Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756256.1:4732647-4736030[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2.8e-05 0.0043 18.4 0.8 1 23 99 122 99 122 0.94

2 12 0.01 1.5 10.3 4.6 2 23 250 272 250 272 0.91

3 12 0.0003 0.044 15.2 1.5 2 23 316 338 315 338 0.95

4 12 5.6 8.4e+02 1.7 7.6 3 23 423 444 422 444 0.95

5 12 1 1.5e+02 4.1 2.2 1 23 493 516 493 516 0.93

6 12 0.0012 0.17 13.3 0.4 2 23 566 588 565 588 0.94

7 12 0.00011 0.017 16.5 0.1 3 23 611 632 609 632 0.93

8 12 0.0074 1.1 10.8 3.6 2 23 674 696 673 696 0.96

9 12 0.1 15 7.2 4.2 3 23 711 732 709 732 0.92

10 12 0.00025 0.038 15.4 0.1 2 23 776 798 776 798 0.94

11 12 0.12 19 6.9 1.7 1 23 877 899 877 899 0.98

12 12 0.00046 0.069 14.6 0.6 2 23 913 935 912 935 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2.8e-05	0.0043	18.4	0.8	1	23	99	122	99	122	0.94
2	12	0.01	1.5	10.3	4.6	2	23	250	272	250	272	0.91
3	12	0.0003	0.044	15.2	1.5	2	23	316	338	315	338	0.95
4	12	5.6	8.4e+02	1.7	7.6	3	23	423	444	422	444	0.95
5	12	1	1.5e+02	4.1	2.2	1	23	493	516	493	516	0.93
6	12	0.0012	0.17	13.3	0.4	2	23	566	588	565	588	0.94
7	12	0.00011	0.017	16.5	0.1	3	23	611	632	609	632	0.93
8	12	0.0074	1.1	10.8	3.6	2	23	674	696	673	696	0.96
9	12	0.1	15	7.2	4.2	3	23	711	732	709	732	0.92
10	12	0.00025	0.038	15.4	0.1	2	23	776	798	776	798	0.94
11	12	0.12	19	6.9	1.7	1	23	877	899	877	899	0.98
12	12	0.00046	0.069	14.6	0.6	2	23	913	935	912	935	0.93

