Basic Information

Insect: Megachile lagopoda
Gene Symbol: ZNF236
Assembly: GCA_036983795.1
Location: CM072796.1:3768410-3775558[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0013 0.15 13.1 2.7 2 23 174 195 173 195 0.96

2 26 0.00011 0.013 16.5 1.1 1 23 201 223 201 223 0.98

3 26 1.5e-06 0.00018 22.4 0.7 2 23 229 250 229 250 0.97

4 26 0.008 0.92 10.7 0.2 3 23 258 278 256 278 0.96

5 26 0.00051 0.059 14.4 0.5 2 23 289 310 289 310 0.98

6 26 7.9e-07 9.2e-05 23.3 1.1 1 23 331 353 331 353 0.99

7 26 1.3e-05 0.0015 19.5 0.9 1 20 359 378 359 381 0.96

8 26 5.8e-05 0.0067 17.4 0.6 1 23 387 410 387 410 0.94

9 26 0.0082 0.95 10.6 2.3 3 23 421 442 419 442 0.97

10 26 3.9e-06 0.00045 21.1 3.0 1 23 567 589 567 589 0.98

11 26 0.00034 0.039 15.0 3.3 1 23 595 617 595 617 0.99

12 26 0.093 11 7.3 1.9 1 23 623 645 623 645 0.96

13 26 0.013 1.5 10.0 8.9 1 23 725 747 725 747 0.98

14 26 3.3e-05 0.0039 18.1 4.0 1 23 753 775 753 775 0.98

15 26 5.1e-05 0.0059 17.6 0.5 3 23 783 803 781 803 0.97

16 26 0.00043 0.05 14.6 7.6 1 23 809 831 809 831 0.98

17 26 0.03 3.5 8.8 1.2 2 23 1212 1233 1211 1233 0.96

18 26 0.0012 0.14 13.2 3.1 1 23 1239 1261 1239 1261 0.98

19 26 0.0096 1.1 10.4 0.7 2 23 1268 1289 1267 1289 0.94

20 26 5.8e-07 6.8e-05 23.7 1.6 2 23 1368 1389 1367 1389 0.98

21 26 0.0039 0.45 11.6 3.7 1 23 1395 1417 1395 1417 0.98

22 26 1.1e-05 0.0013 19.7 2.1 1 23 1423 1445 1423 1445 0.98

23 26 0.00073 0.084 13.9 2.5 1 23 1451 1473 1451 1473 0.98

24 26 5.3e-06 0.00061 20.7 0.6 2 23 1676 1697 1675 1697 0.97

25 26 1.4e-05 0.0017 19.3 4.5 1 23 1703 1725 1703 1725 0.98

26 26 8.4e-07 9.8e-05 23.2 0.7 1 23 1731 1754 1731 1754 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0013	0.15	13.1	2.7	2	23	174	195	173	195	0.96
2	26	0.00011	0.013	16.5	1.1	1	23	201	223	201	223	0.98
3	26	1.5e-06	0.00018	22.4	0.7	2	23	229	250	229	250	0.97
4	26	0.008	0.92	10.7	0.2	3	23	258	278	256	278	0.96
5	26	0.00051	0.059	14.4	0.5	2	23	289	310	289	310	0.98
6	26	7.9e-07	9.2e-05	23.3	1.1	1	23	331	353	331	353	0.99
7	26	1.3e-05	0.0015	19.5	0.9	1	20	359	378	359	381	0.96
8	26	5.8e-05	0.0067	17.4	0.6	1	23	387	410	387	410	0.94
9	26	0.0082	0.95	10.6	2.3	3	23	421	442	419	442	0.97
10	26	3.9e-06	0.00045	21.1	3.0	1	23	567	589	567	589	0.98
11	26	0.00034	0.039	15.0	3.3	1	23	595	617	595	617	0.99
12	26	0.093	11	7.3	1.9	1	23	623	645	623	645	0.96
13	26	0.013	1.5	10.0	8.9	1	23	725	747	725	747	0.98
14	26	3.3e-05	0.0039	18.1	4.0	1	23	753	775	753	775	0.98
15	26	5.1e-05	0.0059	17.6	0.5	3	23	783	803	781	803	0.97
16	26	0.00043	0.05	14.6	7.6	1	23	809	831	809	831	0.98
17	26	0.03	3.5	8.8	1.2	2	23	1212	1233	1211	1233	0.96
18	26	0.0012	0.14	13.2	3.1	1	23	1239	1261	1239	1261	0.98
19	26	0.0096	1.1	10.4	0.7	2	23	1268	1289	1267	1289	0.94
20	26	5.8e-07	6.8e-05	23.7	1.6	2	23	1368	1389	1367	1389	0.98
21	26	0.0039	0.45	11.6	3.7	1	23	1395	1417	1395	1417	0.98
22	26	1.1e-05	0.0013	19.7	2.1	1	23	1423	1445	1423	1445	0.98
23	26	0.00073	0.084	13.9	2.5	1	23	1451	1473	1451	1473	0.98
24	26	5.3e-06	0.00061	20.7	0.6	2	23	1676	1697	1675	1697	0.97
25	26	1.4e-05	0.0017	19.3	4.5	1	23	1703	1725	1703	1725	0.98
26	26	8.4e-07	9.8e-05	23.2	0.7	1	23	1731	1754	1731	1754	0.97

