Mlig008646.1
Basic Information
- Insect
- Megachile ligniseca
- Gene Symbol
- -
- Assembly
- GCA_945859565.1
- Location
- CAMAOB010000054.1:458353-461724[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00015 0.015 16.1 1.9 1 23 100 123 100 123 0.93 2 12 0.0094 0.97 10.4 4.6 2 23 251 273 251 273 0.91 3 12 0.00028 0.029 15.2 1.5 2 23 317 339 316 339 0.95 4 12 5.3 5.4e+02 1.7 7.6 3 23 424 445 423 445 0.95 5 12 0.94 97 4.1 2.2 1 23 494 517 494 517 0.93 6 12 0.29 30 5.7 0.2 6 23 568 586 567 586 0.95 7 12 0.00015 0.015 16.1 0.1 3 23 607 628 606 628 0.94 8 12 0.0069 0.71 10.8 3.6 2 23 670 692 669 692 0.96 9 12 0.093 9.6 7.2 4.2 3 23 707 728 705 728 0.92 10 12 0.00024 0.024 15.4 0.1 2 23 772 794 772 794 0.94 11 12 0.12 12 6.9 1.7 1 23 873 895 873 895 0.98 12 12 0.00043 0.044 14.6 0.6 2 23 909 931 908 931 0.93
Sequence Information
- Coding Sequence
- ATGGCGAACGAGACGACGACGACGATATCGGAATTGACGGAATTGGACAGCGATGGATCGAGTTGCGGGGAACGGGACGTCAGGAAACGTCTCCGAGTTGACGCAGATTCGACCGGGCCGAAGAAGAGACGAAAACAGACGACCCCCGTAAGATTCTCGTCCGCGCTGATGATGAGCGGCGTGCACGAGGAGTCAAACGAGGACGAGGACGAGGACGAGGACAGCGAAGGTAAGCTGTCGTCGCAGTCACCAATACCGAGTCAATCGTCGATCAGGGACGAGAACCTCAATAACGAATTCCATTGCCAGTACTGCGGTCAGTTTTTCGATAGCAAGGATACGTTGAACGTTCACCTCGATAACGAGCACGGTTCCGCGAATCAGTCGTCTCAGCAGGGTCAAAGCGGATACGCGAGTAGCGCGATTAAACAGGAACCGTCTCAGCAACTGGACCAAACCGACACTCCCGTTAATCTGCTTAGCGTGAAGAATTTCGCGATAAATTGGCTGGCTACCGGACAACACGTGCAATCGCACGTGCAAATGCAGCCGCAGAACGAGGACTCGTGGCCGACCGGTACAGCCAGTCAAATCACCTCGTTGCCCAATCACCTGCAGGTACTCTCTTCCGGTTTCCCTGGTTCCTTGACGCAGTATCTATCTCTGCCCACGTTCCCGTTAACGGACTCCGGTCCGATCGCGAGATCCTCGATAGGACCGACGCCGGTGAGAATCTTTAATCCGGACGCGTACTGCGATCTGTGCAATAAAGAGTTCTGCAACAAGTATTTCCTGAAGACGCACAAGGCGAACAAGCACGGGATCTACGCGGATTCACCGGGACCCAGCTCGGTAGACAATAACGTCGTAACTCCCATGTATCCCGCTAACTTTTCTAGCAACTTTGTCAAACTGGAACCACCCGCGACGCCACCCACACCCAGCGTACCCTGTGACCTCTGCCAGAAACGCTTCAAGAACGAGGATTCGATGCGCAAGCACAAACAGAAAATGCACACCGATCTGCCGGATCAGTCGCAGGAACCGCAGATCAATCTATCGCAAAGCGAGGAGGATACGGAAACACCGAGAAACAATTTCGCGAGCATCGAGTCGTTTTTCAAACAGGAATACGGCGTGGAACAGGAGGACACATCGTTTATGCCTGCGCCTAGACACCTATCTCCCCAGTCGATTCAACAGGCACGGGACTCCGGTTTCAACGCTGATCGGCTTCGACGTTTAGGAGTGATAAATCCGGAGGCGTTCTGCGAGATCTGCTGTAAAGAGTACTGTAACAAGTACTTCCTACGAACGCATAAAATGAAGAGGCACGGTATCGTCGTTCAAGATAGCGAGAGGTCGCCGGGTAATCCAGGATCAGCGCCCACTTGGCATCAAGTGCAAACCAGCCCGTTAAATTTGATCGTAGCGGAGAGCGCCAGCAGCACCGAGTCGAACGAACGGCCAGGGGACGACTACGAGTGCAAACCCTGCGGAATACGATTCCAGACGATCGATCTTTATCAGACGCATTGCCGGAAGATGCACGAGAGCGAGGAGCAACGGTCGCCCAAGCAGGAGTGCGAACTGGAGACACCGACCGACCAGCCGAACGATTCCATCTCGGAGGATCTTCAAAAGTTGCAGACGATGCTGTTACAGCTGAACGGACTAAAATCCAGCAAGCAGGGATTGTCGTGCGGAAAGGAATACGACACCAGAACCGCGTTGCACATTCACGCGACGACCGAACACGCGTCCATCCCTGAAGATCCGACCTCGCCGCAAGAGAAGTCACCGTTGACGTCCATGCTCTGCACCCTTTGCGGGAAGGACTACGCTAGTCAGGACGCCCTCAGAAGACACATAGCGGAGGAACATCAGCCACCAACTATAAACACCCTTCCTCAAACACCCGCGACTACCTCCACCACGACCAACTCGAACGCGACGAGTCAAAGCACCTCCGAGAGGAAGGTGACGTCGATGACCCCCACGTCGAGCTACTGCGAGATATGCAACAAGGAGCTGTGCAATAAGTACTTCATGAAGACGCACATGCAGAGGATGCACGGCATCGAGATCGAGAACGGGGCTCAGATCGGTGGCGTGATATGCAACATCTGTAACAAAGAACTGTGCAGCAAGTACTTCCTGCGAGTGCACAAGCATAATACTCACGGAATAGTGGACGAGAATGCGCCCAGTTCGGTGAAACAAGAATCGCTCGAGGCCACGAACACCGACGATGCCCTGAAGCCGGAGCAACTCGGGGATTTGAGTCACAGGTACTTCACCCACTTTACGGAGGTTTGTCCGATCTGCAGCAGAAGGTTCCGCAGCATAAAGTGGCTGAAGGCTCACTTGATGGGCGAGCACGGGAAAGTGGGCATCGACAAATGGCGCGAGATGGAGCAACATTATCAGACAGCGTCCAGAACAACGAACAGAACCACTAGCACGCCGAAGAATACTCAACAGGGCTCGAACTTGAAGATACCGAACGGATTCGAGATTACGCAGCAGCTCAAGTCGACTGACTACACCGGTTTGGGGAACCAAGTGCTGTCTAATTTGCTGGGATCATCTTCCGAGGATCAACAACTGAAGAGCTATCGTTGTTCCTATTGTACGTTCACGACCACCGTGCTGCCGTTCCTCTTTCTTCACGAGAGATCTCACGTGCACTCCCGGGAAAACGCGGAGGGGGAGAAATCACTTCAGTGCCCGATTTGCTCGCAGAGCTTTCATCAGCCCGAGCTGTTGCATCAACATCTACTCGCGGCGCACCAGTTTCCCACGTTGTTGTCCCATTTTCCACCGCCGATGCTGAACAATTTAACACCCGACACGGAGAAACTGAACGAGGTCAAGGAGAGGCTGGAGTTGGAATCAAAAGAGGATCGTATCGGGAACAGTCCGCAAGTCACTGCCAACAAAAGCGTCCCGGAGCCGATCAGAAATCAACGACAAGACGACACAACGGTTCAAGTCACTCCTCAGGGTGTGTACAAGTGCGCGCAGTGTTGTTACGCCACGACCAATCTGAACAGGATCAAGAAGCACGTCAGAAAGGATCACAGGACCATCGGTGACCCCACCGACAGCGTGATAGCGGAGCTAGGTAGAACACTGAAGGACGTTGCCAACAGACACAAGATGCCGGCTTGCTACGCGATGCCGCAGGACATGAACTCGAATCCTGACAAAACTATCATGCAACCGTTCTTGATCGAGGAACAGGACGCGATGCAAGCCGGCGAGGAGTCCGGTTCGGATAAACGATTCGCGCCGGCTTTGGTTTATTTACCGGTTAAATCGAGAATTAACAACCCCCTCACCGCATCCTTCACCCTCAGCCCAGCTTGA
- Protein Sequence
- MANETTTTISELTELDSDGSSCGERDVRKRLRVDADSTGPKKRRKQTTPVRFSSALMMSGVHEESNEDEDEDEDSEGKLSSQSPIPSQSSIRDENLNNEFHCQYCGQFFDSKDTLNVHLDNEHGSANQSSQQGQSGYASSAIKQEPSQQLDQTDTPVNLLSVKNFAINWLATGQHVQSHVQMQPQNEDSWPTGTASQITSLPNHLQVLSSGFPGSLTQYLSLPTFPLTDSGPIARSSIGPTPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYADSPGPSSVDNNVVTPMYPANFSSNFVKLEPPATPPTPSVPCDLCQKRFKNEDSMRKHKQKMHTDLPDQSQEPQINLSQSEEDTETPRNNFASIESFFKQEYGVEQEDTSFMPAPRHLSPQSIQQARDSGFNADRLRRLGVINPEAFCEICCKEYCNKYFLRTHKMKRHGIVVQDSERSPGNPGSAPTWHQVQTSPLNLIVAESASSTESNERPGDDYECKPCGIRFQTIDLYQTHCRKMHESEEQRSPKQECELETPTDQPNDSISEDLQKLQTMLLQLNGLKSSKQGLSCGKEYDTRTALHIHATTEHASIPEDPTSPQEKSPLTSMLCTLCGKDYASQDALRRHIAEEHQPPTINTLPQTPATTSTTTNSNATSQSTSERKVTSMTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICNICNKELCSKYFLRVHKHNTHGIVDENAPSSVKQESLEATNTDDALKPEQLGDLSHRYFTHFTEVCPICSRRFRSIKWLKAHLMGEHGKVGIDKWREMEQHYQTASRTTNRTTSTPKNTQQGSNLKIPNGFEITQQLKSTDYTGLGNQVLSNLLGSSSEDQQLKSYRCSYCTFTTTVLPFLFLHERSHVHSRENAEGEKSLQCPICSQSFHQPELLHQHLLAAHQFPTLLSHFPPPMLNNLTPDTEKLNEVKERLELESKEDRIGNSPQVTANKSVPEPIRNQRQDDTTVQVTPQGVYKCAQCCYATTNLNRIKKHVRKDHRTIGDPTDSVIAELGRTLKDVANRHKMPACYAMPQDMNSNPDKTIMQPFLIEEQDAMQAGEESGSDKRFAPALVYLPVKSRINNPLTASFTLSPA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00224784;
- 90% Identity
- iTF_00962052; iTF_00964685; iTF_00962737;
- 80% Identity
- -