Sequence Information

Coding Sequence: ATGGCGAACGAGACGACGACGATATCGGAATTGACGGAATTGGACAGCGATGGATCGAGTTGCGGGGAACGGGACGTCAGGAAACGTCTCCGAGTTGACGCAGATTCGACCGGGCCGAAGAAGAGACGAAAACAGACAACCCCCGTAAGATTCTCGTCCGCGCTGATGATGAGCGGCGTGCACGAGGAGTCGAACGAGGACGAGGACGAGGACGAGGACAGCGAAGGTAAGCTGTCGTCGCAGTCACCCATACCGAGTCAATCGTCGATCAGGGACGAGAACCTCAATAACGAATTCCGTTGCCAGTACTGCGGTCAGTTTTTCGATAGCAAGGATACGTTGAACGTTCACCTCGATAACGAGCACGGTTCCGCGAATCAGTCGTCTCAGCAGGGTCAAAGCGGATACTCGAGTAGCGCGATTAAACAGGAACCGTCTCAGCAACTGGACCAAACCGAGACTCCCGTTAATCTGCTTAGCGTGAAGAATTTCGCGATAAATTGGCTGGCTACCGGACAACACGTGCAATCGCACGTGCAAATGCAGCCGCAGAACGAGGACTCGTGGCCGGCCGGTACAGCCAGTCAAATCACCTCGTTGCCCAATCACCTGCAGGTACTCTCTTCCGGTTTCCCTGGTTCCTTGACGCAGTACCTATCTCTGCCCACGTTCCCGTTAACGGACTCCGGTCCGATCGCGAGATCCTCGATAGGACCGACGCCGGTGAGAATCTTTAATCCGGACGCGTACTGCGATCTGTGCAATAAAGAGTTCTGCAACAAGTATTTCCTGAAGACGCACAAGGCCAACAAGCACGGGATCTATGCGGATTCGCCGGGACCCAGCTCGGTAGACAATAACGTCGTTACTCCCATGTACCCCGCTAACTTTTCTAGCAATCTAGTCAAACTGGAACCACCCGCAACGCCACCCACACCCAGCGTACCCTGCGACCTGTGCCAGAAACGCTTCAAGAATGAGGATTCGATGCGCAAGCACAAACAGAAAATGCACACCGATCTGCCGGATCAGTCGCAGGAACCGCAGATCAATTTATCTCAGAACGAGGAGGATACGGAAACACCGAGAAACAATTTCGCGAGCATCGAGTCGTTTTTCAAACAGGAATACGGAGTGGAACAGGAGGACGCATCTTTCATGCCTGCGCCGAGACACCTATCTCCCCAGTCGATTCAACAGGCACGGGACTCCGGGTTTAACGCTGATCGGCTTCGACGCTTAGGGGTGATAAATCCGGAGGCGTTCTGCGAGATCTGCTGTAAAGAGTACTGTAACAAGTACTTCCTGCGGACGCATAAAATGAAGAGGCACGGCATCGTCGTTCAAGATAGCGAGAGGTCGCCGGGTAATCCAGGATCAGCGCCCACTTGGCATCAAGTGCAAACCAGCCCGTTAAATTTGATCGTGGCGGAGAGCGCCAGCAGTACCGAGTCGAACGAGCGGCCAGGGGACGACTACGAGTGCAAACCCTGCGGAATACGATTCCAGACCATCGATCTTTATCAGACGCATTGCCGGAAGATGCATGAAAGCGAGGAGCAGCGGTCCCCTAAGCAGGAGTGCGAACTGGAAACACCGACCGACCAGCCGAACGATTCCATCTCTGAGGATCTTCAGAAATTGCAGACGATGCTGTTACAGCTGAACGGACTGAAGTCCAGCAAGCAGGGACTGTCGTGCAACGTGTGCGGAAAGGAATACGACACCAGAACCGCGTTGCACATTCACGCGACGACCGAACACGCGTCCATCCCTGAAGACCCGACCTCGCCGCAGGAGAAGTCACCGTTGACCGCGACGTCCATGTTCTGCACCCTGTGCGGGAAGGACTACGCGAGTCAGGACGCTCTCAGAAGACACATAGCGGAGGAACATCAGCCACCGATTATGAACACCCTTCCTCAAACACCGGCGACTACCTCCACCACGACCAACTCGAACGCGACGAGTCAGAGCACCTCCGAGAGGAAGGTGACCTCGATGACGCCCACGTCGAGCTACTGCGAGATATGCAACAAGGAGCTGTGCAATAAGTACTTCATGAAGACCCACATGCAGAGGATGCACGGCATCGAGATCGAGAACGGTGCTCAGATCGGTGGCGTGATATGCAACATCTGCAACAAAGAACTGTGCAGTAAGTACTTCCTACGAGTGCACAAGCATAATACTCATGGAATAGTGGACGAGAACGCGCCTAGTTCGGTGAAACAAGAAGCGCTCGAGGCCACGAACACCGACGACGCCCTGAAGCCCGAGCAACTCGGGGATTTGAGTCACAGGTACTTCACCCACTTTACGGAGGTTTGTCCGATCTGCAGCAGAAGGTTCCGCAGCATAAAGTGGCTGAAGGCGCACTTGATGGGCGAGCACGGGAAAGTGGGCATCGACAAATGGCGCGAGATGGAGCAACATTATCAGACAGCGTCAAGAACAACGAACAGGACCACCAGCACTCCGAAGAATACTCAGCAGGGCTCGAACTTGAAGATTCCGAACGGATTCGAGATTACGCAGCAGCTGAAGTCGGCCGACTACACCGGCTTGGGGAACCAAGTGCTGTCTAATTTGCTGGGATCATCCTCCGAGGATCAACAACTGAAGAGCTATCGTTGTTCCTATTGTACGTTCACGACCACCGTGCTGCCGTTCCTCTTTCTTCACGAGAGATCTCACGTGCACTCCCGGGAAAACGCGGAGGGGGAGAAATCACTTCAGTGCCCGATTTGCTCGCAGAGCTTTCATCAGCCCGAGCTGTTGCATCAACATCTACTCGCGGCGCACCAGTTTCCCACGTTGTTGTCCCATTTTCCACCGCCAATGCTGAACAATTTAACACCCGACGCGGAGAAACTGAACGAGGTCAAGGAGAGGCTGGAGCTGGAGTCAAAGGAGGATCGTATCGGGAACAGCCCGCAAGTCACTGCCAACAAAAGCGTCCCGGAGCCGATCAGGAATCAACGACAGGACGACACGACGGTTCAAGTCACTCCTCAGGGTGTGTACAAGTGCGCGCAGTGTTGTTACGCCACGACAAACTTGAACAGGATCAAAAAGCACGTCAGAAAGGATCACAGGACCATCGGCGACCCCACCGACAGCGTGATAGCGGAGCTAGGTAGAACACTGAAGGACGTTGCCAACAGACACAAGATGCCGGCTTGCTACGCGATGCCGCAGGACATGAACTCGAATCCTGACAAAACTATCATGCAACCGTTCCTCATCGAGGAACAGGACGCGATGCAAGCCGGCGAGGAGTCCGGCTCGGATAAACGATTCGCGCCGGCTTTGGTTTATTTGCCGGTTAAATCGAGAATCAACAACCCCCTCACAGCATCCTTCACCCTCAGCCCCGCTTAA
Protein Sequence: MANETTTISELTELDSDGSSCGERDVRKRLRVDADSTGPKKRRKQTTPVRFSSALMMSGVHEESNEDEDEDEDSEGKLSSQSPIPSQSSIRDENLNNEFRCQYCGQFFDSKDTLNVHLDNEHGSANQSSQQGQSGYSSSAIKQEPSQQLDQTETPVNLLSVKNFAINWLATGQHVQSHVQMQPQNEDSWPAGTASQITSLPNHLQVLSSGFPGSLTQYLSLPTFPLTDSGPIARSSIGPTPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYADSPGPSSVDNNVVTPMYPANFSSNLVKLEPPATPPTPSVPCDLCQKRFKNEDSMRKHKQKMHTDLPDQSQEPQINLSQNEEDTETPRNNFASIESFFKQEYGVEQEDASFMPAPRHLSPQSIQQARDSGFNADRLRRLGVINPEAFCEICCKEYCNKYFLRTHKMKRHGIVVQDSERSPGNPGSAPTWHQVQTSPLNLIVAESASSTESNERPGDDYECKPCGIRFQTIDLYQTHCRKMHESEEQRSPKQECELETPTDQPNDSISEDLQKLQTMLLQLNGLKSSKQGLSCNVCGKEYDTRTALHIHATTEHASIPEDPTSPQEKSPLTATSMFCTLCGKDYASQDALRRHIAEEHQPPIMNTLPQTPATTSTTTNSNATSQSTSERKVTSMTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICNICNKELCSKYFLRVHKHNTHGIVDENAPSSVKQEALEATNTDDALKPEQLGDLSHRYFTHFTEVCPICSRRFRSIKWLKAHLMGEHGKVGIDKWREMEQHYQTASRTTNRTTSTPKNTQQGSNLKIPNGFEITQQLKSADYTGLGNQVLSNLLGSSSEDQQLKSYRCSYCTFTTTVLPFLFLHERSHVHSRENAEGEKSLQCPICSQSFHQPELLHQHLLAAHQFPTLLSHFPPPMLNNLTPDAEKLNEVKERLELESKEDRIGNSPQVTANKSVPEPIRNQRQDDTTVQVTPQGVYKCAQCCYATTNLNRIKKHVRKDHRTIGDPTDSVIAELGRTLKDVANRHKMPACYAMPQDMNSNPDKTIMQPFLIEEQDAMQAGEESGSDKRFAPALVYLPVKSRINNPLTASFTLSPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00224784;
90% Identity: iTF_00963435;
80% Identity: -