Sequence Information

Coding Sequence: ATGTTGACGCGACACGATATAATTACGGAAACTCCTCGCGTTGAGGCTATACCGATAAATCTTGTTACTACCGAGGATGGTAGAACGCTTTTGGCGGTGACAGaACACAAAGATGGTATGATGGAAATCGTTGCGACTCCTGTTACGCTTATTGGTCAAAACGGATCACCTGCGTCGTTGATtgatgtaaaaaattttaatgaaaacctAATATTGCATTCTCCTATTTTTCAACTGAACATAGAAGATATCGTTGATGGATCAGAATTGCAACAGTCTACGGAAGATATTGAACCTGATGCGATTACTACTGAACGGTTCAAATCGCAAATATGCACAGAGGTAAAGTGCAGAACACCCACTACCCAGGAGTACCAGTGTCCTCCACAAAATGATTTGTTAGTTAGTAAATGTGATGAAACTGCTGTACAAGAATCGGTAAGCGCAGACTTAAAAAGGAACAGCCCTGGAAGACCTAAGAAGAACTCAGCTGGTTCTTTACAGGGGACAGGAAGTTTAAAATGTGACATTTGCCATCAAGAATTCGTTAAACGGACGTTGTATCGGAAACATATGGAAAATCATGCCGAAGAGAAACCACATCGATGCCCAAAGTGCTCTGCATCCTTTAATGTTCCGACTAATTTCACTCTTCACATGGCGACTCATAATACGGGTGAACCAAAATGTCCAGAATGTGGAAAGAAGTTTACAAGGATGGCTAGTTTGAAGTCTCATATGTTGCTGCATGAGAAAGaggaaaatttgttttgtacTGAATGTGAAGATGCATTTTCAACTAAAGCTCAATTGGATGCGCATTTGAAGCTTCACGGAGAAAAATGGGCGACAGAAGAAGCACGAAAGTGTAAGCTATGCAATAAACAGTTTGGTCAACCGGCTTTGTACAGGCTTCATATTCGTGAACATTATAGGTTGCAGACGAAAGTGGTAAAGCAGACAAAAAGAGGGACAAAACATAAAACGGTGTACAAATGTACGATATGTTTAAAGTCTTTCCAAAAACCCAGTCAGTTAATGCGTCATATCAGAGTACACACCGGCGAAAAACCGTTCAAGTGTACAGTATGCAGTCGGGCGTTCACGCAAAAAAGTTCGCTCCAGATTCATATGTGGCAGCACAACGGTATTCGACCCCATGCTTGCGAGCTTTGCAATGCTAAATTCAGTCAAAAAGGTAATTTAAACGCTCACATAACAAGAGTTCATAATGTACCGGAGGGAGAGCCAATATATGGATGTAACTACTGTTCGTGCATATTCAAAAAGCTTGGCAGTTTAAACGGCCATATGAAGCGCATGCATGCCGACATAGACGAGGAAGGAGTTGCTACTACTGATACTCGCTCTGCTGACACCGTAGAATCCGACATACGGGCAACTGTGGACAGCGTTATAACGCAGTTGGCATCTTTAGAAGCGACCACGGACGAAGCTGAGAGATCGAATGACAAATCGAACTTATTATCGGTGGGCACGATGAAGAAAGATATTCTGCAAGAAGCACTGAAGAATAGTGGTCTGcctagtaaaaataaaagtgtgaACGAAGGTACAGCGGAAACGAAAAAACTTGGGGCGCGTACTAATTTTGTGACGTTACTGGATCGAGCGGCCGACGGCGGTACCAGaaaatatttgaccatCAAACAACGATGCGTGGGGAACATAAGATGGTATGCGTGTACCTTTTGCCACAAGGAGTTCAAGAAGTCGTCGGATTTGATACGACATTTACGCGTACACACGCAAGAGAAACCTTTCAAGTGTACCCATTGTTATCGTTCGTTCGCTCTGAAATCCACCATGATAGCACACGAACGCACTCATTCTGGCACGAAAAGATACGCTTGCGATTCTTGCGACAAATCATTCGCGTGTCATGGAAGTTTGATTGGCCATACTAGATTACATGCAAAATCTAAGAACGATTGCAATAAAACAATGGCTGACGACGACAAGAACACCGTCAATCGTACGAAAGTTCAAGCTAAGAGTAGACCGAAGTTATCGCCCGAAGCGGAGAGTTTGGTAGGCCAAGTGGTGTTACAAGAACCCTTGGTGATCAGTGATGCGGGGAATAAAATTTGCGTGGCACAAATAGCTTCGAAGGAGAAACGTTACGACGCGACTACCGATCCAGCTAGACCGCATAAATGTTGGGTTTGCCATGCAGCGTTTAGAAAGATCAGTCACTTGAAGCAACATCATCGTCGACACACGGGTGAACGTCCTTATGAATGCACCAAGTGCGACAGGAGGTTCACGTCGAACAGCGTGTTAAAGTCACATCTACACACACACGAGGATTGGAGACCGTACGGTTGTCCCACATGCGACGCGAAGTTTTCTACGCAAAGTAGCATGAAAAGGCATTTGGTTACTCACAGTAACAAAAGACCGTTCATGTGTCCGTATTGCCACAAGACTTTTAAAACCTACGTGAATTGTCGGAAACACATGAAGATACATAAACACGAATTAGCACAACGGCAGTTGGAGCAACAGAAAATCCAAATGCAAGAACAGTCATCGGACCAGTCGATTTTGAAAGAAGGTTCTAAAGAAACGACGATTCTCGAATCGAGTTCAACTTTTGTTCCTAACGCTACTAGTACAAACATTGTCGCCAATGCCCCTGCTATCGTTACAACGTCCGCTCCAACGTTTACAGACAATCTTACCTTTTCTCGCCTTGGCACGGTTGAGATATCGTTTCAGTCGCAGCTCGGTTCTGAtttttctcaaacttttaccGAGCAGGACAAAACGAGACCACTTTTATCCGGAAACTGCGAACCTTCAACTTTTATTAATCACAACGTATCGGAGACAGTAATGGCGAACCTTGAAAACTCACAGATGTTACATGCCGACGAAACTGGTTCTGTTACTTTGCCAGTTTATCCTGGTGATCAAGCACTCACACCGGAGAGCATACGAGAAATAGAAGAGACGTTGAATCAACAGTTTTTTAACATTGGGATGAACATTACTCTAGGAAATAATTCTAGACATTCGAACGACGTGAGCACGAATGATTTTGATAACACAAAGGTACAACAGCGACAAACCGTGTTGAATGTCATGTATGAGAACAGTGCTAATGACACTAGTAACAACACTagtaacaacaacaacaatgaCGGTGGTAACAACGTTGTTGTCGACGGTGTAGAACCATCCGAAGAACGTGTATTCTCTTCGCAGTTGGATTCGTTCGAGATTGATCATATCGCGTTACAATCGGACACTGAAATCGATATTGGATTGGATACGAACGATTCGACGAGTATGACGAATATACTGCCCAGGACCGTAAAAGAAGATCGTCTTCCTGTTTCCGAAGTTGACCGGGATCAATCAGGGAAGTCCACTTTGCAAAGGGTAATGGTCATTTCGCAAGAAAAGAATCTGCCAGGTAAAGAAGTAACGAACGAATTGGAAGCAACTGAAGAAGCCATTCGAAAGCAGCAAAGTCCATTGCTCTTGGTAGAAGATTTCCGGGGAACAGTAGAAGAGGAGATAAAGAATCAAACGAAAGTACAGCACACGACGTCATCCGGTTTTGCAGAAATTGTCAACGGTAAAATGCAGCGAGAATCTTCTTTGCAATGTCATATGTGCAATCAAAGAGGATTTACGGCGATCGGATTAAAGGAACATTTGAAGACTCATCGTGAAACTAAGGAATATCAGTGTACGGAATGctcttcaaaattttgcacGAACGGTGGCCTCAACAGACATTCGAAGATACATGTTACTAAACAaTCATGGAAGTGCTCCTCCTGCGAGAAATACTTTGATAACAGAACAGAGTTACAATCGCATAAcgaaattcatgaaatatctATTTGGAACGCTATATCCACAAGGCCACCGAACACGGAAAATTCAGATTTACAGCCAGTCGCGGATAACGGTTCGTCATTAAATGACATCGCGATAGATACCGACTCTGCAGTCTCCGAAAGAGTCTTATTGGACACCGTAGCAGAAAAAGAAGCGATGGATCAAATAGAAGCAAGTTACACGaatgtcCCAGGGGAGAGAAGGGAACGGAAGGAGTATACGAACAAGTGCAAATTTTGTCCGAAAACTTTTCGCAAACCAAGCGATCTTATAAGGCACGTGCGTACACATACGGGTGAACGACCGTATAAGTGCGATTTCTGCAGCAAAAGCTTCGCCGTGAAATGTACTCTGGATTCGCACACAAAAGTTCACACAGGCAAGAAAACGTTTCGGTGTCATGTTTGTAACAGCATGTTCGCGACCAAGGGTAGTCTAAAAGTCCACATGCGATTACATACAGGTTCTAAGCCGTTCAGATGTCCCGTTTGCGACTCGAGATTTAGGACGTCGGGTCACAGAAAAGTACATTTACTGAAACACGTGCGCGAGCACAAAGAGCGTCCAAAAAGGAAACAGAAGCATATGAAAGTTGCGGCTATAGCGGAAATAGCGGCTGATTTAGAAAAGCTAGGTAGAACCATAGGAAAGACGAGTTTCGAATCGGATCAGCAACTCTCTCGGGCAAAGGATTATCCTCAGTTGGAAACAATTAGCGTGGAAGCGACCGCTGCCTGTTTGACCGATCAGATCAACTTTGAGACCGAGGTTGATCCTAGTATCGTATCGAGTAATAATTCAGTGATGGCCACGAACGAAGGTAATCAGTTAGTTactaatttacattttctgcTAACCAACGGACTCGTGACCATCCAAACCGACGAATCGTTGTTGTCGCAATCGACAACGATTAACAATGCATCGTACAATCGTTCAACTGTGGCTGCTGACTCGATGTGCGTGCCAACACTCTGCATTTCATCCGGTATTAACGATGATCACACCAAGGAAGGAGTTCGTACGGGACAAGTGTTGAAGGCACAGTTATCGTCGATACAGGTGGAACAACCGTTACCAAAAGTTCCGCTCGATAAATCCCTGCCGACAGGAAGTAAAACGGCTAACAAAGGCAACTCGTCGAGGAAGGAGTGTGATGTTTGCGGGAAGACGTTTACGAAGCCGTATCAGGTTGAAAGGCATAAAAGAATTCATACGGGCGAGAGACCGTACAAGTGCGATCTCTGCACGAAATCGTTCGCCCAAAAATCTACTCTGCAAATGCATCAGAAACATCATACAGGAGATCGGCCGTACGCCTGCCCGTACTGCGAGTACTCTTTCACGCAGAAAGGCAATCTCCGAACCCACGTGAAACGGGTACACCAATTGGATACGATCAAcgttaagaaattgaaacgtGGTCGCCAGTATTTTCTACCTAAATCTCTTCAAGACAGCGTGGTCGAAACGAAGACTTTAAATTTGGACGACGTACCGTTCGTTGAATTCCTTAAATAG
