLTDQINFETDVDPNIVQSNNSVMNEGNQLVTNLHFLLTNGLVTIQTDESLLSQSNINNAYNRSTVATDSMCVPLCISSGINEDHTKEEVRPGQVLKAQLSSVQVELPKVPLDKSLPTGSKASKGNSRKECDVCGKTFTKPYQVERHKRIHTGERPYKCDLCTKSFAQKSTLQMHQKHHTGDRPYSCPYCEYSFTQKGNLRTHVKRVHQLDTINVKKLKRGRQYFLPKSLQDSVVETKTLNLDDVPFVEFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963973;
90% Identity: iTF_00963973; iTF_00964615; iTF_00961964; iTF_00963332;
80% Identity: -