Protein Sequence: MLTRHDIITETPRVEAIPINLVTTEDGRTLLAVTEHKDGMMEIVATPVTLIGQNGSPASLIDVKNFNENLILHSPIFQLNIEDIVDGSELQQSTEDIEPDAITTERFKSQICTEVKCRTPTTQEYQCPPQNDLLVSKCDETAVQESVSADLKRNSPGRPKKNSAGSLQGTGSLKCDICHQEFVKRTLYRKHMENHAEEKPHRCPKCSASFNVPTNFTLHMATHNTGEPKCPECGKKFTRMASLKSHMLLHEKEENLFCTECEDAFSTKAQLDAHLKLHGEKWATEEARKCKLCNKQFGQPALYRLHIREHYRLQTKVVKQTKRGTKHKTVYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTVCSRAFTQKSSLQIHMWQHNGIRPHACELCNAKFSQKGNLNAHITRVHNVPEGEPIYGCNYCSCIFKKLGSLNGHMKRMHADIDEEGVATTDTRSADTVESDIRATVDSVITQLASLEATTDEAERSNDKSNLLSVGTMKKDILQEALKNSGLPSKNKSVNEGTAETKKLGARTNFVTLLDRAADGGTRKYLTIKQRCVGNIRWYACTFCHKEFKKSSDLIRHLRVHTQEKPFKCTHCYRSFALKSTMIAHERTHSGTKRYACDSCDKSFACHGSLIGHTRLHAKSKNDCNKTMADDDKNTVNRTKVQAKSRPKLSPEAESLVGQVVLQEPLVISDAGNKICVAQIASKEKRYDATTDPARPHKCWVCHAAFRKISHLKQHHRRHTGERPYECTKCDRRFTSNSVLKSHLHTHEDWRPYGCPTCDAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAQRQLEQQKIQMQEQSSDQSILKEGSKETTILESSSTFVPNATSTNIVANAPAIVTTSAPTFTDNLTFSRLGTVEISFQSQLGSDFSQTFTEQDKTRPLLSGNCEPSTFINHNVSETVMANLENSQMLHADETGSVTLPVYPGDQALTPESIREIEETLNQQFFNIGMNITLGNNSRHSNDVSTNDFDNTKVQQRQTVLNVMYENSANDTSNNTSNNNNNDGGNNVVVDGVEPSEERVFSSQLDSFEIDHIALQSDTEIDIGLDTNDSTSMTNILPRTVKEDRLPVSEVDRDQSGKSTLQRVMVISQEKNLPGKEVTNELEATEEAIRKQQSPLLLVEDFRGTVEEEIKNQTKVQHTTSSGFAEIVNGKMQRESSLQCHMCNQRGFTAIGLKEHLKTHRETKEYQCTECSSKFCTNGGLNRHSKIHVTKQSWKCSSCEKYFDNRTELQSHNEIHEISIWNAISTRPPNTENSDLQPVADNGSSLNDIAIDTDSAVSERVLLDTVAEKEAMDQIEASYTNVPGERRERKEYTNKCKFCPKTFRKPSDLIRHVRTHTGERPYKCDFCSKSFAVKCTLDSHTKVHTGKKTFRCHVCNSMFATKGSLKVHMRLHTGSKPFRCPVCDSRFRTSGHRKVHLLKHVREHKERPKRKQKHMKVAAIAEIAADLEKLGRTIGKTSFESDQQLSRAKDYPQLETISVEATAACLTDQINFETEVDPSIVSSNNSVMATNEGNQLVTNLHFLLTNGLVTIQTDESLLSQSTTINNASYNRSTVAADSMCVPTLCISSGINDDHTKEGVRTGQVLKAQLSSIQVEQPLPKVPLDKSLPTGSKTANKGNSSRKECDVCGKTFTKPYQVERHKRIHTGERPYKCDLCTKSFAQKSTLQMHQKHHTGDRPYACPYCEYSFTQKGNLRTHVKRVHQLDTINVKKLKRGRQYFLPKSLQDSVVETKTLNLDDVPFVEFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963973;
90% Identity: iTF_00962646;
80% Identity: -